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2026-5-30 21:24:03
Article

Jia L, Qiu R, et al. Evaluation of Safety and Immunogenicity of High-Dose Quadrivalent Seasonal Influenza Split Vaccine: A Preclinical Study. Vaccines. 2026; 14(5):446.  Abstract  
submitted by kickingbird at 13 days ago from Vaccines. 2026; 14(5):446 (via https://www.mdpi.com/2076-393X/14/5/446)
Objectives: Seasonal influenza leads to substantial global morbidity and mortality, especially in adults aged 65 years and older, who present poor immune responses to standard-dose influenza vaccines. ...

Jennifer F Provencher, Andre Morrill, Holly L Henn. Interannual differences in common eider duck exposure to avian influenza viruses at an Arctic colony. Conservation Physiology, Volume 14.  Abstract  
submitted by kickingbird at 13 days ago from Conservation Physiology, Volume 14 (via https://academic.oup.com/conphys/article/14/1/coag033/867582)
Avian Influenza viruses (AIVs) regularly circulate among migratory birds, but starting in late 2021 an incursion of highly pathogenic AIV (HPAIV; H5N1 clade 2.3.4.4b) was detected widely in North American ...

Qu, R., Yang, L., Li, S. et al. Disentangling the drivers and host-mediated global spread of H7 influenza A virus. Nat Commun (2026).  Abstract  
submitted by kickingbird at 13 days ago from Nat Commun (2026) (via https://link.springer.com/article/10.1038/s41467-026-72718-9)
Avian influenza H7 viruses pose a significant zoonotic and pandemic threat, yet their evolutionary dynamics, spatial transmission patterns, and host-specific roles remain underexplored. This study integrates ...

Hsiang Hong, etc.,al. [preprint]A Panel of Human Monoclonal Antibodies for Tracking the Antigenic Evolution of Influenza H5N1 Clade 2.3.4.4b. https://doi.org/10.64898/2026.05.14.725215.  Abstract  
submitted by kickingbird at 14 days ago from https://doi.org/10.64898/2026.05.14.725215 (via https://www.biorxiv.org/content/10.64898/2026.05.14.725215v1)
The ongoing panzootic of clade 2.3.4.4b H5N1 influenza has resulted in widespread infection of birds, mammals, and livestock, underscoring the need for tools to interpret its real-time evolution. Here, ...

Johanna A. Harvey, etc.,al. Feathers and flu: identifying data gaps in avian influenza host dynamics to prioritize wildlife conservation. Wildlife Monographs.  Abstract  
submitted by kickingbird at 14 days ago from Wildlife Monographs (via https://wildlife.onlinelibrary.wiley.com/doi/10.1002/wmon.70)
Highly pathogenic avian influenza viruses (HPAIV) have had disastrous, worldwide effects on wild birds and domestic poultry since the emergence of the A/goose/Guangdong/1/1996 (Gs/GD/96) lineage. The currently ...

Marandino A, Tomás G, Panzera Y, Uriarte V, Russi. Reassortant High Pathogenicity Avian Influenza A(H5N1) Viruses During the Reemergence in Uruguay Suggest Increasing Genetic Diversity in South America. Viruses. 2026; 18(5):558.  Abstract  
submitted by kickingbird at 14 days ago from Viruses. 2026; 18(5):558 (via https://www.mdpi.com/1999-4915/18/5/558)
Highly pathogenic avian influenza (HPAI) H5N1 viruses of the goose/Guangdong (Gs/GD) lineage have driven a global panzootic since 2020, with clade 2.3.4.4b establishing sustained transmission in wild birds. ...

Zhuang, Y., Chen, L., Qin, C. et al. A nanobody-based proteolysis-targeting chimera offers broad-spectrum protection against diverse influenza virus infections. Sig Transduct Target Ther 11, 182 (2026).  Abstract  
submitted by kickingbird at 15 days ago from Sig Transduct Target Ther 11, 182 (2026) (via https://link.springer.com/article/10.1038/s41392-026-02666-9)
Influenza A viruses continue to pose a major threat to global public health. In addition to H1N1 and H3N2 subtypes causing seasonal epidemics that result in an estimated 3–5 million severe cases and 290,000–650,000 ...

Sun, X., Lisboa, C., Carney, P.J. et al. Hemagglutinin E190D substitution in clade 2.3.4.4b A(H5N1) influenza virus reduces receptor binding and viral fitness. npj Viruses (2026).  Abstract  
submitted by kickingbird at 15 days ago from npj Viruses (2026) (via https://www.nature.com/articles/s44298-026-00197-2)
The detection of a clade 2.3.4.4b influenza A(H5N1) virus bearing an HA-E190D substitution in an infected human raises concern about mammalian adaptation. We evaluated the impact of the naturally occurring ...

Oremush R, Aubry P, Parmley EJ, Poljak Z, Greer A. Determining the Environmental and Ecological Factors Associated With Poultry Farm Spillover of Highly Pathogenic Avian Influenza (H5N1) in British Columbia, Canada. Zoonoses Public Health. 2026 May 15.  Abstract  
submitted by kickingbird at 15 days ago from Zoonoses Public Health. 2026 May 15 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.70065)
Introduction: Highly pathogenic avian influenza (HPAI) H5N1, clade 2.3.4.4b is a global threat causing widespread outbreaks on poultry farms and high mortality among wild bird populations in Canada. Wild ...

Phung Nguyen The Nguyen, Nguyen Thanh Hung, Ngo Ng. Central Nervous System Involvement by Novel Clade 2.3.2.1e H5N1 Avian Influenza Virus in a Paediatric Patient. Open Forum Infectious Diseases, 2026;, ofag283.  Abstract  
submitted by kickingbird at 15 days ago from Open Forum Infectious Diseases, 2026;, ofag283 (via https://academic.oup.com/ofid/advance-article/doi/10.1093/of)
Novel clade 2.3.2.1e A(H5N1) virus was detected in cerebrospinal fluid but not in respiratory, rectal-swab and blood samples of an eight-year-old boy presenting with meningoencephalitis without respiratory ...

Rolfes MA, Bauck L, Lipton BA, et al. Knowledge, Attitudes, and Practices Regarding Avian Influenza Among Owners of Backyard Flocks - United States, July-December 2025. Morb Mortal Wkly Rep 2026;75:234-239.  Abstract  
submitted by kickingbird at 15 days ago from Morb Mortal Wkly Rep 2026;75:234-239 (via https://www.cdc.gov/mmwr/volumes/75/wr/mm7518a2.htm)
Many U.S. households keep backyard bird flocks for their personal food supply or as garden partners. Backyard flocks in the United States have occasionally been infected with avian influenza A viruses, ...

Mengyang Zhang, etc.,al. Sunlight Inactivation of Influenza A Virus and Bacteriophages on an Acrylic Surface. Environ. Sci. Technol. 2026, 60, 16, 11960–11970.  Abstract  
submitted by kickingbird at 15 days ago from Environ. Sci. Technol. 2026, 60, 16, 11960–11970 (via https://pubs.acs.org/doi/10.1021/acs.est.5c13082)
Seasonal epidemics and pandemics of influenza cause a large public health burden, with transmission occurring via contact with contaminated fomites. Sunlight has been shown to inactivate viruses in water, ...

Andrey Coatrini-Soares, etc.,al. Microfluidic Electronic Tongue Made with Nanostructured Films of Proteins from Renewable Sources to Detect H5N1 Antibodies from Avian Influenza Virus. ACS Appl. Nano Mater. 2026, 9, 15, 6581–6590.  Abstract  
submitted by kickingbird at 15 days ago from ACS Appl. Nano Mater. 2026, 9, 15, 6581–6590 (via https://pubs.acs.org/doi/10.1021/acsanm.6c00138)
Avian influenza viruses, particularly the H5N1 subtype, represent a major global threat due to their high transmissibility and mortality rates. Rapid, low-cost, and reliable detection is essential for ...

Kota Matsumoto, etc.,al. Viral Membrane-Targeting Amphipathic Helical Peptide Ligands for Colorimetric Sandwich Assays of Influenza A Virus Particles. ACS Sens. 2026.  Abstract  
submitted by kickingbird at 15 days ago from ACS Sens. 2026 (via https://pubs.acs.org/doi/10.1021/acssensors.6c00241)
Viral membrane-binding amphipathic helical (AH) peptides were explored as detection ligands in the sandwich-type colorimetric assay for selective detection of target influenza A virus (IAV) particles, ...

Jun Jiao, etc.,al. [preprint]G4 Eurasian avian-like H1N1 swine influenza viruses exhibit enhanced pathogenicity potential in mice and pigs. https://doi.org/10.64898/2026.05.12.724537.  Abstract  
submitted by kickingbird at May, 14, 2026 from https://doi.org/10.64898/2026.05.12.724537 (via https://www.biorxiv.org/content/10.64898/2026.05.12.724537v1)
Currently circulating swine influenza viruses (SIVs) mainly include H1N1, H1N2, and H3N2 subtypes. In this study, two G4 genotype Eurasian avian-like (EA) H1N1 SIVs were isolated from 556 samples collected ...

Alejandra Garcia-Glaessner, etc.,al. [preprint]Outbreak of H9N2 avian influenza viruses in lesser rhea in Peru, June-July 2025. https://doi.org/10.64898/2026.05.08.723762.  Abstract  
submitted by kickingbird at May, 14, 2026 from https://doi.org/10.64898/2026.05.08.723762 (via https://www.biorxiv.org/content/10.64898/2026.05.08.723762v1)
Avian influenza viruses (AIVs) are endemic in the Americas and responsible for outbreaks in both domestic and wild birds that occasionally spill over into humans. We report the first known outbreak of ...

Nathaniel Jackson, etc.,al. [preprint]A single PA-X mutation in bovine-origin H5N1 influenza virus reduces pathogenicity in mice. https://doi.org/10.64898/2026.05.09.724031.  Abstract  
submitted by kickingbird at May, 14, 2026 from https://doi.org/10.64898/2026.05.09.724031 (via https://www.biorxiv.org/content/10.64898/2026.05.09.724031v1)
Dairy cows have emerged as a reservoir for human infection with highly pathogenic avian influenza (HPAI) H5N1. At the bovine–human interface, H5N1 strains may acquire adaptive mutations that influence ...

Ort, J.T., Sobel Leonard, A., Li, S.H. et al. Cross-reactive human antibody responses to H5N1 influenza virus neuraminidase are shaped by immune history. Nat Commun (2026).  Abstract  
submitted by kickingbird at May, 14, 2026 from Nat Commun (2026) (via https://link.springer.com/article/10.1038/s41467-026-72941-4)
H5N1 highly pathogenic avian influenza viruses have spread globally and pose a pandemic risk. Prior studies suggest that early life exposures to group 1 influenza viruses (H1N1 and H2N2) prime antibodies ...

Yang H, Zhang Y, Wang X, Chen T, Jia Y, Dou H, Jia. Epidemiological and Genomic Characterization of H5 Subtype Avian Influenza Viruses in Jining City, 2024–2025. Pathogens. 2026; 15(5):521.  Abstract  
submitted by kickingbird at May, 14, 2026 from Pathogens. 2026; 15(5):521 (via https://www.mdpi.com/2076-0817/15/5/521)
Objective: The aim of this study was to characterize the epidemiological features and whole-genome characteristics of H5 subtype avian influenza viruses circulating in Jining City during 2024–2025, and ...

Zhou L, Li X, Chen J, Liu Y, Zhang Y, Gong X, Meng. Screening of Low-Tumorigenic MDCK Cells for Potential Influenza Vaccine Substrates and Transcriptomic Analyses. International Journal of Molecular Sciences. 2026.  Abstract  
submitted by kickingbird at May, 14, 2026 from International Journal of Molecular Sciences. 2026 (via https://www.mdpi.com/1422-0067/27/9/3875)
Since MDCK cells are inherently tumorigenic, their safety in vaccine production has long been a concern; thus, establishing a screening method for low-tumorigenic cells is of great significance for influenza ...

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