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2020-2-25 5:32:16
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Humphreys JM, et al. Waterfowl occurrence and residence time as indicators of H5 and H7 avian influenza in North American Poultry. Sci Rep. 2020 Feb 13;10(1):2592..  Abstract  
submitted by kickingbird at 8 days ago from Sci Rep. 2020 Feb 13;10(1):2592. (via https://www.ncbi.nlm.nih.gov/pubmed/32054908)
Avian influenza (AI) affects wild aquatic birds and poses hazards to human health, food security, and wildlife conservation globally. Accordingly, there is a recognized need for new methods and tools to ...

Tuong HT, Nguyen NM, Sung HW, Park H, Yeo SJ. Genetic Characterization of Avian Influenza A (H11N9) Virus Isolated from Mandarin Ducks in South Korea in 2018. Viruses. 2020 Feb 12;12(2).  Abstract  
submitted by kickingbird at 8 days ago from Viruses. 2020 Feb 12;12(2) (via https://www.mdpi.com/1999-4915/12/2/203)
In July 2018, a novel avian influenza virus (A/Mandarin duck/South Korea/KNU18-12/2018(H11N9)) was isolated from Mandarin ducks in South Korea. Phylogenetic and molecular analyses were conducted to characterize ...

Richard M, et al. Influenza A viruses are transmitted via the air from the nasal respiratory epithelium of ferrets. Nat Commun. 2020 Feb 7;11(1):766.  Abstract  
submitted by kickingbird at 15 days ago from Nat Commun. 2020 Feb 7;11(1):766 (via https://www.ncbi.nlm.nih.gov/pubmed/32034144)
Human influenza A viruses are known to be transmitted via the air from person to person. It is unknown from which anatomical site of the respiratory tract influenza A virus transmission occurs. Here, pairs ...

Zhang Q. Human genetics of life-threatening influenza pneumonitis. Hum Genet. 2020 Feb 5.  Abstract  
submitted by kickingbird at Feb, 9, 2020 from Hum Genet. 2020 Feb 5 (via https://www.ncbi.nlm.nih.gov/pubmed/32025908)
Influenza viruses infect millions of people around the globe annually, usually causing self-limited upper respiratory tract infections. However, a small but non-negligible proportion of patients suffer ...

Gao F, et al. MiRNA Targeted NP Genome of Live Attenuated Influenza Vaccines Provide Cross-Protection against a Lethal Influenza Virus Infection. Vaccines (Basel). 2020 Feb 3;8(1)..  Abstract  
submitted by kickingbird at Feb, 9, 2020 from Vaccines (Basel). 2020 Feb 3;8(1). (via https://www.ncbi.nlm.nih.gov/pubmed/32028575)
The miRNA-based strategy has been used to develop live attenuated influenza vaccines. In this study, the nucleoprotein (NP) genome segment of the influenza virus was inserted by different perfect miRNA-192-5p ...

Abed Y, et al. Molecular pathway of influenza pan-neuraminidase inhibitor resistance in an immunocompromised patient. Antivir Ther. 2020 Feb 7.  Abstract  
submitted by kickingbird at Feb, 9, 2020 from Antivir Ther. 2020 Feb 7 (via https://www.intmedpress.com/journals/avt/abstract.cfm?id=334)
BACKGROUND: Neuraminidase (NA) inhibitors (NAIs), including oseltamivir and zanamivir, play an important therapeutic role against influenza infections in immunocompromised patients. In such settings, however, ...

Reimering S, Mu?oz S, McHardy AC. Phylogeographic reconstruction using air transportation data and its application to the 2009 H1N1 influenza A pandemic. PLoS Comput Biol. 2020 Feb 7;16(2):e1007101.  Abstract  
submitted by kickingbird at Feb, 9, 2020 from PLoS Comput Biol. 2020 Feb 7;16(2):e1007101 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Influenza A viruses cause seasonal epidemics and occasional pandemics in the human population. While the worldwide circulation of seasonal influenza is at least partly understood, the exact migration patterns ...

He W, et al. Adaption and Parallel Evolution of Human-Isolated H5 Avian Influenza Viruses. J Infect. 2020 Jan 30. pii: S0163-4453(20)30036-0..  Abstract  
submitted by kickingbird at Feb, 5, 2020 from J Infect. 2020 Jan 30. pii: S0163-4453(20)30036-0. (via https://www.journalofinfection.com/article/S0163-4453(20)300)
Avian-to-human transmission of highly pathogenic avian influenza viruses (HPAIV) and their subsequent adaptation to humans are of great concern to public health. Surveillance and early warning of AIVs ...

Xu C, et al. A single amino acid at position 431 of the PB2 protein determines the virulence of H1N1 swine influenza viruses in mice. J Virol. 2020 Jan 29. pii: JVI.01930-19.  Abstract  
submitted by kickingbird at Feb, 5, 2020 from J Virol. 2020 Jan 29. pii: JVI.01930-19 (via https://jvi.asm.org/content/early/2020/01/23/JVI.01930-19)
Genetic reassortments occurred continuously among multiple subtypes or genotypes of influenza viruses prevalent in pigs. Of note, some reassortant viruses bearing the internal genes of 2009 pandemic H1N1 ...

Skarlupka AL, et al. An influenza HA Computationally Optimized Broadly Reactive Antigen elicits antibodies endowed with group-1 heterosubtypic breadth against swine influenza viruses. J Virol. 2020 Jan 29. pii: JVI.02061-19..  Abstract  
submitted by kickingbird at Feb, 5, 2020 from J Virol. 2020 Jan 29. pii: JVI.02061-19. (via https://jvi.asm.org/content/early/2020/01/23/JVI.02061-19)
Computationally Optimized Broadly Reactive Antigens (COBRA) designed for different influenza virus subtypes (H1N1, H3N2 and H5N1) elicit a subtype-specific broad antibody (Ab) response in na?ve as well ...

Fusade-Boyer M, et al. Risk Mapping of Influenza D Virus Occurrence in Ruminants and Swine in Togo Using a Spatial Multicriteria Decision Analysis Approach. Viruses. 2020 Jan 21;12(2)..  Abstract  
submitted by kickingbird at Jan, 28, 2020 from Viruses. 2020 Jan 21;12(2). (via https://www.mdpi.com/1999-4915/12/2/128)
Influenza D virus (IDV) has been identified in several continents, with serological evidence for the virus in Africa. In order to improve the sensitivity and cost-benefit of IDV surveillance in Togo, risk ...

Zheng B, Zhou J, Wang H. Host microRNAs and exosomes that modulate influenza virus infection. Virus Res. 2020 Jan 22:197885..  Abstract  
submitted by kickingbird at Jan, 28, 2020 from Virus Res. 2020 Jan 22:197885. (via https://www.sciencedirect.com/science/article/abs/pii/S01681)
MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate over half of human protein-coding genes and play a vital role in cellular development, proliferation, metabolism, and homeostasis. ...

Guo J, et al. Mouse adaptation of the H9N2 avian influenza virus causes the downregulation of genes related to innate immune responses and ubiquitin-mediated proteolysis in mice. Med Microbiol Immunol. 2020 Jan 25..  Abstract  
submitted by kickingbird at Jan, 28, 2020 from Med Microbiol Immunol. 2020 Jan 25. (via https://link.springer.com/article/10.1007%2Fs00430-020-00656)
H9N2 avian influenza viruses sporadically infect humans worldwide. These viruses have also contributed internal genes to H5N1, H5N6, H7N9, and H10N8 viruses, which have been isolated from humans with infections ...

Hicks JT, et al. Agricultural and geographic factors shaped the North American 2015 highly pathogenic avian influenza H5N2 outbreak. PLoS Pathog. 2020 Jan 21;16(1):e1007857.  Abstract  
submitted by kickingbird at Jan, 25, 2020 from PLoS Pathog. 2020 Jan 21;16(1):e1007857 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The 2014-2015 highly pathogenic avian influenza (HPAI) H5NX outbreak represents the largest and most expensive HPAI outbreak in the United States to date. Despite extensive traditional and molecular epidemiological ...

Everett HE, et al. Interspecies Transmission of Reassortant Swine Influenza A Virus Containing Genes from Swine Influenza A(H1N1)pdm09 and A(H1N2) Viruses. Emerg Infect Dis. 2020 Feb;26(2):273-281..  Abstract  
submitted by kickingbird at Jan, 25, 2020 from Emerg Infect Dis. 2020 Feb;26(2):273-281. (via https://wwwnc.cdc.gov/eid/article/26/2/19-0486_article)
Influenza A(H1N1)pdm09 (pH1N1) virus has become established in swine in the United Kingdom and currently co-circulates with previously enzootic swine influenza A virus (IAV) strains, including avian-like ...

Neumann G. Influenza Reverse Genetics-Historical Perspective. Cold Spring Harb Perspect Med. 2020 Jan 21..  Abstract  
submitted by kickingbird at Jan, 25, 2020 from Cold Spring Harb Perspect Med. 2020 Jan 21. (via http://perspectivesinmedicine.cshlp.org/content/early/2020/0)
The generation of wild-type, mutant, and reassortant influenza viruses from viral cDNAs (reverse genetics) is now a basic molecular virology technique in many influenza virus laboratories. Here, I describe ...

Lee DH, Criado MF, Swayne DE. Pathobiological Origins and Evolutionary History of Highly Pathogenic Avian Influenza Viruses. Cold Spring Harb Perspect Med. 2020 Jan 21..  Abstract  
submitted by kickingbird at Jan, 25, 2020 from Cold Spring Harb Perspect Med. 2020 Jan 21. (via http://perspectivesinmedicine.cshlp.org/content/early/2020/0)
High-pathogenicity avian influenza (HPAI) viruses have arisen from low-pathogenicity avian influenza (LPAI) viruses via changes in the hemagglutinin proteolytic cleavage site, which include mutation of ...

Wang D, Zhu W, Yang L, Shu Y. The Epidemiology, Virology, and Pathogenicity of Human Infections with Avian Influenza Viruses. Cold Spring Harb Perspect Med. 2020 Jan 21.  Abstract  
submitted by kickingbird at Jan, 25, 2020 from Cold Spring Harb Perspect Med. 2020 Jan 21 (via http://perspectivesinmedicine.cshlp.org/content/early/2020/0)
Influenza is a global challenge, and future pandemics of influenza are inevitable. One of the lessons learned from past pandemics is that all pandemic influenza viruses characterized to date possess viral ...

Kombiah S, et al. Experimental pathology of two highly pathogenic H5N1 viruses isolated from crows in BALB/c mice. Microb Pathog. 2020 Jan 20:103984..  Abstract  
submitted by kickingbird at Jan, 25, 2020 from Microb Pathog. 2020 Jan 20:103984. (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
In our study we assessed the pathogenicity of two H5N1 viruses isolated from crows in mice. Eighteen 6-8 weeks BALB/c mice each were intranasally inoculated with 106 EID50/ml of H5N1 viruses A/crow/India/03CA04/2015 ...

Root JJ, Ellis JW, Shriner SA. Effects of freshwater crayfish on influenza A virus persistence in water. Zoonoses Public Health. 2020 Jan 20..  Abstract  
submitted by kickingbird at Jan, 21, 2020 from Zoonoses Public Health. 2020 Jan 20. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/zph.12688)
Several investigations have recently assessed the ability of some aquatic invertebrates to act as tools for avian influenza A virus (IAV) surveillance as well as their potential role(s) in IAV ecology. ...

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