Hill NJ, Bishop MA, Trov?o NS, Ineson KM, Schaefer. Ecological divergence of wild birds drives avian influenza spillover and global spread. PLoS Pathog. 2022 May 19;18(5):e1010062. Abstract
submitted by kickingbird at 12 hours ago from PLoS Pathog. 2022 May 19;18(5):e1010062 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The diversity of influenza A viruses (IAV) is primarily hosted by two highly divergent avian orders: Anseriformes (ducks, swans and geese) and Charadriiformes (gulls, terns and shorebirds). Studies of ...
Yang F, Zhu L, Liu F, Cheng L, Yao H, Wu N, Wu H,. Generation and characterization of monoclonal antibodies against the hemagglutinin of H3N2 influenza A viruses. Virus Res. 2022 May 17:198815. Abstract
submitted by kickingbird at 12 hours ago from Virus Res. 2022 May 17:198815 (via https://www.sciencedirect.com/science/article/abs/pii/S01681)
Seasonal influenza viruses are highly contagious, leading to 290,000-650,000 mortalities every year globally. Among the influenza viruses, influenza A virus (H3N2) has attracted much attention due to its ...
Zhao C, Guo J, Zeng X, Shi J, Deng G, Zhang Y, Wan. Novel H7N7 avian influenza viruses detected in migratory wild birds in eastern China between 2018 and 2020. Microbes Infect. 2022 May 14:105013. Abstract
submitted by kickingbird at 4 days ago from Microbes Infect. 2022 May 14:105013 (via https://www.sciencedirect.com/science/article/pii/S128645792)
Wild birds are the natural reservoirs of avian influenza viruses, and surveillance and assessment of these viruses in wild birds provide valuable information for early warning and control of animal diseases. ...
Wang Q, Wang J, Xu Y, Li Z, Wang B, Li Y. The Interaction of Influenza A NS1 and Cellular TRBP Protein Modulates the Function of RNA Interference Machinery. Front Microbiol. 2022 Apr 26;13:859420. Abstract
submitted by kickingbird at 5 days ago from Front Microbiol. 2022 Apr 26;13:859420 (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087287/)
Influenza A virus (IAV), one of the most prevalent respiratory diseases, causes pandemics around the world. The multifunctional non-structural protein 1 (NS1) of IAV is a viral antagonist that suppresses ...
Schaaf KR, Buggs CJ, Putz ND, Langouet-Astrie CJ,. Influenza A Virus Causes Shedding of the Alveolar Epithelial Glycocalyx through Activation of Sheddases. FASEB J. 2022 May;36 Suppl 1. Abstract
submitted by kickingbird at 5 days ago from FASEB J. 2022 May;36 Suppl 1 (via https://faseb.onlinelibrary.wiley.com/doi/10.1096/fasebj.202)
Objective: The healthy alveolar epithelium is protected by a heparan sulfate rich, glycosaminoglycan layer called the epithelial glycocalyx. Our group found that the epithelial glycocalyx is shed in patients ...
LE KT, Isoda N, Nguyen LT, Chu DH, Nguyen LV, Phan. Risk profile of low pathogenicity avian influenza virus infections in farms in southern Vietnam. J Vet Med Sci. 2022 May 13. Abstract
submitted by kickingbird at 5 days ago from J Vet Med Sci. 2022 May 13 (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_22)
The impact of low pathogenicity avian influenza (LPAI) has been confirmed mainly in farms. Unlike apparent losses caused by the high pathogenicity avian influenza (HPAI), the LPAI impact has been hardly ...
Zhu F, Teng Z, Zhou X, Xu R, Bing X, Shi L, Guo N,. H1N1 Influenza Virus-Infected Nasal Mucosal Epithelial Progenitor Cells Promote Dendritic Cell Recruitment and Maturation. Front Immunol. 2022 Apr 28;13:879575. Abstract
submitted by kickingbird at 5 days ago from Front Immunol. 2022 Apr 28;13:879575 (via https://www.frontiersin.org/articles/10.3389/fimmu.2022.8795)
The barrier function of nasal mucosal epithelial cells plays an irreplaceable role in the spread and expansion of viruses in the body. This study found that influenza A virus H1N1 could induce apoptosis ...
Vandoorn E, Stadejek W, Parys A, Chepkwony S, Chie. Pathobiology of an NS1-Truncated H3N2 Swine Influenza Virus Strain in Pigs. J Virol. 2022 May 12:e0051922. Abstract
submitted by kickingbird at 8 days ago from J Virol. 2022 May 12:e0051922 (via https://journals.asm.org/doi/10.1128/jvi.00519-22)
Virus strains in the live attenuated influenza vaccine (LAIV) for swine in the United States that was on the market until 2020 encode a truncated nonstructural protein 1 of 126 amino acids (NS1del126). ...
Kuroda M, Usui T, Shibata C, Nishigaki H, Yamaguch. Possible bidirectional human-swine and subsequent human-human transmission of influenza virus A(H1N1)/2009 in Japan. Zoonoses Public Health. 2022 May 10. Abstract
submitted by kickingbird at 11 days ago from Zoonoses Public Health. 2022 May 10 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.12960)
In 2019, sows at a swine farm in Japan showed influenza-like illness (ILI) shortly after contact with an employee that exhibited ILI. Subsequently, a veterinarian became sick shortly after examining the ...
Wille M, Grillo V, Ban de Gouvea Pedroso S, Burges. Australia as a global sink for the genetic diversity of avian influenza A virus. PLoS Pathog. 2022 May 10;18(5):e1010150. Abstract
submitted by kickingbird at 12 days ago from PLoS Pathog. 2022 May 10;18(5):e1010150 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Most of our understanding of the ecology and evolution of avian influenza A virus (AIV) in wild birds is derived from studies conducted in the northern hemisphere on waterfowl, with a substantial bias ...
Pulit-Penaloza JA, Brock N, Jones J, Belser JA, Ja. Pathogenesis and Transmission of Human Seasonal and Swine-origin A(H1) Influenza Viruses in the Ferret Model. Emerg Microbes Infect. 2022 May 10:1-20. Abstract
submitted by kickingbird at 12 days ago from Emerg Microbes Infect. 2022 May 10:1-20 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2022.2)
Influenza A viruses (IAVs) in the swine reservoir constantly evolve, resulting in expanding genetic and antigenic diversity of strains that occasionally cause infections in humans and pose threat of emerging ...
Molini U, Curini V, Jacobs E, Tongo E, Berjaoui S,. First influenza D virus full-genome sequence retrieved from livestock in Namibia, Africa. Acta Trop. 2022 May 7:106482. Abstract
submitted by kickingbird at 12 days ago from Acta Trop. 2022 May 7:106482 (via https://www.sciencedirect.com/science/article/pii/S0001706X2)
Influenza D virus (IDV) was first isolated in 2011 in the USA and has since been shown to circulate in cattle, pigs, sheep, wild boar, and camels. In Africa, there is limited data on the epidemiology of ...
Patrono LV, Vrancken B, Budt M, Düx A, Lequime S,. Archival influenza virus genomes from Europe reveal genomic variability during the 1918 pandemic. Nat Commun. 2022 May 10;13(1):2314. Abstract
submitted by kickingbird at 12 days ago from Nat Commun. 2022 May 10;13(1):2314 (via https://www.nature.com/articles/s41467-022-29614-9)
The 1918 influenza pandemic was the deadliest respiratory pandemic of the 20th century and determined the genomic make-up of subsequent human influenza A viruses (IAV). Here, we analyze both the first ...
Ryt-Hansen P, Nielsen HG, S?rensen SS, Larsen I, K. The role of gilts in transmission dynamics of swine influenza virus and impacts of vaccination strategies and quarantine management. Porcine Health Manag. 2022 May 5;8(1):19. Abstract
submitted by kickingbird at May, 7, 2022 from Porcine Health Manag. 2022 May 5;8(1):19 (via https://porcinehealthmanagement.biomedcentral.com/articles/1)
Background: Along with an expanding global swine production, the commercial housing and management of swine herds, provide an optimal environment for constant circulation of swine influenza virus (swIAV), ...
Van Poelvoorde L, Vanneste K, De Keersmaecker SCJ,. Whole-Genome Sequence Approach and Phylogenomic Stratification Improve the Association Analysis of Mutations With Patient Data in Influenza Surveillance. Front Microbiol. 2022 Apr 19;13:809887. Abstract
submitted by kickingbird at May, 7, 2022 from Front Microbiol. 2022 Apr 19;13:809887 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.8098)
Each year, seasonal influenza results in high mortality and morbidity. The current classification of circulating influenza viruses is mainly focused on the hemagglutinin gene. Whole-genome sequencing (WGS) ...
Zhang Q, Zhang X, Lei X, Wang H, Jiang J, Wang Y,. Influenza A virus NS1 protein hijacks YAP/TAZ to suppress TLR3-mediated innate immune response. PLoS Pathog. 2022 May 3;18(5):e1010505. Abstract
submitted by kickingbird at May, 5, 2022 from PLoS Pathog. 2022 May 3;18(5):e1010505 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The Hippo signaling pathway, which is historically considered as a dominator of organ development and homeostasis has recently been implicated as an immune regulator. However, its role in host defense ...
King J, Harder T, Globig A, Stacker L, Günther A,. Highly pathogenic avian influenza virus incursions of subtype H5N8, H5N5, H5N1, H5N4, and H5N3 in Germany during 2020-21. Virus Evol. 2022 Apr 13;8(1):veac035. Abstract
submitted by kickingbird at Apr, 30, 2022 from Virus Evol. 2022 Apr 13;8(1):veac035 (via https://academic.oup.com/ve/article/8/1/veac035/6568266)
From October 2020 to July 2021, five different subtypes (H5N8, H5N5, H5N1, H5N4, and H5N3) and seven genotypes of highly pathogenic avian influenza viruses (HPAIV) belonging to clade 126.96.36.199b were detected ...
Yao Q, Mai W, Lian Y, Zhang M, Yao Q, Huang C, Ge. Emergence and Evolution of Novel Canine-Avian Reassortant H3N2 Influenza A Viruses in Duck in Leizhou Peninsula, China. Front Microbiol. 2022 Apr 5;13:857800. Abstract
submitted by kickingbird at Apr, 30, 2022 from Front Microbiol. 2022 Apr 5;13:857800 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.8578)
Avian-to-mammal transmission and mammalian adaptation of avian influenza virus (AIV) are threats to public health and of great concern. The H3 subtype of influenza virus has low pathogenicity and is widely ...
Chauhan RP, Gordon ML. An overview of influenza A virus genes, protein functions, and replication cycle highlighting important updates. Virus Genes. 2022 Apr 26. Abstract
submitted by kickingbird at Apr, 27, 2022 from Virus Genes. 2022 Apr 26 (via https://link.springer.com/article/10.1007/s11262-022-01904-w)
The recent research findings on influenza A virus (IAV) genome biology prompted us to present a comprehensive overview of IAV genes, protein functions, and replication cycle. The eight gene segments of ...
Feng H, Yi R, Wu S, Wang G, Sun R, Lin L, Zhu S, N. KAP1 Positively Modulates Influenza A Virus Replication by Interacting with PB2 and NS1 Proteins in Human Lung Epithelial Cells. Viruses. 2022 Mar 26;14(4):689. Abstract
submitted by kickingbird at Apr, 24, 2022 from Viruses. 2022 Mar 26;14(4):689 (via https://www.mdpi.com/1999-4915/14/4/689)
Influenza virus only encodes a dozen of viral proteins, which need to use host machinery to complete the viral life cycle. Previously, KAP1 was identified as one host protein that potentially interacts ...
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