An SH, Myagmarsuren T, Heo GB, Jeong H, Kang YM, D. Clade 2.3.4.4b H5N1 highly pathogenic avian influenza detected in wild bird feces, Eastern Mongolia, 2024. J Vet Sci. 2026 Jul;27(4):e38. Abstract
submitted by kickingbird at Aug, 6, 2026 from J Vet Sci. 2026 Jul;27(4):e38 (via https://vetsci.org/DOIx.php?id=10.4142/jvs.25274)
Importance: Despite ongoing intercontinental spread of clade 2.3.4.4b H5N1 highly pathogenic avian influenza (HPAI), surveillance data from Mongolia -- a critical junction between Central and East Asian ... Lilith F Allen, etc.,al. CD4 T-cell responses directed towards A/H5N1-derived haemagglutinin peptides increase in patients with seasonal influenza A virus infection. Clinical & Translational Immunology. Abstract
submitted by kickingbird at Aug, 5, 2026 from Clinical & Translational Immunology (via https://onlinelibrary.wiley.com/doi/10.1002/cti2.70118)
ObjectivesRecent outbreak of influenza A/H5N1 viral infections in birds and mammals worldwide prompted renewed concerns over an emerging H5N1-related influenza pandemic in the generally immunologically-naive ... Cui S, Hou X, Pu S, Luo J, Zhu H, He P, Gao C, Gao. Identification and characterization of PB2 mutations associated with mammalian adaptation of highly pathogenic H5N1 avian influenza viruses. Front. Microbiol., 29 July 2026. Abstract
submitted by kickingbird at Aug, 4, 2026 from Front. Microbiol., 29 July 2026 (via https://www.frontiersin.org/journals/microbiology/articles/1)
The highly pathogenic avian influenza virus (HPAIV) subtype H5N1 has been continuously circulating among wild bird populations and domestic poultry. It’s ongoing circulation has led to outbreaks in poultry ... Pang, Z., Zhong, P., Mai, C., Fan, J., Wu, Y., Zha. Genetic evolution, phylodynamics, geographic spread of H9N2 avian influenza viruses in China from 2014 to 2025: an increasing potential zoonotic risk. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Aug, 4, 2026 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Subtype H9N2 of the avian influenza virus (AIV) poses a growing threat to the poultry industry and public health. However, since 2014, there has been no systematic study of its genetic evolution, genotype, ... Yan, Y. M. C., Li, Z., He, H., Wu, M., Yang, H. Lactylation in influenza a virus infection: Current evidence, knowledge gaps, and future perspectives. Virulence, 17(1). Abstract
submitted by kickingbird at Aug, 3, 2026 from Virulence, 17(1) (via https://www.tandfonline.com/doi/full/10.1080/21505594.2026.2)
Influenza A virus (IAV) is a major respiratory pathogen causing seasonal epidemics and pandemics, posing serious threats to public health and livestock. The high mutation rate of IAV leads to vaccine mismatches ... Zhao, Z., Tian, Y., Jiang, W., Yin, X., Chu, X., X. D347G in PA is critical for the pathogenicity of H9N2 avian influenza A virus in mice. Virulence, 17(1). Abstract
submitted by kickingbird at Aug, 3, 2026 from Virulence, 17(1) (via https://www.tandfonline.com/doi/full/10.1080/21505594.2026.2)
Some subtypes of avian influenza A viruses (IAVs) have been associated with human infections (e.g. H3N8, H5Ny, H7Ny, H9N2, and H10Ny), and the ability of these viruses to cause zoonotic infections further ... Alberto Florez Prada, etc.,al. [preprint]Affinity-enhanced peptides delivered by mRNA-LNPs inhibit influenza A virus replication by disrupting the PA-PB1 interaction. https://doi.org/10.64898/2026.07.29.740963. Abstract
submitted by kickingbird at Aug, 3, 2026 from https://doi.org/10.64898/2026.07.29.740963 (via https://www.biorxiv.org/content/10.64898/2026.07.29.740963v2)
Seasonal influenza causes up to 650,000 deaths annually and remains a persistent pandemic threat due to zoonotic strains crossing the species barrier. Current antivirals, which target neuraminidase or ... Justin Bahl, etc.,al. [preprint]Standing HA phenotypic breadth shapes H5N1 cross-host potential. https://doi.org/10.21203/rs.3.rs-10349790/v1. Abstract
submitted by kickingbird at Aug, 3, 2026 from https://doi.org/10.21203/rs.3.rs-10349790/v1 (via https://www.researchsquare.com/article/rs-10349790/v1)
Linking genetic variation to functional phenotype remains a major barrier to assessing the cross-host potential of emerging viruses. Here, we reconstruct the evolution of predicted hemagglutinin (HA) phenotypic ... Yunlong Dou, etc.,al. Subclass switching enhances protective efficacy of a non-neutralizing H7N9 avian influenza antibody. Veterinary Microbiology. Abstract
submitted by kickingbird at Aug, 3, 2026 from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Non-neutralizing antibodies contribute to protection against the H7N9 subtype avian influenza virus through Fc effector functions. Antibody subclass plays a critical role in determining binding affinity ... Bernadeta Dadonaite, etc.,al. [preprint]Defining the molecular interaction between influenza hemagglutinin and MHC-II. https://doi.org/10.64898/2026.07.17.738765. Abstract
submitted by kickingbird at Aug, 2, 2026 from https://doi.org/10.64898/2026.07.17.738765 (via https://www.biorxiv.org/content/10.64898/2026.07.17.738765v1)
The hemagglutinin (HA) of some influenza viruses can interact with major histocompatibility complex class II (MHC-II), but how these proteins interact is unclear. Here we demonstrate that diverse H5 HAs ... Heather M. Machkovech, etc.,al. [preprint]Evolutionary constraints limit additional mammalian adaptation of bovine-derived H5N1 influenza viruses in ferrets. https://doi.org/10.64898/2026.07.20.739655. Abstract
submitted by kickingbird at Aug, 2, 2026 from https://doi.org/10.64898/2026.07.20.739655 (via https://www.biorxiv.org/content/10.64898/2026.07.20.739655v1)
The outbreak of clade 2.3.4.4b H5N1 viruses among U.S. dairy cattle has raised concerns that sustained circulation among agricultural mammals could facilitate viral adaptation toward efficient human transmission. ... Hernandez-Gonzalez KM, Carranza-Aranda AS, Mu?oz-V. Molecular Characterization of Influenza A(H3N2) Hemagglutinin Variants Circulating in Western Mexico, 2022. International Journal of Molecular Sciences. 2026;. Abstract
submitted by kickingbird at Aug, 1, 2026 from International Journal of Molecular Sciences. 2026; (via https://www.mdpi.com/1422-0067/27/15/6833)
Influenza A(H3N2) remains a significant public health threat due to its rapid antigenic drift, which often compromises vaccine effectiveness. This study characterized the molecular and epidemiological ... Volkhin IA, Dashian MA, Lukashev AN, Shipulin GA,. Assessment of Quantitative Genetic Distances Supports the Separation of H17N10 and H18N11 Subtypes of Influenza A Virus into a Distinct Species. Viruses. 2026; 18(8):838. Abstract
submitted by kickingbird at Jul, 31, 2026 from Viruses. 2026; 18(8):838 (via https://www.mdpi.com/1999-4915/18/8/838)
The taxonomic status of the H17N10 and H18N11 influenza A viruses isolated from bats remains unclear due to the absence of quantitative classification criteria at this taxonomic level. A total of 3328 ... Li Y, Song X, Gao T, Wang G, Wei H, Wang J, Jiang. Genetic and Pathogenicity Studies of Avian Influenza (H9N2) Virus Isolated from Chickens in Jiangsu Province, China, in 2025. Microorganisms. 2026; 14(8):1667. Abstract
submitted by kickingbird at Jul, 31, 2026 from Microorganisms. 2026; 14(8):1667 (via https://www.mdpi.com/2076-2607/14/8/1667)
In this study, one H9N2 subtype avian influenza virus (AIV) was isolated in Jiangsu Province, China, in March 2025. According to phylogenetic analysis, the HA gene fragment of the H9N2 isolate was classified ... Vidanovi? D, Maleti? J, ?ekler M, Te?ovi? B, Vasko. Complete coding sequence of influenza A virus subtype H1N3 from guinea fowl in Republic of Serbia. Microbiol Resour Announc. 2026 Jul 29:e0021326. Abstract
submitted by kickingbird at Jul, 30, 2026 from Microbiol Resour Announc. 2026 Jul 29:e0021326 (via https://journals.asm.org/doi/10.1128/mra.00213-26)
Here, we report the complete coding sequence of the avian influenza A virus subtype H1N3 from guinea fowl [A/Guinea fowl/Serbia/Vinca_household/2025(H1N3)] obtained on the Oxford Nanopore Technologies ... Ksenia Sukhova, etc.,al. [preprint]Mutations in severe human H5N1 cases facilitate evasion from human mucus and antivirals. https://doi.org/10.64898/2026.07.28.740943. Abstract
submitted by kickingbird at Jul, 29, 2026 from https://doi.org/10.64898/2026.07.28.740943 (via https://www.biorxiv.org/content/10.64898/2026.07.28.740943v1)
In late 2024, two individuals in Canada and the United States were treated in intensive care for acute respiratory distress caused by infection with the avian Influenza A Virus H5N1 2.3.4.4b genotype D1.1. ... Taylor Pursell, etc.,al. [preprint]H5N1 influenza binding and cell entry via human class II MHC, and blocking by cross-reactive antibodies. https://doi.org/10.64898/2026.07.22.739677. Abstract
submitted by kickingbird at Jul, 29, 2026 from https://doi.org/10.64898/2026.07.22.739677 (via https://www.biorxiv.org/content/10.64898/2026.07.22.739677v1)
Highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b viruses are currently responsible for a multi-species outbreak affecting wild birds, poultry, numerous mammalian species, and humans. Influenza ... Yunfei Wang, Fabiola Vacca, Wes Rountree, Kevin Wi. [preprint]Characterization of Influenza A HA and NA Subtypes Using Protein Sequences. https://doi.org/10.64898/2026.07.22.740123. Abstract
submitted by kickingbird at Jul, 29, 2026 from https://doi.org/10.64898/2026.07.22.740123 (via https://www.biorxiv.org/content/10.64898/2026.07.22.740123v1)
Motivation Influenza is an infectious disease associated with excess human deaths. For influenza A virus (IAV), the surface antigens hemagglutinin (HA) and neuraminidase (NA) define the specific subtype. ... Laura Mojsiejczuk, etc.,al. [preprint]Flu Mutation Explorer: an Interactive Platform for Mapping Host Adaptation Mutations in Influenza A Viruses. https://doi.org/10.64898/2026.07.22.740012. Abstract
submitted by kickingbird at Jul, 29, 2026 from https://doi.org/10.64898/2026.07.22.740012 (via https://www.biorxiv.org/content/10.64898/2026.07.22.740012v1)
A rapid expansion of influenza A virus (IAV) genome sequencing has transformed global surveillance but has also created major challenges for interpreting the biological significance of viral mutations, ... Lara S. U. Schwab, etc.,al. [preprint]Epistasis facilitates the long-term antigenic evolution of the influenza B virus hemagglutinin. https://doi.org/10.64898/2026.07.22.739994. Abstract
submitted by kickingbird at Jul, 29, 2026 from https://doi.org/10.64898/2026.07.22.739994 (via https://www.biorxiv.org/content/10.64898/2026.07.22.739994v1)
The antigenic drift of viral glycoproteins must be balanced by purifying selection pressure to maintain functionality. Understanding these evolutionary processes is key to predicting and combating viral ... 7180 items, 20/Page, Page[8/359][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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