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2026-10-7 12:58:39
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Elizabeth Billington, etc.,al. [preprint]The mammalian-adaptive PB2-E627K substitution preserves viral fitness of clade 2.3.4.4b H5N1 HPAIV in birds. https://doi.org/10.64898/2026.10.06.757006.  Abstract  
submitted by kickingbird at 48 minute(s) ago from https://doi.org/10.64898/2026.10.06.757006 (via https://www.biorxiv.org/content/10.64898/2026.10.06.757006v1)
Since emerging in 2020, clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus (HPAIV) has disseminated globally, causing substantial infection and mortality in wild birds and poultry. Additionally, ...

Ruth N, Shakya M, Lewis CD, Erickson CE, Dolinski. Mallard super-shedders of avian influenza exhibit distinct cloacal microbial abundance profiles. Microbiol Spectr. 2026 Oct 6:e0208926.  Abstract  
submitted by kickingbird at 5 hours ago from Microbiol Spectr. 2026 Oct 6:e0208926 (via https://journals.asm.org/doi/10.1128/spectrum.02089-26)
In many infectious disease systems, a small fraction of hosts accounts for a disproportionate share of transmission, but the biological basis of this heterogeneity remains poorly resolved. In avian influenza, ...

Del Rosario JMM, van Diemen PM, Frost SDW, Vishwan. A digitally immune-optimized influenza vaccine broadly neutralizes swine and human H1N1 influenza viruses and protects from heterologous challenge. J Virol. 2026 Oct 6:e0107326.  Abstract  
submitted by kickingbird at 5 hours ago from J Virol. 2026 Oct 6:e0107326 (via https://journals.asm.org/doi/10.1128/jvi.01073-26)
Influenza A virus (IAV) zoonotic transmission and continuous evolution in multiple host species heighten the risk of emerging novel strains at the human-animal interface. Digitally immune-optimized hemagglutinin ...

Zhang, X., Deng, X., Liang, Y. et al. Associations between vaccine misinformation and influenza vaccine uptake: a population-based interrupted time-series study in China. npj Digit. Public Health 1, 40 (2026).  Abstract  
submitted by kickingbird at 5 hours ago from npj Digit. Public Health 1, 40 (2026) (via https://link.springer.com/article/10.1038/s44482-026-00047-1)
Vaccine misinformation is linked to vaccine hesitancy, yet real-world evidence of its association with vaccine uptake remains limited. Most existing studies rely on self-reported intentions or experimental ...

Nooruzzaman M, Buchholz DW, Rani R, de Oliveira PS. Infection and transmission dynamics of bovine and human influenza A H5N1 viruses in mouse and hamster models. Pathogenesis and Host Response.  Abstract  
submitted by kickingbird at 6 hours ago from Pathogenesis and Host Response (via https://journals.asm.org/doi/10.1128/jvi.01044-26)
Here we investigated the pathogenesis and contact transmission of bovine- and human-derived highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b genotype B3.13 viruses in mammalian models. Using ...

Guo T, Ming B, Liang Y, Lu F, Ma W, Zhang J. Role-specific household contact patterns in urban and rural China: Implications for influenza household transmission. Infect Dis Model. 2026 Sep 2;12(1):154-169.  Abstract  
submitted by kickingbird at 18 hours ago from Infect Dis Model. 2026 Sep 2;12(1):154-169 (via https://www.sciencedirect.com/science/article/pii/S246804272)
Background: Household contact patterns significantly influence the household transmission dynamics of respiratory pathogens. Previous studies have shown ignoring the heterogeneity of household contact ...

Lin Z, Chen J, Su G, Wang H, Deng R, Tian S, Yang. Persistent influenza A RNA detection in a fatal pediatric case of influenza-associated encephalopathy. J Infect Public Health. 2026 Oct 1;19(11):103380.  Abstract  
submitted by kickingbird at 18 hours ago from J Infect Public Health. 2026 Oct 1;19(11):103380 (via https://www.sciencedirect.com/science/article/pii/S187603412)
Influenza-associated encephalopathy (IAE) is a life-threatening complication of influenza. We report a case of a 9-year-old boy diagnosed with fulminant IAE. The patient received life-sustaining support, ...

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