Good MR, Suja D, Guthmiller JJ. The sweet side of H5N1 influenza virus infection. PLoS Pathog 21(1): e1012847. Abstract
submitted by kickingbird at Jan, 24, 2025 from PLoS Pathog 21(1): e1012847 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
H5Nx viruses remain a threat to human health. Over the past few years, the H5Nx clade 2.3.4.4b has rapidly spread to 6 continents, leading to massive avian and mammalian host deaths. In late March 2024, ... Zhang M, Zeng Z, Chen X, Wang G, Cai X, Hu Z, Gu M. Phosphorylation of PA at serine 225 enhances viral fitness of the highly pathogenic H5N1 avian influenza virus in mice. Vet Microbiol. 2025 Jan 20;302:110400. Abstract
submitted by kickingbird at Jan, 24, 2025 from Vet Microbiol. 2025 Jan 20;302:110400 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Currently, there is increasing spillover of highly pathogenic H5N1 avian influenza virus (AIV) to mammals, raising a concern of pandemic threat about this virus. Although the function of PA protein of ... Song H, Hao T, Han P, Wang H, Zhang X, Li X, Wang. Receptor binding, structure, and tissue tropism of cattle-infecting H5N1 avian influenza virus hemagglutinin. Cell. 2025 Jan 22:S0092-8674(25)00048-0. Abstract
submitted by kickingbird at Jan, 24, 2025 from Cell. 2025 Jan 22:S0092-8674(25)00048-0 (via https://www.cell.com/cell/abstract/S0092-8674(25)00048-0)
The ongoing circulation of highly pathogenic avian influenza (HPAI) A (H5N1) viruses, particularly clade 2.3.4.4b strains, poses a significant threat to animal and public health. Recent outbreaks in cattle ... Sun R, Feng X, Huang J, Zheng F, Xie R, Zhang C, Z. Characterization of novel highly pathogenic avian influenza A(H5N6) clade 2.3.4.4b virus in wild birds, East China, 2024. Virol Sin. 2025 Jan 21:S1995-820X(25)00002-1. Abstract
submitted by kickingbird at Jan, 24, 2025 from Virol Sin. 2025 Jan 21:S1995-820X(25)00002-1 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Highlights?We reported a novel H5N6 HPAIV belonging to clade 2.3.4.4b in wild birds in eastern China.?The novel H5N6 HPAIV most likely descended from clade 2.3.4.4b H5N1 virus in Japan.?The novel H5N6 ... Yang Z, Ren ZD, Wang J, Dong W. Based on the MaxEnt model the analysis of influencing factors and simulation of potential risk areas of human infection with avian influenza A (H7N9) in China. Front Cell Infect Microbiol. 2025 Jan 3;14:1496991. Abstract
submitted by kickingbird at Jan, 21, 2025 from Front Cell Infect Microbiol. 2025 Jan 3;14:1496991 (via https://www.frontiersin.org/journals/cellular-and-infection-)
Exposure to infected animals and their contaminated environments may be the primary cause of human infection with the H7N9 avian influenza virus. However, the transmission characteristics and specific ... WPRO. WPRO/WHO: Avian Influenza Weekly Update, 17 January 2025. WHO. Abstract
submitted by kickingbird at Jan, 20, 2025 from WHO (via https://cdn.who.int/media/docs/default-source/wpro---documen)
From 10 to 16 January 2025, one new case of human infection with avian influenza A(H5N1) virus was reported to WHO in the Western Pacific Region. The case is a 28-year-old male from Kampong Cham Province, ... Ziegler E, Matthes KL, Middelkamp PW, Schuenemann. Retrospective modelling of the disease and mortality burden of the 1918-1920 influenza pandemic in Zurich, Switzerland. Epidemics. 2025 Jan 11;50:100813. Abstract
submitted by kickingbird at Jan, 19, 2025 from Epidemics. 2025 Jan 11;50:100813 (via https://www.sciencedirect.com/science/article/pii/S175543652)
Background: Our study aims to enhance future pandemic preparedness by integrating lessons from historical pandemics, focusing on the multidimensional analysis of past outbreaks. It addresses the gap in ... APHIS. Avian Influenza incidents and depopulation methods Feb 2022 to June 2024 in U.S.. USDA. Abstract
submitted by kickingbird at Jan, 19, 2025 from USDA (via https://www.aphis.usda.gov/sites/default/files/avian-influen)
APHIS posts online the records most frequently requested through the Freedom of Information of Act (FOIA), along with other agency documents of interest to the public. Mohammad Jawad Jahid,Jacqueline M Nolting. [preprint]From Birds to Bovine: A Review and Critical Analysis of the Outbreaks of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b in the United States. DOI:10.20944/preprints202501.0862.v1. Abstract
submitted by kickingbird at Jan, 19, 2025 from DOI:10.20944/preprints202501.0862.v1 (via https://www.preprints.org/manuscript/202501.0862/v1)
In late 2021, Eurasian-lineage highly pathogenic avian influenza (HPAI) A(H5N1) viruses from HA clade 2.3.4.4b were first detected in the United States, marking a significant milestone in their global ... Nemoto M, Kawanishi N, Kambayashi Y, Bannai H, Yam. Detection of equine influenza virus gene in the air around infected horses. Vet Microbiol. 2025 Jan 11;302:110388. Abstract
submitted by kickingbird at Jan, 19, 2025 from Vet Microbiol. 2025 Jan 11;302:110388 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Equine influenza virus (EIV) can be transmitted by inhalation of aerosolized droplets, direct contact, and contaminated fomites. However, to our knowledge, there are no reports of the recovery of EIV from ... Ray EL, Wang Y, Wolfinger RD, Reich NG. Flusion: Integrating multiple data sources for accurate influenza predictions. Epidemics. 2024 Dec 25;50:100810. Abstract
submitted by kickingbird at Jan, 18, 2025 from Epidemics. 2024 Dec 25;50:100810 (via https://www.sciencedirect.com/science/article/pii/S175543652)
Over the last ten years, the US Centers for Disease Control and Prevention (CDC) has organized an annual influenza forecasting challenge with the motivation that accurate probabilistic forecasts could ... Sullivan SG, Khvorov A, Carolan L, Dowson L, Hadip. Antibody responses against influenza A decline with successive years of annual influenza vaccination. NPJ Vaccines. 2025 Jan 17;10(1):11. Abstract
submitted by kickingbird at Jan, 18, 2025 from NPJ Vaccines. 2025 Jan 17;10(1):11 (via https://www.nature.com/articles/s41541-024-01057-x)
Influenza vaccine effectiveness and immunogenicity can be compromised with repeated vaccination. We assessed immunological markers in a cohort of healthcare workers (HCW) from six public hospitals around ... Gong HH, Worley MJ, Carver KA, Godin CJ, Deng JC. Deficient neutrophil responses early in influenza infection promote viral replication and pulmonary inflammation. PLoS Pathog. 2025 Jan 17;21(1):e1012449. Abstract
submitted by kickingbird at Jan, 18, 2025 from PLoS Pathog. 2025 Jan 17;21(1):e1012449 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Neutrophils play key protective roles in influenza infections, yet excessive neutrophilic inflammation is a hallmark of acute lung injury during severe infections. Phenotypic heterogeneity is increasingly ... Teo QW, Wang Y, Lv H, Oade MS, Mao KJ, Tan TJC, Hu. Probing the functional constraints of influenza A virus NEP by deep mutational scanning. Cell Rep. 2025 Jan 14;44(1):115196. Abstract
submitted by kickingbird at Jan, 18, 2025 from Cell Rep. 2025 Jan 14;44(1):115196 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(24)015)
The influenza A virus nuclear export protein (NEP) is a multifunctional protein that is essential for the viral life cycle and has very high sequence conservation. However, since the open reading frame ... Lambertucci, S.A., Santangeli, A. & Plaza, P.I. The threat of avian influenza H5N1 looms over global biodiversity. Nat. Rev. Biodivers. 1, 7–9 (2025). Abstract
submitted by kickingbird at Jan, 17, 2025 from Nat. Rev. Biodivers. 1, 7–9 (2025) (via https://link.springer.com/article/10.1038/s44358-024-00008-7)
The highly pathogenic avian influenza H5N1 is an emerging and unexpected threat to many wild animal species, which has implications for ecological processes, ecosystem services and conservation of threatened ... Yang, L., Fan, M. Reaction-advection-diffusion model of highly pathogenic avian influenza with behavior of migratory wild birds. J. Math. Biol. 90, 18 (2025). Abstract
submitted by kickingbird at Jan, 17, 2025 from J. Math. Biol. 90, 18 (2025) (via https://link.springer.com/article/10.1007/s00285-024-02181-x)
Wild birds are one of the main natural reservoirs for avian influenza viruses, and their migratory behavior significantly influences the transmission of avian influenza. To better describe the migratory ... Xue, Ruixue, Ma, Huiling, Jiang, Zixin, Xing, Linl. Diversity of the H9N2 Avian Influenza Virus in Shandong Province, China. Transboundary and Emerging Diseases, 2025, 1432483. Abstract
submitted by kickingbird at Jan, 17, 2025 from Transboundary and Emerging Diseases, 2025, 1432483 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/1432483)
H9N2 avian influenza virus (AIV) is one of the main pathogens causing respiratory disease in chicken; however, differentiating this virus from infectious bronchitis virus (IBV) and newcastle disease virus ... Duong MH, Phan TNU, Nguyen TH, Ho NHN, Nguyen TN,. Human Infection with Avian Influenza A(H9N2) Virus, Vietnam, April 2024. Emerg Infect Dis. Feb 2025. Abstract
submitted by kickingbird at Jan, 17, 2025 from Emerg Infect Dis. Feb 2025 (via https://wwwnc.cdc.gov/eid/article/31/2/24-1146_article)
In April 2024, Vietnam confirmed its first human case of influenza A(H9N2) in a 37-year-old man, marking a critical point in regional infectious disease monitoring and response. This case underscores the ... Zhang C, Hou J, Li Z, Shen Q, Bai H, Chen L, Shen. PROTAR Vaccine 2.0 generates influenza vaccines by degrading multiple viral proteins. Nat Chem Biol. 2025 Jan 15. Abstract
submitted by kickingbird at Jan, 17, 2025 from Nat Chem Biol. 2025 Jan 15 (via https://www.nature.com/articles/s41589-024-01813-z)
Manipulating viral protein stability using the cellular ubiquitin-proteasome system (UPS) represents a promising approach for developing live-attenuated vaccines. The first-generation proteolysis-targeting ... Shen J, Li J, Shen Q, Hou J, Zhang C, Bai H, Ai X,. Proteolysis-targeting influenza vaccine strains induce broad-spectrum immunity and in vivo protection. Nat Microbiol. 2025 Jan 15. Abstract
submitted by kickingbird at Jan, 17, 2025 from Nat Microbiol. 2025 Jan 15 (via https://www.nature.com/articles/s41564-024-01908-2)
Generating effective live vaccines from intact viruses remains challenging owing to considerations of safety and immunogenicity. Approaches that can be applied in a systematic manner are needed. Here we ... 9542 items, 20/Page, Page[60/478][|<<] [|<] [51] [52] [53] [54] [55] [56] [57] [58] [59] [60] [>|] [>>|] |
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