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2025-12-5 16:02:46
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Kwon, T., Trujillo, J. D., Carossino, M., Machkove. Pathogenicity and transmissibility of bovine-derived HPAI H5N1 B3.13 virus in pigs. Emerg Microbes Infect. 2025 May 21:2509742.  Abstract  
submitted by kickingbird at May, 22, 2025 from Emerg Microbes Infect. 2025 May 21:2509742 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Since the first emergence of highly pathogenic avian influenza (HPAI) H5N1 viruses in dairy cattle, the virus has continued to spread, reaching at least 17 states and at least 950 dairy herds in the United ...

Simmons HC, Finney J, Kotaki R, Adachi Y, Moseman. A protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface. mBio. 2025 May 20:e0089225.  Abstract  
submitted by kickingbird at May, 21, 2025 from mBio. 2025 May 20:e0089225 (via https://journals.asm.org/doi/10.1128/mbio.00892-25)
Influenza infection and vaccination impart strain-specific immunity that protects against neither seasonal antigenic variants nor the next pandemic. However, antibodies directed to conserved sites can ...

Yan C, Shi J, Cui P, Chen Y, Wang C, Wang Y, Miao. Characterization of emerging H3N3 avian influenza viruses in poultry in China. Emerg Microbes Infect. 2025 May 20:2509748.  Abstract  
submitted by kickingbird at May, 21, 2025 from Emerg Microbes Infect. 2025 May 20:2509748 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Avian influenza viruses continue to challenge poultry and human health; therefore, careful surveillance and evaluation of emerging viruses are important for animal disease control and human influenza pandemic ...

Zheng Z, Chen X, Zheng R, Yan Z, Li L, Chen R, Li. Progressive Adaptation of Subtype H6N1 Avian Influenza Virus in Taiwan Enhances Mammalian Infectivity, Pathogenicity, and Transmissibility. Viruses. 2025; 17(5):733.  Abstract  
submitted by kickingbird at May, 21, 2025 from Viruses. 2025; 17(5):733 (via https://www.mdpi.com/1999-4915/17/5/733)
The interspecies transmission of avian influenza viruses remains a significant public health concern. H6 viruses have gained attention following the first human infection by a chicken-origin H6N1 virus ...

Diefenbach-Elstob TR, Lay O, Zakis T, Deshpande N,. Report on influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza during 2023. Commun Dis Intell (2018). 2025 May 19;49.  Abstract  
submitted by kickingbird at May, 20, 2025 from Commun Dis Intell (2018). 2025 May 19;49 (via https://www1.health.gov.au/internet/main/publishing.nsf/Cont)
As part of its role in the World Health Organization's (WHO) Global Influenza Surveillance and Response System (GISRS), the WHO Collaborating Centre for Reference and Research on Influenza in Melbourne ...

Diego Carvalho do Nascimento, Mauricio Ulloa, Romu. [preprint]Chilean Avian flu and its marine impacts: an online Statistical Process Control task. https://doi.org/10.48550/arXiv.2505.08629.  Abstract  
submitted by kickingbird at May, 19, 2025 from https://doi.org/10.48550/arXiv.2505.08629 (via https://arxiv.org/abs/2505.08629)
The rapid spread of the HPAI H5N1 virus, responsible for the Avian Flu, is causing a great catastrophe on the South American Pacific coast (especially in the south of Peru and north of Chile). Although ...

You Chang, etc.,al. [preprint]Assessing the Spatial and Temporal Risk of HPAIV Transmission to Danish Cattle via Wild Birds. https://doi.org/10.48550/arXiv.2504.12432.  Abstract  
submitted by kickingbird at May, 19, 2025 from https://doi.org/10.48550/arXiv.2504.12432 (via https://arxiv.org/abs/2504.12432)
A highly pathogenic avian influenza (HPAI) panzootic has severely impacted wild bird populations worldwide, with documented (zoonotic) transmission to mammals, including humans. Ongoing HPAI outbreaks ...

Jason Matthiopoulos, etc.,al. [preprint]Multispecies HPAI spillovers led to the death of one-in-three breeding gannets. https://doi.org/10.21203/rs.3.rs-6589046/v1.  Abstract  
submitted by kickingbird at May, 19, 2025 from https://doi.org/10.21203/rs.3.rs-6589046/v1 (via https://www.researchsquare.com/article/rs-6589046/v1)
Emerging wildlife diseases, such as the recent global outbreak of Highly Pathogenic Avian Influenza, can devastate animal populations, yet identifying transmission pathways and true levels of mortality ...

Jonathan Heeney, etc.,al. [preprint]Digitally Immune-Optimised Next-Generation Influenza Vaccine Provides Cross-Clade Protection Against Emerging H5Nx Viruses. https://doi.org/10.21203/rs.3.rs-6647740/v1.  Abstract  
submitted by kickingbird at May, 19, 2025 from https://doi.org/10.21203/rs.3.rs-6647740/v1 (via https://www.researchsquare.com/article/rs-6647740/v1)
A panzootic of H5Nx avian influenza viruses has severely affected poultry and wild bird populations resulting in multiple mammalian spillovers, including human infections caused by antigenically distinct ...

Jatta, D., Wille, M., Ballmann, M. Z., Youm, B. N.,. Outbreak of high pathogenicity avian influenza (H5N1) in seabird populations of West Africa. Bird Study, 1–11.  Abstract  
submitted by kickingbird at May, 19, 2025 from Bird Study, 1–11 (via https://www.tandfonline.com/doi/full/10.1080/00063657.2025.2)
CapsuleAn outbreak of high pathogenicity avian influenza (HPAI) in 2023 caused mass wild bird mortalities in Senegal and The Gambia, heavily impacting seabirds.AimsTo present a comprehensive overview of ...

de Jong, S.P.J., Conlan, A.J.K., Han, A.X. et al. Competition between transmission lineages mediated by human mobility shapes seasonal influenza epidemics in the US. Nat Commun 16, 4605 (2025).  Abstract  
submitted by kickingbird at May, 19, 2025 from Nat Commun 16, 4605 (2025) (via https://www.nature.com/articles/s41467-025-59757-4)
Due to its climatic variability, complex mobility networks and geographic expanse, the United States represents a compelling setting to explore the transmission processes that lead to heterogeneous yearly ...

Andrea Arroyave, etc.,al. [preprint]Assessment of cross-reactive neutralizing antibodies induction against H5N1 clade 2.3.4.4b by prior seasonal influenza immunization in retail workers. https://doi.org/10.1101/2025.05.15.25327718.  Abstract  
submitted by kickingbird at May, 17, 2025 from https://doi.org/10.1101/2025.05.15.25327718 (via https://www.medrxiv.org/content/10.1101/2025.05.15.25327718v)
Highly pathogenic avian influenza (HPAI) H5N1 has been a global concern since its emergence in 1997, causing widespread outbreaks in birds and sporadic human infections. The clade 2.3.4.4b H5N1 virus has ...

K Wolfe, Amanda L. Bidwell, Stephen P. Hilton, Al. [preprint]Wastewater surveillance for avian influenza: national patterns of detection and relationship with reported outbreaks and infections. https://doi.org/10.1101/2025.05.06.25327100.  Abstract  
submitted by kickingbird at May, 17, 2025 from https://doi.org/10.1101/2025.05.06.25327100 (via https://www.medrxiv.org/content/10.1101/2025.05.06.25327100v)
Background Influenza A virus (IAV) is a major cause of morbidity and mortality globally, causing seasonal influenza in humans and infecting birds and some mammals. In 2024, IAV H5N1 highly pathogenic avian ...

Hu W, Liu Y, Dong J, Peng X, Yang C, Wang H, Chen. Evaluation of a Machine Learning Model Based on Laboratory Parameters for the Prediction of Influenza A and B in Chongqing, China: Multicenter Model Development and Validation Study. J Med Internet Res. 2025 May 15;27:e67847.  Abstract  
submitted by kickingbird at May, 17, 2025 from J Med Internet Res. 2025 May 15;27:e67847 (via https://www.jmir.org/2025/1/e67847)
Background: Influenza viruses are major pathogens responsible for acute respiratory infections in humans, which present with symptoms such as fever, cough, sore throat, muscle pain, and fatigue. While ...

Páez-Hernández ZY, Stephano-Hornedo JL, Bola?os-Pr. Neutralization of the Pandemic Influenza A/H1N1 Virus with Lama glama Humanized Nanobodies (VHH). Antibodies. 2025; 14(2):42.  Abstract  
submitted by kickingbird at May, 17, 2025 from Antibodies. 2025; 14(2):42 (via https://www.mdpi.com/2073-4468/14/2/42)
Background/Objetives: Nanobodies (VHH) have become an excellent tool for diagnosis, therapy, and research since VHH shows a high capability of recognizing and neutralizing antigens. VHHs are highly soluble ...

Bonilla-Aldana DK, Bonilla-Aldana JL, Acosta-Espa?. Highly Pathogenic Avian Influenza H5N1 in Cats (Felis catus): A Systematic Review and Meta-Analysis. Animals. 2025; 15(10):1441.  Abstract  
submitted by kickingbird at May, 17, 2025 from Animals. 2025; 15(10):1441 (via https://www.mdpi.com/2076-2615/15/10/1441)
Introduction: Highly pathogenic avian influenza (HPAI) H5N1, a zoonotic virus primarily affecting birds, has shown increasing cross-species transmission, including to domestic animals such as cats. Recent ...

Eggink Dirk, Kroneman Annelies, Dingemans Jozef, G. Human infections with Eurasian avian-like swine influenza virus detected by coincidence via routine respiratory surveillance systems, the Netherlands, 2020 to 2023. Euro Surveill. 2025;30(19):pii=2400662.  Abstract  
submitted by kickingbird at May, 17, 2025 from Euro Surveill. 2025;30(19):pii=2400662 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Sporadic human infections with avian or swine influenza A virus (swIAV) have been reported. Zoonotic influenza, including human infections with avian influenza A virus or swIAV, is notifiable in the Netherlands ...

Ruchao Peng et al. Molecular basis of influenza ribonucleoprotein complex assembly and processive RNA synthesis. Science388,eadq7597(2025).  Abstract  
submitted by kickingbird at May, 16, 2025 from Science388,eadq7597(2025) (via https://www.science.org/doi/10.1126/science.adq7597)
INTRODUCTIONInfluenza virus poses a long-standing public health issue worldwide, causing both recurring seasonal flu and occasional pandemics in humans and other animals. Current vaccines and antivirals ...

Manman Dai, etc.,al. Chicken TCRγδ+CD8α+T cells are antigen-specific and protective in H9N2 AIV infection. The Journal of Immunology, vkaf083.  Abstract  
submitted by kickingbird at May, 16, 2025 from The Journal of Immunology, vkaf083 (via https://academic.oup.com/jimmunol/advance-article-abstract/d)
TCRγδ+ T cells are a major lymphocyte population of chickens, but their response or contribution to immunity against avian influenza virus (AIV) remains unknown. Here, we report an increase in the proportion ...

Stevenson-Leggett P, Adams L, Greenwood D, Lofts A. Investigation of Influenza A(H5N1) Virus Neutralization by Quadrivalent Seasonal Vaccines, United Kingdom, 2021–2024. Emerg Infect Dis. 2025 Jun.  Abstract  
submitted by kickingbird at May, 15, 2025 from Emerg Infect Dis. 2025 Jun (via https://wwwnc.cdc.gov/eid/article/31/6/24-1796_article)
We tested cross-neutralization against highly pathogenic avian influenza A(H5N1) virus in adults vaccinated with 2021–2023 seasonal quadrivalent influenza vaccine in the United Kingdom. Seasonal quadrivalent ...

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