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2025-12-5 16:05:12
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An Y, Ding X, Tian Y, Zhang M, Ma Y, Wu X, Cai M,. High-throughput pseudovirus neutralisation maps the antigenic landscape of influenza A/H1N1 viruses. EBioMedicine. 2025 Dec 2;122:106047.  Abstract  
submitted by kickingbird at 6 hours ago from EBioMedicine. 2025 Dec 2;122:106047 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: The continuous mutations in the haemagglutinin gene in A/H1N1 influenza viruses drives antigenic drift, necessitating frequent vaccine updates. Pseudovirus systems, with their flexible HA protein ...

Huddleston J, Bedford T. Timely vaccine strain selection and genomic surveillance improve evolutionary forecast accuracy of seasonal influenza A/H3N2. Elife. 2025 Dec 4;14:RP104282.  Abstract  
submitted by kickingbird at 7 hours ago from Elife. 2025 Dec 4;14:RP104282 (via https://elifesciences.org/articles/104282)
Evolutionary forecasting models inform seasonal influenza vaccine design by predicting which current genetic variants will dominate in the influenza season 12 months later. Forecasting models depend on ...

Frutos AM, Moon S, Binder AM, Cool AJ, Iyawe K, Th. Evaluation of a Novel Data Source for National Influenza Surveillance: Influenza Hospitalization Data in the National Healthcare Safety Network, United States, September 2021-April 2024. Am J Public Health. 2025 Dec 4:e1-e5.  Abstract  
submitted by kickingbird at 7 hours ago from Am J Public Health. 2025 Dec 4:e1-e5 (via https://ajph.aphapublications.org/doi/full/10.2105/AJPH.2025)
Objectives. To evaluate the completeness and utility of influenza hospital data reported to the Centers for Disease Control and Prevention's National Healthcare Safety Network (NHSN) from September 2021 ...

ECDC. Scenarios for pre-pandemic zoonotic influenza preparedness and response. ECDC.  Abstract  
submitted by kickingbird at 7 hours ago from ECDC (via https://www.ecdc.europa.eu/en/publications-data/scenarios-pr)
We have defined 14 scenarios based on specific epidemiological and virological factors, including animal origin, characteristics of human cases (number and exposure context), severity signals, that are ...

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