Dapat C, Peck H, Jelley L, Diefenbach-Elstob T, Sl. Extended influenza seasons in Australia and New Zealand in 2025 due to the emergence of influenza A(H3N2) subclade K viruses. Euro Surveill. 2025 Dec;30(49). Abstract
submitted by kickingbird at 6 hours ago from Euro Surveill. 2025 Dec;30(49) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
In Australia and New Zealand, late outbreaks of an A(H3N2) variant virus termed subclade K extended the 2025 influenza season. Subclade K viruses were genetically and antigenically distinct from the 2025 ... Wang, Y., Zhai, S., Wu, C. et al. Dynamic ensemble deep learning with multi-source data for robust influenza forecasting in Yangzhou. BMC Public Health (2025). Abstract
submitted by kickingbird at 6 hours ago from BMC Public Health (2025) (via https://link.springer.com/article/10.1186/s12889-025-25937-6)
Background: Traditional influenza surveillance often suffers from reporting delays, hindering timely public health response. This study aimed to mitigate this limitation by developing an accurate deep ... de Paiva Froes Rocha, R., Tomris, I., Bowman, C.A.. Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift. Nat Commun (2025). Abstract
submitted by kickingbird at 6 hours ago from Nat Commun (2025) (via https://www.nature.com/articles/s41467-025-66375-7)
The quest for a universal influenza vaccine holds great promise for mitigating the global burden of influenza-related morbidity and mortality. However, challenges persist in identifying conserved epitopes ... Vanstreels RET, Nelson MI, Artuso MC, Marchione VD. Novel Highly Pathogenic Avian Influenza A(H5N1) Virus, Argentina, 2025. Emerg Infect Dis. 2025 Dec. Abstract
submitted by kickingbird at 9 hours ago from Emerg Infect Dis. 2025 Dec (via https://wwwnc.cdc.gov/eid/article/31/12/25-0783_article)
Genomic sequencing of reemerging highly pathogenic avian influenza A(H5N1) virus detected in Argentina in February 2025 revealed novel triple-reassortant viruses containing gene segments from Eurasian ... EFSA/ECDC. Avian influenza overview September - November 2025. EFSA Journal. Abstract
submitted by kickingbird at 1 days ago from EFSA Journal (via https://www.ecdc.europa.eu/en/publications-data/avian-influe)
The magnitude and geographical extent of these detections were unprecedented for this time of the year, particularly in wild birds. Large numbers of waterfowl were affected by the disease, and mass mortality ... Michelle Wille, etc.,al. [preprint]Ecology of low pathogenicity avian influenza virus H7 in wild birds in south-eastern Australia prior to emergence of high pathogenicity avian influenza H7 in poultry. https://doi.org/10.64898/2025.12.08.693062. Abstract
submitted by kickingbird at 1 days ago from https://doi.org/10.64898/2025.12.08.693062 (via https://www.biorxiv.org/content/10.64898/2025.12.08.693062v1)
Adding to the global burden of high pathogenicity avian influenza (HPAI) H5N1, an unprecedented five HPAI H7 outbreaks occurred globally in 2024. Of these, three occurred in southeast Australia, with the ... Sena Mursel, Brian D. Davison, Thomas McAndrew, Bi. Spatiotemporal Dynamics of Avian Influenza: Understanding Avian Influenza Transmission via Mallard Migration Data. Interdisciplinary Perspectives on Infectious Disea. Abstract
submitted by kickingbird at 1 days ago from Interdisciplinary Perspectives on Infectious Disea (via https://onlinelibrary.wiley.com/doi/10.1155/ipid/5555858)
Influenza, categorized as one of the emergent infectious diseases, presents a substantial public health concern due to its capacity to trigger extensive epidemics and global pandemics. Every recent pandemic ... Christopher A Gonelli, etc.,al. Low-level human memory T and B cells recognising avian influenza hemagglutinins are poorly responsive to existing seasonal influenza vaccines. Clinical & Translational Immunology. Abstract
submitted by kickingbird at 1 days ago from Clinical & Translational Immunology (via https://onlinelibrary.wiley.com/doi/10.1002/cti2.70067)
ObjectivesImmunisation remains the most cost-effective mechanism to combat influenza infection and is widely employed against seasonal influenza viruses. Zoonotic transmission of avian influenza A viruses ... Zhang, L., Shao, Y., Zou, X. et al. A primary oseltamivir-resistant mutation in influenza hemagglutinin and its implications for antiviral resistance surveillance. Nat Commun (2025). Abstract
submitted by kickingbird at 1 days ago from Nat Commun (2025) (via https://www.nature.com/articles/s41467-025-66307-5)
Oseltamivir, a neuraminidase (NA) inhibitor, is currently the most widely used antiviral drug for influenza worldwide. The emergence of primary oseltamivir-resistant mutations in NA protein of seasonally ... Tsafack, D., Monamele, C., Koro Koro, F. et al. Whole-genome analysis of influenza A(H1N1)pdm09 viruses in Cameroon (2019–2024) using nanopore sequencing. BMC Infect Dis (2025). Abstract
submitted by kickingbird at 2 days ago from BMC Infect Dis (2025) (via https://link.springer.com/article/10.1186/s12879-025-12284-5)
BackgroundSince 2019, Cameroon has reported a high number of seasonal influenza cases caused by the A(H1N1)pdm09 subtype, which remained the predominant global strain as of 2024.MethodsTo characterize ... Drake JM, Bahl J, Cacciatore MA, Ghadami A, Graede. Leveraging Systems-of-Systems Analysis to Strengthen Epidemic Intelligence for Preparedness and Response. Health Secur. 2025 Nov-Dec;23(6):400-410. Abstract
submitted by kickingbird at 2 days ago from Health Secur. 2025 Nov-Dec;23(6):400-410 (via https://www.liebertpub.com/doi/10.1177/23265094251396048)
The COVID-19 pandemic exposed significant gaps in the coordination and integration of efforts required to effectively manage large-scale infectious disease outbreaks. A successful response to such crises ... Pan Zhang, Raina MacIntyre. An overview of HPAI H5N1 clade 2.3.4.4b and its emerging threat in mainland Australia: Identified knowledge gaps. One Health, available online 10 December 2025. Abstract
submitted by kickingbird at 2 days ago from One Health, available online 10 December 2025 (via https://www.sciencedirect.com/science/article/pii/S235277142)
The highly pathogenic avian influenza (HPAI) H5N1 virus, particularly clade 2.3.4.4b, is currently causing a panzootic. The threat of its incursion into mainland Australia is escalating, especially following ... Pavithra Daulagala, Yonna W Y Leung, Leo L H Luk,. Anti-neuraminidase antibody responses in older adults after consecutive vaccinations with enhanced influenza vaccines: a randomized controlled trial. The Journal of Infectious Diseases, 2025;, jiaf616. Abstract
submitted by kickingbird at 2 days ago from The Journal of Infectious Diseases, 2025;, jiaf616 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
BackgroundAnti-neuraminidase antibodies have been identified as a correlate of protection for influenza virus infection. We evaluated the immunogenicity of enhanced influenza vaccines versus standard-dose ... Higerd-Rusli GP, Karan A, Hoffman SA, Morante IEA,. One confirmed and one potential human case of influenza A(H5N1) detected through an expanded subtyping protocol. ASM Case Rep 0:e00165-25. Abstract
submitted by kickingbird at 2 days ago from ASM Case Rep 0:e00165-25 (via https://journals.asm.org/doi/10.1128/asmcr.00165-25)
Current U.S. surveillance for highly pathogenic avian influenza A(H5N1) in humans prioritizes individuals with known animal exposures, potentially missing community-acquired infections. To address this ... Kar J, Hirohama M, Nakayama K, Lee S, Kawaguchi A. Microtubule detyrosination links inflammasome activation to apoptotic cell death in macrophages upon influenza A virus infection. J Virol. 2025 Dec 9:e0184725. Abstract
submitted by kickingbird at 2 days ago from J Virol. 2025 Dec 9:e0184725 (via https://journals.asm.org/doi/10.1128/jvi.01847-25)
The tubulin code, defined by diverse post-translational modifications of microtubules, fine-tunes microtubule dynamics, regulating downstream cellular signaling. Among these, detyrosination of α-tubulin ... Ganesh V, Iampietro J, Sridhar S, Goncalvez AP. Human Immune Response to Influenza Neuraminidase After Vaccination: A Systematic Review. Influenza Other Respir Viruses. 2025 Dec;19(12):e7. Abstract
submitted by kickingbird at 2 days ago from Influenza Other Respir Viruses. 2025 Dec;19(12):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70192)
Background: Licensed influenza vaccines primarily target hemagglutinin (HA)-related immunity, but neuraminidase (NA)-based immunity is gaining attention as an independent correlate of protection. Inactivated ... Ivan Tomic, etc.,al. [preprint]Innate antiviral readiness drives the expansion of protective T stem cell memory against influenza. https://doi.org/10.64898/2025.12.06.692757. Abstract
submitted by kickingbird at 2 days ago from https://doi.org/10.64898/2025.12.06.692757 (via https://www.biorxiv.org/content/10.64898/2025.12.06.692757v1)
The development of T-cell-based influenza vaccines relies on eliciting broad CD8+ T-cell immunity, wherein T stem cell-like memory (TSCM) cells serve as the ultimate long-lived reservoir for immune memory, ... Wang X, Mao H, Kong L, Xu Z, Liu S, Ren J, Sun Z,. Clinical and epidemiological characteristics of four human cases of avian influenza virus infection in Zhejiang Province, China, 2021-2024. Infect Dis. 2025 Dec 8:1-11. Abstract
submitted by kickingbird at 3 days ago from Infect Dis. 2025 Dec 8:1-11 (via https://www.tandfonline.com/doi/full/10.1080/23744235.2025.2)
Background: Avian influenza A viruses (AIVs) remain a global public health concern. Sporadic human infections continue to be reported, particularly in areas with frequent human-poultry contact. We report ... Matteo Chiara, etc.,al. [preprint]Distinctive viral genome signatures are linked to repeated mammalian spillovers of H5N1 in North America. https://doi.org/10.64898/2025.12.09.693147. Abstract
submitted by kickingbird at 3 days ago from https://doi.org/10.64898/2025.12.09.693147 (via https://www.biorxiv.org/content/10.64898/2025.12.09.693147v1)
Highly pathogenic avian influenza H5N1 rarely infects mammals. In 2024-2025, however, genotypes B3.13 and D1.1 caused two independent spillovers into U.S. dairy cattle. By analysing 26,930 complete H5N1 ... Wang X, Liu X, Wang S, Wang Q, Wang J, Wang M, Yao. Identification of the Key Amino Acid Mutations in the PB2 and PA Proteins of Classical Swine H1N1 Influenza A Virus in Mammalian Adaptation. Emerg Microbes Infect. 2025 Dec 9:2602310. Abstract
submitted by kickingbird at 3 days ago from Emerg Microbes Infect. 2025 Dec 9:2602310 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
The classical swine (CS) H1N1 influenza virus firstly isolated in 1930 is highly homologous to the 1918 Spanish influenza virus. CS H1N1 virus crossed the interspecies barrier to infect humans has become ... 9534 items, 20/Page, Page[1/477][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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