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2026-10-7 12:18:18
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Elizabeth Billington, etc.,al. [preprint]The mammalian-adaptive PB2-E627K substitution preserves viral fitness of clade 2.3.4.4b H5N1 HPAIV in birds. https://doi.org/10.64898/2026.10.06.757006.  Abstract  
submitted by kickingbird at 8 minute(s) ago from https://doi.org/10.64898/2026.10.06.757006 (via https://www.biorxiv.org/content/10.64898/2026.10.06.757006v1)
Since emerging in 2020, clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus (HPAIV) has disseminated globally, causing substantial infection and mortality in wild birds and poultry. Additionally, ...

Ruth N, Shakya M, Lewis CD, Erickson CE, Dolinski. Mallard super-shedders of avian influenza exhibit distinct cloacal microbial abundance profiles. Microbiol Spectr. 2026 Oct 6:e0208926.  Abstract  
submitted by kickingbird at 4 hours ago from Microbiol Spectr. 2026 Oct 6:e0208926 (via https://journals.asm.org/doi/10.1128/spectrum.02089-26)
In many infectious disease systems, a small fraction of hosts accounts for a disproportionate share of transmission, but the biological basis of this heterogeneity remains poorly resolved. In avian influenza, ...

Del Rosario JMM, van Diemen PM, Frost SDW, Vishwan. A digitally immune-optimized influenza vaccine broadly neutralizes swine and human H1N1 influenza viruses and protects from heterologous challenge. J Virol. 2026 Oct 6:e0107326.  Abstract  
submitted by kickingbird at 4 hours ago from J Virol. 2026 Oct 6:e0107326 (via https://journals.asm.org/doi/10.1128/jvi.01073-26)
Influenza A virus (IAV) zoonotic transmission and continuous evolution in multiple host species heighten the risk of emerging novel strains at the human-animal interface. Digitally immune-optimized hemagglutinin ...

Zhang, X., Deng, X., Liang, Y. et al. Associations between vaccine misinformation and influenza vaccine uptake: a population-based interrupted time-series study in China. npj Digit. Public Health 1, 40 (2026).  Abstract  
submitted by kickingbird at 5 hours ago from npj Digit. Public Health 1, 40 (2026) (via https://link.springer.com/article/10.1038/s44482-026-00047-1)
Vaccine misinformation is linked to vaccine hesitancy, yet real-world evidence of its association with vaccine uptake remains limited. Most existing studies rely on self-reported intentions or experimental ...

Nooruzzaman M, Buchholz DW, Rani R, de Oliveira PS. Infection and transmission dynamics of bovine and human influenza A H5N1 viruses in mouse and hamster models. Pathogenesis and Host Response.  Abstract  
submitted by kickingbird at 5 hours ago from Pathogenesis and Host Response (via https://journals.asm.org/doi/10.1128/jvi.01044-26)
Here we investigated the pathogenesis and contact transmission of bovine- and human-derived highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b genotype B3.13 viruses in mammalian models. Using ...

Guo T, Ming B, Liang Y, Lu F, Ma W, Zhang J. Role-specific household contact patterns in urban and rural China: Implications for influenza household transmission. Infect Dis Model. 2026 Sep 2;12(1):154-169.  Abstract  
submitted by kickingbird at 17 hours ago from Infect Dis Model. 2026 Sep 2;12(1):154-169 (via https://www.sciencedirect.com/science/article/pii/S246804272)
Background: Household contact patterns significantly influence the household transmission dynamics of respiratory pathogens. Previous studies have shown ignoring the heterogeneity of household contact ...

Lin Z, Chen J, Su G, Wang H, Deng R, Tian S, Yang. Persistent influenza A RNA detection in a fatal pediatric case of influenza-associated encephalopathy. J Infect Public Health. 2026 Oct 1;19(11):103380.  Abstract  
submitted by kickingbird at 17 hours ago from J Infect Public Health. 2026 Oct 1;19(11):103380 (via https://www.sciencedirect.com/science/article/pii/S187603412)
Influenza-associated encephalopathy (IAE) is a life-threatening complication of influenza. We report a case of a 9-year-old boy diagnosed with fulminant IAE. The patient received life-sustaining support, ...

Durand LO, Olsen SJ, Wendling NM, Uyeki TM, Mirabi. How can veterinary personnel recognize and protect themselves from domestic cats infected with highly pathogenic avian influenza A(H5N1) viruses?. J Am Vet Med Assoc. 2026 Oct 2:1-4.  Abstract  
submitted by kickingbird at 3 days ago from J Am Vet Med Assoc. 2026 Oct 2:1-4 (via https://avmajournals.avma.org/view/journals/javma/aop/javma.)
Highly pathogenic avian influenza A(H5N1) viruses circulate globally in wild birds, causing poultry outbreaks and spillover infections in mammals and sporadic human infections. Recent detections in domestic ...

Wang Y, Wang S, Cheng H, Meng Z, Zhai X, Lv R, Gua. A Thermosensitive Mucoadhesive Hydrogel for Nasal Influenza Vaccine Delivery Elicits Robust Systemic and Mucosal Immunity. Adv Healthc Mater. 2026 Oct 3:e71773.  Abstract  
submitted by kickingbird at 3 days ago from Adv Healthc Mater. 2026 Oct 3:e71773 (via https://advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.71)
Influenza virus invades the host through the respiratory mucosa, making local immunity at the infection site critical for blocking transmission. However, the nasal mucus-cilia clearance barrier severely ...

Kelsey M Sumner, etc.,al. [preprint]Comparative immunogenicity and relative vaccine efficacy of recombinant and cell culture-based influenza vaccines: Results from a randomized trial of adults in the United States, 2024-2025. https://doi.org/10.64898/2026.10.01.26364413.  Abstract  
submitted by kickingbird at 3 days ago from https://doi.org/10.64898/2026.10.01.26364413 (via https://www.medrxiv.org/content/10.64898/2026.10.01.26364413)
Background: Recombinant (RIV) and cell culture-based inactivated (ccIIV) influenza vaccines could improve seasonal influenza prevention; however, evidence is limited in how protection may differ among ...

Abhishek Bastiray, etc.,al. [preprint]Network analysis of correlated conformational dynamics across the evolution of influenza A virus NS1. https://doi.org/10.64898/2026.09.29.755463.  Abstract  
submitted by kickingbird at 3 days ago from https://doi.org/10.64898/2026.09.29.755463 (via https://www.biorxiv.org/content/10.64898/2026.09.29.755463v1)
Protein evolution requires sequence changes to alter molecular properties without disrupting the dynamic organization necessary for function. How residue-level networks of correlated motions accommodate ...

Lauren Stewart Stafford, etc.,al. [preprint]Intranasal adenovirus type 5 influenza vaccination enhances milk antibody responses and passive transfer to neonatal ferrets. https://doi.org/10.64898/2026.09.26.754702.  Abstract  
submitted by kickingbird at 3 days ago from https://doi.org/10.64898/2026.09.26.754702 (via https://www.biorxiv.org/content/10.64898/2026.09.26.754702v2)
Newborns and infants are particularly vulnerable to influenza, largely due to the immaturity of their immune systems. As such, maternal immunization is a valuable strategy to enhance influenza-neutralizing ...

Steinar Mannsverk, etc.,al. [preprint]Tuning nanoscale lipid clustering controls influenza viral binding. https://doi.org/10.64898/2026.09.28.755053.  Abstract  
submitted by kickingbird at 3 days ago from https://doi.org/10.64898/2026.09.28.755053 (via https://www.biorxiv.org/content/10.64898/2026.09.28.755053v1)
Influenza virus attaches to cells by binding to sialylated glycans. Subsequent endocytosis of the virus and endosomal maturation leads to a conformational change in the hemagglutinin coat protein that ...

Yang, X., Shi, J., Li, X. et al. Influenza A virus nonstructural protein 2 inhibits IFN-I signaling via competing with MAVS to bind to UBL7. Virol J (2026).  Abstract  
submitted by kickingbird at 3 days ago from Virol J (2026) (via https://link.springer.com/article/10.1186/s12985-026-03316-w)
Influenza A virus (IAV) utilizes multiple strategies to antagonize type I interferon (IFN-I)-mediated antiviral responses to enhance its propagation within the host. Nonstructural protein 2 (NS2) is a ...

Jim H, Butt E, Murray BS, Spence KL. Canadian News Media Coverage of Government-Mandated Depopulation Policies During Highly Pathogenic Avian Influenza Outbreaks-A Sentiment Analysis. Agriculture. 2026; 16(19):2130.  Abstract  
submitted by kickingbird at 3 days ago from Agriculture. 2026; 16(19):2130 (via https://www.mdpi.com/2077-0472/16/19/2130)
This study examines how Canadian news media portrayed government-mandated depopulation during Highly Pathogenic Avian Influenza (HPAI) outbreaks and identified patterns in reporting tone and language. ...

Fenner GdO, Thomazelli LM, Dorlass EG, Eisen AKA,. Genomic Characterization of a Reassortant A/H1N8 Avian Influenza Virus in South American Migratory Shorebirds. Pathogens. 2026; 15(10):1039.  Abstract  
submitted by kickingbird at 3 days ago from Pathogens. 2026; 15(10):1039 (via https://www.mdpi.com/2076-0817/15/10/1039)
Avian influenza viruses (AIVs) circulate widely among migratory birds, where frequent reassortment drives the emergence of novel genomic constellations. However, the evolutionary pathways underlying these ...

Klivleyeva N, Glebova T, Baimukhametova A, Karamen. Study of Molecular Genetic Characteristics of Influenza A(H1N1) Viruses Identified During Monitoring in Kazakhstan (2023-2026). Viruses. 2026; 18(10):1087.  Abstract  
submitted by kickingbird at 3 days ago from Viruses. 2026; 18(10):1087 (via https://www.mdpi.com/1999-4915/18/10/1087)
Background/Objectives: Seasonal influenza threatens global public health through rapid mutations. This study evaluated the prevalence and molecular-genetic characteristics of seasonal influenza viruses ...

Montes JL, Juárez X, Lloveras S, Cordero AP, Saenz. Seasonal Influenza Vaccination Policies for Poultry Workers in 33 Pan American Health Organization Member States in 2026: A Review. Vaccines. 2026; 14(10):871.  Abstract  
submitted by kickingbird at 3 days ago from Vaccines. 2026; 14(10):871 (via https://www.mdpi.com/2076-393X/14/10/871)
Background/Objective: Since 2004, seasonal influenza vaccination has been technically recommended for poultry workers as a public health measure to reduce the risk of co-infection with human and avian ...

Wang G, Cao H, Yan Y, Wang L, Sun Y, Feng D. Real-World Effectiveness of Influenza Vaccination Against Medically Attended Influenza and Severe Outcomes Among Older Adults in Yichang, China: A Multi-Season Population-Based Cohort Study. Vaccines. 2026; 14(10):858.  Abstract  
submitted by kickingbird at 3 days ago from Vaccines. 2026; 14(10):858 (via https://www.mdpi.com/2076-393X/14/10/858)
Background/Objectives: Real-world evidence on influenza vaccine effectiveness (VE) against severe outcomes among older adults in China remains limited. We evaluated influenza vaccination against medically ...

Lisgara M, Sofia M, Liontos C, Ntarampa N, Skampar. Swine Influenza A Virus Seropositivity in Greek Pig Farms: Sampling-Occasion and Age-Group Patterns, 2020-2022. Zoonotic Diseases. 2026; 6(4):42.  Abstract  
submitted by kickingbird at 3 days ago from Zoonotic Diseases. 2026; 6(4):42 (via https://www.mdpi.com/2813-0227/6/4/42)
Swine influenza A virus (swIAV) is a respiratory pathogen of pigs with zoonotic potential. This investigation evaluated overall and subtype-specific seropositivity in 2889 sera with available haemagglutination ...

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