Desirò D, H?lzer M, Ibrahim B, Marz M. SilentMutations (SIM): a tool for analyzing long-range RNA-RNA interactions in viral genomes and structured RNAs. Virus Res. 2018 Nov 12.. Abstract
submitted by kickingbird at Nov, 17, 2018 from Virus Res. 2018 Nov 12. (via https://www.ncbi.nlm.nih.gov/pubmed/30439394)
A single nucleotide change in the coding region can alter the amino acid sequence of a protein. In consequence, natural or artificial sequence changes in viral RNAs may have various effects not only on ... Barbezange C, et al. Seasonal Genetic Drift of Human Influenza A Virus Quasispecies Revealed by Deep Sequencing. Front Microbiol. 2018 Oct 31;9:2596.. Abstract
submitted by kickingbird at Nov, 17, 2018 from Front Microbiol. 2018 Oct 31;9:2596. (via https://www.ncbi.nlm.nih.gov/pubmed/30429836)
After a pandemic wave in 2009 following their introduction in the human population, the H1N1pdm09 viruses replaced the previously circulating, pre-pandemic H1N1 virus and, along with H3N2 viruses, are ... Allen JD, et al. Elicitation of protective antibodies against 20 years of future H3N2 co-ciruculating influenza virus variants in ferrets preimmune to historical H3N2 influenza viruses. J Virol. 2018 Nov 14.. Abstract
submitted by kickingbird at Nov, 17, 2018 from J Virol. 2018 Nov 14. (via https://www.ncbi.nlm.nih.gov/pubmed/30429350)
The vast majority of people already have pre-existing immune responses to influenza viruses from one or more subtypes. However, almost all preclinical studies evaluate new influenza vaccine candidates ... Beyleveld G, et al. Nucleolar Relocalization of RBM14 by Influenza A Virus NS1 Protein. mSphere. 2018 Nov 14;3(6).. Abstract
submitted by kickingbird at Nov, 17, 2018 from mSphere. 2018 Nov 14;3(6). (via https://www.ncbi.nlm.nih.gov/pubmed/30429226)
Viruses utilize a number of host factors in order to carry out their replication cycles. Influenza A virus (IAV) and human respiratory syncytial virus (RSV) both infect the tissues of the respiratory tract, ... Ye F, et al. Analysis of influenza B virus lineages and the HA1 domain of its hemagglutinin gene in Guangzhou, southern China, during 2016. Virol J. 2018 Nov 14;15(1):175. Abstract
submitted by kickingbird at Nov, 17, 2018 from Virol J. 2018 Nov 14;15(1):175 (via https://www.ncbi.nlm.nih.gov/pubmed/30428893)
BACKGROUND: Few studies have analyzed influenza B virus lineages based on hemagglutinin A (HA) gene sequences in southern China. The present study analyzed the HA gene and the lineages of influenza B virus ... Souty C, et al. Influenza epidemics observed in primary care from 1984 to 2017 in France: a decrease of epidemic size over time. Influenza Other Respir Viruses. 2018 Nov 14.. Abstract
submitted by kickingbird at Nov, 17, 2018 from Influenza Other Respir Viruses. 2018 Nov 14. (via https://www.ncbi.nlm.nih.gov/pubmed/30428158)
BACKGROUND: Epidemiological analysis of past influenza epidemics remains essential to understand the evolution of the disease and optimize control and prevention strategies. Here, we aimed to use data ... Hilton SK, Bloom JD. Modeling site-specific amino-acid preferences deepens phylogenetic estimates of viral sequence divergence. Virus Evol. 2018 Nov 6;4(2):vey033. Abstract
submitted by kickingbird at Nov, 17, 2018 from Virus Evol. 2018 Nov 6;4(2):vey033 (via https://www.ncbi.nlm.nih.gov/pubmed/30425841)
Molecular phylogenetics is often used to estimate the time since the divergence of modern gene sequences. For highly diverged sequences, such phylogenetic techniques sometimes estimate surprisingly recent ... Song L, Xiong D, Kang X, Jiao Y, et al.. The optimized fusion protein HA1-2-FliC△D2D3 promotes mixed Th1/Th2 immune responses to influenza H7N9 with low induction of systemic proinflammatory cytokines in mice. Antiviral Res 2018 Oct 30. Abstract
submitted by kickingbird at Nov, 15, 2018 from Antiviral Res 2018 Oct 30 (via https://www.ncbi.nlm.nih.gov/pubmed/30389471)
H7N9 influenza virus has an unusually high fatality rate of approximately 40%, and a safe and effective vaccine against this subtype is urgently needed. Flagellin, a Toll-like receptor (TLR) 5 agonist, ... Jia X, et al. Delayed oseltamivir plus sirolimus treatment attenuates H1N1 virus-induced severe lung injury correlated with repressed NLRP3 inflammasome activation and inflammatory cell infiltration. PLoS Pathog. 2018 Nov 13;14(11):. Abstract
submitted by kickingbird at Nov, 15, 2018 from PLoS Pathog. 2018 Nov 13;14(11): (via https://www.ncbi.nlm.nih.gov/pubmed/30422993)
Severe influenza A virus infection causes high mortality and morbidity worldwide due to delayed antiviral treatment and inducing overwhelming immune responses, which contribute to immunopathological lung ... Butler AM, et al. Assessing Residual Bias in Estimating Influenza Vaccine Effectiveness: Comparison of High-dose Versus Standard-dose Vaccines. Med Care. 2018 Nov 12.. Abstract
submitted by kickingbird at Nov, 15, 2018 from Med Care. 2018 Nov 12. (via https://www.ncbi.nlm.nih.gov/pubmed/30422840)
BACKGROUND: Estimating influenza vaccine effectiveness using an unvaccinated comparison group may result in biased effect estimates.OBJECTIVES: To explore the reduction of confounding bias in an active ... Chen T, Xiao M, Yang J, Chen YK, Bai T, et al. Association between rs12252 and influenza susceptibility and severity: an updated meta-analysis. Epidemiol Infect. 2018 Nov 13:1-9. Abstract
submitted by kickingbird at Nov, 15, 2018 from Epidemiol Infect. 2018 Nov 13:1-9 (via https://www.ncbi.nlm.nih.gov/pubmed/30421689)
In several lately published studies, the association between single-nucleotide polymorphism (SNP, rs12252) of IFITM3 and the risk of influenza is inconsistent. To further understand the association between ... Littauer EQ, Skountzou I. Hormonal Regulation of Physiology, Innate Immunity and Antibody Response to H1N1 Influenza Virus Infection During Pregnancy. Front Immunol. 2018 Oct 29;9:2455. Abstract
submitted by kickingbird at Nov, 15, 2018 from Front Immunol. 2018 Oct 29;9:2455 (via https://www.ncbi.nlm.nih.gov/pubmed/30420854)
In 2009, the H1N1 swine flu pandemic highlighted the vulnerability of pregnant women to influenza viral infection. Pregnant women infected with influenza A virus were at increased risk of hospitalization ... Lee KM, et al. Coinfection With Influenza A Virus and Klebsiella oxytoca: An Underrecognized Impact on Host Resistance and Tolerance to Pulmonary Infections. Front Immunol. 2018 Oct 29;9:2377. Abstract
submitted by kickingbird at Nov, 15, 2018 from Front Immunol. 2018 Oct 29;9:2377 (via https://www.ncbi.nlm.nih.gov/pubmed/30420852)
Pneumonia is a world health problem and a leading cause of death, particularly affecting children and the elderly (1, 2). Bacterial pneumonia following infection with influenza A virus (IAV) is associated ... Shang M, et al. Influenza vaccine effectiveness among patients with high-risk medical conditions in the United States, 2012~2016. Vaccine. 2018 Nov 9. Abstract
submitted by kickingbird at Nov, 15, 2018 from Vaccine. 2018 Nov 9 (via https://www.ncbi.nlm.nih.gov/pubmed/30420119)
BACKGROUND: Annual influenza vaccination has been recommended for persons with high-risk conditions since the 1960s. However, few estimates of influenza vaccine effectiveness (VE) for persons with high-risk ... Kang HR, Lee EK, Kim WJ, Shin JY. Risk of neuropsychiatric adverse events associated with the use of oseltamivir: a nationwide population-based case-crossover study. J Antimicrob Chemother. 2018 Nov 12. Abstract
submitted by kickingbird at Nov, 15, 2018 from J Antimicrob Chemother. 2018 Nov 12 (via https://www.ncbi.nlm.nih.gov/pubmed/30418537)
Background: Although the potential risk of neuropsychiatric adverse events (NPAEs) upon administration of oseltamivir has been raised in case reports, the association between the use of oseltamivir and ... Wilcox CR, et al. Determinants of Influenza and Pertussis Vaccination Uptake in Pregnancy: A Multi-Centre Questionnaire Study of Pregnant Women and Healthcare Professionals. Pediatr Infect Dis J. 2018 Nov 9. Abstract
submitted by kickingbird at Nov, 15, 2018 from Pediatr Infect Dis J. 2018 Nov 9 (via https://www.ncbi.nlm.nih.gov/pubmed/30418358)
INTRODUCTION: Uptake rates of antenatal vaccination remain suboptimal. Our aims were to determine: (1) the acceptability of routine vaccination among pregnant women, (2) the confidence of maternity healthcare ... Munoz FM, et al. Safety and immunogenicity of seasonal trivalent inactivated influenza vaccines in pregnant women. Vaccine. 2018 Nov 8. Abstract
submitted by kickingbird at Nov, 15, 2018 from Vaccine. 2018 Nov 8 (via https://www.ncbi.nlm.nih.gov/pubmed/30416018)
BACKGROUND: In the United States, seasonal inactivated influenza vaccine (IIV) is recommended for pregnant women; however, in early 2009, immunization rates were low, partly due to limited prospective ... Wohlgemuth N, Lane AP, Pekosz A. Influenza A Virus M2 Protein Apical Targeting Is Required for Efficient Virus Replication. J Virol. 2018 Oct 29;92(22).. Abstract
submitted by kickingbird at Nov, 13, 2018 from J Virol. 2018 Oct 29;92(22). (via https://www.ncbi.nlm.nih.gov/pubmed/30158290)
The influenza A virus (IAV) M2 protein is a multifunctional protein with critical roles in virion entry, assembly, and budding. M2 is targeted to the apical plasma membrane of polarized epithelial cells, ... Ather JL, et al. Serum Amyloid A3 is required for normal lung development and survival following influenza infection. Sci Rep. 2018 Nov 8;8(1):16571.. Abstract
submitted by kickingbird at Nov, 13, 2018 from Sci Rep. 2018 Nov 8;8(1):16571. (via https://www.ncbi.nlm.nih.gov/pubmed/30410021)
Serum amyloid A (SAA) proteins are a family of acute phase apolipoproteins implicated to directly modulate innate and adaptive immune responses. However, new studies comparing endogenous SAAs and recombinant ... Mine J, et al. Genetic and antigenic dynamics of influenza A viruses of swine on pig farms in Thailand. Arch Virol. 2018 Nov 10.. Abstract
submitted by kickingbird at Nov, 13, 2018 from Arch Virol. 2018 Nov 10. (via https://www.ncbi.nlm.nih.gov/pubmed/30415389)
Surveillance studies of influenza A virus of swine (IAV-S) have accumulated information regarding IAVs-S circulating in Thailand, but how IAVs-S evolve within a farm remains unclear. In the present study, ... 7530 items, 20/Page, Page[180/377][|<<] [|<] [171] [172] [173] [174] [175] [176] [177] [178] [179] [180] [>|] [>>|] |
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