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2025-11-15 11:31:43
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Qadir MF, Yang Y. Overcoming Challenges in Avian Influenza Diagnosis: The Role of Surface-Enhanced Raman Spectroscopy in Poultry Health Monitoring. Veterinary Sciences. 2025; 12(11):1052.  Abstract  
submitted by kickingbird at 13 days ago from Veterinary Sciences. 2025; 12(11):1052 (via https://www.mdpi.com/2306-7381/12/11/1052)
Rapid and accurate diagnostics for influenza viruses are essential for preventing future epidemics. Surface-enhanced Raman spectroscopy (SERS) presents a promising alternative to conventional techniques, ...

Stadler, J., Grau, K., Lillie-Jaschniski, K. et al. Diagnostic performance of ELISA kits and expanded antigen panels for hemagglutination inhibition assays in pig herds enzootically infected with porcine Influenza A viruses. Porc Health Manag 11, 53 (2025).  Abstract  
submitted by kickingbird at 13 days ago from Porc Health Manag 11, 53 (2025) (via https://link.springer.com/article/10.1186/s40813-025-00464-3)
BackgroundA combined approach using both indirect and direct detection methods can improve the diagnostic efficiency of swine Influenza A virus (swIAV) infections. Despite its importance, limited research ...

Abdullatif, T.M., Hassanin, O., Mohamed, W. et al. Investigation into the efficacy of a commercially available inactivated avian influenza virus (AIV) vaccine (H9N2) through experimental and field assessments, with an emphasis on its compatibility wit. Vet Res Commun 50, 14 (2026).  Abstract  
submitted by kickingbird at 13 days ago from Vet Res Commun 50, 14 (2026) (via https://link.springer.com/article/10.1007/s11259-025-10919-1)
Avian influenza H9N2 virus has established itself as endemic in various parts of the globe notably in the Middle East with significant economic repercussions. Vaccination with inactivated vaccine is regarded ...

M. Salines, etc.,al. To what extent may the duck population be protected after vaccination against highly pathogenic avian influenza? Contributions from a modelling approach and French field data. Vaccine, Volume 68, 5 December 2025, 127905.  Abstract  
submitted by kickingbird at 13 days ago from Vaccine, Volume 68, 5 December 2025, 127905 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
Faced with increasingly disastrous avian influenza crises, and considering the associated zoonotic risk, France launched a vaccination campaign against highly pathogenic avian influenza on duck farms with ...

Wu, M., Wang, P., Wang, L. et al. Live attenuated influenza vaccine with low proportions of defective interfering particles elicits robust immunogenicity and cross-protection. Nat Commun 16, 9647 (2025).  Abstract  
submitted by kickingbird at 13 days ago from Nat Commun 16, 9647 (2025) (via https://www.nature.com/articles/s41467-025-64651-0)
Commercial live attenuated influenza vaccines (LAIVs) usually contain a high proportion of defective interfering particles (DIPs). Given that LAIVs are not sufficiently protective worldwide, the potential ...

Stadler, J., Grau, K., Lillie-Jaschniski, K. et al. Diagnostic performance of ELISA kits and expanded antigen panels for hemagglutination inhibition assays in pig herds enzootically infected with porcine Influenza A viruses. Porc Health Manag 11, 53 (2025).  Abstract  
submitted by kickingbird at Oct, 28, 2025 from Porc Health Manag 11, 53 (2025) (via https://link.springer.com/article/10.1186/s40813-025-00464-3)
BackgroundA combined approach using both indirect and direct detection methods can improve the diagnostic efficiency of swine Influenza A virus (swIAV) infections. Despite its importance, limited research ...

Zhao L, Huang Z, Long W. China’s Invisible Chicken Losses: Production Costs Effect of Highly Pathogenic Avian Influenza. Agriculture. 2025; 15(20):2176.  Abstract  
submitted by kickingbird at Oct, 22, 2025 from Agriculture. 2025; 15(20):2176 (via https://www.mdpi.com/2077-0472/15/20/2176)
Highly pathogenic avian influenza (HPAI) affects chicken production not only during outbreaks but also afterward. Understanding its delayed effect is essential for facilitating timely production recovery. ...

Bacsik DJ, Mills MG, Monroe LD, Spring C, Perez-Os. Validation of H5 influenza virus subtyping RT-qPCR assay and low prevalence of H5 detection in 2024-2025 influenza virus season. J Clin Microbiol. 2025 Oct 21:e0041525.  Abstract  
submitted by kickingbird at Oct, 22, 2025 from J Clin Microbiol. 2025 Oct 21:e0041525 (via https://journals.asm.org/doi/10.1128/jcm.00415-25)
A sustained outbreak of H5N1 influenza virus among wild fowl and domestic livestock has caused more than 70 zoonotic infections in humans in North America, including two deaths. The United States Centers ...

Kok, A., Wilks, S.H., Tureli, S. et al. A vaccine central in A(H5) influenza antigenic space confers broad immunity. Nature (2025).  Abstract  
submitted by kickingbird at Oct, 16, 2025 from Nature (2025) (via https://link.springer.com/article/10.1038/s41586-025-09626-3)
Highly pathogenic avian influenza A(H5) viruses globally impact wild and domestic birds, and have caused severe infections in mammals, including humans, underscoring their pandemic potential1,2,3,4,5. ...

Lasrado N, Wang L, Liu J, R?ssler A, Chaudhari J,. An intramuscular prime and mucosal boost vaccine regimen protects against lethal clade 2.3.4.4b H5N1 challenge in cynomolgus macaques. Sci Transl Med. 2025 Oct 15;17(820):eady2282.  Abstract  
submitted by kickingbird at Oct, 16, 2025 from Sci Transl Med. 2025 Oct 15;17(820):eady2282 (via https://www.science.org/doi/10.1126/scitranslmed.ady2282)
The H5N1 clade 2.3.4.4b avian influenza virus outbreak in poultry and dairy cattle is a potential pandemic threat for humans. A safe and effective H5N1 influenza vaccine will be needed if the virus acquires ...

Yulia Sergeeva, etc.,al. Gold Nanoparticles with Adaptable Self-Assembled Monolayer Shells Allow Multivalent Inhibition and Sensing of Influenza Virus at Ultralow Concentrations. ACS Cent. Sci. 2025, 11, 9, 1659–1669.  Abstract  
submitted by kickingbird at Oct, 13, 2025 from ACS Cent. Sci. 2025, 11, 9, 1659–1669 (via https://pubs.acs.org/doi/10.1021/acscentsci.5c00602)
Multivalent inhibitors that mimic the polysaccharide array on cells represent a new paradigm in the development of antiviral agents and antibiotics. Covalent ligand anchoring limits the affinity and, in ...

Martina Raschig, etc.,al. A Viral Neuraminidase-Specific Sensor for Taste-Based Detection of Influenza. ACS Cent. Sci. 2025.  Abstract  
submitted by kickingbird at Oct, 13, 2025 from ACS Cent. Sci. 2025 (via https://pubs.acs.org/doi/10.1021/acscentsci.5c01179)
Influenza has caused the deadliest pandemics in history, thereby prompting advances in our ability to ensure vigilance at all stages of future outbreaks. Quarantining patients early is crucial when it ...

Julia Romanova, etc.,al. Protective efficacy of the UniFluVec influenza vaccine vector against the highly pathogenic influenza A/Indonesia/5/2005 (H5N1) strain in ferrets. Vaccine, Vol 65, 24 Oct 2025, 127795.  Abstract  
submitted by kickingbird at Oct, 11, 2025 from Vaccine, Vol 65, 24 Oct 2025, 127795 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
BackgroundThe emergence of new influenza strains with unpredictable antigenic properties poses a significant vaccination challenge. The increasing incidence of human H5 infections underscores the urgent ...

Meiyan Xin, etc.,al. An H1N1 virus biosensor based on enzyme activity-gated PER-CRISPR/Cas12a cascade signal amplification. Enzyme and Microbial Technology.  Abstract  
submitted by kickingbird at Oct, 11, 2025 from Enzyme and Microbial Technology (via https://www.sciencedirect.com/science/article/abs/pii/S01410)
The rapid and accurate detection of the H1N1 influenza virus is a key link in epidemic prevention and control. This study innovatively constructed a cascade signal amplification biosensor based on DNA ...

An SH, Heo GB, Kang YM, Lee YJ, Lee KN. Development of a multiplex and universal RT-PCR assay for hemagglutinin and neuraminidase subtyping of avian influenza virus. J Vet Sci. 2025 Sep;26(5):e59.  Abstract  
submitted by kickingbird at Oct, 5, 2025 from J Vet Sci. 2025 Sep;26(5):e59 (via https://vetsci.org/DOIx.php?id=10.4142/jvs.25066)
Importance: Avian influenza virus (AIV) is classified into subtypes by hemagglutinin (HA) and neuraminidase (NA) genes. Wild waterfowl harbor H1-H16 and N1-N9 subtypes. Large-scale AIV surveillance requires ...

Amer Alagic. Quality Control Rapid Response in Pre-Pandemic Preparedness Showcasing a Synthetic H5N1 Genetic Template. Clinical Chemistry, Volume 71, Issue Supplement_1.  Abstract  
submitted by kickingbird at Oct, 3, 2025 from Clinical Chemistry, Volume 71, Issue Supplement_1 (via https://academic.oup.com/clinchem/article/71/Supplement_1/hv)
BackgroundThe SARS pandemic presented significant challenges globally, primarily due to the initial lack of well characterized patient samples, which impeded the cross-validation of assays and designs. ...

Liam Brandt, Catherine Huang, Dana Ruminski Lowe,. Development and Performance Evaluation of a Molecular Reference Material for Influenza H5N1 Strain Screening. Clinical Chemistry, Volume 71, Issue Supplement_1.  Abstract  
submitted by kickingbird at Oct, 3, 2025 from Clinical Chemistry, Volume 71, Issue Supplement_1 (via https://academic.oup.com/clinchem/article/71/Supplement_1/hv)
BackgroundInfluenza A H5N1 is a highly pathogenic avian influenza virus strain that poses a significant threat to global public health due to its potential to cause severe illness and widespread outbreaks ...

Wang T, Han R, Li J, Cheng X, Qi Z, Bing J, Zhai C. Novel Mini-Hemagglutinin Subunit Vaccine Induces Robust Mucosal and Systemic Immunity and Protection Against a Lethal Challenge With the H1N1 and H5N1 Influenza Viruses in Mice. J Med Virol. 2025 Oct;97(10):e70614.  Abstract  
submitted by kickingbird at Sep, 25, 2025 from J Med Virol. 2025 Oct;97(10):e70614 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.70614)
Conventional influenza vaccines target the globular head domains of hemagglutinins (HAs), which are highly plastic and provide strain-specific immunity. Therefore, a universal influenza vaccine with conserved ...

Kathryn Kistler, Trevor Bedford. Seasonal influenza viruses show distinct adaptive dynamics during growth in chicken eggs. Molecular Biology and Evolution, 2025;, msaf227.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from Molecular Biology and Evolution, 2025;, msaf227 (via https://academic.oup.com/mbe/advance-article/doi/10.1093/mol)
Human influenza viruses are grown in chicken eggs for vaccine production. Sequences of these egg-passaged viruses give us the opportunity to examine the evolution that occurs when these human viruses are ...

Qiao Y, Tang M, Du M, Zhao C, Lv Y, Zhou J, Liu Y,. H5N1 influenza virus-like particles based on BEVS induce robust functional antibodies and immune responses. Virology. 2025 Aug 29;612:110672.  Abstract  
submitted by kickingbird at Sep, 9, 2025 from Virology. 2025 Aug 29;612:110672 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Avian influenza virus infections pose a potential pandemic threat. The currently licensed vaccines have inherent limitations, emphasizing the urgent need for improved influenza vaccines. Here, we developed ...

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