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2025-7-17 23:43:08
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Krista Howden, etc.,al. Applying Field and Genomic Epidemiology Methods to Investigate Transmission Networks of Highly Pathogenic Avian Influenza A (H5N1) in Domestic Poultry in British Columbia, Canada (2022–2023). Transboundary and Emerging Diseases 2025.  Abstract  
submitted by kickingbird at 45 minute(s) ago from Transboundary and Emerging Diseases 2025 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/4099285)
Highly pathogenic avian influenza (HPAI) virus A (H5N1) was first detected in North America in 2021. Ongoing spillover events from wild to domestic birds and subsequent transmission between domestic birds ...

Wang B, Wang G, Wang Y-h, Liu X, Li M, Kong H, Che. A Strand-Specific Quantitative RT-PCR Method for Detecting vRNA, cRNA, and mRNA of H7N9 Avian Influenza Virus in a Mouse Model. Viruses. 2025; 17(7):1007.  Abstract  
submitted by kickingbird at 50 minute(s) ago from Viruses. 2025; 17(7):1007 (via https://www.mdpi.com/1999-4915/17/7/1007)
Avian influenza virus (AIV) remains a persistent threat to both the poultry industry and human health. Among the AIV subtypes posing public health threats, H7N9 AIV is responsible for five epidemic waves ...

Frye EA, Nooruzzaman M, Cronk B, Laverack M, Britt. Isolation of Highly Pathogenic Avian Influenza A(H5N1) Virus from Cat Urine after Raw Milk Ingestion, United States. Emerg Infect Dis. 2025 Aug.  Abstract  
submitted by kickingbird at 58 minute(s) ago from Emerg Infect Dis. 2025 Aug (via https://wwwnc.cdc.gov/eid/article/31/8/25-0309_article)
In 2024, 3 domestic cats in California, USA consumed raw milk contaminated with highly pathogenic avian influenza A(H5N1) virus. Fever and neurologic signs developed; 2 cats died. The surviving cat’s urine ...

Hirschinger J, H?fle U, Sánchez-Cano A, Guinat C,. Multidisciplinary Tracking of Highly Pathogenic Avian Influenza A(H5N1) Outbreak in Griffon Vultures, Southern Europe, 2022. Emerg Infect Dis. 2025 Aug.  Abstract  
submitted by kickingbird at 59 minute(s) ago from Emerg Infect Dis. 2025 Aug (via https://wwwnc.cdc.gov/eid/article/31/8/24-1456_article)
Since 2021, highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b virus has affected wild bird populations globally. Griffon vultures (Gyps fulvus), a species hitherto considered unexposed, experienced ...

De Mathia F, Kargl T, Müller M, Erdem I, Hayes B,. Purification and characterization of recombinant neuraminidase as a potentially broadly protective influenza virus vaccine candidate. Vaccine. 2025 Jul 11;62:127471.  Abstract  
submitted by kickingbird at 4 days ago from Vaccine. 2025 Jul 11;62:127471 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Influenza viruses pose a significant public health threat, causing seasonal epidemics and occasional pandemics with substantial morbidity and mortality worldwide. The development of effective vaccines ...

Khan MY, Shah AU, Duraisamy N, Cherkaoui M, Hemida. Repurposing of Some Nucleoside Analogs Targeting Some Key Proteins of the Avian H5N1 Clade 2.3.4.4b to Combat the Circulating HPAI in Birds: An In Silico Approach. Viruses. 2025; 17(7):972.  Abstract  
submitted by kickingbird at 4 days ago from Viruses. 2025; 17(7):972 (via https://www.mdpi.com/1999-4915/17/7/972)
Background: The highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b is an emerging threat that poses a great risk to the poultry industry. A few human cases have been linked to the infection with ...

Liu F, Chang J, Huang J, Liao Y, Deng X, Guo T, Ko. Surface Display of Avian H5 and H9 Hemagglutinin Antigens on Non-Genetically Modified Lactobacillus Cells for Bivalent Oral AIV Vaccine Development. Microorganisms. 2025; 13(7):1649.  Abstract  
submitted by kickingbird at 4 days ago from Microorganisms. 2025; 13(7):1649 (via https://www.mdpi.com/2076-2607/13/7/1649)
A novel bivalent oral vaccine candidate against H5N1 and H9N2 avian influenza virus (AIV) was developed using Lactobacillus surface display technology without genetic modification. The hemagglutinin subunit ...

Huang, C. Q. et al. Computationally designed haemagglutinin with nanocage plug-and-display elicits pan-H5 influenza vaccine responses. Emerging Microbes & Infections, 14(1).  Abstract  
submitted by kickingbird at 4 days ago from Emerging Microbes & Infections, 14(1) (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
The increasing spread of highly pathogenic avian influenza (HPAI) A/H5 viruses poses a pandemic threat. Circulating clade 2.3.4.4b viruses have demonstrated rapid transcontinental dissemination, extensive ...

Vasilev, K., Hoxie, I., Puente-Massaguer, E. et al. Immunogenicity and protective efficacy of an intranasal neuraminidase-based influenza vaccine with bacterial cell membrane-derived adjuvants. npj Vaccines 10, 149 (2025).  Abstract  
submitted by kickingbird at 4 days ago from npj Vaccines 10, 149 (2025) (via https://link.springer.com/article/10.1038/s41541-025-01209-7)
Development of mucosal influenza virus vaccines which protect the site of viral entry is of high importance. Recombinant neuraminidase (NA) has emerged as an antigenically conserved intranasal vaccine ...

Nemoto, M., Kawanishi, N., Kambayashi, Y. et al. Growth properties of recombinant equine influenza viruses with different backbones generated by reverse genetics in embryonated chicken eggs. Arch Virol 170, 181 (2025).  Abstract  
submitted by kickingbird at 5 days ago from Arch Virol 170, 181 (2025) (via https://link.springer.com/article/10.1007/s00705-025-06368-5)
Reverse genetics (RG) technology is useful for quickly updating influenza vaccine strains. A high-yield backbone (i.e., six segments other than hemagglutinin and neuraminidase) derived from A/Puerto Rico/8/1934 ...

Mostafa, A., Ye, C., Barre, R.S. et al. A live attenuated NS1-deficient vaccine candidate for cattle-origin influenza A (H5N1) clade 2.3.4.4.b viruses. npj Vaccines 10, 151 (2025).  Abstract  
submitted by kickingbird at 5 days ago from npj Vaccines 10, 151 (2025) (via https://link.springer.com/article/10.1038/s41541-025-01207-9)
Avian Influenza viruses (AIVs) present a public health risk, especially with seasonal vaccines offering limited protection. AIV H5N1 clade 2.3.4.4b has caused a multi-state outbreaks in the United States ...

Cunningham MW, Brown J, Hardman R, Loerzel S, Klue. Outbreaks of Highly Pathogenic H5N1 Influenza A Virus infection in Black Vultures (Coragyps atratus), USA, 2022. J Wildl Dis. 2025 Jul 11.  Abstract  
submitted by kickingbird at 6 days ago from J Wildl Dis. 2025 Jul 11 (via https://meridian.allenpress.com/jwd/article/doi/10.7589/JWD-)
Mortalities in Black Vultures (Coragyps atratus) caused by A/goose/Guangdong/1/1996 2.3.4.4b lineage highly pathogenic (HP) influenza A virus (IAV) H5N1 (HP H5N1) were detected in Florida, USA, on 14 February ...

Song Y, Zhang X, Ji J, Li L, Zhou Y, Ren G, Lv S,. Genetic characteristics analysis of influenza A(H1N1) virus in Jiaxing, China, in the postepidemic era. BMC Infect Dis. 2025 Jul 10;25(1):905.  Abstract  
submitted by kickingbird at 6 days ago from BMC Infect Dis. 2025 Jul 10;25(1):905 (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
Background: Following the lifting of COVID-19 pandemic control measures, a progressive increase in influenza A virus activity, particularly the H1N1 subtype, has been observed in Jiaxing. This study systematically ...

Mosaad Z, Hagag NM, Elsayed MM, Mady WH, Zanaty AM. Isolation, characterization and phylogenetic analyses of avian influenza A (H9N2) viruses isolated from poultry between 2019 and 2023 in Egypt. BMC Vet Res. 2025 Jul 11;21(1):455.  Abstract  
submitted by kickingbird at 6 days ago from BMC Vet Res. 2025 Jul 11;21(1):455 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
The current study aimed to investigate the genetic characterization and evolution of low pathogenic avian influenza virus H9N2 in Egypt. Ten H9N2 viruses were recently isolated from samples collected between ...

Neira V, Ariyama N, Castillo-Torres PN, Brito B, M. Genetic Characterization of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b, Antarctica, 2024. Emerg Infect Dis. 2025 Jul 9;31(8).  Abstract  
submitted by kickingbird at 7 days ago from Emerg Infect Dis. 2025 Jul 9;31(8) (via https://wwwnc.cdc.gov/eid/article/31/8/25-0186_article)
In 2024, we sequenced highly pathogenic avian influenza virus A(H5N1) clade 2.3.4.4b genomes isolated from 5 brown skuas from James Ross Island, Antarctica. Phylogenetic analysis suggested the virus reached ...

Seo YR, Cho AY, Kim DJ, Si YJ, Jeong HS, Lee SW, S. Transmission Dynamics of Highly Pathogenic Avian Influenza A(H5N1) and A(H5N6) Viruses in Wild Birds, South Korea, 2023-2024. Emerg Infect Dis. 2025 Jul 9;37(8).  Abstract  
submitted by kickingbird at 7 days ago from Emerg Infect Dis. 2025 Jul 9;37(8) (via https://wwwnc.cdc.gov/eid/article/31/8/25-0373_article)
We analyzed 15 cases of highly pathogenic avian influenza (HPAI) clade 2.3.4.4b virus infections detected in wild birds in South Korea during September 2023-March 2024. We isolated and sequenced 8 H5N1 ...

Biswas A, Eisfeld AJ, Guan L, Gu C, Wang T, Abozei. Susceptibility and shedding in Mx1+ and Mx1- female mice experimentally infected with dairy cattle A(H5N1) influenza viruses. EBioMedicine. 2025 Jul 8;118:105842.  Abstract  
submitted by kickingbird at 7 days ago from EBioMedicine. 2025 Jul 8;118:105842 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: Clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) (HPAI H5N1) viruses have spread prolifically in dairy cattle in the US, resulting in dozens of human infections, some without well-established ...

Signore AV, Giacinti J, Jones MEB, Erdelyan CNG, M. Spatiotemporal reconstruction of the North American A(H5N1) outbreak reveals successive lineage replacements by descendant reassortants. Sci Adv. 2025 Jul 11;11(28):eadu4909.  Abstract  
submitted by kickingbird at 8 days ago from Sci Adv. 2025 Jul 11;11(28):eadu4909 (via https://www.science.org/doi/10.1126/sciadv.adu4909)
The November 2021 introduction of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b into North America triggered a devastating outbreak, affecting more than 180 million domestic birds and spreading ...

Kandel S, Babujee L, Guan L, Dahn R, Pattinson D,. Phylogenetic analysis of H5N1 influenza viruses isolated from dairy cattle in Texas in December 2024. J Virol. 2025 Jul 8:e0058025.  Abstract  
submitted by kickingbird at 9 days ago from J Virol. 2025 Jul 8:e0058025 (via https://journals.asm.org/doi/10.1128/jvi.00580-25)
Highly pathogenic avian influenza (HPAI) viruses of genotype B3.13 were first reported in dairy cattle in March 2024 and, by 4 March 2025, had infected at least 989 cattle herds in 17 states in the US ...

Hao M, Wu J, Ji L, Zhao Y, Zhang S, Guan Y, Li L,. Pathogenicity, transmissibility, and receptor binding of a human-isolated influenza A (H10N5) virus. mBio. 2025 Jul 8:e0073125.  Abstract  
submitted by kickingbird at 9 days ago from mBio. 2025 Jul 8:e0073125 (via https://journals.asm.org/doi/10.1128/mbio.00731-25)
Recently, human infections with H10 influenza viruses, including H10N8 and H10N3, have been reported. In January 2024, a case of H10N5 and H3N2 co-infection was reported in Zhejiang Province, China, which ...

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