Andreev, K., Jones, J.C., Kandeil, A. et al. Baloxavir outperforms oseltamivir, favipiravir, and amantadine in treating lethal influenza A(H5N1) HA clade 2.3.4.4b infection in mice. Nat Commun (2026). Abstract
submitted by kickingbird at 13 days ago from Nat Commun (2026) (via https://www.nature.com/articles/s41467-026-69721-5)
Intercontinental spread of highly pathogenic avian influenza A(H5N1) viruses poses significant pandemic risks and necessitates strong protective countermeasures. We evaluated the therapeutic efficacy of ... Hui Yang, etc.,al. Dual roles of USP39 in stabilizing PB2 and orchestrating ribonucleoprotein assembly drive H5 influenza virus replication and pathogenicity. Cell Reports. Abstract
submitted by kickingbird at 13 days ago from Cell Reports (via https://www.sciencedirect.com/science/article/pii/S221112472)
Host cells combat avian influenza virus (AIV) infection by targeting viral polymerase PB2 for degradation, yet how the virus counteracts this remains elusive. In this study, we analyze the host proteins ... Kaituo Liu, etc.,al. Zoonotic Threat of Novel H6N2 Avian Influenza Virus with Internal Genes Exclusively Derived from H9N2, China, 2025. Journal of Infection. Abstract
submitted by kickingbird at 13 days ago from Journal of Infection (via https://www.sciencedirect.com/science/article/pii/S016344532)
A recent article by Song in the Journal of Infection systematically analyzed the global spatiotemporal distribution and transmission routes of H6 subtype avian influenza viruses (AIVs), revealing their ... Li F, Song K, Ren X. Prognostic factors in H7N9 avian influenza: a systematic review based on case reports. BMC Infect Dis. 2026 Feb 18. Abstract
submitted by kickingbird at 13 days ago from BMC Infect Dis. 2026 Feb 18 (via https://link.springer.com/article/10.1186/s12879-026-12908-4)
ObjectiveThe H7N9 avian influenza virus, identified in China in 2013, has posed a significant threat to public health due to its high mortality rate. This systematic review aims to evaluate the clinical ... Nakano T, Esaki M, Inoue A, Koike F, Okuya K, etc. Impact of an amino acid deletion detected in the hemagglutinin (HA) antigenic site of swine influenza A virus field strains on HA antigenicity. J Virol. 2026 Feb 19:e0182025. Abstract
submitted by kickingbird at 13 days ago from J Virol. 2026 Feb 19:e0182025 (via https://journals.asm.org/doi/10.1128/jvi.01820-25)
Swine influenza A virus (swIAV) is an important pathogen with regard to both the swine industry and public health. The pandemic A(H1N1) 2009 outbreak was caused by the swine-origin pandemic A(H1N1) 2009 ... Shila, R. A., I. Hossain, R. Parvin, E. H. Chowdhu. Chicken Origin Tribasic H9N2 Avian Influenza Virus Induces Potent Early Antiviral Response With Low Pathogenicity in Japanese Quails. Veterinary Medicine and Science 12, no. 2: e70834. Abstract
submitted by kickingbird at 13 days ago from Veterinary Medicine and Science 12, no. 2: e70834 (via https://onlinelibrary.wiley.com/doi/10.1002/vms3.70834)
BackgroundLow-pathogenic avian influenza (LPAI) virus H9N2 has been endemic in Bangladesh since 2006. While the molecular epidemiology and pathogenicity of circulating tribasic H9N2 viruses are well-documented ... R?mo, Grim, ?kesson, Caroline Piercey, Reiertsen,. Highly Pathogenic Avian Influenza A (H5N1) Caused Mass Death Among Black-Legged Kittiwakes (Rissa tridactyla) in Norway, 2023. Transboundary and Emerging Diseases, 2026, 2963364. Abstract
submitted by kickingbird at 13 days ago from Transboundary and Emerging Diseases, 2026, 2963364 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/2963364)
In 2023, highly pathogenic avian influenza (HPAI) heavily affected gulls in Europe. In July, a mass mortality event was reported in the black-legged kittiwake (Rissa tridactyla) breeding colony at Ekker?y ... Ali, M.A., Ataei Kachouei, M., Jacobs, L. et al. Multimodal sensing technologies for HPAI biosurveillance in poultry production systems. npj Biosensing 3, 11 (2026). Abstract
submitted by kickingbird at 13 days ago from npj Biosensing 3, 11 (2026) (via https://www.nature.com/articles/s44328-025-00075-6)
Highly pathogenic avian influenza (HPAI), with a current focus on the emergent H5N1 clade 2.3.4.4b, remains a substantial and evolving threat to animal health, food security, and zoonotic safety. Since ... Silje Granstad, etc.,al. [preprint]Multiple Introductions of Highly Pathogenic Avian Influenza Viruses into the High Arctic: Svalbard and Jan Mayen, 2022~2025. https://doi.org/10.64898/2026.02.17.706283. Abstract
submitted by kickingbird at 13 days ago from https://doi.org/10.64898/2026.02.17.706283 (via https://www.biorxiv.org/content/10.64898/2026.02.17.706283v1)
Between 2022 and 2025, highly pathogenic avian influenza viruses (HPAIVs) of clade 2.3.4.4b, including four distinct H5 Eurasian (EA) genotypes, were detected in wild birds and mammals in the Svalbard ... He W, Li X, Liang X, Liu Z, Zeng Z, Yang Z, Hon C. FaXNet: a frequency-adaptive, explainable, and uncertainty-aware network for influenza forecasting. Front Public Health. 2026 Feb 2;14:1746529. Abstract
submitted by kickingbird at 14 days ago from Front Public Health. 2026 Feb 2;14:1746529 (via https://www.frontiersin.org/journals/public-health/articles/)
Background: Accurate and interpretable influenza forecasting is critical for public health preparedness, yet many models struggle to capture multi-scale temporal dynamics and to provide reliable uncertainty ... Daly RE, Feng CY, Hesser CR, Myasnikov I, Gaglia M. N-terminal acetylation controls multiple functional aspects of the influenza A virus ribonuclease PA-X. J Virol 100:e01999-25. Abstract
submitted by kickingbird at 14 days ago from J Virol 100:e01999-25 (via https://journals.asm.org/doi/10.1128/jvi.01999-25)
To counteract host antiviral responses, influenza A virus triggers a global reduction of cellular gene expression, a process termed “host shutoff.” A key effector of influenza A virus host shutoff is the ... Naveed A, Yu J, Sreenivasan CC, Huang C, Zhao M, U. Bovine influenza D virus replicates in the gastrointestinal tract but has limited ability for fecal-oral transmission in experimental infected guinea pigs. ASM Anim Microbiol 0:e00014-25. Abstract
submitted by kickingbird at 14 days ago from ASM Anim Microbiol 0:e00014-25 (via https://journals.asm.org/doi/10.1128/asmam.00014-25)
Respiratory influenza D virus (IDV), first identified in 2011, has since been detected globally in bovine populations. Considering the high thermal and acidic stability of IDV, coupled with the observations ... Kobayashi D, Hiono T, Isoda N, Sakoda Y. Neuraminidase of influenza A viruses induces global desialylation of host cells via its intracellular function. Microbiol Spectr. 2026 Feb 18:e0332825. Abstract
submitted by kickingbird at 14 days ago from Microbiol Spectr. 2026 Feb 18:e0332825 (via https://journals.asm.org/doi/10.1128/spectrum.03328-25)
The neuraminidase protein (NA) of influenza A viruses (IAVs) plays a role in the release of viruses from infected cells. NA on viral particles hydrolyzes sialylated glycans on the cell surface for viral ... Jeremy C. Jones et al. Baloxavir alleviates severe disease and viremia in ferrets infected with avian- or bovine-origin influenza A(H5N1) virus. Sci. Transl. Med.18,eadt3889(2026). Abstract
submitted by kickingbird at 14 days ago from Sci. Transl. Med.18,eadt3889(2026) (via https://www.science.org/doi/10.1126/scitranslmed.adt3889)
Highly pathogenic avian influenza A(H5N1) hemagglutinin (HA) clade 2.3.4.4b viruses are now circulating in wild birds and agricultural species (poultry and dairy cows), resulting in multiple human infections. ... Wang, X., Zhao, Z., Shi, M., Xu, S., Zhou, X.,. Genetically engineered M13 phage-mediated H9N2 DNA vaccine with enhanced mucosal and systemic immune responses in mice. Drug Delivery, 33(1). Abstract
submitted by kickingbird at 15 days ago from Drug Delivery, 33(1) (via https://www.tandfonline.com/doi/full/10.1080/10717544.2026.2)
Vaccine adjuvants and delivery systems have long been used in DNA vaccines to enhance immunogenicity. In this study, we developed a DNA vaccine delivery platform by combining N-2-hydroxypropyl trimethyl ... Samantha Zoomer, etc.,al. Zoonotic Influenza Preparedness: Dutch Medical Labs Efficiently Detect Animal Influenza A Viruses - External Quality Assessment, 2023. Journal of Clinical Virology. Abstract
submitted by kickingbird at 15 days ago from Journal of Clinical Virology (via https://www.sciencedirect.com/science/article/pii/S138665322)
BackgroundSince 2022, highly pathogenic H5N1 influenza A virus clade 2.3.4.4b has caused global outbreaks among wild birds and poultry, with increasing mammalian and sporadic human infections. This elevates ... Michelle Wille, etc.,al. [preprint]Skuas as sentinels of high pathogenicity avian influenza H5N1 on the Antarctic Peninsula in the 2024/2025 austral summer. https://doi.org/10.64898/2026.02.15.706047. Abstract
submitted by kickingbird at 15 days ago from https://doi.org/10.64898/2026.02.15.706047 (via https://www.biorxiv.org/content/10.64898/2026.02.15.706047v1)
Despite Antarcticas geographic isolation, the first incursion of high pathogenicity avian influenza (HPAI) H5N1 was detected in the 2023/24 austral summer. Surveillance for HPAI H5N1 in Antarctica remains ... Li Y, Zhang X, Zhou X, Zhu X, Tan L, Pan Z, Huang. Cross-Reactive Antibody Responses to Emerging Bovine H5N1 Clade 2.3.4.4b Following Seasonal Influenza Vaccination: Implications for Pandemic Preparedness. Viral Immunol. 2026 Feb 16:8828245261424908. Abstract
submitted by kickingbird at Feb, 17, 2026 from Viral Immunol. 2026 Feb 16:8828245261424908 (via https://journals.sagepub.com/doi/10.1177/08828245261424908)
Background: The emergence of highly pathogenic avian influenza A (H5N1) clade 2.3.4.4b in dairy cattle and human cases raises urgent pandemic concerns. A critical question is whether seasonal influenza ... Fang C, Sun X, Feng Y, Song H, Wang S. PB1 mutations as key drivers of influenza A virus evolution. Front Microbiol. 2026 Jan 29;17:1768665. Abstract
submitted by kickingbird at Feb, 17, 2026 from Front Microbiol. 2026 Jan 29;17:1768665 (via https://www.frontiersin.org/journals/microbiology/articles/1)
Influenza A virus (IAV) is a zoonotic pathogen with a broad host range, posing an ongoing threat to global public health. As the core subunit of the IAV polymerase, polymerase basic protein 1 (PB1) is ... Cui J, Foo SSW, Kong WT, Lin C, Ampomah PB, Zharko. Irf7 Deficiency Confers Protection Against Influenza Infection, Independent of irf3. Int J Biol Sci. 2026 Jan 22;22(4):1974-1996. Abstract
submitted by kickingbird at Feb, 17, 2026 from Int J Biol Sci. 2026 Jan 22;22(4):1974-1996 (via https://www.ijbs.com/v22p1974.htm)
Interferon regulatory factors irf3 and irf7 are pivotal for antiviral immunity, yet their cell-type-specific contributions, particularly within macrophage and dendritic cell (DC) lineages, have not been ... 9869 items, 20/Page, Page[4/494][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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