El-Shall NA, Abd El Naby WSH, Hussein EGS, Yonis A. Pathogenicity of H5N8 avian influenza virus in chickens and in duck breeds and the role of MX1 and IFN-α in infection outcome and transmission to contact birds. Comp Immunol Microbiol Infect Dis. 2023 Aug 3;100:. Abstract
submitted by kickingbird at Aug, 21, 2023 from Comp Immunol Microbiol Infect Dis. 2023 Aug 3;100: (via https://www.sciencedirect.com/science/article/abs/pii/S01479)
This study examined the pathogenicity, immunogenicity, and transmission potential of the H5N8 HPAI clade 2.3.4.4b virus in three breeds of ducks and in broiler chickens. Chickens, Muscovy, Pekin, and Mallard ... Cronk BD, Caserta LC, Laverack M, Gerdes RS, Hynes. Infection and tissue distribution of Highly Pathogenic Avian Influenza A type H5N1 (clade 2.3.4.4b) in Red Fox kits ( Vulpes vulpes). Emerg Microbes Infect . 2023 Aug 17;2249554. Abstract
submitted by kickingbird at Aug, 17, 2023 from Emerg Microbes Infect . 2023 Aug 17;2249554 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Avian influenza H5N1 is a highly pathogenic virus that primarily affects birds. However, it can also infect other animal species, including mammals. We report the infection of nine juvenile red foxes (Vulpes ... Li J, Fang Y, Qiu X, Yu X, Cheng S, Li N, Sun Z, N. Human infection with avian-origin H5N6 influenza a virus after exposure to slaughtered poultry. Emerg Microbes Infect. 2022 Dec;11(1):807-810. Abstract
submitted by kickingbird at Aug, 17, 2023 from Emerg Microbes Infect. 2022 Dec;11(1):807-810 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2022.2)
Exposure to poultry in live poultry markets is strongly associated with human infection with avian influenza virus. To effectively prevent the transmission of viruses from live poultry to humans, people ... Zhang L, Liu K, Su Q, Chen X, Wang X, Li Q, Wang W. Clinical features of the first critical case of acute encephalitis caused by the avian influenza A (H5N6) virus. Emerg Microbes Infect. 2022 Dec;11(1):2437-2446. Abstract
submitted by kickingbird at Aug, 17, 2023 from Emerg Microbes Infect. 2022 Dec;11(1):2437-2446 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2022.2)
Highly pathogenic avian influenza viruses (HPAIV), such as H5N1, H5N6, and H7N9, have been reported to frequently infect humans, but acute encephalitis caused by HPAIV in humans has been rarely reported. ... Bergant V, Schnepf D, de Andrade Kr?tzig N, Hubel. mRNA 3´UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus. Nat Commun. 2023 Aug 15;14(1):4906. Abstract
submitted by kickingbird at Aug, 17, 2023 from Nat Commun. 2023 Aug 15;14(1):4906 (via https://www.nature.com/articles/s41467-023-40469-6)
Changes of mRNA 3'UTRs by alternative polyadenylation (APA) have been associated to numerous pathologies, but the mechanisms and consequences often remain enigmatic. By combining transcriptomics, proteomics ... Wang X, Liu K, Guo Y, Pei Y, Chen X, Lu X, Gao R,. Emergence of a new designated clade 16 with significant antigenic drift in hemagglutinin gene of H9N2 subtype avian influenza virus in eastern China. Emerg Microbes Infect. 2023 Aug 16:2249558. Abstract
submitted by kickingbird at Aug, 17, 2023 from Emerg Microbes Infect. 2023 Aug 16:2249558 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
H9N2 avian influenza viruses (AIVs) pose an increasing threat to the poultry industry worldwide and have pandemic potential. Vaccination has been principal prevention strategy to control H9N2 in China ... Huang X, Cai Y, Yin G, Chen Z, Hu J, Gao Z, Guo X,. Identification of catalytically active domain epitopes in neuraminidase protein of H9N2 subtype of avian influenza virus. Avian Pathol. 2023 Aug 15:1-11. Abstract
submitted by kickingbird at Aug, 16, 2023 from Avian Pathol. 2023 Aug 15:1-11 (via https://www.tandfonline.com/doi/abs/10.1080/03079457.2023.22)
H9N2 subtype of avian influenza virus (AIV) is primarily a bird virus, which is widespread in clinical avian disease, and reported in cases of human infection. As one of the surface proteins of AIV, the ... Xia J, Li YX, Dong MY, Guo ZW, Luo YW, Li NL, Zhao. Evolution of prevalent H9N2 subtype of avian influenza virus during 2019 to 2022 for the development of a control strategy in China. Poult Sci. 2023 Jul 25;102(10):102957. Abstract
submitted by kickingbird at Aug, 16, 2023 from Poult Sci. 2023 Jul 25;102(10):102957 (via https://www.sciencedirect.com/science/article/pii/S003257912)
The H9N2 subtype of avian influenza virus (H9N2 AIV) has caused significant losses in chicken flocks throughout China. At present, consensus has been reached that field isolates of H9N2 underwent antigenic ... Youk S, Torchetti MK, Lantz K, Lenoch JB, Killian. H5N1 highly pathogenic avian influenza clade 2.3.4.4b in wild and domestic birds: Introductions into the United States and reassortments, December 2021-April 2022. Virology. 2023 Aug 2;587:109860. Abstract
submitted by kickingbird at Aug, 14, 2023 from Virology. 2023 Aug 2;587:109860 (via https://www.sciencedirect.com/science/article/pii/S004268222)
Highly pathogenic avian influenza viruses (HPAIVs) of the A/goose/Guangdong/1/1996 lineage H5 clade 2.3.4.4b continue to have a devastating effect on domestic and wild birds. Full genome sequence analyses ... Kok A, Scheuer R, Bestebroer TM, Burke DF, Wilks S. Characterization of A/H7 influenza virus global antigenic diversity and key determinants in the hemagglutinin globular head mediating A/H7N9 antigenic evolution. mBio. 2023 Aug 11:e0048823. Abstract
submitted by kickingbird at Aug, 12, 2023 from mBio. 2023 Aug 11:e0048823 (via https://journals.asm.org/doi/10.1128/mbio.00488-23)
Avian A/H7 influenza viruses are a global threat to animal and human health. These viruses continue to cause outbreaks in poultry and have caused the highest number of reported zoonotic infections to date, ... Zhuang Y, Wang M, Liang L, Mao Y, Wang K, Yang S,. The first known human death after infection with the avian influenza (A/H3N8) virus: Guangdong Province, China, March 2023. Clin Infect Dis. 2023 Aug 9:ciad462. Abstract
submitted by kickingbird at Aug, 10, 2023 from Clin Infect Dis. 2023 Aug 9:ciad462 (via https://academic.oup.com/cid/advance-article/doi/10.1093/cid)
We reported a case of human infection with the H3N8 avian influenza virus, who had multiple myeloma and died of severe infection. Genome analysis showed multiple gene mutations and reassortments without ... Thomas SN, Niemeyer BF, Jimenez-Valdes RJ, Kaiser. Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection. iScience. 2023 Jul 14;26(8):107361. Abstract
submitted by kickingbird at Aug, 10, 2023 from iScience. 2023 Jul 14;26(8):107361 (via https://www.cell.com/iscience/fulltext/S2589-0042(23)01438-4)
Individuals with Down syndrome (DS) clinically manifest severe respiratory illnesses; however, there is a paucity of data on how DS influences homeostatic physiology of lung airway, and its reactive responses ... Tonouchi K, Adachi Y, Suzuki T, Kuroda D, Nishiyam. Structural basis for cross-group recognition of an influenza virus hemagglutinin antibody that targets postfusion stabilized epitope. PLoS Pathog. 2023 Aug 9;19(8):e1011554. Abstract
submitted by kickingbird at Aug, 10, 2023 from PLoS Pathog. 2023 Aug 9;19(8):e1011554 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Plasticity of influenza virus hemagglutinin (HA) conformation increases an opportunity to generate conserved non-native epitopes with unknown functionality. Here, we have performed an in-depth analysis ... Xie Q, Liao X, Huang B, Wang L, Liao G, Luo C, Wen. The truncated IFITM3 facilitates the humoral immune response in inactivated influenza vaccine-vaccinated mice via interaction with CD81. Emerg Microbes Infect. 2023 Aug 9:2246599. Abstract
submitted by kickingbird at Aug, 10, 2023 from Emerg Microbes Infect. 2023 Aug 9:2246599 (via https://pubmed.ncbi.nlm.nih.gov/37556756/)
A single-nucleotide polymorphism (SNP) rs12252-C of interferon-induced transmembrane protein 3 (IFITM3), resulting in a truncated IFITM3 protein lacking 21 N-terminus amino acids, is associated with severe ... Zhang N, Quan K, Chen Z, Hu Q, Nie M, Xu N, Gao R,. The emergence of new antigen branches of H9N2 avian influenza virus in China due to antigenic drift on hemagglutinin through antibody escape at immunodominant sites. Emerg Microbes Infect. 2023 Aug 7:2246582. Abstract
submitted by kickingbird at Aug, 9, 2023 from Emerg Microbes Infect. 2023 Aug 7:2246582 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Vaccination is a crucial prevention and control measure against H9N2 avian influenza viruses (AIVs) that threaten poultry production and public health. However, H9N2 AIVs in China undergo continuous antigenic ... Zeller MA, Ma J, Wong FY, Tum S, Hidano A, Holt H,. The genomic landscape of swine influenza A viruses in Southeast Asia. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230. Abstract
submitted by kickingbird at Aug, 9, 2023 from Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230 (via https://www.pnas.org/doi/10.1073/pnas.2301926120)
Swine are a primary source for the emergence of pandemic influenza A viruses. The intensification of swine production, along with global trade, has amplified the transmission and zoonotic risk of swine ... Tsang TK, Wang C, Fang VJ, Perera RAPM, So HC, Ip. Reconstructing household transmission dynamics to estimate the infectiousness of asymptomatic influenza virus infections. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230. Abstract
submitted by kickingbird at Aug, 8, 2023 from Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230 (via https://www.pnas.org/doi/10.1073/pnas.2304750120)
There has long been controversy over the potential for asymptomatic cases of the influenza virus to have the capacity for onward transmission, but recognition of asymptomatic transmission of COVID-19 stimulates ... Yang Y, Huang Y, Huang K, Zhang Y, Hu X, Zou W, Wu. Isolation and identification of Eurasian avian-like H1N1 swine influenza virus and evaluation of their pathogenicity and immune protective effects in pigs. Vet Microbiol. 2023 Jul 12;284:109827. Abstract
submitted by kickingbird at Aug, 7, 2023 from Vet Microbiol. 2023 Jul 12;284:109827 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Swine influenza (SI) is a severe disease affecting pigs, with a huge economic impact on pig farmers. Currently, available SIV vaccines do not meet the requirements for Swine influenza prevention and control, ... Xu S, Yu L, Teng Q, Li X, Jin Z, Qu Y, Li J, Zhang. Enhance immune response to H9 AIV DNA vaccine based on polygene expression and DGL nanoparticle encapsulation. Poult Sci. 2023 Jul 6;102(10):102925. Abstract
submitted by kickingbird at Aug, 7, 2023 from Poult Sci. 2023 Jul 6;102(10):102925 (via https://www.sciencedirect.com/science/article/pii/S003257912)
DNA vaccination has great potential to treat or prevent avian influenza pandemics, but the technique may be limited by low immunogenicity and gene delivery in clinical testing. Here, to improve the immune ... Thompson D, Cismaru CV, Rougier JS, Schwemmle M, Z. The M2 proteins of bat influenza A viruses reveal atypical features compared to conventional M2 proteins. J Virol. 2023 Aug 4:e0038823. Abstract
submitted by kickingbird at Aug, 5, 2023 from J Virol. 2023 Aug 4:e0038823 (via https://journals.asm.org/doi/10.1128/jvi.00388-23)
The influenza A virus (IAV) M2 protein has proton channel activity, which plays a role in virus uncoating and may help to preserve the metastable conformation of the IAV hemagglutinin (HA). In contrast ... 7538 items, 20/Page, Page[26/377][|<<] [|<] [21] [22] [23] [24] [25] [26] [27] [28] [29] [30] [>|] [>>|] |
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