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ini H, Ghalyanchilangeroudi A, Fallah Mehrabadi MH. Phylogenetic analysis of H9N2 avian influenza viruses in Afghanistan (2016-2017). Arch Virol. 2017..  Abstract  
submitted by kickingbird at Jul, 10, 2017 from Arch Virol. 2017. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28674864/)
Avian influenza A virus (AIV) subtype H9N2 is the most prevalent subtype found in terrestrial poultry throughout Eurasia and has been isolated from poultry outbreaks worldwide. Tracheal tissue specimens ...

Kang M, Lau EHY, Guan W, Yang Y, Song T, Cowling B. Epidemiology of human infections with highly pathogenic avian influenza A(H7N9) virus in Guangdong, 2016 to 2017. Euro Surveill. 2017;22(27):pii=30568.  Abstract  
submitted by kickingbird at Jul, 7, 2017 from Euro Surveill. 2017;22(27):pii=30568 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
We describe the epidemiology of highly pathogenic avian influenza (HPAI) A(H7N9) based on poultry market environmental surveillance and laboratory-confirmed human cases (n?=?9) in Guangdong, ...

Shubhada K. Chothe, Gitanjali Bhushan, etc.,al. Avian and human influenza virus compatible sialic acid receptors in little brown bats. Scientific Reports 7, Article number: 660 (2017).  Abstract  
submitted by kickingbird at Jul, 7, 2017 from Scientific Reports 7, Article number: 660 (2017) (via http://www.nature.com/articles/s41598-017-00793-6)
Influenza A viruses (IAVs) continue to threaten animal and human health globally. Bats are asymptomatic reservoirs for many zoonotic viruses. Recent reports of two novel IAVs in fruit bats and serological ...

Rouphael NG, Paine M, Mosley R, Henry S, et al. The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial. Lancet 2017 Jun 27..  Abstract  
submitted by kickingbird at Jul, 3, 2017 from Lancet 2017 Jun 27. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28666680/)
BACKGROUND: Microneedle patches provide an alternative to conventional needle-and-syringe immunisation, and potentially offer improved immunogenicity, simplicity, cost-effectiveness, acceptability, and ...

Venereo-Sanchez A, Simoneau M, Lanthier S, Chahal. Process intensification for high yield production of influenza H1N1 Gag virus-like particles using an inducible HEK-293 stable cell line. Vaccine 2017 Jun 22.  Abstract  
submitted by kickingbird at Jul, 3, 2017 from Vaccine 2017 Jun 22 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28648546/)
Influenza virus dominant antigens presentation using virus like particle (VLP) approach is attractive for the development of new generation of influenza vaccines. Mammalian cell platform offers many advantages ...

Diaz A, Marthaler D, Culhane M, Sreevatsan S, et a. Complete Genome Sequencing of Influenza A Viruses within Swine Farrow-to-Wean Farms Reveals the Emergence, Persistence, and Subsidence of Diverse Viral Genotypes. J Virol 2017 Jun 28.  Abstract  
submitted by kickingbird at Jul, 3, 2017 from J Virol 2017 Jun 28 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28659482/)
Influenza A viruses (IAVs) are endemic in swine and represent a public health risk. However, there is limited information on the genetic diversity of swine IAVs within farrow-to-wean farms, which is where ...

Nam JH, Shim SM, Song EJ, Espano E, et al. Rapid virulence shift of an H5N2 avian influenza virus during a single passage in mice. Arch Virol 2017 Jun 29.  Abstract  
submitted by kickingbird at Jul, 3, 2017 from Arch Virol 2017 Jun 29 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28664296/)
Influenza A viruses must undergo adaptation to acquire virulence in new host species. In mouse models, host adaptation for virulence is generally performed through 5 to 20 lung-to-lung passages. However, ...

Jiang wenming, etc.,al. Analysis of Swan H5N8 Avian Influenza in Holy Lake of Shanxi Province and the Current Virus Lingeage of H5 Subtype Avian Influenza. Sinovet 2017 Vol 34.  Abstract  
submitted by kickingbird at Jul, 1, 2017 from Sinovet 2017 Vol 34
Abstract:In December 2016,18 white swans died in the scenic area of Holy Lake in Ruicheng county of Shanxiprovince. It was confirmed that the outbreak was caused by the H5N8 subtype highly pathogenic avian ...

Smith GE, Sun X, Bai Y, Liu YV, et al.. Neuraminidase-based recombinant virus-like particles protect against lethal avian influenza A(H5N1) virus infection in ferrets. Virology 2017;509:90-97.  Abstract  
submitted by kickingbird at Jun, 27, 2017 from Virology 2017;509:90-97 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28624679/)
Avian influenza A (H5N1) viruses represent a growing threat for an influenza pandemic. The presence of widespread avian influenza virus infections further emphasizes the need for vaccine strategies for ...

Patel H, Kukol A.. Evolutionary conservation of influenza A PB2 sequences reveals potential target sites for small molecule inhibitors. Virology 2017;509:112-120..  Abstract  
submitted by kickingbird at Jun, 27, 2017 from Virology 2017;509:112-120. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28628827/)
The influenza A basic polymerase protein 2 (PB2) functions as part of a heterotrimer to replicate the viral RNA genome. To investigate novel PB2 antiviral target sites, this work identified evolutionary ...

Chlanda P. Influenza Hemagglutinin and M2 ion channel priming by trypsin: Killing two birds with one stone. Virology 2017;509:131-132.  Abstract  
submitted by kickingbird at Jun, 27, 2017 from Virology 2017;509:131-132 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28644977/)
Influenza A virus membrane fusion and disassembly, prerequisite processes for viral infectivity, depend on acidic pH. In a recent study, Zhirnov et al. reported an important finding-that influenza virions ...

Sikora D, Rocheleau L, Brown EG, Pelchat M, et al. Influenza A virus cap-snatches host RNAs based on their abundance early after infection. Virology 2017;509:167-177.  Abstract  
submitted by kickingbird at Jun, 27, 2017 from Virology 2017;509:167-177 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28646652/)
The influenza A virus RNA polymerase cleaves the 5' ends of host RNAs and uses these RNA fragments as primers for viral mRNA synthesis. We performed deep sequencing of the 5' host-derived ends of the eight ...

Nogales A, Rodriguez L, DeDiego ML, Topham DJ, et. Interplay of PA-X and NS1 proteins in replication and pathogenesis of a temperature-sensitive 2009 pandemic H1N1 influenza A virus. J Virol 2017 Jun 21.  Abstract  
submitted by kickingbird at Jun, 27, 2017 from J Virol 2017 Jun 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28637750/)
Influenza A viruses (IAVs) cause seasonal epidemics and occasional pandemics, representing a serious public health concern. It has been described that one mechanism used by some IAV strains to escape the ...

Clark AM, Nogales A, Martinez-Sobrido L, Topham DJ. Functional evolution of influenza NS1 protein in currently circulating human 2009 pandemic H1N1 viruses. J Virol 2017 Jun 21.  Abstract  
submitted by kickingbird at Jun, 27, 2017 from J Virol 2017 Jun 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28637754/)
In 2009, a novel H1N1 influenza virus emerged in humans, causing a global pandemic. It was previously shown that the NS1 protein from this human 2009 pandemic H1N1 (pH1N1) virus was an effective interferon ...

Wang Y, Li T, Chen Y, Wei H, et al. Involvement of NK Cells in IL-28B-Mediated Immunity against Influenza Virus Infection. J Immunol 2017 Jun 21.  Abstract  
submitted by kickingbird at Jun, 27, 2017 from J Immunol 2017 Jun 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28637903/)
IL-28B is a member of the newly discovered type III IFN family and exhibits unique antiviral properties compared with other family members. NK cells play a critical role in defending against viruses; however, ...

Ducatez M, et al. Highly pathogenic avian influenza H5N1 clade 2.3.2.1 and clade 2.3.4 viruses do not induce a clade-specific phenotype in mallard ducks. J Gen Virol 2017 Jun 20.  Abstract  
submitted by kickingbird at Jun, 27, 2017 from J Gen Virol 2017 Jun 20 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28631606/)
Among the diverse clades of highly pathogenic avian influenza (HPAI) H5N1 viruses of the goose/Guangdong lineage, only a few have been able to spread across continents: clade 2.2 viruses spread from China ...

Kesavardhana S, Kuriakose T, Guy CS, Samir P, et a. ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death. J Exp Med 2017 Jun 20.  Abstract  
submitted by kickingbird at Jun, 27, 2017 from J Exp Med 2017 Jun 20 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28634194/)
Innate sensing of influenza virus infection induces activation of programmed cell death pathways. We have recently identified Z-DNA-binding protein 1 (ZBP1) as an innate sensor of influenza A virus (IAV). ...

Moatasim Y, Kandeil A, Mostafa A, Elghaffar SKA, e. Single gene reassortment of highly pathogenic avian influenza A H5N1 in the low pathogenic H9N2 backbone and its impact on pathogenicity and infectivity of novel reassortant viruses. Arch Virol 2017 Jun 15..  Abstract  
submitted by kickingbird at Jun, 27, 2017 from Arch Virol 2017 Jun 15. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28620809/)
Avian influenza A H5N1 and H9N2 viruses have been extensively circulating in various avian species and frequently infect mammals, including humans. The synchronous circulation of both viruses in Egypt ...

Liu M, Lo EC, Wang G, Chow HF, et al. Identification of influenza polymerase inhibitors targeting polymerase PB2 cap-binding domain through virtual screening. Antiviral Res 2017 Jun 16. pii: S0166-3542(16)3058.  Abstract  
submitted by kickingbird at Jun, 27, 2017 from Antiviral Res 2017 Jun 16. pii: S0166-3542(16)3058 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28629986/)
Influenza A virus is the major cause of epidemics and pandemics worldwide. In this study, virtual screening was used to identify compounds interacting with influenza A polymerase PB2 cap-binding domain ...

Paul SS, Mok CK, Mak TM, Ng OW, et al. A cross-clade H5N1 influenza A virus neutralizing monoclonal antibody binds to a novel epitope within the vestigial esterase domain of hemagglutinin. Antiviral Res 2017 Jun 17.  Abstract  
submitted by kickingbird at Jun, 27, 2017 from Antiviral Res 2017 Jun 17 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28633988/)
The sporadic outbreaks of highly pathogenic H5N1 avian influenza virus have raised public health concerns. Monoclonal antibodies (MAbs) against hemagglutinin (HA) have been increasingly used successfully ...

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