Nicol MQ, et al. Lack of IFNγ signaling attenuates spread of influenza A virus in vivo and leads to reduced pathogenesis. Virology. 2018 Oct 31;526:155-164. Abstract
submitted by kickingbird at Nov, 7, 2018 from Virology. 2018 Oct 31;526:155-164 (via https://www.ncbi.nlm.nih.gov/pubmed/30390564)
IFNγ is a key regulator of inflammatory responses but its role in influenza A virus (IAV) pathogenesis is unclear. Our studies show that infection of mice lacking the IFNγ receptor (IFNγR-/-) at a dose ... Matos AR, et al. Human CCR5Δ32 (rs333) polymorphism has no influence on severity and mortality of influenza A(H1N1)pdm09 infection in Brazilian patients from the post pandemic period. Infect Genet Evol. 2018 Oct 31;67:55-59. Abstract
submitted by kickingbird at Nov, 7, 2018 from Infect Genet Evol. 2018 Oct 31;67:55-59 (via https://www.ncbi.nlm.nih.gov/pubmed/30389547)
BACKGROUND: Influenza is an acute and highly contagious viral respiratory infection that causes significant morbidity and mortality. The identification of host genetic factors associated with susceptibility ... Robertson CA, et al. Safety and Immunogenicity of a Full-Dose Split-Virion Inactivated Quadrivalent Influenza Vaccine in Healthy Children 6 to 35 Months of Age: A Randomized Controlled Clinical Trial. Pediatr Infect Dis J. 2018 Nov 2. Abstract
submitted by kickingbird at Nov, 7, 2018 from Pediatr Infect Dis J. 2018 Nov 2 (via https://www.ncbi.nlm.nih.gov/pubmed/30395011)
BACKGROUND: For children aged METHODS: In this phase IV, randomized, observer-blinded, multi-center study, healthy children aged 6 to 35 months were randomized 1:1 to be vaccinated with a half or full ... Poirot E, et al. Detection of Avian Influenza A(H7N2) Virus Infection Among Animal Shelter Workers Using a Novel Serological Approach-New York City, 2016-2017. J Infect Dis. 2018 Nov 5.. Abstract
submitted by kickingbird at Nov, 7, 2018 from J Infect Dis. 2018 Nov 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30395249)
Background: In 2016, an influenza A(H7N2) virus outbreak occurred in cats in New York City's municipal animal shelters. One human infection was initially detected.Methods: We conducted a serological survey ... Hong ZY, et al. Equipping inner central components of influenza A virus with quantum dots. Anal Chem. 2018 Nov 5.. Abstract
submitted by kickingbird at Nov, 7, 2018 from Anal Chem. 2018 Nov 5. (via https://pubs.acs.org/doi/10.1021/acs.analchem.8b03995)
Influenza A virus (IAV), a risk to public health, is enveloped and contains viral ribonucleoprotein (vRNP) complexes, where vRNP complexes are centrality to every aspect of IAV life cycle. Labeling both ... Shah P, Zaveri JS, Haddock LJ.. Acute Macular Neuroretinopathy Following the Administration of an Influenza Vaccination. Ophthalmic Surg Lasers Imaging Retina. Abstract
submitted by kickingbird at Nov, 7, 2018 from Ophthalmic Surg Lasers Imaging Retina (via https://www.ncbi.nlm.nih.gov/pubmed/30395681)
This manuscript reports a rare association of the development of acute macular neuroretinopathy (AMN) after administration of an influenza vaccination. A 42-year-old white female presented with a 2-week ... Mohseni SS, et al. Identification of novel inhibitor against endonuclease subunit of Influenza pH1N1 polymerase: A combined molecular docking, molecular dynamics, MMPBSA, QMMM and ADME studies to combat influenza A viru. Comput Biol Chem. 2018 Aug 23;77:279-290. Abstract
submitted by kickingbird at Nov, 7, 2018 from Comput Biol Chem. 2018 Aug 23;77:279-290 (via https://www.ncbi.nlm.nih.gov/pubmed/30396155)
The influenza H1N1 virus is the causative agent of the flu pandemic in the world. Due to the shortage of effective means of control, it is remained the serious threats to public and avian health. To battle ... Song JY, et al. Immunogenicity and safety of an egg-based inactivated quadrivalent influenza vaccine (GC3110A) versus two inactivated trivalent influenza vaccines with alternate B strains: A phase Ⅲ randomized clinic. Hum Vaccin Immunother. 2018 Nov 5. Abstract
submitted by kickingbird at Nov, 7, 2018 from Hum Vaccin Immunother. 2018 Nov 5 (via https://www.ncbi.nlm.nih.gov/pubmed/30396317)
Two antigenically distinct influenza B lineage viruses (Yamagata/Victoria) have been co-circulating globally since the mid-1980s. The quadrivalent influenza vaccine (QIV) may provide better protection ... Kikuchi T, Watanabe A. Baloxavir heralds a new era in influenza virus biology. Respir Investig. 2018 Nov 2. Abstract
submitted by kickingbird at Nov, 7, 2018 from Respir Investig. 2018 Nov 2 (via https://www.ncbi.nlm.nih.gov/pubmed/30396860)
Baloxavir marboxil is an orally available prodrug of baloxavir acid. Japan was the first country to approve baloxavir marboxil as a treatment for influenza. The antiviral mechanism of action of baloxavir ... Il Kim J, et al. Distinct molecular evolution of influenza H3N2 strains in the 2016/17 season and its implications for vaccine effectiveness. Mol Phylogenet Evol. 2018 Nov 3.. Abstract
submitted by kickingbird at Nov, 7, 2018 from Mol Phylogenet Evol. 2018 Nov 3. (via https://www.ncbi.nlm.nih.gov/pubmed/30399431)
Influenza virus is a respiratory pathogen that causes seasonal epidemics by resulting in a considerable number of influenza-like illness (ILI) patients. During the 2016/17 season, ILI rates increased unusually ... Alkie TN, Yitbarek A, Taha-Abdelaziz K, et al. Characterization of immunogenicity of avian influenza antigens encapsulated in PLGA nanoparticles following mucosal and subcutaneous delivery in chickens. PLoS One. 2018 Nov 1;13(11):e0206324. Abstract
submitted by kickingbird at Nov, 6, 2018 from PLoS One. 2018 Nov 1;13(11):e0206324 (via https://www.ncbi.nlm.nih.gov/pubmed/30383798)
Mucosal vaccine delivery systems have paramount importance for the induction of mucosal antibody responses. Two studies were conducted to evaluate immunogenicity of inactivated AIV antigens encapsulated ... KyungHyun Lee, et al. Highly Pathogenic Avian Influenza A(H5N6) in Domestic Cats, South Korea. Emerg Infect Dis. 2018 Dec. Abstract
submitted by kickingbird at Nov, 3, 2018 from Emerg Infect Dis. 2018 Dec (via https://wwwnc.cdc.gov/eid/article/24/12/18-0290_article)
In December 2016, highly pathogenic avian influenza (HPAI) infection with systemic pathological lesions was found in cats in South Korea. Genetic analyses indicated that the feline isolates were similar ... Sun J, Brooke CB. Influenza A Virus Superinfection Potential Is Regulated by Viral Genomic Heterogeneity. MBio. 2018 Oct 30;9(5). Abstract
submitted by kickingbird at Nov, 3, 2018 from MBio. 2018 Oct 30;9(5) (via https://www.ncbi.nlm.nih.gov/pubmed/30377278)
Defining the specific factors that govern the evolution and transmission of influenza A virus (IAV) populations is of critical importance for designing more-effective prediction and control strategies. ... Goldhill DH, et al. Determining the Mutation Bias of Favipiravir in Influenza Using Next-generation Sequencing. J Virol. 2018 Oct 31. Abstract
submitted by kickingbird at Nov, 3, 2018 from J Virol. 2018 Oct 31 (via https://www.ncbi.nlm.nih.gov/pubmed/30381482)
avipiravir is a broad-spectrum antiviral drug that may be used to treat influenza. Previous research has identified that favipiravir likely acts as a mutagen but the precise mutation bias that favipiravir ... Prachanronarong KL, et al. Mutations in influenza A virus neuraminidase and hemagglutinin confer resistance against a broadly neutralizing hemagglutinin stem antibody. J Virol. 2018 Oct 31. Abstract
submitted by kickingbird at Nov, 3, 2018 from J Virol. 2018 Oct 31 (via https://www.ncbi.nlm.nih.gov/pubmed/30381484)
Influenza A virus (IAV), a major cause of human morbidity and mortality, continuously evolves in response to selective pressures. Stem-directed, broadly neutralizing antibodies (sBnAbs) targeting influenza ... Meliopoulos V, et al. Absence of β6 integrin reduces influenza disease severity in highly susceptible obese mice. J Virol. 2018 Oct 31.. Abstract
submitted by kickingbird at Nov, 3, 2018 from J Virol. 2018 Oct 31. (via https://www.ncbi.nlm.nih.gov/pubmed/30381485)
Obese individuals are considered a high-risk group for developing severe influenza virus infection. While the exact mechanisms for increased disease severity remain under investigation, obese mouse models ... Sun W, et al. Antibody responses towards the major antigenic sites of influenza B virus hemagglutinin in mice, ferrets and humans. J Virol. 2018 Oct 31. Abstract
submitted by kickingbird at Nov, 3, 2018 from J Virol. 2018 Oct 31 (via https://www.ncbi.nlm.nih.gov/pubmed/30381487)
The influenza B virus hemagglutinin contains four major antigenic sites (the 120 loop, the 150 loop, the 160 loop and the 190 helix) within the head domain. These immunodominant antigenic sites are the ... Wang SC, Liao HY, Zhang JY, Cheng TR, Wong CH. Development of a universal influenza vaccine using hemagglutinin stem protein produced from Pichia pastoris. Virology. 2018 Oct 26;526:125-137. Abstract
submitted by kickingbird at Nov, 3, 2018 from Virology. 2018 Oct 26;526:125-137 (via https://www.ncbi.nlm.nih.gov/pubmed/30388628)
The development of a universal influenza vaccine has become a major effort to combat the high mutation rate of influenza. To explore the use of the highly conserved stem region of hemagglutinin (HA) as ... Bhardwaj J, Sharma A, Jang J. Vertical flow-based paper immunosensor for rapid electrochemical and colorimetric detection of influenza virus using a different pore size sample pad. Biosens Bioelectron. 2018 Oct 19;126:36-43. Abstract
submitted by kickingbird at Nov, 3, 2018 from Biosens Bioelectron. 2018 Oct 19;126:36-43 (via https://www.ncbi.nlm.nih.gov/pubmed/30388552)
We present a novel vertical flow-based paper immunosensor for the rapid and sensitive electrochemical and colorimetric detection of influenza H1N1 viruses using a different pore size (DP) sample pad. The ... Hussain S, et al. Mutation of influenza A virus PA-X decreases pathogenicity in chicken embryos and can increase the yield of reassortant candidate vaccine viruses. J Virol. 2018 Oct 31.. Abstract
submitted by kickingbird at Nov, 3, 2018 from J Virol. 2018 Oct 31. (via https://www.ncbi.nlm.nih.gov/pubmed/30381488)
The PA-X protein of influenza A virus has roles in host cell shut-off and viral pathogenesis. While most strains are predicted to encode PA-X, strain-dependent variations in activity have been noted. We ... 7558 items, 20/Page, Page[183/378][|<<] [|<] [181] [182] [183] [184] [185] [186] [187] [188] [189] [190] [>|] [>>|] |
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