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2024-3-29 15:48:19
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Meng B, Wang Q, Leng H, Ren C, Feng C, Guo W, Feng. Evolutionary Events Promoted Polymerase Activity of H13N8 Avian Influenza Virus. Viruses. 2024 Feb 21;16(3):329.  Abstract  
submitted by kickingbird at 9 hours ago from Viruses. 2024 Feb 21;16(3):329 (via https://www.mdpi.com/1999-4915/16/3/329)
Wild birds are considered to be the natural reservoir hosts of avian influenza viruses (AIVs). Wild bird-origin AIVs may spill over into new hosts and overcome species barriers after evolutionary adaptation. ...

Lin S, Zhang Y, Yang J, Yang L, Li X, Bo H, Liu J,. Cross-Species Transmission Potential of H4 Avian Influenza Viruses in China: Epidemiological and Evolutionary Study. Viruses. 2024 Feb 24;16(3):353.  Abstract  
submitted by kickingbird at 9 hours ago from Viruses. 2024 Feb 24;16(3):353 (via https://www.mdpi.com/1999-4915/16/3/353)
H4 avian influenza viruses (AIVs) have been widely detected in live poultry markets in China. However, the potential public health impact of H4 AIVs remains largely uncertain. Here, we fully analyzed the ...

Tang S, Han B, Su C, Li H, Zhao S, Leng H, Feng Y,. Wild Bird-Origin H6N2 Influenza Virus Acquires Enhanced Pathogenicity after Single Passage in Mice. Viruses. 2024 Feb 25;16(3):357.  Abstract  
submitted by kickingbird at 9 hours ago from Viruses. 2024 Feb 25;16(3):357 (via https://www.mdpi.com/1999-4915/16/3/357)
The H6 subtype of avian influenza viruses (AIVs) has emerged as one of the predominant subtypes in both wild and domestic avian species. Currently, H6 AIVs have acquired the ability to infect a wide range ...

Mine J, Takadate Y, Kumagai A, Sakuma S, Tsunekuni. Genetics of H5N1 and H5N8 High-Pathogenicity Avian Influenza Viruses Isolated in Japan in Winter 2021-2022. Viruses. 2024 Feb 26;16(3):358.  Abstract  
submitted by kickingbird at 9 hours ago from Viruses. 2024 Feb 26;16(3):358 (via https://www.mdpi.com/1999-4915/16/3/358)
In winter 2021-2022, H5N1 and H5N8 high-pathogenicity avian influenza (HPAI) viruses (HPAIVs) caused serious outbreaks in Japan: 25 outbreaks of HPAI at poultry farms and 107 cases in wild birds or in ...

Guan L, Babujee L, Presler R, Pattinson D, Nguyen. Avian H6 Influenza Viruses in Vietnamese Live Bird Markets during 2018-2021. Viruses. 2024 Feb 27;16(3):367.  Abstract  
submitted by kickingbird at 9 hours ago from Viruses. 2024 Feb 27;16(3):367 (via https://www.mdpi.com/1999-4915/16/3/367)
Avian influenza viruses of the H6 subtype are prevalent in wild ducks and likely play an important role in the ecology of influenza viruses through reassortment with other avian influenza viruses. Yet, ...

Gaymard A, Picard C, Vazzoler G, Massin P, Frobert. Impact of the H274Y Substitution on N1, N4, N5, and N8 Neuraminidase Enzymatic Properties and Expression in Reverse Genetic Influenza A Viruses. Viruses. 2024 Mar 1;16(3):388.  Abstract  
submitted by kickingbird at 9 hours ago from Viruses. 2024 Mar 1;16(3):388 (via https://www.mdpi.com/1999-4915/16/3/388)
The H274Y substitution (N2 numbering) in neuraminidase (NA) N1 confers oseltamivir resistance to A(H1N1) influenza viruses. This resistance has been associated with reduced N1 expression using transfected ...

Quignon E, Ferhadian D, Hache A, Vivet-Boudou V, I. Structural Impact of the Interaction of the Influenza A Virus Nucleoprotein with Genomic RNA Segments. Viruses. 2024 Mar 9;16(3):421.  Abstract  
submitted by kickingbird at 9 hours ago from Viruses. 2024 Mar 9;16(3):421 (via https://www.mdpi.com/1999-4915/16/3/421)
Influenza A viruses (IAVs) possess a segmented genome consisting of eight viral RNAs (vRNAs) associated with multiple copies of viral nucleoprotein (NP) and a viral polymerase complex. Despite the crucial ...

Wang Q, Luo J, Li B, Ye Q, Xu W, Gao F, Zhou L, Lu. Reduction in Interferon-Stimulated Genes Contributes to High-Yield Production of Influenza Virus in Suspension MDCK Cells. Vaccines (Basel). 2024 Mar 9;12(3):287.  Abstract  
submitted by kickingbird at 9 hours ago from Vaccines (Basel). 2024 Mar 9;12(3):287 (via https://www.mdpi.com/2076-393X/12/3/287)
Compared with the traditional vaccine produced in embryonated chicken eggs, cell-based manufacturing represented by the Madin-Darby canine kidney (MDCK) cell line has a larger production scale and reduces ...

Costantino C, Mazzucco W, Graziano G, Maida CM, Vi. Mid-Term Estimates of Influenza Vaccine Effectiveness against the A(H1N1)pdm09 Prevalent Circulating Subtype in the 2023/24 Season: Data from the Sicilian RespiVirNet Surveillance System. Vaccines (Basel). 2024 Mar 14;12(3):305.  Abstract  
submitted by kickingbird at 9 hours ago from Vaccines (Basel). 2024 Mar 14;12(3):305 (via https://www.mdpi.com/2076-393X/12/3/305)
The current influenza season started in Italy in October 2023, approaching the epidemic peak in late December (52nd week of the year). We aimed to explore the mid-term virologic surveillance data of the ...

Allen JD, Ross TM. mRNA vaccines encoding computationally optimized hemagglutinin elicit protective antibodies against future antigenically drifted H1N1 and H3N2 influenza viruses isolated between 2018-2020. Front Immunol. 2024 Mar 12;15:1334670.  Abstract  
submitted by kickingbird at 1 days ago from Front Immunol. 2024 Mar 12;15:1334670 (via https://www.frontiersin.org/journals/immunology/articles/10.)
Background: The implementation of mRNA vaccines against COVID-19 has successfully validated the safety and efficacy of the platform, while at the same time revealing the potential for their applications ...

Jiang S, Li J, Cao J, Ou Y, Duan Y, Gan X. Clinical Characteristics of 118 Pediatric Patients With Acute Benign Myositis Associated With Influenza A Virus Infection. Pediatr Infect Dis J. 2024 Mar 27.  Abstract  
submitted by kickingbird at 1 days ago from Pediatr Infect Dis J. 2024 Mar 27 (via https://journals.lww.com/pidj/abstract/9900/clinical_charact)
Objective: The objective of this study was to investigate the clinical and laboratory features of acute benign myositis associated with influenza A virus infection in children.Methods: A retrospective ...

De Conto F. Avian Influenza A Viruses Modulate the Cellular Cytoskeleton during Infection of Mammalian Hosts. Pathogens. 2024 Mar 14;13(3):249.  Abstract  
submitted by kickingbird at 1 days ago from Pathogens. 2024 Mar 14;13(3):249 (via https://www.mdpi.com/2076-0817/13/3/249)
Influenza is one of the most prevalent causes of death worldwide. Influenza A viruses (IAVs) naturally infect various avian and mammalian hosts, causing seasonal epidemics and periodic pandemics with high ...

Wang Y, Yang C, Liu Y, Zhang J, Qu W, Liang J, Tu. Seroprevalence of Avian Influenza A(H5N6) Virus Infection, Guangdong Province, China, 2022. Emerg Infect Dis. 2024 Apr;30(4):826-828.  Abstract  
submitted by kickingbird at 3 days ago from Emerg Infect Dis. 2024 Apr;30(4):826-828 (via https://wwwnc.cdc.gov/eid/article/30/4/23-1226_article)
In 2022, we assessed avian influenza A virus subtype H5N6 seroprevalence among the general population in Guangdong Province, China, amid rising numbers of human infections. Among the tested samples, we ...

Rachmat A, Kelly GC, Tran LK, Christy N, Supaprom. Clinical Presentation, Risk Factors, and Comparison of Laboratory Diagnostics for Seasonal Influenza Virus Among Cambodians From 2007 to 2020. Open Forum Infect Dis. 2024 Feb 22;11(3):ofae062.  Abstract  
submitted by kickingbird at 3 days ago from Open Forum Infect Dis. 2024 Feb 22;11(3):ofae062 (via https://academic.oup.com/ofid/article/11/3/ofae062/7612558)
Background: Despite its global significance, challenges associated with understanding the epidemiology and accurately detecting, measuring, and characterizing the true burden of seasonal influenza remain ...

Kleij L, Bruder E, Raoux-Barbot D, Lejal N, Nevers. Genomic characterization of equine influenza A subtype H3N8 viruses by long read sequencing and functional analyses of the PB1-F2 virulence factor of A/equine/Paris/1/2018. Vet Res. 2024 Mar 22;55(1):36.  Abstract  
submitted by kickingbird at 5 days ago from Vet Res. 2024 Mar 22;55(1):36 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Equine influenza virus (EIV) remains a threat to horses, despite the availability of vaccines. Strategies to monitor the virus and prevent potential vaccine failure revolve around serological assays, RT-qPCR ...

Bai Y, Lei H, Song W, Shin SC, Wang J, Xiao B, Ko?. Amino acids in the polymerase complex of shorebird-isolated H1N1 influenza virus impact replication and host-virus interactions in mammalian models. Emerg Microbes Infect. 2024 Mar 22:2332652.  Abstract  
submitted by kickingbird at 6 days ago from Emerg Microbes Infect. 2024 Mar 22:2332652 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
A diverse population of avian influenza A viruses (AIVs) are maintained in wild birds and ducks yet the zoonotic potential of AIVs in these environmental reservoirs and the host-virus interactions involved ...

Shi H, Ross TM. Inactivated recombinant influenza vaccine: the promising direction for the next generation of influenza vaccine. Expert Rev Vaccines. 2024 Mar 20.  Abstract  
submitted by kickingbird at 7 days ago from Expert Rev Vaccines. 2024 Mar 20 (via https://www.tandfonline.com/doi/full/10.1080/14760584.2024.2)
Introduction: Vaccination is the most effective method to control the prevalence of seasonal influenza and the most widely used influenza vaccine is the inactivated influenza vaccine (IIV). Each season, ...

Zhou Y, Li T, Zhang Y, Zhang N, Guo Y, Gao X, Peng. BAG6 inhibits influenza A virus replication by inducing viral polymerase subunit PB2 degradation and perturbing RdRp complex assembly. PLoS Pathog. 2024 Mar 18;20(3):e1012110.  Abstract  
submitted by kickingbird at 9 days ago from PLoS Pathog. 2024 Mar 18;20(3):e1012110 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The interaction between influenza A virus (IAV) and host proteins is an important process that greatly influences viral replication and pathogenicity. PB2 protein is a subunit of viral ribonucleoprotein ...

Pulit-Penaloza JA, Brock N, Belser JA, Sun X, Papp. Highly pathogenic avian influenza A(H5N1) virus of clade 2.3.4.4b isolated from a human case in Chile causes fatal disease and transmits between co-housed ferrets. Emerg Microbes Infect. 2024 Mar 17:2332667.  Abstract  
submitted by kickingbird at 11 days ago from Emerg Microbes Infect. 2024 Mar 17:2332667 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses have caused large outbreaks within avian populations on five continents, with concurrent spillover into a variety of mammalian species. ...

Domnich A, Orsi A, Signori A, Chironna M, Manini I. Waning intra-season vaccine effectiveness against influenza A(H3N2) underlines the need for more durable protection. Expert Rev Vaccines. 2024 Jan-Dec;23(1):380-388.  Abstract  
submitted by kickingbird at 11 days ago from Expert Rev Vaccines. 2024 Jan-Dec;23(1):380-388 (via https://www.tandfonline.com/doi/full/10.1080/14760584.2024.2)
Background: The question of whether influenza vaccine effectiveness (VE) wanes over the winter season is still open and some contradictory findings have been reported. This study investigated the possible ...

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