Zhuang, Y., Chen, L., Qin, C. et al. A nanobody-based proteolysis-targeting chimera offers broad-spectrum protection against diverse influenza virus infections. Sig Transduct Target Ther 11, 182 (2026). Abstract
submitted by kickingbird at 24 hours ago from Sig Transduct Target Ther 11, 182 (2026) (via https://link.springer.com/article/10.1038/s41392-026-02666-9)
Influenza A viruses continue to pose a major threat to global public health. In addition to H1N1 and H3N2 subtypes causing seasonal epidemics that result in an estimated 3–5 million severe cases and 290,000–650,000 ... Sun, X., Lisboa, C., Carney, P.J. et al. Hemagglutinin E190D substitution in clade 2.3.4.4b A(H5N1) influenza virus reduces receptor binding and viral fitness. npj Viruses (2026). Abstract
submitted by kickingbird at 24 hours ago from npj Viruses (2026) (via https://www.nature.com/articles/s44298-026-00197-2)
The detection of a clade 2.3.4.4b influenza A(H5N1) virus bearing an HA-E190D substitution in an infected human raises concern about mammalian adaptation. We evaluated the impact of the naturally occurring ... Oremush R, Aubry P, Parmley EJ, Poljak Z, Greer A. Determining the Environmental and Ecological Factors Associated With Poultry Farm Spillover of Highly Pathogenic Avian Influenza (H5N1) in British Columbia, Canada. Zoonoses Public Health. 2026 May 15. Abstract
submitted by kickingbird at 1 days ago from Zoonoses Public Health. 2026 May 15 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.70065)
Introduction: Highly pathogenic avian influenza (HPAI) H5N1, clade 2.3.4.4b is a global threat causing widespread outbreaks on poultry farms and high mortality among wild bird populations in Canada. Wild ... Phung Nguyen The Nguyen, Nguyen Thanh Hung, Ngo Ng. Central Nervous System Involvement by Novel Clade 2.3.2.1e H5N1 Avian Influenza Virus in a Paediatric Patient. Open Forum Infectious Diseases, 2026;, ofag283. Abstract
submitted by kickingbird at 2 days ago from Open Forum Infectious Diseases, 2026;, ofag283 (via https://academic.oup.com/ofid/advance-article/doi/10.1093/of)
Novel clade 2.3.2.1e A(H5N1) virus was detected in cerebrospinal fluid but not in respiratory, rectal-swab and blood samples of an eight-year-old boy presenting with meningoencephalitis without respiratory ... Rolfes MA, Bauck L, Lipton BA, et al. Knowledge, Attitudes, and Practices Regarding Avian Influenza Among Owners of Backyard Flocks - United States, July-December 2025. Morb Mortal Wkly Rep 2026;75:234-239. Abstract
submitted by kickingbird at 2 days ago from Morb Mortal Wkly Rep 2026;75:234-239 (via https://www.cdc.gov/mmwr/volumes/75/wr/mm7518a2.htm)
Many U.S. households keep backyard bird flocks for their personal food supply or as garden partners. Backyard flocks in the United States have occasionally been infected with avian influenza A viruses, ... Mengyang Zhang, etc.,al. Sunlight Inactivation of Influenza A Virus and Bacteriophages on an Acrylic Surface. Environ. Sci. Technol. 2026, 60, 16, 11960–11970. Abstract
submitted by kickingbird at 2 days ago from Environ. Sci. Technol. 2026, 60, 16, 11960–11970 (via https://pubs.acs.org/doi/10.1021/acs.est.5c13082)
Seasonal epidemics and pandemics of influenza cause a large public health burden, with transmission occurring via contact with contaminated fomites. Sunlight has been shown to inactivate viruses in water, ... Andrey Coatrini-Soares, etc.,al. Microfluidic Electronic Tongue Made with Nanostructured Films of Proteins from Renewable Sources to Detect H5N1 Antibodies from Avian Influenza Virus. ACS Appl. Nano Mater. 2026, 9, 15, 6581–6590. Abstract
submitted by kickingbird at 2 days ago from ACS Appl. Nano Mater. 2026, 9, 15, 6581–6590 (via https://pubs.acs.org/doi/10.1021/acsanm.6c00138)
Avian influenza viruses, particularly the H5N1 subtype, represent a major global threat due to their high transmissibility and mortality rates. Rapid, low-cost, and reliable detection is essential for ... Kota Matsumoto, etc.,al. Viral Membrane-Targeting Amphipathic Helical Peptide Ligands for Colorimetric Sandwich Assays of Influenza A Virus Particles. ACS Sens. 2026. Abstract
submitted by kickingbird at 2 days ago from ACS Sens. 2026 (via https://pubs.acs.org/doi/10.1021/acssensors.6c00241)
Viral membrane-binding amphipathic helical (AH) peptides were explored as detection ligands in the sandwich-type colorimetric assay for selective detection of target influenza A virus (IAV) particles, ... Jun Jiao, etc.,al. [preprint]G4 Eurasian avian-like H1N1 swine influenza viruses exhibit enhanced pathogenicity potential in mice and pigs. https://doi.org/10.64898/2026.05.12.724537. Abstract
submitted by kickingbird at 3 days ago from https://doi.org/10.64898/2026.05.12.724537 (via https://www.biorxiv.org/content/10.64898/2026.05.12.724537v1)
Currently circulating swine influenza viruses (SIVs) mainly include H1N1, H1N2, and H3N2 subtypes. In this study, two G4 genotype Eurasian avian-like (EA) H1N1 SIVs were isolated from 556 samples collected ... Alejandra Garcia-Glaessner, etc.,al. [preprint]Outbreak of H9N2 avian influenza viruses in lesser rhea in Peru, June-July 2025. https://doi.org/10.64898/2026.05.08.723762. Abstract
submitted by kickingbird at 3 days ago from https://doi.org/10.64898/2026.05.08.723762 (via https://www.biorxiv.org/content/10.64898/2026.05.08.723762v1)
Avian influenza viruses (AIVs) are endemic in the Americas and responsible for outbreaks in both domestic and wild birds that occasionally spill over into humans. We report the first known outbreak of ... Nathaniel Jackson, etc.,al. [preprint]A single PA-X mutation in bovine-origin H5N1 influenza virus reduces pathogenicity in mice. https://doi.org/10.64898/2026.05.09.724031. Abstract
submitted by kickingbird at 3 days ago from https://doi.org/10.64898/2026.05.09.724031 (via https://www.biorxiv.org/content/10.64898/2026.05.09.724031v1)
Dairy cows have emerged as a reservoir for human infection with highly pathogenic avian influenza (HPAI) H5N1. At the bovine–human interface, H5N1 strains may acquire adaptive mutations that influence ... Ort, J.T., Sobel Leonard, A., Li, S.H. et al. Cross-reactive human antibody responses to H5N1 influenza virus neuraminidase are shaped by immune history. Nat Commun (2026). Abstract
submitted by kickingbird at 3 days ago from Nat Commun (2026) (via https://link.springer.com/article/10.1038/s41467-026-72941-4)
H5N1 highly pathogenic avian influenza viruses have spread globally and pose a pandemic risk. Prior studies suggest that early life exposures to group 1 influenza viruses (H1N1 and H2N2) prime antibodies ... Yang H, Zhang Y, Wang X, Chen T, Jia Y, Dou H, Jia. Epidemiological and Genomic Characterization of H5 Subtype Avian Influenza Viruses in Jining City, 2024–2025. Pathogens. 2026; 15(5):521. Abstract
submitted by kickingbird at 3 days ago from Pathogens. 2026; 15(5):521 (via https://www.mdpi.com/2076-0817/15/5/521)
Objective: The aim of this study was to characterize the epidemiological features and whole-genome characteristics of H5 subtype avian influenza viruses circulating in Jining City during 2024–2025, and ... Zhou L, Li X, Chen J, Liu Y, Zhang Y, Gong X, Meng. Screening of Low-Tumorigenic MDCK Cells for Potential Influenza Vaccine Substrates and Transcriptomic Analyses. International Journal of Molecular Sciences. 2026. Abstract
submitted by kickingbird at 3 days ago from International Journal of Molecular Sciences. 2026 (via https://www.mdpi.com/1422-0067/27/9/3875)
Since MDCK cells are inherently tumorigenic, their safety in vaccine production has long been a concern; thus, establishing a screening method for low-tumorigenic cells is of great significance for influenza ... Huang, J., Ma, K., Ding, S., Wang, Y., Xiong, J.,. A CRISPR activation screen identifies CH25H as a restriction factor against influenza viruses by targeting accessible cholesterol. Emerging Microbes & Infections. Abstract
submitted by kickingbird at 3 days ago from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Influenza A viruses (IAVs) cause severe outbreaks with high mortality in birds and humans. A deeper understanding of cell-intrinsic defense mechanisms against influenza viruses is therefore crucial for ... Steiner J, Mwanga M, et al. Concurrent Detection of Swine-Origin Influenza A(H1N1) Virus in Pigs and Farmer, Switzerland. Emerg Infect Dis. 2026 Jun. Abstract
submitted by kickingbird at 3 days ago from Emerg Infect Dis. 2026 Jun (via https://wwwnc.cdc.gov/eid/article/32/6/25-1487_article)
We report zoonotic transmission of Eurasian avian-like swine influenza A(H1N1) virus from pigs to a farmer. The pigs and farmer experienced influenza-like illness. Whole-genome sequencing revealed >99.9% ... Eszter Kovács, etc.,al. H5N1 2.3.4.4b HA E190D and Q226H mutations, picked up as minority variants in a patient, result in an inability to bind sialic acid. Virology. Abstract
submitted by kickingbird at 4 days ago from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
A human infection with clade 2.3.4.4b H5N1 influenza A virus in Canada revealed minority variants E190D and Q226H in the hemagglutinin (HA) receptor-binding site (RBS). Because mutations at positions 190 ... Zhiyuan Liu, etc.,al. Gga-miR-449c suppresses H9N2 influenza virus replication via targeting the viral genome and suppressor of cytokine signaling 3. International Journal of Biological Macromolecules. Abstract
submitted by kickingbird at 4 days ago from International Journal of Biological Macromolecules (via https://www.sciencedirect.com/science/article/abs/pii/S01418)
Avian influenza virus is a globally prevalent pathogen in poultry populations, causing severe economic losses to the poultry industry worldwide. In the present study, we demonstrate that miR-449c generates ... Chen X, Zheng X, Zhang L, Cai X, Hong X, Hou S, Ma. Long noncoding RNA#61 synergizes with viral PA-X to augment pyroptosis and attenuate the virulence of highly pathogenic H5N1 influenza virus in mice. J Virol 0:e02214-25. Abstract
submitted by kickingbird at 4 days ago from J Virol 0:e02214-25 (via https://journals.asm.org/doi/10.1128/jvi.02214-25)
Long non-coding RNAs (LncRNAs) play pivotal regulatory roles in various biological processes, notably in immune regulation and viral infection. We previously identified the broad anti-influenza activity ... Chen Bin, etc.,al. Analysis of Avian Influenza Virus Contamination in Poultry-Related Environments in Shaanxi Province from 2020 to 2024. Chinese Journal of Epidemiology 2026, 47(03):515. Abstract
submitted by kickingbird at 4 days ago from Chinese Journal of Epidemiology 2026, 47(03):515 (via http://chinaepi.icdc.cn/zhlxbx/ch/reader/view_abstract.aspx?)
Objective: To analyze the avian influenza virus (AIV) contamination in poultry-related environments in Shaanxi Province and provide a reference for strengthening regional avian influenza prevention and ... 10124 items, 20/Page, Page[1/507][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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