Higerd-Rusli GP, Hoffman SA, Karan A, Huang C, Sah. Validation of sample pooling for high-throughput RT-qPCR subtyping of avian influenza A(H5). Microbiol Spectr 0:e00850-26. Abstract
submitted by kickingbird at 3 days ago from Microbiol Spectr 0:e00850-26 (via https://journals.asm.org/doi/10.1128/spectrum.00850-26)
Highly pathogenic avian influenza A(H5N1) is a global health threat due to its high historical virulence and increasing mammalian host range, as demonstrated by the 2024–2025 outbreak among U.S. dairy ... Pyles, K., Darling, T.L., Huang, LC. et al. Intranasal and intramuscular H5-Matrix-M nanoparticle vaccines protects against highly pathogenic H5N1 influenza virus in mice. npj Vaccines (2026). Abstract
submitted by kickingbird at 5 days ago from npj Vaccines (2026) (via https://link.springer.com/article/10.1038/s41541-026-01523-8)
The emergence of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in dairy cows and transmission to humans has heightened public health concerns. In this work, we characterized the immunogenicity ... Ana Clara Silva Stival, Artur Christian Garcia d. Qualitative and quantitative evaluation of Fetal Bovine Serum composition: toward ethical and best quality in vitro science. NAM Journal. Abstract
submitted by kickingbird at 9 days ago from NAM Journal (via https://www.sciencedirect.com/science/article/pii/S305062042)
Fetal bovine serum (FBS) is widely used as a supplement in cell culture due to its complex composition, which supports cell growth, and metabolism for conducting experiments with mammalian cells in vitro. ... Pecora A, Pérez López J, Jordán MJ, Franco LN, Pol. Analysis of irradiated Argentinean fetal bovine serum for adventitious agents. J Vet Diagn Invest. 2020 Nov;32(6):892-897. Abstract
submitted by kickingbird at 9 days ago from J Vet Diagn Invest. 2020 Nov;32(6):892-897 (via https://sage.cnpereading.com/doi/10.1177/1040638720951556)
Fetal bovine serum (FBS) used in cell culture may be contaminated with adventitious agents, which can affect the production of biologicals and the results of clinical laboratory tests. We carried out a ... Sadeghi M, etc.,al. Virome of US bovine calf serum. Biologicals. 2017 Mar;46:64-67. Abstract
submitted by kickingbird at 9 days ago from Biologicals. 2017 Mar;46:64-67 (via https://www.sciencedirect.com/science/article/abs/pii/S10451)
Using viral metagenomics we analyzed four bovine serum pools assembled from 715 calves in the United States. Two parvoviruses, bovine parvovirus 2 (BPV2) and a previously uncharacterized parvovirus designated ... Yang K, Yang G, Xia Y, Ou X. Synthetic Biology Strategies for the Development of Live Attenuated Influenza Viruses: Recent Advances and Applications. Viruses. 2026; 18(7):715. Abstract
submitted by kickingbird at Jul, 2, 2026 from Viruses. 2026; 18(7):715 (via https://www.mdpi.com/1999-4915/18/7/715)
Influenza viruses, due to their simple genomic structure and potent immunostimulatory capacity, have been extensively explored for applications in cancer immunotherapy and viral vector vaccine development. ... Yu W, Hu J, Wang X, Hu S, Liu X, Hu Z. Expression of a recombinant DIVA antigen for differential diagnosis of H7N9 subtype avian influenza virus infected and vaccinated chickens. Protein Expr Purif. 2026 Jul 1:106970. Abstract
submitted by kickingbird at Jul, 2, 2026 from Protein Expr Purif. 2026 Jul 1:106970 (via https://www.sciencedirect.com/science/article/abs/pii/S10465)
H7N9 subtype avian influenza virus (AIV) is a great threat for poultry industry in China. Serological assays that differentiate infected and vaccinated animals (DIVA) can facilitate H7N9 virus monitoring ... Liu Z, Zhou P, Jia X, Liu X, Yang Y, Sun Y, Xiao R. Three-Dimensional Magnetic Multi-Metallic Nanozymes With Colorimetric and Catalytic Amplification for Rapid and Highly-Sensitive Detection of Influenza A. Exploration (Beijing). 2026 May 20;6(3):20240425. Abstract
submitted by kickingbird at Jul, 2, 2026 from Exploration (Beijing). 2026 May 20;6(3):20240425 (via https://onlinelibrary.wiley.com/doi/10.1002/EXP.20240425)
Lateral flow immunochromatographic assay (LFIA) has been widely used in the point-of-care testing field with fast results readout and portability. Nanozymes-based LFIA strengthened the colorimetric signals ... N. Rikhi, C. J. Sei, K. A. Fraser, et al. Immunogenicity of a Multi-Epitope Influenza Composite Peptide Vaccine Targeting Human, Swine, and Avian Viruses: Advancing Pandemic Preparedness. Influenza and Other Respiratory Viruses. Abstract
submitted by kickingbird at Jun, 29, 2026 from Influenza and Other Respiratory Viruses (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70278)
BackgroundThe emergence of novel reassortant influenza A virus strains and zoonotic transmission to the human population is a critical factor in the development of a global pandemic, as exemplified by ... Maria A. Stincarelli, etc.,al. A colorimetric readout based on the PrestoBlue dye as an objective method for measuring neutralizing antibodies against influenza virus in human serum samples. Biochemistry and Biophysics Reports. Abstract
submitted by kickingbird at Jun, 25, 2026 from Biochemistry and Biophysics Reports (via https://www.sciencedirect.com/science/article/pii/S240558082)
Influenza is an infectious respiratory disease that has significant morbidity and a high mortality rate. The immune responses induced against both seasonal and potentially pandemic strains of the influenza ... Kang H, Gao J, Giurgea L, Memoli MJ, Daniels R. ELISA-based quantification of neuraminidase in commercial influenza vaccines using virus-derived reference antigens. Microbiol Spectr 0:e01227-26. Abstract
submitted by kickingbird at Jun, 25, 2026 from Microbiol Spectr 0:e01227-26 (via https://journals.asm.org/doi/10.1128/spectrum.01227-26)
Most commercial influenza vaccines are produced using inactivated viruses decorated with hemagglutinin (HA) and neuraminidase (NA) antigens from the recommended strains. However, only the HA antigen content ... Esfandiari AH, Afarande H, Amini VR, Hatamluyi B,. Aptamer-based biosensing strategies for influenza virus detection: a systematic and critical review of electrochemical and optical platforms. Crit Rev Clin Lab Sci. 2026 Jun 23:1-25. Abstract
submitted by kickingbird at Jun, 24, 2026 from Crit Rev Clin Lab Sci. 2026 Jun 23:1-25 (via https://www.tandfonline.com/doi/full/10.1080/10408363.2026.2)
Influenza virus remains a major global health challenge due to its genetic variability and frequent emergence of novel strains. Subtyping is determined by the diverse arrangements of hemagglutinin (HA) ... Grant P Higerd-Rusli, Seth A Hoffman, Abraar Karan. Lower limit of detection of commercial respiratory virus reverse transcriptase–polymerase chain reaction panels for bovine influenza A(H5N1). American Journal of Clinical Pathology, Volume 16. Abstract
submitted by kickingbird at Jun, 24, 2026 from American Journal of Clinical Pathology, Volume 16 (via https://academic.oup.com/ajcp/article-abstract/165/6/aqag067)
ObjectivesThe adaptation of clade 2.3.4.4b influenza A(H5N1) to dozens of mammalian species, including dairy cattle, raises concerns about potential spillover into humans. If the virus develops human-to-human ... Jiachen Liu, etc.,al. Engineered Bacillus subtilis to deliver dsRNA via extracellular vesicles against the H9N2 avian influenza virus. Trends in Biotechnology, 2026. Abstract
submitted by kickingbird at Jun, 21, 2026 from Trends in Biotechnology, 2026 (via https://www.cell.com/trends/biotechnology/fulltext/S0167-779)
RNA interference (RNAi) is a potent antiviral approach, outperforming traditional pesticides and broad-spectrum drugs. Its use in animal disease control faces two challenges: inefficient target design ... Wei, D., Pan, Y., Zhang, X. et al. A bivalent mRNA–LNP vaccine confers broad-spectrum protection against both homologous and heterologous H5/H7 highly pathogenic avian influenza viruses in SPF chickens. Vet Res 57, 111 (2026). Abstract
submitted by kickingbird at Jun, 20, 2026 from Vet Res 57, 111 (2026) (via https://link.springer.com/article/10.1186/s13567-026-01790-2)
The continuous evolution and co-circulation of H5 and H7 subtype highly pathogenic avian influenza viruses (HPAIVs) have caused substantial economic losses to the global poultry industry and pose a persistent ... Peng, C., Zhang, C. & Jiang, T. Validation of a Qualitative Detection Method for Influenza A Virus RNA Based on the RT-RPA-CRISPR/Cas13a System. Curr Microbiol 83, 437 (2026). Abstract
submitted by kickingbird at Jun, 20, 2026 from Curr Microbiol 83, 437 (2026) (via https://link.springer.com/article/10.1007/s00284-026-05028-4)
Seasonal influenza A virus (IAV) frequently causes outbreaks, creating an urgent need for rapid, cost-effective detection. Existing methods have limitations: antigen tests lack sensitivity, RT-qPCR (the ... Ao Z, Vendramelli R, Buyu M, Truong T, Liu D, Gao. A VSV-vector vaccine simultaneously targeting H5N1 hemagglutinin and matrix protein 2 induces robust neutralizing and ADCC antibody responses and provides full protection against lethal H5N1 infection. J Virol 0:e00097-26. Abstract
submitted by kickingbird at Jun, 18, 2026 from J Virol 0:e00097-26 (via https://journals.asm.org/doi/10.1128/jvi.00097-26)
Avian influenza A viruses, especially highly pathogenic avian influenza (HPAI) viruses, pose a significant public health threat, and a multivalent vaccine is the primary prophylactic measure to control ... Harrington WN, Brice DC, Schmitz AJ, Turner JS, Br. Broadly reactive human monoclonal antibodies targeting influenza a nucleoprotein lack protective activity in vivo. Sci Rep. 2026 Jun 16. Abstract
submitted by kickingbird at Jun, 18, 2026 from Sci Rep. 2026 Jun 16 (via https://www.nature.com/articles/s41598-026-58084-y)
The antibody response to influenza virus infection targets numerous viral proteins, with those specific for the hemagglutinin (HA) and neuraminidase (NA) surface glycoproteins being the most extensively ... Ueki H, Tomita Y, Duong C, Mitake H, Kiso M, Furus. A CRISPR knockout mouse library for functional genomics in influenza research. Cell. 2026 Jun 16:S0092-8674(26)00591-X. Abstract
submitted by kickingbird at Jun, 18, 2026 from Cell. 2026 Jun 16:S0092-8674(26)00591-X (via https://www.cell.com/cell/abstract/S0092-8674(26)00591-X)
Functional validation of host factors in whole-animal models is a major bottleneck in virology; it hinders the translation of data from in vitro studies into a deeper understanding of the viral life cycle ... Xiang F, Xu Y, Liu C, Li X, Wang R, Zhang H, Dong. A reverse genetics-based NS1-truncated live attenuated vaccine confers broad heterologous protection against swine influenza viruses. Microb Pathog. 2026 Jun 16:108638. Abstract
submitted by kickingbird at Jun, 18, 2026 from Microb Pathog. 2026 Jun 16:108638 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Swine influenza A viruses (swIAVs) undergo frequent reassortment and evolution, posing significant threats to both animal and human health. In this study, we employed reverse genetics to generate five ... 388 items, 20/Page, Page[1/20][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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