Phung Nguyen The Nguyen, Nguyen Thanh Hung, Ngo Ng. Central Nervous System Involvement by Novel Clade 2.3.2.1e H5N1 Avian Influenza Virus in a Paediatric Patient. Open Forum Infectious Diseases, 2026;, ofag283
Novel clade 2.3.2.1e A(H5N1) virus was detected in cerebrospinal fluid but not in respiratory, rectal-swab and blood samples of an eight-year-old boy presenting with meningoencephalitis without respiratory symptoms. Cerebrospinal fluid A(H5N1)-hemagglutinin-specific antibody levels were higher than that of sera. Clinicians should be aware of emerging clade 2.3.2.1e A(H5N1) associated meningoencephalitis.
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