Yang L, Zhu W, Li X, Chen M, et al. Genesis and Spread of Newly Emerged Highly Pathogenic H7N9 Avian Viruses in Mainland China. J Virol 2017;91. Abstract
submitted by kickingbird at 5 days ago from J Virol 2017;91 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28956760/)
The novel low-pathogenic avian influenza A H7N9 viruses (LPAI H7N9 viruses) have been a threat to public health since their emergence in 2013 because of the high rates of mortality and morbidity that they ...
Iwatsuki-Horimoto K, Nakajima N, Ichiko Y, Sakai-T. Syrian hamster as an animal model for the study of human influenza virus infection. J Virol 2017 Dec 6. Abstract
submitted by kickingbird at 5 days ago from J Virol 2017 Dec 6 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29212926/)
Ferrets and mice are frequently used as animal models for influenza research. However, ferrets are demanding in terms of housing space and handling, whereas mice are not naturally susceptible to infection ...
Zhong G, Le MQ, Lopes TJS, Halfmann P, et al. Mutations in the PA Protein of Avian H5N1 Influenza Viruses Affect Polymerase Activity and Mouse Virule. J Virol 2017 Dec 6. Abstract
submitted by kickingbird at 5 days ago from J Virol 2017 Dec 6 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29212927/)
To study the influenza viral determinants of pathogenicity, we characterized two highly pathogenic avian H5N1 influenza viruses isolated in Vietnam in 2012 (A/duck/Vietnam/QT1480/2012; QT1480) and 2013 ...
Xiao J, Rijal P, Schimanski L, Tharkeshwar AK, et. Characterization of an influenza virus pseudotyped with Ebolavirus glycoprotein. J Virol 2017 Dec 6. Abstract
submitted by kickingbird at 5 days ago from J Virol 2017 Dec 6 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29212933/)
We have produced a new Ebola virus pseudotype: E-S-FLU, which can be handled in biosafety level-1/2 containment for laboratory analysis. E-S-FLU is a single cycle influenza virus coated with Ebolavirus ...
Chen C, Liu L, Xiao Y, Cui S, et al.. Structural insight into a human neutralizing antibody against influenza virus H7N9. J Virol 2017 Dec 6. Abstract
submitted by kickingbird at 5 days ago from J Virol 2017 Dec 6 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29212936/)
Since its first emergence in East China in early 2013, many cases of avian influenza A H7N9 have been reported. The disease has extended to 22 provinces in mainland China and some surrounding areas. Strategies ...
Makvandi-Nejad S, Laurenson-Schafer H, Wang L, Wel. Lack of Truncated IFITM3 Transcripts in Cells Homozygous for the rs12252-C Variant That is Associated With Severe Influenza Infection. J Infect Dis 2017 Nov 30. Abstract
submitted by kickingbird at 5 days ago from J Infect Dis 2017 Nov 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29202190/)
Interferon-induced transmembrane 3 (IFITM3) is known to restrict the entry of a range of enveloped viruses. The single nucleotide polymorphism rs12252-C within IFITM3 has been shown to be associated with ...
Qi X, Zhang H, Xue T, Yang B, et al. Down-regulation of cellular protein heme oxygenase-1 inhibits proliferation of avian influenza virus H9N2 in chicken oviduct epithelial cells. J Gen Virol 2017 Dec 8. Abstract
submitted by kickingbird at 5 days ago from J Gen Virol 2017 Dec 8 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29219807/)
The pathogenesis of H9N2 subtype avian influenza virus (AIV) infection in hens is often related to oviduct tissue damage. Our previous study suggested that H9N2 AIV induces cellular apoptosis by activating ...
C Li, etc.,al. Genetic evolution of influenza H9N2 viruses isolated from various hosts in China from 1994 to 2013. Emerging Microbes & Infections (2017). Abstract
submitted by kickingbird at 6 days ago from Emerging Microbes & Infections (2017) (via http://www.nature.com/articles/emi201794)
Influenza H9N2 subtype viruses and their reassortants (such as H7N9) are posing increasing threats to birds and humans in China. During 2009–2013, multiple novel subtype viruses with H9N2 original genes ...
J Chen, etc.,al. Long term outcomes in survivors of epidemic Influenza A (H7N9) virus infection. Scientific Reports 7, Article number: 17275 (2017). Abstract
submitted by kickingbird at 6 days ago from Scientific Reports 7, Article number: 17275 (2017) (via https://www.nature.com/articles/s41598-017-17497-6)
Patients who survive influenza A (H7N9) virus infection are at risk of physical and psychological complications of lung injury and multi-organ dysfunction. However, there were no prospectively individualized ...
Iskandar VI, Sasaki Y, Yoshino N, Abubakar RZR, et. Optimization of trypsins for influenza A/H1N1 virus replication in MDCK SI-6 cells, a novel MDCK cell line. J Virol Methods 2017 Nov 16. Abstract
submitted by kickingbird at Nov, 26, 2017 from J Virol Methods 2017 Nov 16 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29155214/)
A cell-based vaccine production method for influenza virus may be an effective and more rapid alternative to egg-based systems. For high-yield virus production, the effect of bovine, porcine, fungal, and ...
Su WC, Yu WY, Huang SH, Lai MMC, et al. Ubiquitination of the Cytoplasmic Domain of Influenza A Virus M2 Protein is Crucial for Production of Infectious Virus Particles. J Virol 2017 Nov 22. Abstract
submitted by kickingbird at Nov, 26, 2017 from J Virol 2017 Nov 22 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29167343/)
Virus replication is mediated by interactions between virus and host. Here, we demonstrate that influenza A virus membrane protein 2 (M2) can be ubiquitinated. The lysine residue at position 78, which ...
Wan H, Qi L, Gao J, Couzens LK, et al. Comparison of the Efficacy of N9 Neuraminidase-specific Monoclonal Antibodies against Influenza A(H7N9) Virus Infection. J Virol 2017 Nov 22. Abstract
submitted by kickingbird at Nov, 26, 2017 from J Virol 2017 Nov 22 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29167344/)
The fifth wave of A(H7N9) virus infection in China from 2016 to 2017 caused great concern due to the large number of individuals infected, the isolation of drug-resistant viruses and emergence of highly ...
Nam JH, Song EJ, Song D, Espano E, et al. Molecular and phylogenetic analyses of influenza B viruses isolated from pediatric inpatients in South Korea during the 2011-2012 winter season. J Gen Virol 2017 Nov 23. Abstract
submitted by kickingbird at Nov, 26, 2017 from J Gen Virol 2017 Nov 23 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29168676/)
Influenza B virus remains a major cause of respiratory diseases worldwide. Because of limited epidemiological and genetic data, the local and global transmission patterns of influenza B virus are not fully ...
Adeola OA, Olugasa BO, Emikpe BO. Molecular detection of influenza A(H1N1)pdm09 viruses with M genes from human pandemic strains among Nigerian pigs, 2013-2015: implications and associated risk factors. Epidemiol Infect 2017 Nov 23. Abstract
submitted by kickingbird at Nov, 26, 2017 from Epidemiol Infect 2017 Nov 23 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29166978/)
In the post-pandemic period, influenza A(H1N1)pdm09 virus has been detected in swine populations in different parts of the world. This study was conducted to determine the presence and spatial patterns ...
Wu H, Yang F, Lu R, Xu L, et al. Isolation and molecular characterization of an H5N1 swine influenza virus in China in 2015. Arch Virol 2017 Nov 21. Abstract
submitted by kickingbird at Nov, 26, 2017 from Arch Virol 2017 Nov 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29164401/)
In 2015, an H5N1 influenza virus was isolated from a pig in Zhejiang Province, Eastern China. This strain was characterized by whole-genome sequencing with subsequent phylogenetic analysis. Phylogenetic ...
N. Wang et al.. Avian Influenza (H7N9) Viruses Co-circulating among Chickens, Southern China. EID Vol 23, Dec 2017. Abstract
submitted by kickingbird at Nov, 18, 2017 from EID Vol 23, Dec 2017 (via https://wwwnc.cdc.gov/eid/article/23/12/17-0782_article)
In April 2017, three avian influenza (H7N9) viruses were isolated from chickens in southern China. Each virus had different insertion points in the cleavage site of the hemagglutinin protein compared to ...
Yu Z, Cheng K, Sun W, Zhang X, et al. Multiple adaptive amino acid substitutions increase the virulence of a wild waterfowl-origin reassortant H5N8 avian influenza virus in mice. Virus Res 2017 Nov 4. Abstract
submitted by kickingbird at Nov, 13, 2017 from Virus Res 2017 Nov 4 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29113821/)
A novel H5N8 highly pathogenic avian influenza virus (HPAIV) caused poultry outbreaks in the Republic of Korea in 2014. The novel H5N8 HPAIV has spread to Asia, Europe, and North America and caused great ...
Ni Y, Guo J, Turner D, Tizard I, et al. Development of a novel dual-domain nanoparticle antigen construct for universal influenza vaccine. Vaccine 2017 Oct 25. Abstract
submitted by kickingbird at Nov, 13, 2017 from Vaccine 2017 Oct 25 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29102171/)
A highly effective antigen construct for presenting conserved antigen domains is essential to the development of a universal influenza vaccine. We have developed a novel dual-domain nanoparticle fusion ...
Zost SJ, Parkhouse K, Gumina ME, Kim K, et al. Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains. Proc Natl Acad Sci U S A 2017 Nov 6. Abstract
submitted by kickingbird at Nov, 13, 2017 from Proc Natl Acad Sci U S A 2017 Nov 6 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29109276/)
H3N2 viruses continuously acquire mutations in the hemagglutinin (HA) glycoprotein that abrogate binding of human antibodies. During the 2014-2015 influenza season, clade 3C.2a H3N2 viruses possessing ...
Kok TW, Costabile M, Tannock GA, Li P, et al. Colocalization of intracellular specific IgA (icIgA) with influenza virus in patients´ nasopharyngeal aspirate cells. J Virol Methods 2017 Nov 1. Abstract
submitted by kickingbird at Nov, 13, 2017 from J Virol Methods 2017 Nov 1 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29102516/)
Inhibition of viral replication by icIgA antibodies has only been observed with in vitro studies using epithelial cell lines in transwell cultures. This effect appears to involve an interaction between ...
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