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2026-6-24 7:38:55
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Sopko J, Han AR, Powers J, Sauer JA, Avunoori M, Z. Multimodal Data Approaches for Examining the 2024-2025 Highly Pathogenic Avian Influenza Outbreak in the United States: Descriptive Study. JMIR Public Health Surveill. 2026 Jun 22;12:e86209.  Abstract  
submitted by kickingbird at 23 hours ago from JMIR Public Health Surveill. 2026 Jun 22;12:e86209 (via https://publichealth.jmir.org/2026/1/e86209)
Background: Highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b, a globally predominant strain, was introduced into poultry in the United States in 2022 via spillover from wild birds, and has ...

Akin E, Villafuerte DA, Werner AP, Pinsley M, Pier. Emergence of an antigenically drifted and reassorted influenza B virus at the end of the 2024-25 influenza season. mBio 0:e01198-26.  Abstract  
submitted by kickingbird at 23 hours ago from mBio 0:e01198-26 (via https://journals.asm.org/doi/10.1128/mbio.01198-26)
Influenza B virus (IBV) is a significant contributor to annual and severe cases of influenza, particularly in the young and elderly. Late in the 2024-25 Northern Hemisphere influenza season, a surge of ...

Hammed Olawale Fatoyinbo, Hoyeon Jeong. [preprint]Spatiotemporal dynamics and ecological risk factors of highly pathogenic avian influenza A(H5N1) in Canadian wildlife: A One Health surveillance analysis. https://doi.org/10.48550/arXiv.2605.22352.  Abstract  
submitted by kickingbird at 2 days ago from https://doi.org/10.48550/arXiv.2605.22352 (via https://arxiv.org/html/2605.22352v1)
Highly pathogenic avian influenza A(H5N1) has expanded geographically and ecologically, affecting wild birds, mammalian wildlife, domestic animals, and humans. Wildlife surveillance provides critical early ...

Gao X, Yu H, Zhang N, Liu L, Tong J, Qi X, Huang H. Epidemiological and Virological Characteristics of H9N2 Avian Influenza Virus in Jiangsu Province, China, 2024. Viruses. 2026; 18(6):687.  Abstract  
submitted by kickingbird at 3 days ago from Viruses. 2026; 18(6):687 (via https://www.mdpi.com/1999-4915/18/6/687)
H9N2 avian influenza viruses inherently carry cross-species transmission potential, making continuous surveillance critical for pandemic prevention. This study focused on monitoring the 2024 H9N2 epidemic ...

Cole C, Cleven T, Henige M, Poulsen K, Maroney M,. Innate Pathway Selection Modulates Antibody and T-Cell Responses to Mosaic Influenza Nucleoprotein in Cattle. Viruses. 2026; 18(6):670.  Abstract  
submitted by kickingbird at 4 days ago from Viruses. 2026; 18(6):670 (via https://www.mdpi.com/1999-4915/18/6/670)
Highly pathogenic avian influenza (HPAI) is a lethal disease of poultry that has recently spilled over into mammals, including dairy cattle and humans, heightening concerns for livestock health, food security, ...

Carrie Julia Moore, Kira Zachmann, Susanne Lackner. Wastewater genomic surveillance of influenza A and B reveals seasonal and off-season circulation differences between municipal sites and an international airport, Germany, 2024. Water Research.  Abstract  
submitted by kickingbird at 4 days ago from Water Research (via https://www.sciencedirect.com/science/article/abs/pii/S00431)
Wastewater surveillance has proved to be a valuable tool for monitoring human pathogens. Whole-genome sequencing of SARS-CoV-2 in wastewater has been extensively applied, allowing for early detection of ...

Puduo Zhu, etc.,al. Characterization and Pathogenicity of a Novel Triple-Reassortant H6N6 Avian Influenza Virus Associated with Reproductive Failure in Breeding Ducks. Poultry Science.  Abstract  
submitted by kickingbird at 4 days ago from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
H6N6 avian influenza virus (AIV) has emerged as a predominant subtype in recent years, with frequent isolations reported in China, Vietnam, and South Korea. As critical reservoirs, waterfowl play a pivotal ...

Jin, X., Han, P., Wang, Y. et al. Hemagglutinin double-mutation enhances binding of human-infecting avian influenza virus clade 2.3.4.4b H5Ny to human and SLeX receptors. EMBO Rep (2026).  Abstract  
submitted by kickingbird at 4 days ago from EMBO Rep (2026) (via https://link.springer.com/article/10.1038/s44319-026-00816-2)
Clade 2.3.4.4b H5Ny highly pathogenic avian influenza viruses (HPAIVs) continue to circulate worldwide, posing zoonotic threats, especially with recent cattle outbreaks. The mechanisms by which these viruses ...

Srinivas S, Chothe SK, Ramasamy S, Misra S, Nallip. Receptor basis of unusual tissue tropism of avian influenza H5N1 clade 2.3.4.4b virus in cattle. Sci Adv. 2026 Jun 19;12(25):eaea2068.  Abstract  
submitted by kickingbird at 4 days ago from Sci Adv. 2026 Jun 19;12(25):eaea2068 (via https://www.science.org/doi/10.1126/sciadv.aea2068)
The unusual tropism of H5N1 clade 2.3.4.4b for cattle mammary glands, causing necrotizing mastitis without major respiratory involvement, raises critical questions about its underlying mechanisms. We conducted ...

James Baxter, etc.,al. [preprint]The Winners Take It All? Global Evolutionary Success of H5Nx Reassortants in the 2020–2024 Panzootic. https://doi.org/10.1101/2025.07.19.66568.  Abstract  
submitted by kickingbird at 6 days ago from https://doi.org/10.1101/2025.07.19.66568 (via https://www.biorxiv.org/content/10.1101/2025.07.19.665680v2)
Avian influenza viruses undergo frequent genetic reassortment, which can coincide with phenotypic changes in transmission, pathogenicity, and host species niche. Since 2020, clade 2.3.4.4b H5 high pathogenicity ...

Anna Jaeggi-Wong, etc.,al. [preprint]Antibodies to influenza A virus hemagglutinin and neuraminidase limit egress and alter the physical properties of released virus particles. https://doi.org/10.64898/2026.06.15.729605.  Abstract  
submitted by kickingbird at 6 days ago from https://doi.org/10.64898/2026.06.15.729605 (via https://www.biorxiv.org/content/10.64898/2026.06.15.729605v1)
Influenza A virus (IAV)-specific antibodies neutralize mature virions by inhibiting functional sites or, in some cases, by promoting virion aggregation. Many antibodies also act on infected cells to reduce ...

Zhou Y, Wang P, Li S, Sun F, Zhu M, Wang R, Dong S. The N-terminal region of pdm09/H1N1 PA synergizes with its cognate NP to enhance mammalian adaptation of avian-origin H9N2 canine influenza virus. Vet Microbiol. 2026 Jun 15;320:111120.  Abstract  
submitted by kickingbird at 6 days ago from Vet Microbiol. 2026 Jun 15;320:111120 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
The PA gene of the 2009 pandemic H1N1 (pdm09/H1N1) lineage is derived from avian influenza virus (AIV). Together with other polymerase subunits, it enhances the adaptation of avian-origin influenza virus ...

Alnaji, F.G., Farjo, M., Goh, S.L. et al. Longitudinal analysis of influenza A virus deletion-containing viral genomes reveals key determinants of co-evolutionary dynamics and interference. Nat Commun (2026).  Abstract  
submitted by kickingbird at 6 days ago from Nat Commun (2026) (via https://www.nature.com/articles/s41467-026-74526-7)
Influenza A virus populations contain substantial genetic diversity. A major contributor to this diversity is the ubiquitous production of deletion-containing viral genomes (DelVGs) - viral RNAs with large ...

Ihazmade H, Regragui Z, Bimouhen A, Belbacha I, Fa. Genetic variations on influenza virus infection outcomes in Moroccan patients. Iran J Microbiol. 2026 Jun;18(3):357-366..  Abstract  
submitted by kickingbird at 6 days ago from Iran J Microbiol. 2026 Jun;18(3):357-366. (via https://doi.org/10.18502/ijm.v18i3.21662)
Background and objectives: The influenza infection remains a significant global health challenge, it leads to illnesses that vary from mild to severe, and in certain cases, death. The innate immune response ...

Savegnago E, Cavicchio L, Dianati M, Salomoni A, Z. Host Species Contribution to the Spatiotemporal Dynamics of the 2024-2025 H5N1 Epidemic in Italy. Influenza Other Respir Viruses. 2026 Jun;20(6):e70.  Abstract  
submitted by kickingbird at 7 days ago from Influenza Other Respir Viruses. 2026 Jun;20(6):e70 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/irv.70279)
This study uses a phylodynamic approach to investigate host species contribution in the spatiotemporal dynamics of the highly pathogenic avian influenza A(H5N1) viruses of clade 2.3.4.4b identified during ...

Nabil NM, Tawakol MM, Hagag N, Eid S, Brierley L,. Molecular surveillance and predictive risk modelling of avian influenza virus in wild birds in Egypt. J Gen Virol. 2026 Jun;107(6).  Abstract  
submitted by kickingbird at 7 days ago from J Gen Virol. 2026 Jun;107(6) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Avian influenza viruses (AIVs) continue to circulate and pose a persistent threat to animal and public health in Egypt, a country located along major migratory birds' flyways that enable repeated viral ...

Zhao S, Chen Y, Zhang T, Gao Y, Wu J, Yang F, Liu. Degradation of ACSL3 by influenza A virus shifts unfolded protein response from antiviral defense to viral evasion. Virol Sin. 2026 Jun 13:S1995-820X(26)00097-0.  Abstract  
submitted by kickingbird at 8 days ago from Virol Sin. 2026 Jun 13:S1995-820X(26)00097-0 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Host restriction factors and viral evasion strategies involved in the virus-host arms races remain to be discovered. Through an initial membrane protein-targeted CRISPR-Cas9 screening, we identified Acyl-CoA ...

Chen X, Dong J, Zhao C, Wang L, Gao X, Li Z, Sun H. Dominant HA motif 131/132-NT shapes the phenotype of avian H9N2 influenza virus by modulating agglutination property, receptor specificity and infectivity in animals. Virol Sin. 2026 Jun 13:S1995-820X(26)00096-9.  Abstract  
submitted by kickingbird at 8 days ago from Virol Sin. 2026 Jun 13:S1995-820X(26)00096-9 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
H9N2 avian influenza viruses (AIVs), which are enzootic in poultry and possess spillover potential to humans, represent a considerable global public health threat. Since 2021, we have observed an unprecedented ...

Hui X, Tian X, Xue C, Ding S, Cui J, Sun A, Lu W,. KCMF1-mediated influenza A virus PB1 ubiquitination at K653 regulates viral replication. J Virol 0:e00481-26.  Abstract  
submitted by kickingbird at 8 days ago from J Virol 0:e00481-26 (via https://journals.asm.org/doi/10.1128/jvi.00481-26)
Ubiquitination is a pivotal regulatory mechanism in host-virus interactions, playing essential roles in both antiviral defense and viral immune evasion, with E3 ubiquitin ligases serving as critical regulatory ...

Nguyen X, Le BT, Bleich J, Espada C, Zhang W, Wan. Environmental temperature and relative humidity shape post-emission aerosol fate and airborne influenza transmission. J Virol 0:e00634-26.  Abstract  
submitted by kickingbird at 8 days ago from J Virol 0:e00634-26 (via https://journals.asm.org/doi/10.1128/jvi.00634-26)
Airborne transmission is a major route of influenza virus spread, yet how environmental conditions shape the persistence and downrange transport of infectious exhaled virions is not fully understood. Using ...

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