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2025-12-5 15:25:12
Article

Yuying Liang, Jian Chen, Shiyun Ma, Haoru Song, Da. Ultrafast Tyrosinase-Mediated Biotinylation of Living Cell Surface Analysis Reveals Novel Cell Surface Proteins Responsible for Influenza A Virus Entry. Journal of the American Chemical Society.  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Journal of the American Chemical Society (via https://pubs.acs.org/doi/10.1021/jacs.5c12360)
Cell surface proteins are integral to a myriad of biological processes, including cell–cell interactions, signal transduction, and cell adhesion. Notably, these proteins also serve as key receptors for ...

Brenda Aline Maya Badillo, etc.,al. H5N1 highly pathogenic avian influenza vaccination: Seroresponse of mexican poultry in the 2022-2024. Vaccine: X, 23 Aug 2025, 100709.  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Vaccine: X, 23 Aug 2025, 100709 (via https://www.sciencedirect.com/science/article/pii/S259013622)
Since 2021, the activity and impact of the highly pathogenic H5N1 avian influenza virus have intensified worldwide, causing high mortality in wild birds and birds while also infecting various wild and ...

Anika John, etc.,al. Characterizing Influenza A Virus Lineages and Clinically Relevant Mutations Through High-Coverage Wastewater Sequencing. Water Research. 21 Aug 2025, 124453.  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Water Research. 21 Aug 2025, 124453 (via https://www.sciencedirect.com/science/article/pii/S004313542)
Influenza A virus poses significant public health challenges, causing seasonal outbreaks and pandemics. Its rapid evolution motivates continuous monitoring of circulating influenza genomes to inform vaccine ...

Shengjun Bu, etc.,al. A lateral flow biosensor based on a novel isothermal amplification method for visual identification of the influenza virus H1N1. Microchemical Journal. 21 Aug 2025, 114953.  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Microchemical Journal. 21 Aug 2025, 114953 (via https://www.sciencedirect.com/science/article/abs/pii/S00262)
Here, we developed a novel single primer-amplification (SPA) method for detection of nucleic acids that requires only two primers and one enzyme. The primer was extended into long ssDNA products with tandem ...

Paran, N., Wirblich, C., Olal, C. et al. Immunogenicity and safety of a rabies-based highly pathogenic influenza A virus H5 vaccine in cattle. npj Vaccines 10, 197 (2025).  Abstract  
submitted by kickingbird at Aug, 24, 2025 from npj Vaccines 10, 197 (2025) (via https://link.springer.com/article/10.1038/s41541-025-01238-2)
The circulation of highly pathogenic H5 influenza A viruses in cattle, other mammals, and wildlife threatens animal and human health. To address this, we vaccinated heifer-calves with a deactivated rabies-virus-based ...

Hu, M., Luo, N., Wang, B. et al. Flu-CNN: identifying host specificity of Influenza A virus using convolutional networks. Hum Genomics 19, 96 (2025).  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Hum Genomics 19, 96 (2025) (via https://link.springer.com/article/10.1186/s40246-025-00812-y)
Influenza A viruses (IAVs) have historically posed significant public health threats, causing severe pandemics. Viral host specificity is typically constrained by host barriers, limiting the range of species ...

Piltch-Loeb, R., Gibbs, S.G., Lowe, J.J. et al. U.S. trust in physicians as key public health messengers during the H5N1 avian influenza outbreak. Sci Rep 15, 31011 (2025).  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Sci Rep 15, 31011 (2025) (via https://link.springer.com/article/10.1038/s41598-025-12304-z)
The emerging threat of H5N1 avian influenza in humans has renewed the need for effective public health communication strategies, especially in light of reduced public trust in governmental institutions. ...

Arroyave A, Rabezanahary H, Wantchecon A, Rahajama. Assessment of Cross-Reactive Neutralizing Antibodies Induction Against H5N1 Clade 2.3.4.4b by Prior Seasonal Influenza Immunization in Retail Workers. Open Forum Infect Dis. 2025 Aug 20;12(8):ofaf463.  Abstract  
submitted by kickingbird at Aug, 23, 2025 from Open Forum Infect Dis. 2025 Aug 20;12(8):ofaf463 (via https://academic.oup.com/ofid/article/12/8/ofaf463/8238501)
This study evaluated whether immunity from seasonal influenza induces cross-reactive antibodies against recent avian and bovine H5N1 strains in serum from retail workers. Despite strong neutralizing activity ...

Ramya S. Barre, etc.,al. A Human H5N1 Influenza Virus Expressing Bioluminescence for Evaluating Viral Infection and Identifying Therapeutic Interventions. iScience. 21 Aug 2025, 113402.  Abstract  
submitted by kickingbird at Aug, 23, 2025 from iScience. 21 Aug 2025, 113402 (via https://www.sciencedirect.com/science/article/pii/S258900422)
A multistate outbreak of highly pathogenic avian influenza virus (HPAIV) H5N1 in the United States dairy cattle was first reported on March 2024, followed by a zoonotic cattle-to-human virus transmission ...

Rehman, S., Ullah, S., Zaman, A., Ashraf, U., Mali. Tracking the phylogeography of H5N1 Highly pathogenic avian influenza viruses in Indonesia (2003-2024). World’s Poultry Science Journal, 1–23.  Abstract  
submitted by kickingbird at Aug, 23, 2025 from World’s Poultry Science Journal, 1–23 (via https://www.tandfonline.com/doi/full/10.1080/00439339.2025.2)
Indonesia has experienced HPAI H5N1 outbreaks since 2003, with its first human case detected in 2005. This study investigates the phylogeography and genetic evolution of highly pathogenic avian influenza ...

Buttinger Gerhard, Petrillo Mauro, Valastro Vivian. Novel (d)PCR assays for influenza A(H5Nx) viruses clade 2.3.4.4b surveillance. Euro Surveill. 2025;30(33):pii=2500183.  Abstract  
submitted by kickingbird at Aug, 23, 2025 from Euro Surveill. 2025;30(33):pii=2500183 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Avian influenza is a highly contagious respiratory viral infection of birds caused by influenza A viruses (AIVs). Most AIVs are designated as low pathogenicity viruses and are maintained by wild waterfowl ...

William T. Harvey, etc.,al. [preprint]Genetic reassortment and diversification of host specificity have driven evolutionary trajectories of lineages of panzootic H5N1 influenza. https://doi.org/10.1101/2025.08.20.670882.  Abstract  
submitted by kickingbird at Aug, 23, 2025 from https://doi.org/10.1101/2025.08.20.670882 (via https://www.biorxiv.org/content/10.1101/2025.08.20.670882v1)
Since 2021, subclade 2.3.4.4b A(H5N1) high pathogenicity avian influenza (HPAI) viruses have undergone changes in ecology and epidemiology, causing a panzootic of unprecedented scale in wild and domestic ...

Xingdong Song, etc.,al. Prevalence and Transmission of Influenza A (H6) Viruses Pose a Potential Threat to Public Health. Journal of Infection.  Abstract  
submitted by kickingbird at Aug, 20, 2025 from Journal of Infection (via https://www.sciencedirect.com/science/article/pii/S016344532)
On March 25, 2024, the clade 2.3.4.4b highly pathogenic influenza H5N1 virus infection was reported in dairy cattle in Texas, USA. As of June 7, 2025, outbreaks of H5N1 virus occurred in more than 1000 ...

Bassit L, Damhorst GL, Bowers HB, Sabino C, Sulliv. Toward diagnostic preparedness: detection of highly pathogenic avian influenza A(H5N1) in contrived nasal swab specimens using rapid antigen and point-of-care molecular tests. J Clin Microbiol 0:e00548-25.  Abstract  
submitted by kickingbird at Aug, 20, 2025 from J Clin Microbiol 0:e00548-25 (via https://journals.asm.org/doi/10.1128/jcm.00548-25)
Highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b was first detected in birds in 2021 in the United States (U.S.). An ongoing outbreak in dairy cattle began in early 2024 involving genotype ...

WPRO. Avian Influenza Weekly Update # 1010: 15 August 2025. WHO.  Abstract  
submitted by kickingbird at Aug, 19, 2025 from WHO (via https://cdn.who.int/media/docs/default-source/wpro---documen)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ...

Badr C, Arbi M, Souiai O, Larbi I, Nsiri J, Elbehi. Tracing the 2021 equine influenza Outbreak: First characterization and phylogeographic analysis of H3N8 Florida clade 1 virus in Tunisia. Virology. 2025 Aug 12;611:110655.  Abstract  
submitted by kickingbird at Aug, 19, 2025 from Virology. 2025 Aug 12;611:110655 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Equine influenza (EI) is a highly contagious viral respiratory disease affecting equids, with the potential of causing widespread outbreaks across Europe, the Americas, Asia, and other regions of the world. ...

Yin S, Zhang C, Teitelbaum CS, Si Y, Zhang G, Wang. Landscape changes elevate the risk of avian influenza virus diversification and emergence in the East Asian-Australasian Flyway. PNAS 2025 Aug 26;122(34):e2503427122.  Abstract  
submitted by kickingbird at Aug, 19, 2025 from PNAS 2025 Aug 26;122(34):e2503427122 (via https://www.pnas.org/doi/10.1073/pnas.2503427122)
Highly pathogenic avian influenza viruses (HPAIV) persistently threaten wild waterfowl, domestic poultry, and public health. The East Asian-Australasian Flyway plays a crucial role in HPAIV dynamics due ...

Restrepo Munera J, Riccio-Baum C, Kaddis Maldonado. Germinal Center B cells provide essential IL-1β signals to TFH cells via canonical NLRP3 inflammasome activity post influenza infection. PLoS Pathog. 2025 Aug 18;21(8):e1013404.  Abstract  
submitted by kickingbird at Aug, 19, 2025 from PLoS Pathog. 2025 Aug 18;21(8):e1013404 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Persistent germinal center (GC) responses show increased benefit in optimal responses to influenza infection. Follicular helper T (TFH) cells provide the essential signals and help for maintenance of GCs ...

Saeidi S, Wan H, Kang H, Gao J, Wu WW, Malik T, Da. N-linked glycans on the stalk of influenza virus neuraminidase promote functional tetramer formation by compensating for local hydrophobicity. J Virol. 2025 Aug 18:e0087925.  Abstract  
submitted by kickingbird at Aug, 19, 2025 from J Virol. 2025 Aug 18:e0087925 (via https://journals.asm.org/doi/10.1128/jvi.00879-25)
Enveloped virus surface antigens, such as influenza neuraminidase (NA), typically depend on N-linked glycans for assembly, trafficking in the host cell, and immune evasion. Here, we examined the function ...

Basu Thakur P, Bullock HA, Stevens J, Kumar A, Mai. Heterogeneity across mammalian- and avian-origin A(H1N1) influenza viruses influences viral infectivity following incubation with host bacteria from the human respiratory tract. Microbiol Spectr. 2025 Aug 18:e0097725.  Abstract  
submitted by kickingbird at Aug, 19, 2025 from Microbiol Spectr. 2025 Aug 18:e0097725 (via https://journals.asm.org/doi/10.1128/spectrum.00977-25)
Influenza A viruses (IAVs) are primarily transmitted between mammals by the respiratory route and encounter bacteria in the respiratory tract before infecting susceptible epithelial cells. Previous studies ...

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