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2025-12-5 20:22:48
Article

Soliani L, Mescoli A, Zanni I, Baioni L, Alborali. Human-Derived H3N2 Influenza A Viruses Detected in Pigs in Northern Italy. Viruses. 2025; 17(9):1171.  Abstract  
submitted by kickingbird at Sep, 23, 2025 from Viruses. 2025; 17(9):1171 (via https://www.mdpi.com/1999-4915/17/9/1171)
In recent years, the four main swine influenza A virus (IAV-S) subtypes circulating in swine in the EU have been H1avN1, H1huN2, H1N1pdm09, and H3N2. The latter emerged in 1984 from a reassortment event ...

Chunxia Wu, etc.,al. Epidemiological investigation and analysis of the first human infection with H5N6 avian influenza in Chengdu. Strait J Prev Med, Dec. 2024, Vol.30, No.6.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from Strait J Prev Med, Dec. 2024, Vol.30, No.6 (via http://www.flu.org.cn/scn/article_detail.asp?articleId=22932)
Objective to analyze the epidemiological characteristics of the first case of human infection with H5N6 avian influenza in Chengdu, and provide references for its epidemic prevention and control.Methods ...

Huizhen Lan, etc.,al. Nursing practice of veno venous extracorporeal membrane oxygenation combined with prone position ventilation in patients with avian influenza complicated with severe acute respiratory distress syndrom. Journal of Tuberculosis and Lung Disease.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from Journal of Tuberculosis and Lung Disease (via https://doi.org/10.19983/j.issn.2096-8493.20250096)
H10N3 is a member of the genus influenza A virus and belongs to the Orthomyxoviridae family. Its genomic characteristics meet the classification criteria of subtypes of avian influenza viruses. The name ...

Dua A, Trehan B, Bilasy SE, Yang C, ElShamy A. Gastrointestinal Infiltration in Influenza Virus Infection: Mechanisms and Clinical Insights. Viruses. 2025; 17(9):1187.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from Viruses. 2025; 17(9):1187 (via https://www.mdpi.com/1999-4915/17/9/1187)
Background: Influenza, a primarily respiratory illness, frequently manifests with gastrointestinal (GI) symptoms including nausea, vomiting, diarrhea, and abdominal pain. In this review, we analyze mechanisms ...

Joshua Wiggins, Adthakorn Madapong, Eric A Weaver. [preprint]Dual-Route H5N1 Vaccination Induces Systemic and Mucosal Immunity in Murine and Bovine Models. https://doi.org/10.1101/2025.09.21.677614.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from https://doi.org/10.1101/2025.09.21.677614 (via https://www.biorxiv.org/content/10.1101/2025.09.21.677614v1)
Since its discovery in U.S. dairy cattle in early 2024, the highly pathogenic H5N1 avian influenza (clade 2.3.4.4b) has spread widely among herds, causing major economic losses. This zoonotic event emphasizes ...

Minxi Jiang, etc.,al. [preprint]Developing and Benchmarking One Health Genomic Surveillance Tools for Influenza A Virus in Wastewater. https://doi.org/10.1101/2025.09.19.676942.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from https://doi.org/10.1101/2025.09.19.676942 (via https://www.biorxiv.org/content/10.1101/2025.09.19.676942v1)
Influenza A viruses (IAV) remain a persistent One Health threat, and whole-genome sequencing from wastewater offers a promising surveillance tool. However, IAV is at low abundance in wastewater, making ...

Indr? Blagnyt?, etc.,al. [preprint]Phylogeographic analysis of Influenza D virus evolution. https://doi.org/10.1101/2025.09.19.677308.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from https://doi.org/10.1101/2025.09.19.677308 (via https://www.biorxiv.org/content/10.1101/2025.09.19.677308v1)
Influenza D virus (IDV), first identified in 2011 and primarily affecting cattle, has since been detected in a wide range of mammalian hosts and geographic regions. Despite widespread circulation in domestic ...

Rebecca M. Schneider, etc.,al. [preprint]The structures of tetrameric Avian Immunoglobulin A are uniquely structured to support mucosal immunity. https://doi.org/10.1101/2025.09.19.677352.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from https://doi.org/10.1101/2025.09.19.677352 (via https://www.biorxiv.org/content/10.1101/2025.09.19.677352v1)
Birds and mammals assemble polymeric (p) forms of immunoglobulin (Ig) A, which are transported to mucosal surfaces and released as secretory (S) IgA, the predominant mucosal antibody. Mammalian SIgA, which ...

Ulrich Knief, etc.,al. [preprint]Outbreak dynamics of high pathogenicity avian influenza virus H5N1, clade 2.3.4.4b euBB, in black-headed gulls and common terns in Germany in 2023. https://doi.org/10.1101/2025.09.17.676714.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from https://doi.org/10.1101/2025.09.17.676714 (via https://www.biorxiv.org/content/10.1101/2025.09.17.676714v1)
Since winter 2022/23, high pathogenicity avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b, genotype euBB, has caused extensive mortality among wild birds. This genotype emerged in France in spring 2022 ...

Harit D, Sawant S, Spreng RL, Gurley S, Schechter. Qualification of a reporter virus microneutralization assay for evaluation of influenza specific antibodies in human clinical trials. Vaccine. 2025 Sep 19;64:127699.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from Vaccine. 2025 Sep 19;64:127699 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
Neutralizing antibodies can block the entry of viruses into host cells. Next-generation influenza vaccines should stimulate the production of high levels of neutralizing antibodies capable of preventing ...

Kathryn Kistler, Trevor Bedford. Seasonal influenza viruses show distinct adaptive dynamics during growth in chicken eggs. Molecular Biology and Evolution, 2025;, msaf227.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from Molecular Biology and Evolution, 2025;, msaf227 (via https://academic.oup.com/mbe/advance-article/doi/10.1093/mol)
Human influenza viruses are grown in chicken eggs for vaccine production. Sequences of these egg-passaged viruses give us the opportunity to examine the evolution that occurs when these human viruses are ...

Danuta M Skowronski, etc.,al. [preprint]Cross-reactive neuraminidase inhibition antibodies against H5N1 by consecutive influenza A imprinting cohorts of the past century: population-based serosurvey, British Columbia, Canada. https://doi.org/10.1101/2025.09.19.25336209.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from https://doi.org/10.1101/2025.09.19.25336209 (via https://www.medrxiv.org/content/10.1101/2025.09.19.25336209v)
Background: Avian influenza of the H5N1 subtype shares substantial relatedness in its neuraminidase (NA) surface protein with human influenza A H1N1 viruses of the past century. Understanding variation ...

Jun-Qing Wei, Sen Zhang, Ya- Dan Li, Shu-Yang Jian. Deep learning predicts potential reassortments of avian H5N1 with human influenza viruses. National Science Review, 2025;, nwaf396.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from National Science Review, 2025;, nwaf396 (via https://academic.oup.com/nsr/advance-article/doi/10.1093/nsr)
Frequent infection cases with avian H5N1 influenza A viruses (IAVs) are posing pandemic risks of human/avian-reassorted IAVs. We aimed to build an attentional deep learning model named HAIRANGE, for predicting ...

Hoang-Hai Nguyen, Josip Rudar, Nathaniel Lesperanc. WaveSeekerNet: accurate prediction of influenza A virus subtypes and host source using attention-based deep learning. GigaScience, Volume 14, 2025, giaf089.  Abstract  
submitted by kickingbird at Sep, 22, 2025 from GigaScience, Volume 14, 2025, giaf089 (via https://academic.oup.com/gigascience/article/doi/10.1093/gig)
BackgroundInfluenza A virus (IAV) poses a significant threat to animal health globally, with its ability to overcome species barriers and cause pandemics. Rapid and accurate IAV subtypes and host source ...

Liu, L., Xia, L., Wu, B. et al. Preparation and characterization of a Llama VHH-hFc chimeric antibody recognizing conserved neutralization epitope of H5N1 hemagglutinin with high affinity. Arch Microbiol 207, 252 (2025).  Abstract  
submitted by kickingbird at Sep, 22, 2025 from Arch Microbiol 207, 252 (2025) (via https://link.springer.com/article/10.1007/s00203-025-04460-7)
Highly pathogenic avian influenza (HPAI) H5N1 virus poses a continuing global public health threat due to its outbreaks in poultry farms and zoonotic transmission from birds to humans. In the quest of ...

Wei J, Cen P, Bi D. A case of H10N3 avian influenza in a young woman. Med. 2025 Sep 18:100845.  Abstract  
submitted by kickingbird at Sep, 21, 2025 from Med. 2025 Sep 18:100845 (via https://www.cell.com/med/abstract/S2666-6340(25)00272-7)
Background: Avian influenza viruses, frequently identified in wild waterfowl and poultry, have occasionally been transmitted to humans, causing severe respiratory diseases. This report covers the fourth ...

Colombo RE, Richard SA, Schmidt K, Schofield C, Ga. Randomized pragmatic trial of the comparative effectiveness of chicken egg-based inactivated, mammalian cell-culture-based inactivated, and recombinant protein quadrivalent seasonal influenza vaccines. Clin Infect Dis. 2025 Sep 18:ciaf503.  Abstract  
submitted by kickingbird at Sep, 21, 2025 from Clin Infect Dis. 2025 Sep 18:ciaf503 (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
Background: Influenza is a major cause of morbidity and mortality worldwide. The Pragmatic Assessment of Influenza Vaccine Effectiveness (VE) in the Department of Defense (PAIVED) study compared the relative ...

Hatzl S, Kriegl L, Geiger C, Wilhelmer C, Reisinge. Empirical antifungal treatment of critically ill patients with influenza-associated acute respiratory distress syndrome: A propensity score weighted observational study. Clin Infect Dis. 2025 Sep 15:ciaf507.  Abstract  
submitted by kickingbird at Sep, 21, 2025 from Clin Infect Dis. 2025 Sep 15:ciaf507 (via https://academic.oup.com/cid/advance-article/doi/10.1093/cid)
Background: Influenza-associated pulmonary aspergillosis (IAPA) is a significant fungal complication in patients with influenza-induced acute-respiratory-distress-syndrome (ARDS). The impact of empirical ...

Chrzastek K, Lieber CM, Plemper RK. H5N1 Clade 2.3.4.4b: Evolution, Global Spread, and Host Range Expansion. Pathogens. 2025; 14(9):929.  Abstract  
submitted by kickingbird at Sep, 20, 2025 from Pathogens. 2025; 14(9):929 (via https://www.mdpi.com/2076-0817/14/9/929)
Highly pathogenic avian influenza viruses (HPAIVs) of the H5 subtype pose a continuous threat to animal and public health due to their zoonotic potential, rapid evolution, and ability to spread across ...

Lee S, Park JH, Cho H, Moon S, Ahn S. Comparison of rapid nucleic acid amplification tests and rapid antigen tests for influenza in the emergency department. Am J Emerg Med. 2025 Sep 12;99:25-30.  Abstract  
submitted by kickingbird at Sep, 20, 2025 from Am J Emerg Med. 2025 Sep 12;99:25-30 (via https://www.sciencedirect.com/science/article/pii/S073567572)
Background: Influenza is a seasonal epidemic that poses significant health risks. Early antiviral treatment is recommended, making rapid and accurate diagnostic testing essential. Although rapid antigen ...

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