Giacomo De Conti, etc.,al. [preprint]A GIS-based framework for standardized environmental characterization in One-Health surveillance: a case study of HPAI monitoring in wetlands. https://doi.org/10.21203/rs.3.rs-10456544/v1. Abstract
submitted by kickingbird at 5 hours ago from https://doi.org/10.21203/rs.3.rs-10456544/v1 (via https://www.researchsquare.com/article/rs-10456544/v1)
BackgroundThe Highly Pathogenic Avian Influenza (HPAI) panzootic caused by H5 viruses of clade 2.3.4.4b is constantly re-shaping disease ecology in terms of spatio-temporal spread and host spectrum. Because ... Denise I.T. Kuok, etc.,al. Assessment of influenza virus and coronavirus tropism, replication competence and disease severity in ex vivo and in vitro cultures of the human respiratory tract. Journal of General Virology 107, 002281 (2026) Jul. Abstract
submitted by kickingbird at 1 days ago from Journal of General Virology 107, 002281 (2026) Jul (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
The emergence of animal influenza viruses circulating in poultry and human populations poses a significant public health threat, yet current risk assessment tools that connect surveillance data to human ... Mohammed Nooruzzaman, etc.,al. Characterization of bovine-derived H5N1 viruses expressing fluorescent and luminescent reporter proteins. Journal of General Virology 107, 002298 (2026). Abstract
submitted by kickingbird at 1 days ago from Journal of General Virology 107, 002298 (2026) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Highly pathogenic avian influenza H5N1 clade 2.3.4.4b viruses present a broad host range, with recent spillover and sustained transmission in dairy cattle reported in the USA. Replication-competent reporter ... Wille M, Abbott W, Day D, Deng YM, Dong X, Gibson. Skuas as sentinels of high pathogenicity avian influenza H5N1 on the Antarctic Peninsula in the 2024/2025 austral summer. Microb Genom. 2026 Aug;12(8). Abstract
submitted by kickingbird at 1 days ago from Microb Genom. 2026 Aug;12(8) (via https://www.microbiologyresearch.org/content/journal/mgen/10)
Despite Antarctica's geographic isolation, the first incursion of high pathogenicity avian influenza (HPAI) H5N1 was detected in the 2023/2024 austral summer. Surveillance for HPAI H5N1 in Antarctica remains ... Dema B, Ulaszewska M, Lilley A, Lofts A, Bhasin R,. Assessment of Humoral Immunogenicity of ChAdOx1 H5 HA Influenza Vaccine for Dairy Cattle. Vaccines. 2026; 14(8):691. Abstract
submitted by kickingbird at 2 days ago from Vaccines. 2026; 14(8):691 (via https://www.mdpi.com/2076-393X/14/8/691)
Background/objectives: The emergence of highly pathogenic avian influenza A (H5N1) virus infections in dairy cattle in the United States revealed a novel mammalian host and a potential transmission pathway ... Rovito SW, Chen P-L, Yang G, Writt HN, Zalla AN, D. An In Vitro Screen Identifies H1 Influenza Hemagglutinin Substitutions That Alter mRNA-LNP Vaccine Responses Against the Stalk Domain. Vaccines. 2026; 14(8):701. Abstract
submitted by kickingbird at 2 days ago from Vaccines. 2026; 14(8):701 (via https://www.mdpi.com/2076-393X/14/8/701)
Background: Conformational stability has been shown to modulate the immunogenicity of structural class 1 viral fusion glycoproteins, yet the relationship between influenza A hemagglutinin (HA) stability ... Lauring AS, Papalambros L, Fitzsimmons WJ, Bendall. Whole genome sequencing of influenza virus transmission pairs confirms the efficacy of baloxavir in reducing household transmission. Clin Infect Dis. 2026 Aug 13:ciag489. Abstract
submitted by kickingbird at 2 days ago from Clin Infect Dis. 2026 Aug 13:ciag489 (via https://academic.oup.com/cid/advance-article/doi/10.1093/cid)
Background: The CENTERSTONE study demonstrated that treatment of influenza cases with baloxavir significantly reduced the transmission of influenza viruses to household contacts. Because transmission was ... Vega-Macaya F, Díaz-Gavidia C, Sánchez-Rodríguez F. Transboundary Spread and Ecological Drivers of HPAI H5N1 Clade 2.3.4.4b During the 2022-2023 Outbreak in Chile: An Integrated Genomic and Spatial Epidemiology Framework. Transbound Emerg Dis. 2026;2026(1):e1266281. Abstract
submitted by kickingbird at 3 days ago from Transbound Emerg Dis. 2026;2026(1):e1266281 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/1266281)
The 2022-2023 outbreak of highly pathogenic avian influenza (HPAI) H5N1 in Chile caused extensive mortality in wild birds, domestic poultry, and marine mammals, highlighting the rapid transboundary spread ... Wei Wang, etc.,al. Pre-existing hemagglutinin-specific antibody levels are associated with B-cell repertoire maturation and antibody breadth after influenza vaccination. Virologica Sinica. Abstract
submitted by kickingbird at 4 days ago from Virologica Sinica (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Repeated influenza exposures generate complex antibody landscapes, yet how pre-existing antibodies are associated with subsequent vaccine responses remains unclear. We longitudinally tracked 21 adults ... Forna A, Damodaran L, Gunning CE, Rahimi P, Venkat. Alignment-free prediction of cross-reactivity in influenza A (H3N2) anticipates antigenic drift. PLoS Comput Biol. 2026 Aug 11;22(8):e1014628. Abstract
submitted by kickingbird at 4 days ago from PLoS Comput Biol. 2026 Aug 11;22(8):e1014628 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Since its introduction in 1968, Influenza A (H3N2) has undergone continuous antigenic evolution, necessitating frequent vaccine updates. To predict antigenicity and characterize antigenic drift without ... Pulit-Penaloza J, Belser JA, Brock N, Kieran TJ, P. Risk assessment of avian influenza A(H5N5) virus from the first human case using the ferret model. J Virol 0:e00856-26. Abstract
submitted by kickingbird at 4 days ago from J Virol 0:e00856-26 (via https://journals.asm.org/doi/10.1128/jvi.00856-26)
The incursion of Eurasian-origin genotype A6 A(H5N5) virus into North America expanded the genetic diversity among North American highly pathogenic avian influenza viruses and heightened concern about ... Hautefeuille C, Mu?oz F, Dauphin G, Peyre M, Gouta. Risk assessment of transmission of highly pathogenic avian influenza H5 viruses into French broiler and layer farms from other poultry sectors. Prev Vet Med. 2026 Aug 1;256:106981. Abstract
submitted by kickingbird at 5 days ago from Prev Vet Med. 2026 Aug 1;256:106981 (via https://www.sciencedirect.com/science/article/pii/S016758772)
Highly pathogenic avian influenza (HPAI) H5 viruses are a major threat to the French poultry sector. All sectors are affected and virus transmission between sectors has been reported. The objective of ... Thirion M, Stelfox AJ, Chenavier F, Chomat H, Isel. Nucleocapsid-like cryoEM structure of influenza B virus. PLoS Pathog. 2026 Aug 10;22(8):e101444. Abstract
submitted by kickingbird at 5 days ago from PLoS Pathog. 2026 Aug 10;22(8):e101444 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza viruses belong to the Orthomyxoviridae family, they are categorized into four types: A, B, C, and D. Influenza B viruses co-circulate annually with influenza A strains during seasonal flu epidemics ... Ríos Carrasco M, Guerreiro Cabana MF, Kovács E, Du. Acquisition of specific human respiratory tract binding by 2.3.4.4b H5N1 hemagglutinins requires multiple mutations. J Virol. 2026 Aug 10:e0106526. Abstract
submitted by kickingbird at 5 days ago from J Virol. 2026 Aug 10:e0106526 (via https://journals.asm.org/doi/10.1128/jvi.01065-26)
It has been suggested that the hemagglutinin of the human-infecting cattle-derived 2.3.4.4b virus A/Texas/34 H5N1 (H5TX) requires only one mutation, namely Q226L, to switch from binding avian-type to human-type ... Rytlewski K, Dunn A, O’Halloran A, et al. Effectiveness of Oseltamivir in Hospitalized Children With Laboratory-Confirmed Influenza, 2014-2023. JAMA Pediatr. Abstract
submitted by kickingbird at 5 days ago from JAMA Pediatr (via https://jamanetwork.com/journals/jamapediatrics/fullarticle/)
Importance: National organizations recommend antiviral treatment for hospitalized children with influenza; however, use in this setting has recently declined. Studies of oseltamivir effectiveness in children ... Martínez-Guevara J, Lai T, Mishra M et al. Immunodominance hierarchy of influenza A haemagglutinin antigenic sites: an observational cohort study across distinct exposure histories. eBioMedicine, 2026; 131. Abstract
submitted by kickingbird at 6 days ago from eBioMedicine, 2026; 131 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: Antibody responses to influenza A viruses are strongly focused on immunodominant antigenic sites within the haemagglutinin (HA) head domain. Although immunodominance hierarchies have been described ... Neumann, G., Cowling, B.J., Chen, H. et al. Influenza. Nat Rev Dis Primers 12, 51 (2026). Abstract
submitted by kickingbird at 6 days ago from Nat Rev Dis Primers 12, 51 (2026) (via https://www.nature.com/articles/s41572-026-00727-5)
Influenza A and B viruses are considerable public health threats. Annual seasonal epidemics are driven by antigenic drift and cause an estimated 3–5 million severe cases and 290,000–650,000 deaths annually. ... Xuan Zuo, etc.,al. Seasonal forcing and contact heterogeneity generate recurrent influenza dynamics in age-structured population. Chaos, Solitons & Fractals. Abstract
submitted by kickingbird at 7 days ago from Chaos, Solitons & Fractals (via https://www.sciencedirect.com/science/article/abs/pii/S09600)
Influenza transmission is shaped by temporary immunity, age-structured contact heterogeneity, and seasonal variation in transmissibility, generating persistent circulation, heterogeneous demographic burden, ... Alexander M.P. Byrne, etc.,al. Impact of prior low-pathogenicity avian influenza H7N7 exposure on susceptibility and protection against homologous high-pathogenicity avian influenza H7N7 challenge in chickens. Virology. Abstract
submitted by kickingbird at 7 days ago from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Circumstances driving the transition from low-pathogenicity to high-pathogenicity avian influenza viruses (LPAIVs to HPAIVs) remain poorly understood. In July 2015, a UK layer outbreak revealed circulation ... Ahmed M. Elsayed, etc.,al. [preprint]A One-Shot Multivalent Live-Attenuated Candidate Influenza Vaccine against Divergent Zoonotic H5N1 Clades. https://doi.org/10.64898/2026.08.02.742385. Abstract
submitted by kickingbird at 7 days ago from https://doi.org/10.64898/2026.08.02.742385 (via https://www.biorxiv.org/content/10.64898/2026.08.02.742385v1)
The continued emergence of genetically diverse high pathogenicity avian influenza (HPAI) H5N1 viruses with zoonotic potential highlights the urgent need for developing vaccines capable of providing broad ... 7067 items, 20/Page, Page[1/354][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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