Ga, E., Xie, X., Hwang, J. et al. Host-specific effects of a pandemic H1N1 M gene on canine H3N2 influenza virus replication and immune responses. Sci Rep (2026). Abstract submitted by kickingbird at 2 days ago from Sci Rep (2026) (via https://link.springer.com/article/10.1038/s41598-026-70452-2) The emergence of novel influenza strains through reverse-zoonotic transmission poses potential risks to both animal and human health. This study characterized a naturally isolated reassortant canine H3N2 ... Wan Z, Jiang W, Cao X, Guo X, He X, Zhang J, Chu X. Novel emerging reassortant H6 avian influenza viruses with internal genes from G57 genotype of H9N2 pose potential zoonotic risk. Emerg Microbes Infect. 2026 Dec;15(1):2732846. Abstract submitted by kickingbird at 2 days ago from Emerg Microbes Infect. 2026 Dec;15(1):2732846 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2) In recent decades, multiple novel reassortant avian influenza viruses (AIVs) carrying internal genes derived from H9N2 viruses have emerged in poultry in China and have repeatedly caused human infections, ... Fan, M., Liu, Z., Deng, L. et al. LncFENIX restricts influenza A virus replication by impairing PDIA3-mediated oxidative folding of hemagglutinin. Cell Commun Signal (2026). Abstract submitted by kickingbird at 3 days ago from Cell Commun Signal (2026) (via https://link.springer.com/article/10.1186/s12964-026-03228-w) BackgroundInfluenza A virus (IAV) relies on host endoplasmic reticulum (ER) homeostasis machinery to support the oxidative folding and maturation of viral glycoproteins. Although long non-coding RNAs (lncRNAs) ... Seibert, B.A., Parish, M.A., Talukdar, S.N. et al. Trimester-dependent vertical transmission of H5N1 influenza virus through placental and mammary routes impairs offspring development. Nat Commun 17, 9968 (2026). Abstract submitted by kickingbird at 3 days ago from Nat Commun 17, 9968 (2026) (via https://www.nature.com/articles/s41467-026-76891-9) Avian influenza H5N1 has pandemic potential and historically causes more severe disease in pregnant women than the general population. With increasing transmission of H5N1 detected among placental mammals, ... Caroline Kikawa, etc.,al. [preprint]Near real-time data on the human neutralizing antibody landscape to influenza virus in summer of 2026 shows antigenic advance of H3N2 subclade K region D mutants and H1N1 D.3.1.1 Sa mutants. https://doi.org/10.64898/2026.09.15.751855. Abstract submitted by kickingbird at 3 days ago from https://doi.org/10.64898/2026.09.15.751855 (via https://www.biorxiv.org/content/10.64898/2026.09.15.751855v1) Human seasonal influenza evolves rapidly, necessitating twice yearly decisions about whether to update the strains in the vaccine. To help inform this decision, we have been using high-throughput sequencing-based ... de Araujo J, Thomazelli LM, Fabrizio TP, Fenner GO. Detection of Divergent Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus, Sao Paulo, Brazil, 2025. Emerg Infect Dis. 2026 Oct. Abstract submitted by kickingbird at 4 days ago from Emerg Infect Dis. 2026 Oct (via https://wwwnc.cdc.gov/eid/article/32/10/26-0723_article) In 2025, we detected highly pathogenic avian influenza H5N1 virus in dead waterfowl at Ibirapuera Park, S?o Paulo, Brazil. Genomic characterization indicated a reassortant virus that emerged from locally ... Sch?n J, Breithaupt A, Halwe NJ, Hertel M, Ahrens. Experimental Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Alpacas, 2026. Emerg Infect Dis. 2026 Oct. Abstract submitted by kickingbird at 4 days ago from Emerg Infect Dis. 2026 Oct (via https://wwwnc.cdc.gov/eid/article/32/10/26-0491_article) Highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b virus continues to spread globally and sporadically transmits from avian reservoirs to mammalian hosts. In May 2024, H5N1 infections in young ... Byrne AMP, Carnegie L, Lewis NS, Barr IG, Karlsson. Reassortment of Highly Pathogenic Avian Influenza as a Driver for Zoonotic Spillover, Asia. Emerg Infect Dis. 2026 Oct. Abstract submitted by kickingbird at 4 days ago from Emerg Infect Dis. 2026 Oct (via https://wwwnc.cdc.gov/eid/article/32/10/26-0067_article) Highly pathogenic avian influenza H5Nx viruses remain a major zoonotic threat, yet global attention has focused largely on clade 2.3.4.4b, potentially overlooking major changes within long-endemic H5N1 ... Yang J, Chen C, Zhang Z, Li J, Cui W, Jiang Y, Wan. Genetic Characteristics and Pathogenicity of Recent G4 Eurasian Avian-like H1N1 Swine Influenza Viruses in China. Veterinary Sciences. 2026; 13(9):936. Abstract submitted by kickingbird at 4 days ago from Veterinary Sciences. 2026; 13(9):936 (via https://www.mdpi.com/2306-7381/13/9/936) G4 Eurasian avian-like H1N1 (G4 EA-H1N1) swine influenza viruses continue to be detected in pigs in China and remain a concern because of their reassortant genomes and zoonotic potential. Here, six H1N1 ... Gabiden A, Mutaliyeva A, Usserbayev A, Yermekbayev. Antigenic and Molecular Genetic Evolution of Influenza Viruses in Kazakhstan from 2017 to 2025. Biology. 2026; 15(18):1640. Abstract submitted by kickingbird at 4 days ago from Biology. 2026; 15(18):1640 (via https://www.mdpi.com/2079-7737/15/18/1640) Influenza viruses continuously evolve, which can change their circulation patterns and reduce recognition by existing immunity and vaccine-induced antibodies. Continuous surveillance is therefore important ... Antoni Wrobel, etc.,al. [preprint]H18 haemagglutinin binds MHC class II at a site distant from the canonical sialic-acid binding site. https://doi.org/10.21203/rs.3.rs-10549591/v1. Abstract submitted by kickingbird at 4 days ago from https://doi.org/10.21203/rs.3.rs-10549591/v1 (via https://www.researchsquare.com/article/rs-10549591/v1) Influenza virus haemagglutinin (HA) binds sialic-acid receptors to mediate cell entry of canonical influenza A viruses (IAVs) and is a key determinant of viral tropism and host range. However, the bat-derived ... Alanis Silva Melgarejo, etc.,al. [preprint]Highly Pathogenic Avian Influenza Clade 2.3.4.4b in Antarctic Pinnipeds: first evidences of virus circulation in Weddell seals. https://doi.org/10.21203/rs.3.rs-10922875/v1. Abstract submitted by kickingbird at 4 days ago from https://doi.org/10.21203/rs.3.rs-10922875/v1 (via https://www.researchsquare.com/article/rs-10922875/v1) The ongoing expansion of highly pathogenic avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b has resulted in unprecedented outbreaks among wild birds and marine mammals, raising concerns about viral dissemination ... Juliane Lang, etc.,al. [preprint]Compensatory Mutations in Avian Influenza H7N1 Hemagglutinin Drive Avian Host Adaptation and Antigenic Drift without Enhancing Replication in Human Cells. https://doi.org/10.21203/rs.3.rs-10351951/v1. Abstract submitted by kickingbird at 4 days ago from https://doi.org/10.21203/rs.3.rs-10351951/v1 (via https://www.researchsquare.com/article/rs-10351951/v1) Avian influenza A viruses (AIVs) of the H7 subtype have caused outbreaks in poultry and human ranging from mild to fatal disease. In Europe, H7 viruses have demonstrated an unusual capacity for prolonged ... Ross RA, Walsh SK, Montgomery H, Chen H, Hutchinso. Bovine mammary tissues are susceptible to infection by viruses bearing panzootic H5N1 influenza A virus glycoproteins. J Gen Virol. 2026 Sep;107(9). Abstract submitted by kickingbird at 5 days ago from J Gen Virol. 2026 Sep;107(9) (via https://www.microbiologyresearch.org/content/journal/jgv/10.) The emergence of the panzootic clade 2.3.4.4b highly pathogenic H5N1 avian influenza in 2020 marked a major expansion in the host range of influenza A viruses (IAVs), raising concerns about further cross-species ... Zhao Y, Lei Y, Xu Q, Zhang S, Xie Q, Yuan L, Liang. Zbtb46T11A Mutation Is Associated with Enhanced Influenza Vaccine Immunogenicity and Altered cDC1 Proportions in Mice. Biology. 2026; 15(17):1558. Abstract submitted by kickingbird at 5 days ago from Biology. 2026; 15(17):1558 (via https://www.mdpi.com/2079-7737/15/17/1558) Background: Influenza remains a significant global public health threat, causing substantial morbidity and mortality worldwide. While vaccination serves as the best preventive strategy, considerable interindividual ... Lea Separovic, etc.,al. [preprint]2025/26 subclade-specific influenza A and B vaccine effectiveness estimates and discordant laboratory-based indicators of vaccine match or mismatch. https://doi.org/10.64898/2026.09.10.26362769. Abstract submitted by kickingbird at 6 days ago from https://doi.org/10.64898/2026.09.10.26362769 (via https://www.medrxiv.org/content/10.64898/2026.09.10.26362769) Background: The 2025/26 influenza season included A(H3N2) subclade K predominance with A(H1N1)pdm09 co-circulation and subsequent prolonged influenza B activity. The Canadian Sentinel Practitioner Surveillance ... MV Jackson, etc.,al. [preprint]Establishment of an avian influenza surveillance program in Australia’s largest river basin. https://doi.org/10.64898/2026.09.09.750291. Abstract submitted by kickingbird at 6 days ago from https://doi.org/10.64898/2026.09.09.750291 (via https://www.biorxiv.org/content/10.64898/2026.09.09.750291v1) To-date Australia has had mostly coastal occurrences in a small but growing number of species of high pathogenicity avian influenza (HPAI) H5N1 clade 2.3.4.4b. The potential impacts of expected spread ... Qi X, Rahali IS, Munier S, Badel A, Flatters D, Ca. Ensemble-Based Reconstruction and Prioritization of Binding Sites in Influenza A Nucleoprotein. J Chem Inf Model. 2026 Sep 14;66(17):11006-11023. Abstract submitted by kickingbird at 6 days ago from J Chem Inf Model. 2026 Sep 14;66(17):11006-11023 (via https://pubs.acs.org/jcisd8/article-abstract/66/17/11006/532) Influenza A nucleoprotein (NP) is essential for viral RNA binding, ribonucleoprotein assembly, and NP oligomerization, making it an attractive antiviral target; however, static structures incompletely ... Guo F, Zhang P, He G, Ho KF, Tian L.. Ambient ozone reduces influenza activity in Hong Kong with effect moderated by epidemic phase. Ecotoxicol Environ Saf. 2026 Sep 12;323:120791. Abstract submitted by kickingbird at 6 days ago from Ecotoxicol Environ Saf. 2026 Sep 12;323:120791 (via https://www.sciencedirect.com/science/article/pii/S014765132) Ambient ozone (O3) has been reported to be associated with influenza activity, but evidence remains inconsistent, particularly in subtropical settings. Here, we investigated this question in subtropical ... Timm, F.C.B., Gasparetto, R., C?rrea, M.L. et al. Genomic detection of highly pathogenic avian influenza H5N1 in Antarctic seabirds reveals connectivity with South American viral lineages. Braz J Microbiol 57, 273 (2026). Abstract submitted by kickingbird at 7 days ago from Braz J Microbiol 57, 273 (2026) (via https://link.springer.com/article/10.1007/s42770-026-02076-7) Emerging avian viruses increasingly threaten Antarctic wildlife, raising concerns about ecosystem health and biodiversity. 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