Li W, Shi Y, Li D, Wang Y, Sun Y, Li H, Han Y. A CRISPR Powered Immobilization-Free, Amplification-Free Carbon-Nanotube Field-Effect Transistor (FET) Sensor for Influenza A Virus (IAV). Molecules. 2025; 30(23):4608. Abstract
submitted by kickingbird at 4 days ago from Molecules. 2025; 30(23):4608 (via https://www.mdpi.com/1420-3049/30/23/4608)
The epidemic of infectious diseases, such as influenza A, has imposed a severe health burden on the population. Early detection, diagnosis, reporting, isolation, and treatment are crucial for the prevention, ... Ziqin Song, etc.,al. Dual signal amplification strategy: CRISPR/Cas9 trans-cleavage combined with strand displacement amplification for influenza virus detection. Microchemical Journal. Abstract
submitted by kickingbird at 5 days ago from Microchemical Journal (via https://www.sciencedirect.com/science/article/abs/pii/S00262)
The core effector protein, Cas9 of the CRISPR/Cas9 system is capable of recognizing and cleaving target DNA sequences under the guidance of guide RNA (gRNA). This study developed a novel platform for detecting ... Hatta, M., Brock, N., Hauguel, T. et al. Influenza mRNA vaccine reduces pathogenicity and transmission of A(H5N1) virus in a ferret model. npj Vaccines (2025). Abstract
submitted by kickingbird at 5 days ago from npj Vaccines (2025) (via https://link.springer.com/article/10.1038/s41541-025-01318-3)
The global spread of highly pathogenic avian influenza A(H5N1) viruses poses a serious pandemic threat. While sustained human-to-human transmission has not occurred, widespread circulation in birds, increased ... Wu M, Wang M, Zeng X, Zhang K, Wang M, Xu G, Wang. HA protein acetylation modulates replication, pathogenicity, and immunogenicity of influenza virus and facilitates live-attenuated vaccine design. Emerg Microbes Infect. 2025 Nov 27:2595799. Abstract
submitted by kickingbird at 7 days ago from Emerg Microbes Infect. 2025 Nov 27:2595799 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Lysine acetylation, a form of protein post-translational modifications (PTM), is known to play crucial roles in regulating cellular and physiological processes. In this study, for the first time, lysine ... Lucas F. de Lima, etc.,al. High Throughput Influenza A Virus Detection by Isothermal Amplification in Sequential-Injection Paper-Based Microfluidics. Biosensors and Bioelectronics. Abstract
submitted by kickingbird at 14 days ago from Biosensors and Bioelectronics (via https://www.sciencedirect.com/science/article/abs/pii/S09565)
The recognized impact of epidemics and pandemics caused by Influenza A virus highlights the need for rapid, sensitive, and accessible diagnostic methods. In this work, we propose a molecular detection ... Ping Wang, Han Wu, Jiamin Fu, etc.,al. Rapid and sensitive time-resolved fluorescence immunochromatographic strip for detecting H10 subtype avian influenza virus. Poultry Science, Vol 105, Issue 1, January 2026,. Abstract
submitted by kickingbird at 14 days ago from Poultry Science, Vol 105, Issue 1, January 2026, (via https://www.sciencedirect.com/science/article/pii/S003257912)
Human infections with the H10 subtype avian influenza virus (AIV) have been reported in recent years, raising concern about potential human-to-human transmission. Effective field detection methods are ... Fitz-Patrick D, McVinnie DS, Jackson LA, Crowther. Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine. N Engl J Med. 2025 Nov 20;393(20):2001-2011. Abstract
submitted by kickingbird at 14 days ago from N Engl J Med. 2025 Nov 20;393(20):2001-2011 (via https://www.nejm.org/doi/10.1056/NEJMoa2416779)
Background: Influenza remains a major health burden despite the use of licensed vaccines. Nucleoside-modified messenger RNA (modRNA) influenza vaccines have shown promising immunogenicity against influenza ... Naito T, Ushirogawa H, Kunishio M, Yano H, Saito S. Live-attenuated influenza virus vaccine strain with an engineered temperature-sensitive and genetically stable viral polymerase variant. J Virol 0:e01390-25. Abstract
submitted by kickingbird at 15 days ago from J Virol 0:e01390-25 (via https://journals.asm.org/doi/10.1128/jvi.01390-25)
Vaccination against seasonal influenza is considered an effective means of reducing morbidity and mortality. Live-attenuated vaccines offer more protection against influenza than inactivated vaccines as ... Llewellyn, S., Schewe, K.E., Ayaz, S. et al. Replication in human cells supersedes serum antigenic match for the in vivo efficacy of an A/H1N1pdm09 LAIV virus. NPJ Vaccines. 2025 Nov 17;10(1):236. Abstract
submitted by kickingbird at Nov, 19, 2025 from NPJ Vaccines. 2025 Nov 17;10(1):236 (via https://www.nature.com/articles/s41541-025-01281-z)
For FluMist?/Fluenz live attenuated influenza vaccine (LAIV), efficient virus replication in human nasal epithelial cells (hNEC) is an important factor in vaccine effectiveness (VE). The necessity of antigenic ... Zhen Wan, Haijiang Gong, Qi Liu, etc.,al. Fluorescence/Colorimetric Lateral Flow Immunoassay Based on Dual-Aptamer Domain Recognition and Upconversion Signal Amplification for Sensitive H1N1 Hemagglutinin Detection. Advanced Functional Materials. Abstract
submitted by kickingbird at Nov, 17, 2025 from Advanced Functional Materials (via https://advanced.onlinelibrary.wiley.com/doi/10.1002/adfm.20)
Rapid and specific detection of influenza A viruses is critical for pandemic response. However, traditional lateral flow immunoassays (LFIAs) face challenges in sensitivity, signal reliability, and cross-reactivity. ... Entriken CG, Bruce KL, Coyne BM, Kruyer SH, Sincla. Improved efficacy of an influenza DNA vaccine through high-density microarray patch delivery. J Gen Virol. 2025 Nov;106(11):002179. Abstract
submitted by kickingbird at Nov, 16, 2025 from J Gen Virol. 2025 Nov;106(11):002179 (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Pandemic preparedness requires vaccine platforms that are fast to produce, thermostable and suitable for broad deployment. DNA vaccines are well suited to this task but have historically suffered from ... Qadir MF, Yang Y. Overcoming Challenges in Avian Influenza Diagnosis: The Role of Surface-Enhanced Raman Spectroscopy in Poultry Health Monitoring. Veterinary Sciences. 2025; 12(11):1052. Abstract
submitted by kickingbird at Nov, 2, 2025 from Veterinary Sciences. 2025; 12(11):1052 (via https://www.mdpi.com/2306-7381/12/11/1052)
Rapid and accurate diagnostics for influenza viruses are essential for preventing future epidemics. Surface-enhanced Raman spectroscopy (SERS) presents a promising alternative to conventional techniques, ... Stadler, J., Grau, K., Lillie-Jaschniski, K. et al. Diagnostic performance of ELISA kits and expanded antigen panels for hemagglutination inhibition assays in pig herds enzootically infected with porcine Influenza A viruses. Porc Health Manag 11, 53 (2025). Abstract
submitted by kickingbird at Nov, 2, 2025 from Porc Health Manag 11, 53 (2025) (via https://link.springer.com/article/10.1186/s40813-025-00464-3)
BackgroundA combined approach using both indirect and direct detection methods can improve the diagnostic efficiency of swine Influenza A virus (swIAV) infections. Despite its importance, limited research ... Abdullatif, T.M., Hassanin, O., Mohamed, W. et al. Investigation into the efficacy of a commercially available inactivated avian influenza virus (AIV) vaccine (H9N2) through experimental and field assessments, with an emphasis on its compatibility wit. Vet Res Commun 50, 14 (2026). Abstract
submitted by kickingbird at Nov, 2, 2025 from Vet Res Commun 50, 14 (2026) (via https://link.springer.com/article/10.1007/s11259-025-10919-1)
Avian influenza H9N2 virus has established itself as endemic in various parts of the globe notably in the Middle East with significant economic repercussions. Vaccination with inactivated vaccine is regarded ... M. Salines, etc.,al. To what extent may the duck population be protected after vaccination against highly pathogenic avian influenza? Contributions from a modelling approach and French field data. Vaccine, Volume 68, 5 December 2025, 127905. Abstract
submitted by kickingbird at Nov, 2, 2025 from Vaccine, Volume 68, 5 December 2025, 127905 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
Faced with increasingly disastrous avian influenza crises, and considering the associated zoonotic risk, France launched a vaccination campaign against highly pathogenic avian influenza on duck farms with ... Wu, M., Wang, P., Wang, L. et al. Live attenuated influenza vaccine with low proportions of defective interfering particles elicits robust immunogenicity and cross-protection. Nat Commun 16, 9647 (2025). Abstract
submitted by kickingbird at Nov, 2, 2025 from Nat Commun 16, 9647 (2025) (via https://www.nature.com/articles/s41467-025-64651-0)
Commercial live attenuated influenza vaccines (LAIVs) usually contain a high proportion of defective interfering particles (DIPs). Given that LAIVs are not sufficiently protective worldwide, the potential ... Stadler, J., Grau, K., Lillie-Jaschniski, K. et al. Diagnostic performance of ELISA kits and expanded antigen panels for hemagglutination inhibition assays in pig herds enzootically infected with porcine Influenza A viruses. Porc Health Manag 11, 53 (2025). Abstract
submitted by kickingbird at Oct, 28, 2025 from Porc Health Manag 11, 53 (2025) (via https://link.springer.com/article/10.1186/s40813-025-00464-3)
BackgroundA combined approach using both indirect and direct detection methods can improve the diagnostic efficiency of swine Influenza A virus (swIAV) infections. Despite its importance, limited research ... Zhao L, Huang Z, Long W. China’s Invisible Chicken Losses: Production Costs Effect of Highly Pathogenic Avian Influenza. Agriculture. 2025; 15(20):2176. Abstract
submitted by kickingbird at Oct, 22, 2025 from Agriculture. 2025; 15(20):2176 (via https://www.mdpi.com/2077-0472/15/20/2176)
Highly pathogenic avian influenza (HPAI) affects chicken production not only during outbreaks but also afterward. Understanding its delayed effect is essential for facilitating timely production recovery. ... Bacsik DJ, Mills MG, Monroe LD, Spring C, Perez-Os. Validation of H5 influenza virus subtyping RT-qPCR assay and low prevalence of H5 detection in 2024-2025 influenza virus season. J Clin Microbiol. 2025 Oct 21:e0041525. Abstract
submitted by kickingbird at Oct, 22, 2025 from J Clin Microbiol. 2025 Oct 21:e0041525 (via https://journals.asm.org/doi/10.1128/jcm.00415-25)
A sustained outbreak of H5N1 influenza virus among wild fowl and domestic livestock has caused more than 70 zoonotic infections in humans in North America, including two deaths. The United States Centers ... Kok, A., Wilks, S.H., Tureli, S. et al. A vaccine central in A(H5) influenza antigenic space confers broad immunity. Nature (2025). Abstract
submitted by kickingbird at Oct, 16, 2025 from Nature (2025) (via https://link.springer.com/article/10.1038/s41586-025-09626-3)
Highly pathogenic avian influenza A(H5) viruses globally impact wild and domestic birds, and have caused severe infections in mammals, including humans, underscoring their pandemic potential1,2,3,4,5. ... 279 items, 20/Page, Page[1/14][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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