Carrique L, Fan H, Walker AP, Keown JR, Sharps J,. Host ANP32A mediates the assembly of the influenza virus replicase. Nature. 2020 Nov 18. Abstract
submitted by kickingbird at 2 days ago from Nature. 2020 Nov 18 (via https://www.nature.com/articles/s41586-020-2927-z)
Aquatic birds represent a vast reservoir from which new pandemic influenza A viruses can emerge1. Influenza viruses contain a negative-sense segmented RNA genome that is transcribed and replicated by the ...
Chung DH, Gomez DR, Vargas JM, Amador BL, Torchett. Low Pathogenicity Avian Influenza (H5N2) Viruses, Dominican Republic. Emerg Infect Dis. 2020 Dec;26(12):3094-3096. Abstract
submitted by kickingbird at 2 days ago from Emerg Infect Dis. 2020 Dec;26(12):3094-3096 (via https://wwwnc.cdc.gov/eid/article/26/12/20-0268_article)
Low pathogenicity avian influenza (H5N2) virus was detected in poultry in the Dominican Republic in 2007 and re-emerged in 2017. Whole-genome sequencing and phylogenetic analysis show introduction of an ...
Bravo-Vasquez N, Yao J, Jimenez-Bluhm P, Meliopoul. Equine-Like H3 Avian Influenza Viruses in Wild Birds, Chile. Emerg Infect Dis. 2020 Dec;26(12):2887-2898. Abstract
submitted by kickingbird at 2 days ago from Emerg Infect Dis. 2020 Dec;26(12):2887-2898 (via https://wwwnc.cdc.gov/eid/article/26/12/20-2063_article)
Since their discovery in the United States in 1963, outbreaks of infection with equine influenza virus (H3N8) have been associated with serious respiratory disease in horses worldwide. Genomic analysis ...
Jiang Y, Ye Z, Chen D, Shu Y. Dual influenza and pneumococcal vaccination was associated with lower short-term risks of all-cause and acute respiratory hospitalizations among the elderly in Shenzhen, China: a retrospective cohort. Emerg Microbes Infect . 2020 Nov 20;1-0. Abstract
submitted by kickingbird at 2 days ago from Emerg Microbes Infect . 2020 Nov 20;1-0 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2020.1)
Objectives The present study aimed to evaluate the real-world effectiveness of receiving both influenza and pneumococcal vaccines among Chinese elderly, the evidence on which has been sparse by far. Methods ...
Liu Y, Wang Y, Liu B, Cong X, Ji Y, Guo X, Gao Y. Phylogenetic analysis and clinical characteristics of the co-occurring mutations in HA and NA genes of influenza A(H1N1)pdm09 viruses during 2015-2017 in Beijing, China. Virol J. 2020 Nov 19;17(1):182.. Abstract
submitted by kickingbird at 2 days ago from Virol J. 2020 Nov 19;17(1):182. (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Influenza A(H1N1)pdm09 viruses have undergone rapid evolution, and in recent years the complementary and antagonistic effects of HA and NA have gathered more attentions; however, the effects ...
Melidou A, Pereyaslov D, Hungnes O, Prosenc K, Alm. Virological surveillance of influenza viruses in the WHO European Region in 2019/20 - impact of the COVID-19 pandemic. Euro Surveill. 2020 Nov;25(46). Abstract
submitted by kickingbird at 2 days ago from Euro Surveill. 2020 Nov;25(46) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
The COVID-19 pandemic negatively impacted the 2019/20 WHO European Region influenza surveillance. Compared with previous 4-year averages, antigenic and genetic characterisations decreased by 17% (3,140 ...
Yu J, Li F, Wang D. The first decade of research advances in influenza D virus. J Gen Virol. 2020 Nov 19. Abstract
submitted by kickingbird at 2 days ago from J Gen Virol. 2020 Nov 19 (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
From its initial isolation in the USA in 2011 to the present, influenza D virus (IDV) has been detected in cattle and swine populations worldwide. IDV has exceptional thermal and acid stability and a broad ...
Nasamran C, Janetanakit T, Chiyawong S, Boonyapisi. Persistence of pdm2009-H1N1 internal genes of swine influenza in pigs, Thailand. Sci Rep. 2020 Nov 16;10(1):19847. Abstract
submitted by kickingbird at 5 days ago from Sci Rep. 2020 Nov 16;10(1):19847 (via https://www.nature.com/articles/s41598-020-76771-2)
Swine influenza is one of the important zoonotic diseases of pigs. We conducted a longitudinal survey of swine influenza A viruses (S-IAV) circulating in a pig farm with history of endemic S-IAV infection ...
Chastagner A, Hervé S, Quéguiner S, Hirchaud E, Lu. Genetic and Antigenic Evolution of European Swine Influenza A Viruses of HA-1C (Avian-Like) and HA-1B (Human-Like) Lineages in France from 2000 to 2018. Viruses. 2020 Nov 13;12(11):E1304. Abstract
submitted by kickingbird at 5 days ago from Viruses. 2020 Nov 13;12(11):E1304 (via https://www.mdpi.com/1999-4915/12/11/1304)
This study evaluated the genetic and antigenic evolution of swine influenza A viruses (swIAV) of the two main enzootic H1 lineages, i.e., HA-1C (H1av) and -1B (H1hu), circulating in France between 2000 ...
Amal EB, Saadi N, Asma F, Moncef B, Ouafae FF. Characterization and Phylogenetic Analysis of the Hemagglutinin Gene in H9 Influenza Viruses from Chickens in Morocco from 2017 to 2019. Avian Dis. 2020 Sep 1;64(3):310-314. Abstract
submitted by kickingbird at 5 days ago from Avian Dis. 2020 Sep 1;64(3):310-314 (via https://bioone.org/journals/avian-diseases/volume-64/issue-3)
Since the early 2000s, the avian influenza virus (AIV) subtype H9N2 has been widely circulating in North African countries, including Libya, Tunisia, and Egypt. For unknown reasons, H9N2 was not detected ...
Abhijeet A Bakre, et al. Molecular epidemiology and glycomics of swine influenza viruses circulating in commercial swine farms in the southeastern and midwest United States. Vet Microbiol . 2020 Oct 31;251:108914. Abstract
submitted by kickingbird at 8 days ago from Vet Microbiol . 2020 Oct 31;251:108914 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Tracking the genetic diversity and spread of swine influenza viruses (SIVs) in commercial swine farms is central for control and to reduce the potential emergence of SIV reassortants. We analyzed the diversity ...
Carre?o JM, McDonald JU, Hurst T, Rigsby P, Atkins. Development and Assessment of a Pooled Serum as Candidate Standard to Measure Influenza A Virus Group 1 Hemagglutinin Stalk-Reactive Antibodies. Vaccines (Basel). 2020 Nov 9;8(4):E666. Abstract
submitted by kickingbird at 8 days ago from Vaccines (Basel). 2020 Nov 9;8(4):E666 (via https://www.mdpi.com/2076-393X/8/4/666)
The stalk domain of the hemagglutinin has been identified as a target for induction of protective antibody responses due to its high degree of conservation among numerous influenza subtypes and strains. ...
Tian X, Landreth S, Lu Y, Pandey K, Zhou Y. A Replication-Defective Influenza Virus Harboring H5 and H7 Hemagglutinins Provides Protection against H5N1 and H7N9 Infection in Mice. J Virol. 2020 Nov 11:JVI.02154-20. Abstract
submitted by kickingbird at 11 days ago from J Virol. 2020 Nov 11:JVI.02154-20 (via https://jvi.asm.org/content/early/2020/11/06/JVI.02154-20)
The recent highly pathogenic avian influenza (HPAI) H5N1 and H7N9 viruses have caused hundreds of human infections with high mortality rates. Although H5N1 and H7N9 viruses have been mainly limited to ...
Bao D, Xue R, Zhang M, Lu C, Ma T, Ren C, Zhang T,. N-linked glycosylation plays an important role in budding of NA protein and virulence of influenza viruses. J Virol. 2020 Nov 11:JVI.02042-20. Abstract
submitted by kickingbird at 11 days ago from J Virol. 2020 Nov 11:JVI.02042-20 (via https://jvi.asm.org/content/early/2020/11/06/JVI.02042-20)
Neuraminidase (NA) has multiple functions in the life cycle of influenza virus, especially in the late stage of virus replication. Both of Hemagglutinin (HA) and NA are highly glycosylated proteins. N-linked ...
Speake HA, Pereira G, Regan AK. Risk of adverse maternal and foetal outcomes associated with inactivated influenza vaccination in first trimester of pregnancy. Paediatr Perinat Epidemiol. 2020 Nov 5. Abstract
submitted by kickingbird at 15 days ago from Paediatr Perinat Epidemiol. 2020 Nov 5 (via https://onlinelibrary.wiley.com/doi/10.1111/ppe.12715)
Background: In many countries, influenza vaccination is routinely recommended during any stage of pregnancy, yet uptake remains low, particularly in the first trimester. This is thought to be due to maternal ...
Toy R, Keenum MC, Pradhan P, Phang K, Chen P, Chuk. TLR7 and RIG-I dual-adjuvant loaded nanoparticles drive broadened and synergistic responses in dendritic cells in vitro and generate unique cellular immune responses in influenza vaccinatio. J Control Release. 2020 Nov 4:S0168-3659(20)30641-. Abstract
submitted by kickingbird at 15 days ago from J Control Release. 2020 Nov 4:S0168-3659(20)30641- (via https://www.sciencedirect.com/science/article/abs/pii/S01683)
Although the existing flu vaccines elicit strong antigen-specific antibody responses, they fail to provide effective, long term protection - partly due to the absence of robust cellular memory immunity. ...
Zaraket H, Hurt AC, Clinch B, Barr I, Lee N. Burden of influenza B virus infection and considerations for clinical management. Antiviral Res. 2020 Nov 4:104970. Abstract
submitted by kickingbird at 15 days ago from Antiviral Res. 2020 Nov 4:104970 (via https://www.sciencedirect.com/science/article/abs/pii/S01663)
Influenza B viruses cause significant morbidity and mortality, particularly in children, but the awareness of their impact is often less than influenza A viruses partly due to their lack of pandemic potential. ...
Vagima Y, Gur D, Erez N, Achdout H, Aftalion M, Le. Influenza virus infection augments susceptibility to respiratory Yersinia pestis exposure and impacts the efficacy of antiplague antibiotic treatments. Sci Rep. 2020 Nov 5;10(1):19116. Abstract
submitted by kickingbird at Nov, 8, 2020 from Sci Rep. 2020 Nov 5;10(1):19116 (via https://www.nature.com/articles/s41598-020-75840-w)
Various respiratory viral infections in general and seasonal influenza in particular may increase the susceptibility to bacterial infections. Plague caused by Yersinia pestis endangers large populations ...
Timofeeva TA, Rudneva IA, Sadykova GK, Lomakina NF. Variability of nonpathogenic influenza virus H5N3 under immune pressure. Acta Virol. 2020 Nov 5. Abstract
submitted by kickingbird at Nov, 7, 2020 from Acta Virol. 2020 Nov 5 (via https://pubmed.ncbi.nlm.nih.gov/33151742/)
Mutations arising in influenza viruses that have undergone immune pressure may promote a successful spread of mutants in nature. In order to evaluate the variability of nonpathogenic influenza virus A/duck/Moscow/4182-C/2010(H5N3) ...
Igboh LS, McMorrow M, Tempia S, Emukule GO, Talla. Influenza surveillance capacity improvements in Africa during 2011-2017. Influenza Other Respir Viruses. 2020 Nov 4. Abstract
submitted by kickingbird at Nov, 7, 2020 from Influenza Other Respir Viruses. 2020 Nov 4 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12818)
Background: Influenza surveillance helps time prevention and control interventions especially where complex seasonal patterns exist. We assessed influenza surveillance sustainability in Africa where influenza ...
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