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2023-6-8 7:09:08
Article

Stevens L, de Buyl S, Mognetti BM. The sliding motility of the bacilliform virions of Influenza A viruses. Soft Matter. 2023 Jun 6.  Abstract  
submitted by kickingbird at 21 hours ago from Soft Matter. 2023 Jun 6 (via https://pubs.rsc.org/en/content/articlelanding/2023/SM/D3SM0)
Influenza A virus (IAV) infection relies on the action of the hemagglutinin (HA) and neuraminidase (NA) membrane proteins. The HA ligands anchor the IAV virion to the cell's surface by binding the sialic ...

Yehia N, Rabie N, Adel A, Mossad Z, Nagshabandi MK. Differential replication characteristic of reassortant avian influenza A viruses H5N8 clade 2.3.4.4b in Madin-Darby canine kidney cell. Poult Sci. 2023 Mar 29;102(7):102685.  Abstract  
submitted by kickingbird at 4 days ago from Poult Sci. 2023 Mar 29;102(7):102685 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Late in 2016, multiple reassortant highly pathogenic (HP) avian influenza virus (AIVs) H5N8 was detected. AIVs infect different isolated hosts with a specific viral tropism. In the current study, the whole ...

Wang C, Honce R, Salvatore M, Chow D, Randazzo D,. Influenza Defective Interfering Virus Promotes Multiciliated Cell Differentiation and Reduces the Inflammatory Response in Mice. J Virol. 2023 May 31:e0049323.  Abstract  
submitted by kickingbird at 5 days ago from J Virol. 2023 May 31:e0049323 (via https://journals.asm.org/doi/10.1128/jvi.00493-23)
Influenza defective interfering (DI) viruses have long been considered promising antiviral candidates because of their ability to interfere with replication-competent viruses and induce antiviral immunity. ...

Meng B, Li H, Feng C, Guo W, Feng Y, Zhu D, Chen H. Emergence of a novel reassortant H3N6 canine influenza virus. Front Microbiol. 2023 May 11;14:1186869.  Abstract  
submitted by kickingbird at 8 days ago from Front Microbiol. 2023 May 11;14:1186869 (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1186)
Although the natural hosts of avian influenza viruses (AIVs) are wild birds, multiple subtypes of AIVs have established epidemics in numerous mammals due to their cross-species spillover. Replication and ...

Nico Halwe, etc al. The bat-borne influenza A virus H9N2 exhibits a set of unexpected pre-pandemic features. Research Square.  Abstract  
submitted by kickingbird at 9 days ago from Research Square (via https://www.researchsquare.com/article/rs-2937503/v1)
An Old-World bat H9N2 influenza A virus (IAV) identified in Egypt exhibits high replication and transmission potential in ferrets, efficient infection of human lung explant cultures and marked escape from ...

Schuele C, Schmeisser F, Orr M, Meseda CA, Vasudev. Neutralizing and protective murine monoclonal antibodies to the hemagglutinin of influenza H5 clades 2.3.2.1 and 2.3.4.4. Influenza Other Respir Viruses. 2023 May;17(5):e13.  Abstract  
submitted by kickingbird at 9 days ago from Influenza Other Respir Viruses. 2023 May;17(5):e13 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13152)
Background: Highly pathogenic avian H5 influenza viruses have spread and diversified genetically and antigenically into multiple clades and subclades. Most isolates of currently circulating H5 viruses ...

Liu Y, Wang Y, Wang Y, Mai H, Chen Y, Zhang Y, Ji. Phylogenetic analysis of HA and NA genes of influenza A viruses in immunosuppressed inpatients in Beijing during the 2018-2020 influenza seasons. Virol J. 2023 May 26;20(1):101.  Abstract  
submitted by kickingbird at 10 days ago from Virol J. 2023 May 26;20(1):101 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Influenza A viruses have undergone rapid evolution with virulent; however, complete and comprehensive data on gene evolution and amino acid variation of HA and NA in immunosuppressed patients ...

Ning H, Chiu SH, Xu X, Ma Y, Chen JL, Yang G. The Immunosuppressive Roles of PD-L1 during Influenza A Virus Infection. Int J Mol Sci. 2023 May 11;24(10):8586.  Abstract  
submitted by kickingbird at 10 days ago from Int J Mol Sci. 2023 May 11;24(10):8586 (via https://www.mdpi.com/1422-0067/24/10/8586)
The clinical benefits of targeting programmed death-ligand 1 (PD-L1) in various cancers represent a strategy for the treatment of immunosuppressive diseases. Here, it was demonstrated that the expression ...

An SH, Hong SM, Song JH, Son SE, Lee CY, Choi KS,. Engineering an Optimal Y280-Lineage H9N2 Vaccine Strain by Tuning PB2 Activity. Int J Mol Sci. 2023 May 16;24(10):8840.  Abstract  
submitted by kickingbird at 10 days ago from Int J Mol Sci. 2023 May 16;24(10):8840 (via https://www.mdpi.com/1422-0067/24/10/8840)
H9N2 avian influenza A viruses (AIVs) cause economic losses in the poultry industry and provide internal genomic segments for the evolution of H5N1 and H7N9 AIVs into more detrimental strains for poultry ...

Agustiningsih A, Indalao IL, Pangesti KA, Sukowati. Molecular Characterization of Influenza A/H3N2 Virus Isolated from Indonesian Hajj and Umrah Pilgrims 2013 to 2014. Life (Basel). 2023 Apr 27;13(5):1100.  Abstract  
submitted by kickingbird at 10 days ago from Life (Basel). 2023 Apr 27;13(5):1100 (via https://www.mdpi.com/2075-1729/13/5/1100)
The Hajj and Umrah are the annual mass gatherings of Muslims in Saudi Arabia and increase the transmission risk of acute respiratory infection. This study describes influenza infection among pilgrims upon ...

Guan L, Zhong G, Fan S, Plisch EM, Presler R, Gu C. Highly Pathogenic H5 Influenza Viruses Isolated between 2016 and 2017 in Vietnamese Live Bird Markets. Viruses. 2023 Apr 29;15(5):1093.  Abstract  
submitted by kickingbird at 10 days ago from Viruses. 2023 Apr 29;15(5):1093 (via https://www.mdpi.com/1999-4915/15/5/1093)
Routine surveillance in live poultry markets in the northern regions of Vietnam from 2016 to 2017 resulted in the isolation of 27 highly pathogenic avian H5N1 and H5N6 viruses of 3 different clades (2.3.2.1c, ...

Sharshov K, Dubovitskiy N, Derko A, Loginova A, Ko. Does Avian Coronavirus Co-Circulate with Avian Paramyxovirus and Avian Influenza Virus in Wild Ducks in Siberia?. Viruses. 2023 May 7;15(5):1121.  Abstract  
submitted by kickingbird at 10 days ago from Viruses. 2023 May 7;15(5):1121 (via https://www.mdpi.com/1999-4915/15/5/1121)
Avian coronaviruses (ACoV) have been shown to be highly prevalent in wild bird populations. More work on avian coronavirus detection and diversity estimation is needed for the breeding territories of migrating ...

Jakob C, Lovate GL, Desirò D, Gie?ler L, Smyth RP,. Sequential disruption of SPLASH-identified vRNA-vRNA interactions challenges their role in influenza A virus genome packaging. Nucleic Acids Res. 2023 May 24:gkad442.  Abstract  
submitted by kickingbird at 13 days ago from Nucleic Acids Res. 2023 May 24:gkad442 (via https://academic.oup.com/nar/advance-article/doi/10.1093/nar)
A fundamental step in the influenza A virus (IAV) replication cycle is the coordinated packaging of eight distinct genomic RNA segments (i.e. vRNAs) into a viral particle. Although this process is thought ...

Wang X, Lin L, Chen Z, Si W, Yan Y, Dong W, Jin Y,. Mutations at site 207 of influenza a virus NS1 protein switch its function in regulating RIG-I-like receptors mediated antiviral responses. Antiviral Res. 2023 May 23:105641.  Abstract  
submitted by kickingbird at 13 days ago from Antiviral Res. 2023 May 23:105641 (via https://www.sciencedirect.com/science/article/pii/S016635422)
RIG-I-like receptors (RLRs), retinoic acid inducible gene I (RIG-I) and melanoma differentiation-associated protein 5 (MDA5), are pattern recognition receptors through which cells initially sense pathogenic ...

Liang Y, Sun Z, Hua W, Li D, Han L, Liu J, Huo L,. Spatiotemporal effects of meteorological conditions on global influenza peaks. Environ Res. 2023 May 23:116171.  Abstract  
submitted by kickingbird at 13 days ago from Environ Res. 2023 May 23:116171 (via https://www.sciencedirect.com/science/article/abs/pii/S00139)
Background: Numerous studies have suggested that meteorological conditions such as temperature and absolute humidity are highly indicative of influenza outbreaks. However, the explanatory power of meteorological ...

Yang J, Zhang C, Yuan Y, Sun J, Lu L, Sun H, Sun H. Novel Avian Influenza Virus (H5N1) Clade 2.3.4.4b Reassortants in Migratory Birds, China. Emerg Infect Dis. 2023 Jun;29(6):1244-1249.  Abstract  
submitted by kickingbird at May, 22, 2023 from Emerg Infect Dis. 2023 Jun;29(6):1244-1249 (via https://wwwnc.cdc.gov/eid/article/29/6/22-1723_article)
Two novel reassortant highly pathogenic avian influenza viruses (H5N1) clade 2.3.4.4b.2 were identified in dead migratory birds in China in November 2021. The viruses probably evolved among wild birds ...

Lee SH, Cho AY, Kim TH, Ahn SJ, Song JH, Lee H, Ch. Novel Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus in Wild Birds, South Korea. Emerg Infect Dis. 2023 May 19;29(7).  Abstract  
submitted by kickingbird at May, 22, 2023 from Emerg Infect Dis. 2023 May 19;29(7) (via https://pubmed.ncbi.nlm.nih.gov/37204922/)
We isolated 5 highly pathogenic avian influenza A(H5N1) clade 2.3.4.4.b viruses from wild waterfowl feces in South Korea during November 2022. Whole-genome sequencing and phylogenetic analysis revealed ...

Sreenivasan CC, Liu R, Gao R, Guo Y, Hause BM, Tho. Influenza C and D Viruses Demonstrated a Differential Respiratory Tissue Tropism in a Comparative Pathogenesis Study in Guinea Pigs. J Virol. 2023 May 18:e0035623.  Abstract  
submitted by kickingbird at May, 19, 2023 from J Virol. 2023 May 18:e0035623 (via https://journals.asm.org/doi/10.1128/jvi.00356-23)
Influenza C virus (ICV) is increasingly associated with community-acquired pneumonia (CAP) in children and its disease severity is worse than the influenza B virus, but similar to influenza A virus associated ...

Ferrando VA, Friedrich ME, Gandhi S, Mellmann A, M. Cell-intrinsic genomic reassortment of pandemic H1N1 2009 and Eurasian avian-like swine influenza viruses results in potentially zoonotic variants. Emerg Microbes Infect. 2023 May 16:2212809.  Abstract  
submitted by kickingbird at May, 17, 2023 from Emerg Microbes Infect. 2023 May 16:2212809 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Influenza A viruses (IAV) cause annual epidemics and occasional pandemics in humans. The most recent pandemic outbreak occurred in 2009 with H1N1pdm09. This virus, which most likely reassorted in swine ...

Mazel-Sanchez B, Niu C, Williams N, Bachmann M, Ch. Influenza A virus exploits transferrin receptor recycling to enter host cells. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e221.  Abstract  
submitted by kickingbird at May, 17, 2023 from Proc Natl Acad Sci U S A. 2023 May 23;120(21):e221 (via https://www.pnas.org/doi/10.1073/pnas.2214936120)
Influenza A virus (IAV) enters host cells mostly through clathrin-dependent receptor-mediated endocytosis. A single bona fide entry receptor protein supporting this entry mechanism remains elusive. Here ...

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