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2024-5-21 13:43:26
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Li X, et al. Characterization of avian influenza H5N3 reassortants isolated from migratory waterfowl and domestic ducks in China from 2015 to 2018. Transbound Emerg Dis. 2019 Aug 11..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Transbound Emerg Dis. 2019 Aug 11. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13324)
Wild and domestic aquatic birds are the natural reservoirs of avian influenza viruses (AIVs). All subtypes of AIVs, including 16 hemagglutinin (HA) and nine neuraminidase (NA), have been isolated from ...

Trost JF, et al. A conserved histidine in Group-1 influenza subtype hemagglutinin proteins is essential for membrane fusion activity. Virology. 2019 Aug 6;536:78-90..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Virology. 2019 Aug 6;536:78-90. (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Influenza A viruses enter host cells through the endocytic pathway, where acidification triggers conformational changes of the viral hemagglutinin (HA) to drive membrane fusion. During this process, the ...

Gouma S, Weirick M, Hensley SE. Potential antigenic mismatch of the H3N2 component of the 2019 Southern Hemisphere influenza vaccine. Clin Infect Dis. 2019 Aug 11..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Clin Infect Dis. 2019 Aug 11. (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
Here, we find that the egg-adapted H3N2 component of the 2019 Southern Hemisphere influenza vaccine elicits an antibody response in ferrets that is highly focused on antigenic site A of hemagglutinin. ...

Ge Y, et al. The evolution and characterization of influenza A(H7N9) virus under the selective pressure of peramivir. Virology. 2019 Aug 6;536:58-67..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Virology. 2019 Aug 6;536:58-67. (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Human infection with H7N9 virus has provoked global public health concern due to the substantial morbidity and mortality. Neuraminidase inhibitors (NAIs) are used as first-line drugs to treat the infection. ...

Garvey MI, et al. Lessons learnt from influenza POCT implementation in an AMU. J Hosp Infect. 2019 Aug 6.  Abstract  
submitted by kickingbird at Aug, 15, 2019 from J Hosp Infect. 2019 Aug 6 (via https://www.journalofhospitalinfection.com/article/S0195-670)
Influenza point of care tests (POCT) can speed up diagnosis and improve management of patients with influenza.1-3 Young et al discussed the impact of a POCT for influenza in an emergency department.4 The ...

Van Bennekom CM, Kerr SM, Mitchell AA. Oseltamivir exposure in pregnancy and the risk of specific birth defects. Birth Defects Res. 2019 Aug 8.  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Birth Defects Res. 2019 Aug 8 (via https://onlinelibrary.wiley.com/doi/abs/10.1002/bdr2.1563)
BACKGROUND: Influenza during pregnancy contributes to maternal morbidity and mortality. Neuraminidase inhibitors, including oseltamivir, are recommended for treating women with influenza during pregnancy.METHODS: ...

Chambers CD, et al. Oseltamivir use in pregnancy: Risk of birth defects, preterm delivery, and small for gestational age infants. Birth Defects Res. 2019 Aug 8.  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Birth Defects Res. 2019 Aug 8 (via https://onlinelibrary.wiley.com/doi/abs/10.1002/bdr2.1566)
BACKGROUND: Influenza infection during pregnancy increases risks for adverse outcomes for both mother and fetus. For this reason, treatment for infection or postexposure prophylaxis with a neuraminidase ...

Chang KH, et al. Gulllain-Barre Syndrome After Trivalent Influenza Vaccination in Adults. Front Neurol. 2019 Jul 24;10:768..  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Front Neurol. 2019 Jul 24;10:768. (via https://www.frontiersin.org/articles/10.3389/fneur.2019.0076)
Lines of evidence suggest trivalent influenza vaccination may be associated with Guillain-Barre syndrome (GBS), an immune-mediated acute inflammatory neuropathy. On the other hand, this vaccination protects ...

Chang J, et al. octoFLU: Automated Classification for the Evolutionary Origin of Influenza A Virus Gene Sequences Detected in U.S. Swine. Microbiol Resour Announc. 2019 Aug 8;8(32)..  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Microbiol Resour Announc. 2019 Aug 8;8(32). (via https://mra.asm.org/content/8/32/e00673-19)
The diversity of the 8 genes of influenza A viruses (IAV) in swine reflects introductions from nonswine hosts and subsequent antigenic drift and shift. Here, we curated a data set and present a pipeline ...

Palekar R, et al. Patterns of influenza B circulation in Latin America and the Caribbean, 2010~2017. PLoS One. 2019 Aug 8;14(8):e0219595.  Abstract  
submitted by kickingbird at Aug, 11, 2019 from PLoS One. 2019 Aug 8;14(8):e0219595 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
OBJECTIVE: There are limited published data about the circulation of influenza B/Victoria and B/Yamagata in Latin America and the Caribbean (LAC) and most countries have a vaccine policy that includes ...

Nelson SW, et al. Madin-Darby canine kidney cell sialic acid receptor modulation induced by culture medium conditions: Implications for the isolation of influenza A virus. Influenza Other Respir Viruses. 2019 Aug 7.  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Influenza Other Respir Viruses. 2019 Aug 7 (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12671)
BACKGROUND: The influenza A virus (IAV) binds to α-2,3- and α-2,6-linked sialic acid (SA) receptors expressed by Madin-Darby canine kidney (MDCK) cells. The receptor distribution may therefore be important ...

Limburg H, et al. TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes. J Virol. 2019 Aug 7.  Abstract  
submitted by kickingbird at Aug, 11, 2019 from J Virol. 2019 Aug 7 (via https://jvi.asm.org/content/early/2019/08/05/JVI.00649-19)
Cleavage of influenza virus hemagglutinin (HA) by host cell proteases is essential for virus infectivity and spread. We previously demonstrated in vitro that the transmembrane protease TMPRSS2 cleaves ...

Jha A, et al. Patterns of systemic and local inflammation in patients with asthma hospitalised with influenza. Eur Respir J. 2019 Aug 7..  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Eur Respir J. 2019 Aug 7. (via https://erj.ersjournals.com/content/early/2019/07/31/1399300)
BACKGROUND: Patients with asthma are at risk of hospitalisation with influenza, but the reasons for this predisposition are unknown.STUDY SETTING: A prospective observational study of adults with PCR-confirmed ...

Jin F, et al. A Single Mutation N166D in Hemagglutinin Affects Antigenicity and Pathogenesis of H9N2 Avian Influenza Virus. Viruses. 2019 Aug 2;11(8)..  Abstract  
submitted by kickingbird at Aug, 8, 2019 from Viruses. 2019 Aug 2;11(8). (via https://www.mdpi.com/1999-4915/11/8/709)
Some immune escape mutants of H9N2 virus and the corresponding mutations in hemagglutinin (HA) have been documented, but little is known about the impact of a single mutation on the antigenicity and pathogenesis ...

Ren X, et al. Avian Influenza A Virus Polymerase Recruits Cellular RNA Helicase eIF4A3 to Promote Viral mRNA Splicing and Spliced mRNA Nuclear Export. Front Microbiol. 2019 Jul 16;10:1625..  Abstract  
submitted by kickingbird at Aug, 8, 2019 from Front Microbiol. 2019 Jul 16;10:1625. (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0162)
The influenza A virus replicates in a broad range of avian and mammalian species by hijacking cellular factors and processes. Avian influenza A viruses (AIVs) generally propagated poorly in mammalian cells, ...

Naguib MM, et al. Global patterns of avian influenza A(H7): virus evolution and zoonotic threats. FEMS Microbiol Rev. 2019 Aug 5.  Abstract  
submitted by kickingbird at Aug, 8, 2019 from FEMS Microbiol Rev. 2019 Aug 5 (via https://academic.oup.com/femsre/advance-article/doi/10.1093/)
Avian influenza viruses (AIVs) continue to impose a negative impact on animal and human health worldwide. In particular, the emergence of highly pathogenic AIV H5 and, more recently, the emergence of low ...

Yang J, Wang Z, Du Y, Jia Y, Wang L, Xu S, Zhu Q. Clade 2.3.2.1 H5N1 avian influenza viruses circulate at the interface of migratory and domestic birds around Qinghai Lake in China. Vet Microbiol. 2019 Aug;235:234-242.  Abstract  
submitted by kickingbird at Aug, 8, 2019 from Vet Microbiol. 2019 Aug;235:234-242 (via https://www.sciencedirect.com/science/article/pii/S037811351)
During 2012-2015, six H5N1 avian influenza viruses were isolated from domestic birds and the environment around Qinghai Lake. Phylogenetic analysis of HA genes revealed that A/chicken/Gansu/XG2/2012 (CK/GS/XG2/12) ...

Tzeng TT, et al. The stability and immunogenicity of inactivated MDCK cell-derived influenza H7N9 viruses. Vaccine. 2019 Aug 2.  Abstract  
submitted by kickingbird at Aug, 8, 2019 from Vaccine. 2019 Aug 2 (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
In recent years, cell-based influenza vaccines have gained a great interest over the egg-based vaccines. Several inactivated H7N9 vaccines have been evaluated in clinical trials, including whole-virion ...

Yang J, Müller NF, Bouckaert R, Xu B, Drummond AJ. Bayesian phylodynamics of avian influenza A virus H9N2 in Asia with time-dependent predictors of migration. PLoS Comput Biol. 2019 Aug 6;15(8):e1007189..  Abstract  
submitted by kickingbird at Aug, 8, 2019 from PLoS Comput Biol. 2019 Aug 6;15(8):e1007189. (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Model-based phylodynamic approaches recently employed generalized linear models (GLMs) to uncover potential predictors of viral spread. Very recently some of these models have allowed both the predictors ...

Liu J, et al. Genetic characterization of influenza A virus and assessment of vaccine efficacy in Yantai from 2014 to 2017. Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Aug 6;53(8):8.  Abstract  
submitted by kickingbird at Aug, 8, 2019 from Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Aug 6;53(8):8 (via https://www.ncbi.nlm.nih.gov/pubmed/31378046)
In this study, the swabs were collected among patients with an influenza-like illness (ILI) admitted to 2 sentinel surveillance hospitals of Yantai from April 2014 to August 2017. All specimen were cultured ...

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