Si L, Shen Q, Li J, Chen L, Shen J, Xiao X, Bai H,. Generation of a live attenuated influenza A vaccine by proteolysis targeting. Nat Biotechnol. 2022 Jul 4. Abstract submitted by kickingbird at Jul, 7, 2022 from Nat Biotechnol. 2022 Jul 4 (via https://www.nature.com/articles/s41587-022-01381-4) The usefulness of live attenuated virus vaccines has been limited by suboptimal immunogenicity, safety concerns or cumbersome manufacturing processes and techniques. Here we describe the generation of ... Kakuya F, Okubo H, Fujiyasu H, Kurisawa MJ, Kinebu. Clinical effectiveness of baloxavir marboxil against influenza in three seasons. Pediatr Int. 2022 Jan;64(1):e15169.. Abstract submitted by kickingbird at Jul, 7, 2022 from Pediatr Int. 2022 Jan;64(1):e15169. (via https://onlinelibrary.wiley.com/doi/10.1111/ped.15169) Background: Previous reports have not clarified the difference in clinical efficacy between baloxavir and oseltamivir against influenza.Methods: A prospective observational study was performed during 2017-2018, ... Jamoussi A, Ayed S, Merhabene T, Doghri H, Ben Khe. Severe influenza A in a Tunisian ICU sentinel SARI centre: Epidemiological and clinical features. PLoS One. 2022 Jul 6;17(7):e0270814.. Abstract submitted by kickingbird at Jul, 7, 2022 from PLoS One. 2022 Jul 6;17(7):e0270814. (via https://journals.plos.org/plosone/article?id=10.1371/journal) Introduction: Influenza A virus infection is a contagious acute respiratory infection which mostly evolves in an epidemic form, less frequently as pandemic outbreaks. It can take a severe clinical form ... Wang C, Qu R, Zong Y, Qin C, Liu L, Gao X, Sun H,. Enhanced stability of M1 protein mediated by a phospho-resistant mutation promotes the replication of prevailing avian influenza virus in mammals. PLoS Pathog. 2022 Jul 6;18(7):e1010645.. Abstract submitted by kickingbird at Jul, 7, 2022 from PLoS Pathog. 2022 Jul 6;18(7):e1010645. (via https://journals.plos.org/plospathogens/article?id=10.1371/j) Avian influenza virus (AIV) can evolve multiple strategies to combat host antiviral defenses and establish efficient infectivity in mammals, including humans. H9N2 AIV and its reassortants (such as H5N6 ... Ding L, Chen Y, Su N, Xu X, Yin J, Qiu J, Wang J,. Comparison of acute respiratory distress syndrome in patients with COVID-19 and influenza A (H7N9) virus infection. Int J Infect Dis. 2022 Jul 3:S1201-9712(22)00387-3. Abstract submitted by kickingbird at Jul, 7, 2022 from Int J Infect Dis. 2022 Jul 3:S1201-9712(22)00387-3 (via https://www.ijidonline.com/article/S1201-9712(22)00387-3/ful) Objectives: We aimed to compared the clinical features of acute respiratory distress syndrome (ARDS) induced by COVID-19 and H7N9 virus infections.Methods: Clinical data of 100 COVID-19 patients and 46 ... Rattanaburi S, Sawaswong V, Nimsamer P, Mayuramart. Genome characterization and mutation analysis of human influenza A virus in Thailand. Genomics Inform. 2022 Jun;20(2):e21. Abstract submitted by kickingbird at Jul, 7, 2022 from Genomics Inform. 2022 Jun;20(2):e21 (via https://genominfo.org/journal/view.php?doi=10.5808/gi.21077) The influenza A viruses have high mutation rates and cause a serious health problem worldwide. Therefore, this study focused on genome characterization of the viruses isolated from Thai patients based ... Wen F, Zhang X, Guo J, Liang Z, Cheng Q, Wang C, Y. Emergence of H3N8 avian influenza viruses possessing tri-basic hemagglutinin cleavage sites in China. J Infect. 2022 Jul 1:S0163-4453(22)00383-8. Abstract submitted by kickingbird at Jul, 6, 2022 from J Infect. 2022 Jul 1:S0163-4453(22)00383-8 (via https://www.journalofinfection.com/article/S0163-4453(22)003) Recently, the first human case of acute respiratory distress syndrome caused by the H3N8 subtype avian influenza virus (AIV) (A/Henan/4-10CNIC/2022, Henan4-10) was documented in this journal. The H3N8 ... Niu X, Wang H, Zhao L, Lian P, Bai Y, Li J, Qiao J. All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice. Virol J. 2022 Jun 28;19(1):113. Abstract submitted by kickingbird at Jul, 1, 2022 from Virol J. 2022 Jun 28;19(1):113 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-) Background: The H9N2 virus can infect not only birds but also humans. The pathogenicity of H9N2 virus infection is determined by an excessive immune response in the lung. All-trans retinoic acid (ATRA), ... Neveau MN, Zeller MA, Kaplan BS, Souza CK, Gauger. Genetic and Antigenic Characterization of an Expanding H3 Influenza A Virus Clade in U.S. Swine Visualized by Nextstrain. mSphere. 2022 Jun 29;7(3):e0099421. Abstract submitted by kickingbird at Jul, 1, 2022 from mSphere. 2022 Jun 29;7(3):e0099421 (via https://journals.asm.org/doi/10.1128/msphere.00994-21) Defining factors that influence spatial and temporal patterns of influenza A virus (IAV) is essential to inform vaccine strain selection and strategies to reduce the spread of potentially zoonotic swine-origin ... Subbiah J, Oh J, Kim KH, Shin CH, Park BR, Bhatnag. A chimeric thermostable M2e and H3 stalk-based universal influenza A virus vaccine. NPJ Vaccines. 2022 Jun 29;7(1):68. Abstract submitted by kickingbird at Jul, 1, 2022 from NPJ Vaccines. 2022 Jun 29;7(1):68 (via https://www.nature.com/articles/s41541-022-00498-6) We developed a new chimeric M2e and H3 hemagglutinin (HA) stalk protein vaccine (M2e-H3 stalk) by genetic engineering of modified H3 stalk domain conjugated with conserved M2e epitopes to overcome the ... Huang WJ, Cheng YH, Tan MJ, Liu J, Li XY, Zeng XX,. Epidemiological and virological surveillance of influenza viruses in China during 2020-2021. Infect Dis Poverty. 2022 Jun 29;11(1):74. Abstract submitted by kickingbird at Jul, 1, 2022 from Infect Dis Poverty. 2022 Jun 29;11(1):74 (via https://idpjournal.biomedcentral.com/articles/10.1186/s40249) Background: During the coronavirus disease 2019 (COVID-19) pandemic, seasonal influenza activity declined globally and remained below previous seasonal levels, but intensified in China since 2021. Preventive ... Sewald K, Danov O. Infection of Human Precision-Cut Lung Slices with the Influenza Virus. Methods Mol Biol. 2022;2506:119-134. Abstract submitted by kickingbird at Jul, 1, 2022 from Methods Mol Biol. 2022;2506:119-134 (via https://link.springer.com/protocol/10.1007/978-1-0716-2364-0) Viral infections are common causes of asthma exacerbations. To model these processes ex vivo, human precision-cut lung slices (PCLSs) can be used. Here we describe the infection of human PCLSs with the ... Zhang S, Sun Z, He J, Li Z, Han L, Jing S, Hao Y. The influences of the East Asian Monsoon on the spatio-temporal pattern of seasonal influenza activity in China. Sci Total Environ. 2022 Jun 27:157024. Abstract submitted by kickingbird at Jul, 1, 2022 from Sci Total Environ. 2022 Jun 27:157024 (via https://www.sciencedirect.com/science/article/abs/pii/S00489) Previous research has extensively studied the seasonalities of human influenza infections and the effect of specific climatic factors in different regions. However, there is limited understanding of the ... Hennig C, Graaf A, Petric PP, Graf L, Schwemmle M,. Are pigs overestimated as a source of zoonotic influenza viruses?. Porcine Health Manag. 2022 Jun 30;8(1):30. Abstract submitted by kickingbird at Jul, 1, 2022 from Porcine Health Manag. 2022 Jun 30;8(1):30 (via https://porcinehealthmanagement.biomedcentral.com/articles/1) Background: Swine influenza caused by influenza A viruses (IAV) directly affects respiratory health and indirectly impairs reproduction rates in pigs causing production losses. In Europe, and elsewhere, ... Dai H, Zhou N, Chen M, Li G, Yu X, Su Y, Yi S, Hon. Assess transmissibility of different influenza subtypes: Based on a SEIABR model. Infect Genet Evol. 2022 Jun 22:105319. Abstract submitted by kickingbird at Jun, 27, 2022 from Infect Genet Evol. 2022 Jun 22:105319 (via https://www.sciencedirect.com/science/article/pii/S156713482) Objective: Influenza is a worldwide public health problem which causes a serious economic and health burden. In order to provide a scientific basis for improving the prevention and control level of influenza, ... Zhang J, Ye H, Liu Y, Liao M, Qi W. Resurgence of H5N6 avian influenza virus in 2021 poses new threat to public health. Lancet Microbe. 2022 Jun 21:S2666-5247(22)00148-3. Abstract submitted by kickingbird at Jun, 27, 2022 from Lancet Microbe. 2022 Jun 21:S2666-5247(22)00148-3 (via https://www.thelancet.com/journals/lanmic/article/PIIS2666-5) First identified as belonging to the H5N1 subtype in Guangdong province, China, in 1996, the Gs/GD lineage H5 avian influenza viruses have continuously evolved and spread since. H5 subtype viruses evolved ... Ertesv?g NU, Cox RJ, Lartey SL, Mohn KG, Brokstad. Seasonal influenza vaccination expands hemagglutinin-specific antibody breadth to older and future A/H3N2 viruses. NPJ Vaccines. 2022 Jun 24;7(1):67. Abstract submitted by kickingbird at Jun, 27, 2022 from NPJ Vaccines. 2022 Jun 24;7(1):67 (via https://www.nature.com/articles/s41541-022-00490-0) History of influenza A/H3N2 exposure, especially childhood infection, shape antibody responses after influenza vaccination and infection, but have not been extensively studied. We investigated the breadth ... Guan M, Jacobson O, Sarafianos G, Baroch J, Delibe. Exposure of white-tailed deer in North America to influenza D virus. Virology. 2022 Jun 17;573:111-117. Abstract submitted by kickingbird at Jun, 27, 2022 from Virology. 2022 Jun 17;573:111-117 (via https://www.sciencedirect.com/science/article/abs/pii/S00426) Influenza D virus (IDV) infections have been identified worldwide in cattle, swine, camelid, and small ruminants, mostly in domestic livestock. Here we report that the wild white-tailed deer in North America ... Ding L, Li J, Li X, Qu B. Evolutionary and Mutational Characterization of the First H5N8 Subtype Influenza A Virus in Humans. Pathogens. 2022 Jun 8;11(6):666. Abstract submitted by kickingbird at Jun, 25, 2022 from Pathogens. 2022 Jun 8;11(6):666 (via https://www.mdpi.com/2076-0817/11/6/666) Highly pathogenic influenza A virus H5 subtype remains a risk for transmission in humans. The H5N8 subtype has caused multiple outbreaks in poultry in Europe over the past few winters. During one recent ... Yuan Z, Zhou T, Zhang J, Zeng Q, Jiang D, Wei M, L. The Genomic Evolution and the Transmission Dynamics of H6N2 Avian Influenza A Viruses in Southern China. Viruses. 2022 May 26;14(6):1154. Abstract submitted by kickingbird at Jun, 25, 2022 from Viruses. 2022 May 26;14(6):1154 (via https://www.mdpi.com/1999-4915/14/6/1154) In China, the broad prevalence of H6 subtype influenza viruses, increasingly detected in aquatic birds, promotes their exchange materials with other highly pathogenic human-infecting H5N1, H5N6, and H7N9 ... 9877 items, 20/Page, Page[174/494][|<<] [|<] [171] [172] [173] [174] [175] [176] [177] [178] [179] [180] [>|] [>>|] |
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