LU X, Shi Y, Gao F, Xiao H, et al. Insights into avian influenza virus pathogenicity: the hemagglutinin precursor HA0 of H16 subtype has an alpha-helix structure in its cleavage site with an inefficient HA1/HA2 cleavage. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22993148)
With a new serotype (H17) hemagglutinin (HA) recently being discovered, there are now 17 serotypes (H1-H17) of influenza A viruses in total. It is believed that HA is initially expressed as a precursor ... AYLLON J, Russell RJ, Garcia-Sastre A, Hale BG, et. Contribution of NS1 effector domain dimerization to influenza A virus replication and virulence. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22993153)
Conserved tryptophan-187 facilitates homodimerization of the influenza A virus NS1 effector domain. We generated a mutant influenza virus expressing NS1-W187R to destabilize this self-interaction. NS1-W187R ... SCHLAUDECKER EP, McNeal MM, Dodd CN, Ranz JB, et a. Pregnancy Influences the Antibody Response to Trivalent Influenza Immunization. J Infect Dis. 2012. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22984116)
We report the immunogenicity of trivalent influenza immunization in 29 pregnant compared to 22 non-pregnant women. We obtained blood on day 0 prior to 2011-2012 influenza vaccine administration, and day ... CHO JH, Kim CD, Kim MS, Kang ES, et al. The impact of A(H1N1)pdm09 infection on renal transplant recipients: a multicenter cohort study. J Infect. 2012;65:88-90. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Infect. 2012;65:88-90 (via http://www.ncbi.nlm.nih.gov/pubmed/22522290)
2009 H1N1 influenza infection in cancer patients and hematopoietic stem cell transplant recipients. NELSON M, Detmer SE, Wentworth DE, Tan Y, et al. Genomic reassortment of influenza A virus in North American swine, 1998-2011. J Gen Virol. 2012.. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Gen Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22993190)
Revealing the frequency and determinants of reassortment among RNA genome segments is fundamental to understanding basic aspects of the biology and evolution of the influenza virus. To estimate the extent ... SMIEJA M. Review: Oseltamivir relieves symptoms but does not reduce hospitalizations in influenza. Ann Intern Med. 2012;157:JC3-5. Abstract
submitted by kickingbird at Sep, 24, 2012 from Ann Intern Med. 2012;157:JC3-5 (via http://www.ncbi.nlm.nih.gov/pubmed/22986397)
QUESTIONS Are neuraminidase inhibitors effective for preventing or treating influenza in adults and children who are not immunocompromised? What are the harms? REVIEW SCOPE Included studies compared neuraminidase ... Taubenberger JK, et al.. Reconstruction of the 1918 Influenza Virus: Unexpected Rewards from the Past. mBio 3(5):e00201-12. doi:10.1128/mBio.00201-12.. Abstract
submitted by kickingbird at Sep, 15, 2012 from mBio 3(5):e00201-12. doi:10.1128/mBio.00201-12. (via http://mbio.asm.org:80/content/3/5/e00201-12)
The influenza pandemic of 1918–1919 killed approximately 50 million people. The unusually severe morbidity and mortality associated with the pandemic spurred physicians and scientists to isolate the etiologic ... KOWALCZYK A, Markowska-Daniel I, Rasmussen TB. Development of a primer-probe energy transfer based real-time PCR for the detection of Swine Influenza Virus. J Virol Methods. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from J Virol Methods. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22944078)
Swine influenza virus (SIV) causes a contagious and requiring official notification disease of pigs and humans. In this study, a real-time reverse transcription-polymerase chain reaction (RT-PCR) assay ... EDENBOROUGH KM, Gilbertson BP, Brown LE. A mouse model for the study of contact-dependent transmission of influenza A virus and the factors that govern transmissibility. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22951824)
Influenza A virus transmission by direct contact is not well characterized. Here we describe a mouse model for investigation of factors regulating contact-dependent transmission. Strains within the H3N2 ... LI W, Moltedo B, Moran TM.. Type I IFN induction during influenza infection increases the susceptibility to secondary S. pneumoniae Infection by negative regulation of gammadelta T cells. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22951826)
The majority of deaths following influenza infection result from secondary bacterial superinfection, most commonly caused by Streptococcus pneumoniae. Several models have been proposed to explain how primary ... SHI M, Jagger BW, Wise HM, Digard P, et al. Evolutionary conservation of the PA-X open reading frame in segment 3 of influenza A virus. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22951836)
PA-X is a fusion protein of influenza A virus encoded in part from a +1 frameshifted 'X-ORF' in segment 3. We show that the X-ORF of diverse influenza A viruses can be divided into two groups that differ ... VAN WIELINK R, Harmsen MM, Martens DE, Peeters BP,. Mutations in the M gene segment can substantially increase replication efficiency of NS1 deletion influenza A virus in MDCK cells. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22951840)
Influenza viruses unable to express NS1 protein (delNS1) replicate poorly and induce high amounts of interferon (IFN). They are therefore considered as candidate viruses for live-attenuated influenza vaccines. ... TAYLOR AK, Cao W, Vora KP, Cruz JD, et al. Protein Energy Malnutrition Decreases Immunity and Increases Susceptibility to Influenza Infection in Mice. J Infect Dis. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22949306)
Background.?Protein energy malnutrition (PEM), a common cause of secondary immune deficiency in children, is associated with an increased risk of infections. Very few studies have addressed the relevance ... QI X, Cui L, Jiao Y, Pan Y, et al. Antigenic and genetic characterization of a European avian-like H1N1 swine influenza virus from a boy in China in 2011. Arch Virol. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from Arch Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22935945)
Cross-species transmission of influenza A viruses from swine to human occurs occasionally. In 2011, an influenza A H1N1 virus, A/Jiangsu/ALS1/2011 (JS/ALS1/2011), was isolated from a boy who suffered from ... CHEUNG CY, Chan EY, Krasnoselsky A, Purdy D, et al. H5N1 Virus Causes Significant Perturbations in Host Proteome Very Early in Influenza Virus-Infected Primary Human Monocyte-Derived Macrophages. J Infect Dis. 2012. Abstract
submitted by kickingbird at Aug, 1, 2012 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22822004)
H5N1 influenza viruses, which cause disease in humans, have unusually high pathogenicity. The temporal response of primary human monocyte-derived macrophages infected with highly pathogenic H5N1 and seasonal ... WEINHEIMER VK, Becher A, Tonnies M, Holland G, et. Influenza A viruses target type II pneumocytes in the human lung. J Infect Dis. 2012.. Abstract
submitted by kickingbird at Aug, 1, 2012 from J Infect Dis. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22829640)
Background.?Highly pathogenic avian H5N1 influenza viruses preferentially infect alveolar type II pneumocytes in human lung. However, it is unknown whether this cellular tropism contributes to high viral ... NIEMANN S, Ehrhardt C, Medina E, Warnking K, et al. The Combined Action of Influenza Virus and Staphylococcus aureus Panton-Valentine Leukocidin Provokes Severe Lung Epithelium Damage. J Infect Dis. 2012. Abstract
submitted by kickingbird at Aug, 1, 2012 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22837490)
S. aureus necrotizing pneumonia is a life-threatening disease that is frequently preceded by an influenza infection. The S. aureus toxin Panton-Valentine leukocidin (PVL) is most likely causative for necrotizing ... GUTIERREZ-PIZARRAYA A, Perez-Romero P, Alvarez R,. Unexpected severity of cases of influenza B infection in patients that required hospitalization during the first postpandemic wave. J Infect. 2012. Abstract
submitted by kickingbird at Aug, 1, 2012 from J Infect. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22820034)
Abstract
OBJECTIVES:
After the last pandemic the knowledge regarding influenza A infection has improved however, the outcomes of influenza B infection remain poorly studied. The aim of this study was ... PENA L, Vincent AL, Loving CL, Henningson JN, et a. Strain-dependent Effects of PB1-F2 of Triple Reassortant H3N2 Influenza Viruses in Swine. J Gen Virol. 2012. Abstract
submitted by kickingbird at Aug, 1, 2012 from J Gen Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22815274)
The PB1-F2 protein of the influenza A viruses (IAV) can act as a virulence factor in mice. Its contribution to the virulence of IAV in swine, however, remains largely unexplored. In this study, we chose ... HUANG P, Liang LJ, Hou NM, Zhang X, et al. Phylogenetic, molecular and drug-sensitivity analysis of HA and NA genes of human H3N2 influenza A viruses in Guangdong, China, 2007-2011. Epidemiol Infect. 2012. Abstract
submitted by kickingbird at Aug, 1, 2012 from Epidemiol Infect. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22827898)
SUMMARY Annual H3N2 subtype influenza outbreaks in Guangdong, China are a severe public health issue and require ongoing monitoring of emerging viral variants. The variation and evolution of haemagglutinin ... 7516 items, 20/Page, Page[275/376][|<<] [|<] [271] [272] [273] [274] [275] [276] [277] [278] [279] [280] [>|] [>>|] |
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