Stettler, M., Hoby, S., Wenker, C. et al. RNA replicon vaccination confers long-lasting protection against H5N1 avian influenza in 23 zoo bird species. Nat Commun 16, 9245 (2025). Abstract
submitted by kickingbird at Oct, 22, 2025 from Nat Commun 16, 9245 (2025) (via https://link.springer.com/article/10.1038/s41467-025-64301-5)
Highly pathogenic avian influenza (HPAI) H5N1 viruses (clade 2.3.4.4b) cause mass mortality in birds and have infected over 50 mammalian species, including humans. Approved avian vaccines remain limited. ... Chang N, Wang H, Aisaiti K, Guo J, Wu T, Zhang C,. Complex Reassortment Dynamics of H9N2 Avian Influenza Viruses in Xinjiang, China: Implications for Zoonotic Spillover. Influenza Other Respir Viruses. 2025;19(10):e70170. Abstract
submitted by kickingbird at Oct, 21, 2025 from Influenza Other Respir Viruses. 2025;19(10):e70170 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70170)
BackgroundH9N2 avian influenza viruses (AIVs) donate their genes to other subtype AIVs, posing significant threats to poultry industries and public health due to their endemicity and zoonotic potential. ... Ailam Lim, etc.,al. [preprint]Unexpected Detection of Highly Pathogenic Avian Influenza (HPAI) H5N1 virus in bovine Semen. https://doi.org/10.1101/2025.10.16.682947. Abstract
submitted by kickingbird at Oct, 19, 2025 from https://doi.org/10.1101/2025.10.16.682947 (via https://www.biorxiv.org/content/10.1101/2025.10.16.682947v1)
Since March 2024, HPAI H5N1 virus has infected dairy cattle in the U.S., prompting concern about novel transmission routes. During an outbreak in California, HPAI H5N1 RNA was detected in an asymptomatic ... Molly C Hetherington-Rauth, etc.,al. [preprint]Targeted tiled amplicon based protocol for sequencing the Hemagglutinin (HA) gene segment of seasonal influenza A and influenza B virus from wastewater at high depth of coverage. https://doi.org/10.1101/2025.10.15.25338105. Abstract
submitted by kickingbird at Oct, 18, 2025 from https://doi.org/10.1101/2025.10.15.25338105 (via https://www.medrxiv.org/content/10.1101/2025.10.15.25338105v)
Wastewater based epidemiology has emerged as a compelling tool to monitor the spread and evolution of pathogens of public health concern. Next generation sequencing (NGS) of pathogens detected in wastewater ... Fei-fei Ge, etc.,al. Robust and sustained immunity in beagles following one single nasal administration of H3N2 canine influenza virus-like particle. Vaccine: X. Abstract
submitted by kickingbird at Oct, 18, 2025 from Vaccine: X (via https://www.sciencedirect.com/science/article/pii/S259013622)
In this study, we used baculovirus to express hemagglutinin (HA) and neuraminidase (NA) to prepare a novel genotype of H3N2 canine influenza virus particles (VLPs). The effectiveness of the H3N2 VLP vaccine ... Huibin Lv, etc.,al. Evolution of antibody cross-reactivity to influenza H5N1 neuraminidase from an N2-specific germline. Cell Host & Microbe. Abstract
submitted by kickingbird at Oct, 18, 2025 from Cell Host & Microbe (via https://www.sciencedirect.com/science/article/abs/pii/S19313)
The ongoing spread of highly pathogenic avian influenza H5N1 clade 2.3.4.4b virus in animals and its occasional spillover to humans have raised concerns about a potential H5N1 pandemic. Although recent ... Gregory L Damhorst, Wilbur A Lam. Point-of-care and Home Use Influenza Diagnostics for Advancing Therapeutic and Public Health Strategies. The Journal of Infectious Diseases, Volume 232. Abstract
submitted by kickingbird at Oct, 18, 2025 from The Journal of Infectious Diseases, Volume 232 (via https://academic.oup.com/jid/article/232/Supplement_3/S314/8)
Point-of-care (POC) antigen-based diagnostics for influenza that have been granted waived status since the Clinical Laboratory Improvement Amendments of 1988 (CLIA-waived) have been available commercially ... Madeleine R Heldman, Michael J Boeckh, Michael G I. Influenza Antivirals for Prevention and Treatment in Immunocompromised People. The Journal of Infectious Diseases, Volume 232. Abstract
submitted by kickingbird at Oct, 18, 2025 from The Journal of Infectious Diseases, Volume 232 (via https://academic.oup.com/jid/article/232/Supplement_3/S243/8)
Antivirals form a foundation for protecting immunocompromised individuals (ICIs) from influenza complications. Neuraminidase inhibitors have demonstrated benefit for both prophylaxis and treatment in ICIs, ... Lindsey E Hastings, Edward P Acosta, David W Kimbe. Influenza Antiviral Pharmacokinetic-Pharmacodynamic Relationships in Pregnancy, Infancy, and Early Childhood. The Journal of Infectious Diseases, Volume 232. Abstract
submitted by kickingbird at Oct, 18, 2025 from The Journal of Infectious Diseases, Volume 232 (via https://academic.oup.com/jid/article/232/Supplement_3/S286/8)
Owing to its decades of use among patients of all ages and health conditions, oseltamivir has the most widely described pharmacokinetics (PK) and pharmacodynamics (PD) of all the modern influenza antivirals. ... Jahid MJ, Owsiany MC, Smith LM, Foreman BM, Cao Z,. Serological Evidence of Exposure to Eurasian-Lineage HPAI H5N1 Clade 2.3.4.4b in Wild Mammals in Ohio, USA, 2024-2025. Viruses. 2025; 17(10):1388. Abstract
submitted by kickingbird at Oct, 18, 2025 from Viruses. 2025; 17(10):1388 (via https://www.mdpi.com/1999-4915/17/10/1388)
The Goose/Guandong lineage of highly pathogenic avian influenza virus [A/Goose/Guangdong/1/1996(H5N1)] is the progenitor of the currently circulating Eurasian-lineage highly pathogenic avian influenza ... Puttahonnappa, S.K., Anandakumar, J., Barman, N.N.. Investigating environmental determinants and spatiotemporal dynamics of highly pathogenic avian influenza H5N1 outbreaks in India through machine learning. Sci Rep 15, 36132 (2025). Abstract
submitted by kickingbird at Oct, 18, 2025 from Sci Rep 15, 36132 (2025) (via https://link.springer.com/article/10.1038/s41598-025-96765-2)
Avian Influenza (AI), caused by highly pathogenic strains of influenza viruses, poses a significant threat to poultry populations and public health worldwide. This study offers a comprehensive evaluation ... Liu Z, Guo J, Zhang C, Ding Y, Sun S, Yao B, Xing. Computational Discovery of Potent Nucleoprotein Inhibitors for Influenza A Virus: Validation Through QM/MM Analysis and Experimental Binding Assays. Molecules. 2025; 30(19):3960. Abstract
submitted by kickingbird at Oct, 17, 2025 from Molecules. 2025; 30(19):3960 (via https://www.mdpi.com/1420-3049/30/19/3960)
This study employed an integrated computational approach to discover novel nucleoprotein (NP) inhibitors for influenza A virus (IAV). Beginning with virtual screening of over 10 million compounds using ... Hepp C, Zhao Q, Robb N, Fodor E, Kapanidis AN. High-throughput single-virion DNA-PAINT reveals structural diversity, cooperativity, and flexibility during selective packaging in influenza. Nucleic Acids Res. 2025 Oct 14;53(19):gkaf1020. Abstract
submitted by kickingbird at Oct, 17, 2025 from Nucleic Acids Res. 2025 Oct 14;53(19):gkaf1020 (via https://academic.oup.com/nar/article/53/19/gkaf1020/8285782)
Influenza A, a negative-sense RNA virus, has a genome that consists of eight single-stranded RNA segments. Influenza co-infections can result in reassortant viruses that contain gene segments from multiple ... Hui DSC, Chan KKP. Host Immunomodulatory Interventions in Severe Influenza. J Infect Dis. 2025 Oct 17;232(Supplement_3):S262-S. Abstract
submitted by kickingbird at Oct, 17, 2025 from J Infect Dis. 2025 Oct 17;232(Supplement_3):S262-S (via https://academic.oup.com/jid/article/232/Supplement_3/S262/8)
Currently, no immunomodulatory agents have been conclusively shown to benefit severe influenza. The World Health Organization conditionally advises against the use of systemic corticosteroids, macrolides, ... Takashita E, Wolfe CR, Jones JC. Laboratory Methods for Monitoring Influenza Antiviral Resistance. J Infect Dis. 2025 Oct 17;232(Supplement_3):S273-. Abstract
submitted by kickingbird at Oct, 17, 2025 from J Infect Dis. 2025 Oct 17;232(Supplement_3):S273- (via https://academic.oup.com/jid/article-abstract/232/Supplement)
Monitoring antiviral susceptibility is an essential component of virologic surveillance conducted by laboratories participating in the World Health Organization (WHO) Global Influenza Surveillance and ... Yang J, Sun J, Zhao D, Liu J, Ma M, Wang Q, Bi Y. Reassortment risk of clade 2.3.4.4b H5N1 with avian H9N2 and human H3N2 and H1N1 influenza A viruses. Sci Bull (Beijing). 2025 Sep 23:S2095-9273(25)0097. Abstract
submitted by kickingbird at Oct, 17, 2025 from Sci Bull (Beijing). 2025 Sep 23:S2095-9273(25)0097 (via https://www.sciencedirect.com/science/article/abs/pii/S20959)
Since 2021, clade 2.3.4.4b H5N1 highly pathogenic avian influenza viruses(AIVs) have become the dominant strain responsible for the ongoing panzootics in birds worldwide, causing unprecedented deaths of ... Chen LL, Ip JD, Chan WM, Lam SJ, Leung RC, Yip CC,. Enhanced replication of a contemporary avian influenza A H9N2 virus in human respiratory organoids. Emerg Microbes Infect. 2025 Oct 16:2576574. Abstract
submitted by kickingbird at Oct, 17, 2025 from Emerg Microbes Infect. 2025 Oct 16:2576574 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
H9N2 is currently the second most common avian influenza A virus subtype infecting humans. Monitoring viral phenotypic and genotypic adaptation to humans is crucial for risk assessment. Here, we compared ... Christin Hennig, etc.,al. High serological barriers may contribute to restricted Influenza-A-virus transmission between pigs and humans. One Health. Abstract
submitted by kickingbird at Oct, 16, 2025 from One Health (via https://www.sciencedirect.com/science/article/pii/S235277142)
Influenza A viruses (IAV) circulate in both humans and pigs, with bidirectional transmission potentially driving viral evolution. Despite frequent contact and genetic compatibility, observed cross-species ... Akeno Tsuneki-Tokunaga, etc.,al. Epidemic Influenza Virus Strains with High Growth Capability induce Severe Inflammatory Response in Vivo. Virology. Abstract
submitted by kickingbird at Oct, 16, 2025 from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Influenza epidemics occur worldwide and impose a substantial socioeconomic burden. In our previous studies, epidemic influenza virus strains isolated from seasonal influenza patient specimens exhibited ... Ayora-Talavera G, López-Martínez I, Barrera-Badill. Genetic and Serological Analysis of H7N3 Avian Influenza Viruses in Mexico for Pandemic Risk Assessment. Viruses. 2025; 17(10):1376. Abstract
submitted by kickingbird at Oct, 16, 2025 from Viruses. 2025; 17(10):1376 (via https://www.mdpi.com/1999-4915/17/10/1376)
Avian influenza A viruses pose ongoing threats to human and animal health, with H7 subtypes causing outbreaks globally. In Mexico, highly pathogenic H7N3 viruses have circulated in poultry since 2012, ... 6469 items, 20/Page, Page[8/324][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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