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2026-8-16 13:30:34
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Aebischer A, Günther A, Piesche R, Wernike K, Murr. Development of a multi-species luciferase-based double-antigen ELISA for the detection of antibodies against influenza A virus H5 clade 2.3.4.4b. J Clin Microbiol. 2026 Aug 13:e0190725.  Abstract  
submitted by kickingbird at 2 days ago from J Clin Microbiol. 2026 Aug 13:e0190725 (via J Clin Microbiol. 2026 Aug 13:e0190725)
The highly pathogenic avian influenza viruses of subtype H5N1 represent a major threat to animal and public health. The current panzootic with H5 clade 2.3.4.4b has caused numerous, widespread outbreaks ...

Rachel C. Williams, etc.,al. Comparative evaluation of sequencing technologies for public health surveillance of influenza virus in wastewater and environmental samples. Water Research.  Abstract  
submitted by kickingbird at 7 days ago from Water Research (via https://www.sciencedirect.com/science/article/abs/pii/S00431)
Influenza viruses, notably influenza A (IAV), remain a persistent public health challenge due to high mutation rates and the rapid emergence of new strains. Wastewater-based epidemiology (WBE) offers a ...

Van Twuijver, E., Versage, E., Jacobs, R. L, Hohenboken, M. Heterologous prime-boost vaccination against H5 avian influenza: Safety and immunogenicity of a MF59-adjuvanted, cell-culture derived H5N6 vaccine. Human Vaccines & Immunotherapeutics, 22(1).  Abstract  
submitted by kickingbird at 10 days ago from Human Vaccines & Immunotherapeutics, 22(1) (via https://www.tandfonline.com/doi/full/10.1080/21645515.2026.2)
With increasing H5 avian influenza cases reported globally and the potential for pandemic emergence, induction of cross-reactive antibody responses may represent an important attribute of an effective ...

Liu Y, Bai M, Zhang T, Cui Y, Du X, Huang L, Zhang. Comparative Immunogenicity of Inactivated H7N9 Avian Influenza Vaccines with Different Internal Gene Backbones. Microorganisms. 2026; 14(8):1719.  Abstract  
submitted by kickingbird at 10 days ago from Microorganisms. 2026; 14(8):1719 (via https://www.mdpi.com/2076-2607/14/8/1719)
H7N9 avian influenza virus (AIV) poses a persistent threat to poultry and public health. Despite widespread vaccination in China, rapid antigenic drift and reassortment necessitate frequent updates of ...

Xu N, Wang L, Zhao C, Shen Y, Zhao Z, Nie J. Advances in clinical immunogenicity evaluation of influenza vaccines. Vaccine. 2026 Aug 3;89:128989.  Abstract  
submitted by kickingbird at 12 days ago from Vaccine. 2026 Aug 3;89:128989 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Influenza vaccination is an effective intervention for preventing severe influenza, and assessing its immunogenicity is a critical step in determining vaccine protective efficacy. With the widespread use ...

Ximing Zeng, etc.,al. Rapid and specific detection of influenza virus antigens via surface-enhanced Raman scattering-based immunoassay. Talanta.  Abstract  
submitted by kickingbird at 13 days ago from Talanta (via https://www.sciencedirect.com/science/article/abs/pii/S00399)
Influenza is currently one of the most prevalent respiratory diseases in humans, with outbreaks typically occurring during the winter months. Its impact is particularly pronounced among vulnerable populations, ...

Portela Catani, J.P., Smet, A., Ysenbaert, T. et a. Influenza neuraminidase as adjuvanted protein or mRNA vaccine protects mice against influenza A and B virus challenge. npj Vaccines (2026).  Abstract  
submitted by kickingbird at 14 days ago from npj Vaccines (2026) (via https://link.springer.com/article/10.1038/s41541-026-01536-3)
Neuraminidase (NA) is an underutilized influenza vaccine antigen despite its recognized contribution to protective immunity. Here, we compared the immunogenicity and protective potential of multiple NA ...

Kim BK, Park JH, Choi WS, Oh S, An SH, Lee GC, Cho. Capless self-amplifying mRNA vaccine induces dose-sparing protective immunity against HPAI clade 2.3.4.4 H5 virus in mice. Mol Ther. 2026 Jul 29:S1525-0016(26)00668-4.  Abstract  
submitted by kickingbird at 15 days ago from Mol Ther. 2026 Jul 29:S1525-0016(26)00668-4 (via https://www.cell.com/molecular-therapy-family/molecular-ther)
Self-amplifying mRNA (samRNA) vaccines can induce potent immune responses at lower doses than conventional non-replicating mRNA vaccines; however, large RNA size and manufacturing considerations associated ...

Raymond Ash, etc.,al. Contribution of Influenza H5 Head and Stalk Domains to the Development of Functional Non-Neutralizing Antibodies Following Mucosal rH5-NE Vaccination. The Journal of Immunology.  Abstract  
submitted by kickingbird at Jul, 29, 2026 from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/Supplement_1/v)
IntroductionIn a prior Phase 1 trial we showed that an intranasal (IN) recombinant hemagglutinin (HA) H5 vaccine (rH5; A/Indo/05) nanoemulsion-adjuvanted (rH5 NE) and given on days 1 and 29 effectively ...

Zelmar Rodriguez, etc.,al. Long-term milk-yield impact and recovery in HPAI-affected cows across consecutive lactations and its association with antibody response. Journal of Dairy Science.  Abstract  
submitted by kickingbird at Jul, 28, 2026 from Journal of Dairy Science (via https://www.sciencedirect.com/science/article/pii/S002203022)
This cohort study quantifies the long-term impact of HPAI H5N1 on cumulative milk yield and milk-yield trajectories during the affected lactation, and carryover effects in the subsequent lactation; and ...

Liu B, Li F, Yang Y, Tu H, Hao P, Ma Q, Le Y, Zhan. In-depth monitoring of host cell proteins in influenza vaccines throughout multi-step purification processes. Vaccine. 2026 Jul 25;88:128957.  Abstract  
submitted by kickingbird at Jul, 27, 2026 from Vaccine. 2026 Jul 25;88:128957 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Influenza viruses, characterized by antigenic drift and shift, can cause seasonal epidemics or pandemics. According to World Health Organization (WHO) data, approximately 650,000 global annual deaths are ...

Higerd-Rusli GP, Hoffman SA, Karan A, Huang C, Sah. Validation of sample pooling for high-throughput RT-qPCR subtyping of avian influenza A(H5). Microbiol Spectr 0:e00850-26.  Abstract  
submitted by kickingbird at Jul, 15, 2026 from Microbiol Spectr 0:e00850-26 (via https://journals.asm.org/doi/10.1128/spectrum.00850-26)
Highly pathogenic avian influenza A(H5N1) is a global health threat due to its high historical virulence and increasing mammalian host range, as demonstrated by the 2024–2025 outbreak among U.S. dairy ...

Pyles, K., Darling, T.L., Huang, LC. et al. Intranasal and intramuscular H5-Matrix-M nanoparticle vaccines protects against highly pathogenic H5N1 influenza virus in mice. npj Vaccines (2026).  Abstract  
submitted by kickingbird at Jul, 13, 2026 from npj Vaccines (2026) (via https://link.springer.com/article/10.1038/s41541-026-01523-8)
The emergence of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in dairy cows and transmission to humans has heightened public health concerns. In this work, we characterized the immunogenicity ...

Ana Clara Silva Stival, Artur Christian Garcia d. Qualitative and quantitative evaluation of Fetal Bovine Serum composition: toward ethical and best quality in vitro science. NAM Journal.  Abstract  
submitted by kickingbird at Jul, 9, 2026 from NAM Journal (via https://www.sciencedirect.com/science/article/pii/S305062042)
Fetal bovine serum (FBS) is widely used as a supplement in cell culture due to its complex composition, which supports cell growth, and metabolism for conducting experiments with mammalian cells in vitro. ...

Pecora A, Pérez López J, Jordán MJ, Franco LN, Pol. Analysis of irradiated Argentinean fetal bovine serum for adventitious agents. J Vet Diagn Invest. 2020 Nov;32(6):892-897.  Abstract  
submitted by kickingbird at Jul, 9, 2026 from J Vet Diagn Invest. 2020 Nov;32(6):892-897 (via https://sage.cnpereading.com/doi/10.1177/1040638720951556)
Fetal bovine serum (FBS) used in cell culture may be contaminated with adventitious agents, which can affect the production of biologicals and the results of clinical laboratory tests. We carried out a ...

Sadeghi M, etc.,al. Virome of US bovine calf serum. Biologicals. 2017 Mar;46:64-67.  Abstract  
submitted by kickingbird at Jul, 9, 2026 from Biologicals. 2017 Mar;46:64-67 (via https://www.sciencedirect.com/science/article/abs/pii/S10451)
Using viral metagenomics we analyzed four bovine serum pools assembled from 715 calves in the United States. Two parvoviruses, bovine parvovirus 2 (BPV2) and a previously uncharacterized parvovirus designated ...

Yang K, Yang G, Xia Y, Ou X. Synthetic Biology Strategies for the Development of Live Attenuated Influenza Viruses: Recent Advances and Applications. Viruses. 2026; 18(7):715.  Abstract  
submitted by kickingbird at Jul, 2, 2026 from Viruses. 2026; 18(7):715 (via https://www.mdpi.com/1999-4915/18/7/715)
Influenza viruses, due to their simple genomic structure and potent immunostimulatory capacity, have been extensively explored for applications in cancer immunotherapy and viral vector vaccine development. ...

Yu W, Hu J, Wang X, Hu S, Liu X, Hu Z. Expression of a recombinant DIVA antigen for differential diagnosis of H7N9 subtype avian influenza virus infected and vaccinated chickens. Protein Expr Purif. 2026 Jul 1:106970.  Abstract  
submitted by kickingbird at Jul, 2, 2026 from Protein Expr Purif. 2026 Jul 1:106970 (via https://www.sciencedirect.com/science/article/abs/pii/S10465)
H7N9 subtype avian influenza virus (AIV) is a great threat for poultry industry in China. Serological assays that differentiate infected and vaccinated animals (DIVA) can facilitate H7N9 virus monitoring ...

Liu Z, Zhou P, Jia X, Liu X, Yang Y, Sun Y, Xiao R. Three-Dimensional Magnetic Multi-Metallic Nanozymes With Colorimetric and Catalytic Amplification for Rapid and Highly-Sensitive Detection of Influenza A. Exploration (Beijing). 2026 May 20;6(3):20240425.  Abstract  
submitted by kickingbird at Jul, 2, 2026 from Exploration (Beijing). 2026 May 20;6(3):20240425 (via https://onlinelibrary.wiley.com/doi/10.1002/EXP.20240425)
Lateral flow immunochromatographic assay (LFIA) has been widely used in the point-of-care testing field with fast results readout and portability. Nanozymes-based LFIA strengthened the colorimetric signals ...

N. Rikhi, C. J. Sei, K. A. Fraser, et al. Immunogenicity of a Multi-Epitope Influenza Composite Peptide Vaccine Targeting Human, Swine, and Avian Viruses: Advancing Pandemic Preparedness. Influenza and Other Respiratory Viruses.  Abstract  
submitted by kickingbird at Jun, 29, 2026 from Influenza and Other Respiratory Viruses (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70278)
BackgroundThe emergence of novel reassortant influenza A virus strains and zoonotic transmission to the human population is a critical factor in the development of a global pandemic, as exemplified by ...

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