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2024-12-11 12:04:16
Article

Elyse Stachler, etc.,al. [preprint]Establishing methods to monitor H5N1 influenza virus in dairy cattle milk. https://doi.org/10.1101/2024.12.04.24318491.  Abstract  
submitted by kickingbird at 42 minute(s) ago from https://doi.org/10.1101/2024.12.04.24318491 (via https://www.medrxiv.org/content/10.1101/2024.12.04.24318491v)
Highly Pathogenic Avian Influenza strain H5N1 has caused a multi-state outbreak among US dairy cattle, spreading across 15 states and infecting hundreds of herds since its onset. We rapidly developed and ...

Hubbard LE, Stelzer EA, Poulson RL, Kolpin DW, Sza. Development of a Large-Volume Concentration Method to Recover Infectious Avian Influenza Virus from the Aquatic Environment. Viruses. 2024; 16(12):1898.  Abstract  
submitted by kickingbird at 46 minute(s) ago from Viruses. 2024; 16(12):1898 (via https://www.mdpi.com/1999-4915/16/12/1898)
Since late 2021, outbreaks of highly pathogenic avian influenza virus have caused a record number of mortalities in wild birds, domestic poultry, and mammals in North America. Wetlands are plausible environmental ...

Ramos-Martínez I, Ramos-Martínez E, Saavedra-Monta. Meta-Analysis of Seroprevalence and Prevalence of Influenza A Viruses (Subtypes H3N2, H3N8, and H1N1) in Dogs. Animals. 2024; 14(23):3467.  Abstract  
submitted by kickingbird at 48 minute(s) ago from Animals. 2024; 14(23):3467 (via https://www.mdpi.com/2076-2615/14/23/3467)
Influenza A is a zoonotic disease that affects dogs. In this work, we performed a meta-analysis of the prevalence and seroprevalence of reports from all over the world. We found a combined seroprevalence ...

Ismaila Shittu, etc.,al. A One Health Investigation into H5N1 Avian Influenza Virus Epizootics on Two Dairy Farms. Clinical Infectious Diseases, ciae576.  Abstract  
submitted by kickingbird at 54 minute(s) ago from Clinical Infectious Diseases, ciae576 (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
BackgroundIn early April 2024 we studied two Texas dairy farms which had suffered incursions of H5N1 highly pathogenic avian influenza virus (HPAIV) the previous month.MethodsWe employed molecular assays, ...

Yong Zhou, etc.,al. Origin, spread, and interspecies transmission of a dominant genotype of BJ/94 lineage H9N2 avian influenza viruses with increased threat. Virus Evolution, veae106.  Abstract  
submitted by kickingbird at 55 minute(s) ago from Virus Evolution, veae106 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
The H9N2 subtype of avian influenza viruses (AIVs) is widely prevalent in poultry and wild birds globally, with occasional transmission to humans. In comparison to other H9N2 lineages, the BJ/94 lineage ...

Feng Wen, etc.,al. Novel human-type receptor-binding H5N1 virus in live poultry markets, China. The Lancet Microbe.  Abstract  
submitted by kickingbird at 1 hours ago from The Lancet Microbe (via https://www.sciencedirect.com/science/article/pii/S266652472)
Avian influenza viruses represent a considerable public health risk, with the capability to cross species barriers and cause severe disease in humans. The emergence of H5N1 subtype of highly pathogenic ...

Ankerhold J, Kessler S, Beer M, Schwemmle M, Cimin. Replication Restriction of Influenza A(H5N1) Clade 2.3.4.4b Viruses by Human Immune Factor, 2023–2024. Emerg Infect Dis. 2025 Jan.  Abstract  
submitted by kickingbird at 1 hours ago from Emerg Infect Dis. 2025 Jan (via https://wwwnc.cdc.gov/eid/article/31/1/24-1236_article)
We show that human myxovirus resistance protein 1 (MxA) suppresses replication of highly pathogenic avian influenza A(H5N1) viruses isolated from mammals in vitro and in MxA-transgenic mice. However, H5N1 ...

Sarsenov R, Babenko D, Kamalova D, Amirgazin A, Be. Complete genome sequence of a human influenza a virus (H1N1) detected in Kazakhstan in the fall of 2022. Microbiol Resour Announc. 2024 Dec 10:e0104024.  Abstract  
submitted by kickingbird at 4 hours ago from Microbiol Resour Announc. 2024 Dec 10:e0104024 (via https://journals.asm.org/doi/10.1128/mra.01040-24)
An Orthomyxoviridae Alphainfluenza virus Influenza A virus strain, A/Kazakhstan/Flu-H11-6/2022(H1N1), was isolated in Karaganda, Central Kazakhstan during a study of acute respiratory infections among ...

Yin Y, Kan X, Miao X, Sun Y, Chen S, Qin T, Ding C. H5 subtype avian influenza virus induces Golgi apparatus stress response via TFE3 pathway to promote virus replication. PLoS Pathog. 2024 Dec 9;20(12):e1012748.  Abstract  
submitted by kickingbird at 1 days ago from PLoS Pathog. 2024 Dec 9;20(12):e1012748 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
During infection, avian influenza virus (AIV) triggers endoplasmic reticulum (ER) stress, a well-established phenomenon in previous research. The Golgi apparatus, situated downstream of the ER and crucial ...

Xia M, Huang P, Vago FS, Jiang W, Tan M. Pseudovirus nanoparticles targeting the receptor binding HA1 domains of influenza viruses elicited high HA1-specific antibody responses and protected mice against mortality caused by influenza virus c. Vaccine. 2024 Dec 7:126585.  Abstract  
submitted by kickingbird at 2 days ago from Vaccine. 2024 Dec 7:126585 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
The continually high disease burden of influenza and the relatively low effectiveness of current influenza vaccines call for enhanced vaccine strategies. We previously generated unique S-HA1 pseudovirus ...

Chothe SK, Srinivas S, Misra S, Nallipogu NC, Gilb. Marked Neurotropism and Potential Adaptation of H5N1 Clade 2.3.4.4.b Virus in Naturally Infected Domestic Cats. Emerg Microbes Infect. 2024 Dec 9:2440498.  Abstract  
submitted by kickingbird at 2 days ago from Emerg Microbes Infect. 2024 Dec 9:2440498 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
In April 2024, ten cats died in a rural South Dakota (SD) residence, showing respiratory and neurological symptoms. Necropsy and laboratory testing of two cats confirmed H5N1 clade 2.3.4.4b infection. ...

Mancini P, Brandtner D, Veneri C, Bonanno Ferraro. Evaluation of Trends in Influenza A and B Viruses in Wastewater and Human Surveillance Data: Insights from the 2022-2023 Season in Italy. Food Environ Virol. 2024 Dec 7;17(1):6.  Abstract  
submitted by kickingbird at 3 days ago from Food Environ Virol. 2024 Dec 7;17(1):6 (via https://link.springer.com/article/10.1007/s12560-024-09622-2)
Wastewater-based epidemiology (WBE) is a recognized, dynamic approach to monitoring the transmission of pathogens in communities through urban wastewater. This study aimed to detect and quantify influenza ...

Gunasekara E, Hair-Bejo M, Aini I, Omar AR. Molecular characterisation of novel reassortants of the G57 genotype of low-pathogenic avian influenza H9N2 virus isolated from poultry farms in Malaysia. Arch Virol. 2024 Dec 7;170(1):3.  Abstract  
submitted by kickingbird at 3 days ago from Arch Virol. 2024 Dec 7;170(1):3 (via https://link.springer.com/article/10.1007/s00705-024-06159-4)
In late 2017, Malaysia reported repeated outbreaks of low-pathogenic avian influenza virus (LPAI) H9N2 infections in commercial poultry flocks. Two H9N2 viruses, A/chicken/Malaysia/Negeri Sembilan/UPM994/2018 ...

Isabela Carvalho Brcko, etc.,al. Comprehensive Molecular Epidemiology of Influenza Viruses in Brazil: Insights from a Nationwide Analysis. Virus Evolution, veae102.  Abstract  
submitted by kickingbird at 4 days ago from Virus Evolution, veae102 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
Influenza A and B viruses represent significant global health threats, contributing substantially to morbidity and mortality rates. However, a comprehensive understanding of the molecular epidemiology ...

Feixia Gao, Qi Wang, Chenchen Qiu, etc.,al. Pandemic preparedness of effective vaccines for the outbreak of newly H5N1 highly pathogenic avian influenza virus. Virologica Sinica.  Abstract  
submitted by kickingbird at 4 days ago from Virologica Sinica (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Highly pathogenic avian influenza (HPAI) viruses such as H5N1, H5N8, H5N6 and H5N2 have been circulating worldwide, posing serious threats to both poultry farming and public health. Notably, the H5N1, ...

Jiawei Luo, etc.,al. The PB1 protein of H9N2 influenza A virus inhibits antiviral innate immunity by targeting MAVS for TRIM25-mediated autophagic degradation. Poultry Science.  Abstract  
submitted by kickingbird at 4 days ago from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
The proteins encoded by Influenza A virus (IAV) evade the innate immune system through diverse strategies to facilitate their replication. However, the regulatory mechanisms remain not fully understood. ...

Nuo Xu, etc.,al. The evolution of hemagglutinin-158 and neuraminidase-88 glycosylation sites modulates antigenicity and pathogenicity of clade 2.3.2.1 H5N1 avian influenza viruses. Veterinary Microbiology.  Abstract  
submitted by kickingbird at 4 days ago from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Clade 2.3.2.1 of the H5N1 avian influenza virus (AIV) evolved into several subclades. However, the effect of glycosylation on the biological characteristics of hemagglutinin (HA) and/or neuraminidase (NA) ...

Damdinjav B, Raveendran S, Mojsiejczuk L, Ankhanba. Evidence of Influenza A(H5N1) Spillover Infections in Horses, Mongolia. Emerg Infect Dis. 2025 Jan.  Abstract  
submitted by kickingbird at 4 days ago from Emerg Infect Dis. 2025 Jan (via https://wwwnc.cdc.gov/eid/article/31/1/24-1266_article)
Recent outbreaks of influenza A(H5N1) have affected many mammal species. We report serologic evidence of H5N1 virus infection in horses in Mongolia. Because H3N8 equine influenza virus is endemic in many ...

Loureiro CL, Bonetti V, Jaspe RC, Sulbaran Y, Alca. Analysis of the Monophyletic Lineage of Avian Influenza H5N1 Which Circulated in Venezuelan Birds During the 2022–2023 Outbreak. Microorganisms. 2024; 12(12):2519.  Abstract  
submitted by kickingbird at 4 days ago from Microorganisms. 2024; 12(12):2519 (via https://www.mdpi.com/2076-2607/12/12/2519)
Avian influenza subtype H5N1 has caused outbreaks worldwide since 1996, with the emergence of the Guandong lineage in China. The current clade 2.3.4.4b has evolved from this lineage, with increased virulence ...

Matthew L Turnbull, etc.,al. [preprint]POLYGENIC DETERMINANTS OF H5N1 ADAPTATION TO BOVINE CELLS. https://doi.org/10.1101/2024.11.29.626120.  Abstract  
submitted by kickingbird at 5 days ago from https://doi.org/10.1101/2024.11.29.626120 (via https://www.biorxiv.org/content/10.1101/2024.11.29.626120v1)
H5N1 avian influenza virus (lineage 2.3.4.4b, B3.13 genotype) has caused, unexpectedly, a large outbreak in dairy cattle in North America. It is critical to ascertain how this virus has specifically adapted ...

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