Ran W, Sch?n J, Ciminski K, Kraft J, Kessler S, Eu. Generation of an Attenuated Chimeric Bat Influenza A Virus Live-Vaccine Prototype. Microbiol Spectr. 2022 Nov 29:e0142422. Abstract
submitted by kickingbird at 2 days ago from Microbiol Spectr. 2022 Nov 29:e0142422 (via https://journals.asm.org/doi/10.1128/spectrum.01424-22)
Recurring epizootic influenza A virus (IAV) infections in domestic livestock such as swine and poultry are associated with a substantial economic burden and pose a constant threat to human health. Therefore, ...
Xu X, Chen Q, Tan M, Liu J, Li X, Yang L, Shu Y, W. Epidemiology, evolution, and biological characteristics of H6 avian influenza viruses in China. Emerg Microbes Infect. 2022 Nov 28:1-39. Abstract
submitted by kickingbird at 4 days ago from Emerg Microbes Infect. 2022 Nov 28:1-39 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2022.2)
H6 avian influenza virus (AIV) is one of the most prevalent AIV subtypes in birds globally. To investigate the current situation and characteristics of H6 AIVs circulating in China, we analysed the epidemiology, ...
Zhang C, Cui H, Zhang C, Zhao K, Kong Y, Chen L, D. Pathogenicity and Transmissibility of Clade 22.214.171.124h H5N6 Avian Influenza Viruses in Mammals. Animals (Basel). 2022 Nov 9;12(22):3079. Abstract
submitted by kickingbird at 4 days ago from Animals (Basel). 2022 Nov 9;12(22):3079 (via https://www.mdpi.com/2076-2615/12/22/3079)
Avian influenza viruses (AIVs) have the potential for cross-species transmission and pandemics. In recent years, clade 126.96.36.199 H5N6 AIVs are prevalent in domestic poultry, posing a threat to the domestic ...
Lei H, Yang M, Dong Z, Hu K, Chen T, Yang L, Zhang. Indoor relative humidity shapes influenza seasonality in temperate and subtropical climates in China. Int J Infect Dis. 2022 Nov 22:S1201-9712(22)00613-. Abstract
submitted by kickingbird at 4 days ago from Int J Infect Dis. 2022 Nov 22:S1201-9712(22)00613- (via https://www.ijidonline.com/article/S1201-9712(22)00613-0/ful)
Objective: The aim of this study was to explore whether indoor or outdoor relative humidity (RH) modulates the influenza epidemics transmission in temperate and subtropical climates.Methods: In this study, ...
Mashaal D, Mahmoud SH, Müller C, Abo Shama NM, Kam. Differential Impact of Specific Amino Acid Residues on the Characteristics of Avian Influenza Viruses in Mammalian Systems. Pathogens. 2022 Nov 19;11(11):1385. Abstract
submitted by kickingbird at 7 days ago from Pathogens. 2022 Nov 19;11(11):1385 (via https://www.mdpi.com/2076-0817/11/11/1385)
Avian influenza virus (AIV) H9N2 was declared to be endemic in birds of the Middle East, in particular in Egypt, with multiple cases of human infections. Despite concerns about the pandemic threat posed ...
Marchenko V, Mukhametdinova D, Amosova I, Lioznov. Influenza A(H1N1)pdm09 Virus Alters Expression of Endothelial Factors in Pulmonary Vascular Endothelium in Rats. Viruses. 2022 Nov 14;14(11):2518. Abstract
submitted by kickingbird at 7 days ago from Viruses. 2022 Nov 14;14(11):2518 (via https://www.mdpi.com/1999-4915/14/11/2518)
Influenza virus infection may cause endothelial activation and dysfunction. However, it is still not known to what extent the influenza virus can dysregulate the expression of various endothelial proteins. ...
Wang Y, Li X, Xu Q, Niu X, Zhang S, Qu X, Chu H, C. Characterization of Neutralizing Monoclonal Antibodies and Identification of a Novel Conserved C-Terminal Linear Epitope on the Hemagglutinin Protein of the H9N2 Avian Influenza Virus. Viruses. 2022 Nov 15;14(11):2530. Abstract
submitted by kickingbird at 7 days ago from Viruses. 2022 Nov 15;14(11):2530 (via https://www.mdpi.com/1999-4915/14/11/2530)
The H9N2 avian influenza virus (AIV) remains a serious threat to the global poultry industry and public health. The hemagglutinin (HA) protein is an essential protective antigen of AIVs and a major target ...
Yang J, Guo X, Zhang T, Wang Q, Zhang X, Yang J, L. The Impact of Urbanization and Human Mobility on Seasonal Influenza in Northern China. Viruses. 2022 Nov 19;14(11):2563. Abstract
submitted by kickingbird at 7 days ago from Viruses. 2022 Nov 19;14(11):2563 (via https://www.mdpi.com/1999-4915/14/11/2563)
The intensity of influenza epidemics varies significantly from year to year among regions with similar climatic conditions and populations. However, the underlying mechanisms of the temporal and spatial ...
Liu T, Huang Y, Xie S, Xu L, Chen J, Qi W, Liao M,. A Characterization and an Evolutionary and a Pathogenicity Analysis of Reassortment H3N2 Avian Influenza Virus in South China in 2019-2020. Viruses. 2022 Nov 21;14(11):2574. Abstract
submitted by kickingbird at 7 days ago from Viruses. 2022 Nov 21;14(11):2574 (via https://www.mdpi.com/1999-4915/14/11/2574)
Seasonal H3N2 influenza virus has always been a potential threat to public health. The reassortment of the human and avian H3N2 influenza viruses has resulted in major influenza outbreaks, which have seriously ...
Arevalo CP, Bolton MJ, Le Sage V, Ye N, Furey C, M. A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes. Science. 2022 Nov 25;378(6622):899-904. Abstract
submitted by kickingbird at 7 days ago from Science. 2022 Nov 25;378(6622):899-904 (via https://www.science.org/doi/10.1126/science.abm0271)
Seasonal influenza vaccines offer little protection against pandemic influenza virus strains. It is difficult to create effective prepandemic vaccines because it is uncertain which influenza virus subtype ...
Liu T, Peng Y, Wu J, Lu S, He Y, Li X, Sun L, Song. Surveillance of avian influenza viruses in live bird markets of Shandong province from 2013 to 2019. Front Microbiol. 2022 Nov 3;13:1030545. Abstract
submitted by kickingbird at 10 days ago from Front Microbiol. 2022 Nov 3;13:1030545 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.1030)
Avian influenza viruses (AIVs) seriously affect the poultry industry and pose a great threat to humans. Timely surveillance of AIVs is the basis for preparedness of the virus. This study reported the long-term ...
Niqueux é, Flodrops M, Allée C, Lebras MO, Pierre. Evaluation of three hemagglutinin-based vaccines for the experimental control of a panzootic clade 188.8.131.52b A(H5N8) high pathogenicity avian influenza virus in mule ducks. Vaccine. 2022 Nov 18:S0264-410X(22)01398-6. Abstract
submitted by kickingbird at 10 days ago from Vaccine. 2022 Nov 18:S0264-410X(22)01398-6 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
In France during winter 2016-2017, 487 outbreaks of clade 184.108.40.206b H5N8 subtype high pathogenicity (HP) avian influenza A virus (AIV) infections were detected in poultry and captive birds. During this ...
Horwood PF, Horm SV, Yann S, Tok S, Chan M, Suttie. Aerosol exposure of live bird market workers to viable influenza A/H5N1 and A/H9N2 viruses, Cambodia. Zoonoses Public Health. 2022 Nov 21. Abstract
submitted by kickingbird at 10 days ago from Zoonoses Public Health. 2022 Nov 21 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.13009)
Live bird markets (LBMs) have been identified as key factors in the spread, persistence and evolution of avian influenza viruses (AIVs). In addition, these settings have been associated with human infections ...
Lai KK, Munro JB, Shi G, Majdoul S, Compton AA, Re. Restriction of Influenza A Virus by SERINC5. mBio. 2022 Nov 21:e0292322. Abstract
submitted by kickingbird at 10 days ago from mBio. 2022 Nov 21:e0292322 (via https://journals.asm.org/doi/10.1128/mbio.02923-22)
Serine incorporator 5 (Ser5), a transmembrane protein, has recently been identified as a host antiviral factor against human immunodeficiency virus (HIV)-1 and gammaretroviruses like murine leukemia viruses ...
Dong K, Gong H, Zhong G, Deng X, Tian Y, Wang M, Y. Estimating mortality associated with seasonal influenza among adults aged 65 years and above in China from 2011 to 2016: A systematic review and model analysis. Influenza Other Respir Viruses. 2022 Nov 17. Abstract
submitted by kickingbird at 14 days ago from Influenza Other Respir Viruses. 2022 Nov 17 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13067)
Background: Estimation of influenza disease burden is crucial for optimizing intervention strategies against seasonal influenza. This study aimed to estimate influenza-associated excess respiratory and ...
Liang Y, Hjulsager CK, Seekings AH, Warren CJ, Lea. Pathogenesis and infection dynamics of high pathogenicity avian influenza virus (HPAIV) H5N6 (clade 220.127.116.11b) in pheasants and onward transmission to chickens. Virology. 2022 Oct 29;577:138-148. Abstract
submitted by kickingbird at 15 days ago from Virology. 2022 Oct 29;577:138-148 (via https://www.sciencedirect.com/science/article/pii/S004268222)
High pathogenicity avian influenza viruses clade 18.104.22.168 H5 have spread among wild birds worldwide during recent years causing annual die-offs among wild birds and outbreaks in poultry in multiple European ...
Zhou L, Yang H, Pan W, Xu J, Feng Y, Zhang W, Shao. Association between meteorological factors and the epidemics of influenza (sub)types in a subtropical basin of Southwest China. Epidemics. 2022 Nov 9;41:100650. Abstract
submitted by kickingbird at Nov, 16, 2022 from Epidemics. 2022 Nov 9;41:100650 (via https://www.sciencedirect.com/science/article/pii/S175543652)
Background: The effects of climatic conditions on the prevalence of individual influenza (sub)types are not well understood in the subtropics. This study aims to evaluate the associations between meteorological ...
Miller ML, Brown DM, Wysocki TA. Modeling an Immune Response to Influenza A Virus Infection in Alveolar Epithelial Cells. Biotechnol Bioeng. 2022 Nov 15. Abstract
submitted by kickingbird at Nov, 16, 2022 from Biotechnol Bioeng. 2022 Nov 15 (via https://onlinelibrary.wiley.com/doi/10.1002/bit.28284)
Influenza A viruses (IAV) have been the cause of several influenza pandemics in history and are a significant threat for the next global pandemic. Hospitalized influenza patients often have excess interferon ...
Human infections with H7N9 avian influenza A virus. H7N9 avian influenza virus infection in men is associated with testosterone depletion. Nat Commun. 2022 Nov 14;13(1):6936. Abstract
submitted by kickingbird at Nov, 16, 2022 from Nat Commun. 2022 Nov 14;13(1):6936 (via https://www.nature.com/articles/s41467-022-34500-5)
Human infections with H7N9 avian influenza A virus that emerged in East China in 2013 and caused high morbidity rates were more frequently detected in men than in women over the last five epidemic waves. ...
Ahmed BM, Bayoumi MM, Farrag MA, Elgamal MA, Daly. Emergence of equine influenza virus H3Nx Florida clade 2 in Arabian racehorses in Egypt. Virol J. 2022 Nov 12;19(1):185. Abstract
submitted by kickingbird at Nov, 14, 2022 from Virol J. 2022 Nov 12;19(1):185 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Equine influenza is an important cause of respiratory disease in equids. The causative virus; EIV, is highly variable and can evolve by accumulation of mutations, particularly in the haemagglutinin ...
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