Kei Miyakawa, etc.,al. [preprint]Rapid neutralizing assay for circulating H5N1 influenza virus in dairy cows. https://doi.org/10.1101/2024.07.30.605731. Abstract
submitted by kickingbird at Aug, 11, 2024 from https://doi.org/10.1101/2024.07.30.605731 (via https://www.biorxiv.org/content/10.1101/2024.07.30.605731v1)
A rapid and safe neutralization assay is required for emerging highly pathogenic avian influenza viruses, including the H5N1 subtype, which was recently found in cows. Herein, we report a novel neutralization ... Yuan L, Zhang S, Bi R, Liu X, Han Z, Li M, Liao X,. A broad-spectrum multiepitope vaccine against seasonal influenza A and B viruses in mice. EBioMedicine. 2024 Aug 6;106:105269. Abstract
submitted by kickingbird at Aug, 11, 2024 from EBioMedicine. 2024 Aug 6;106:105269 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: Influenza viruses pose a persistent threat to global public health, necessitating the development of innovative and broadly effective vaccines.Methods: This study focuses on a multiepitope ... Han Z, Mai Q, Zhao Y, Liu X, Cui M, Li M, Chen Y,. Mosaic neuraminidase-based vaccine induces antigen-specific T cell responses against homologous and heterologous influenza viruses. Antiviral Res. 2024 Aug 6;230:105978. Abstract
submitted by kickingbird at Aug, 11, 2024 from Antiviral Res. 2024 Aug 6;230:105978 (via https://www.sciencedirect.com/science/article/abs/pii/S01663)
Seasonal influenza is an annually severe crisis for global public health, and an ideal influenza vaccine is expected to provide broad protection against constantly drifted strains. Compared to highly flexible ... Huang L, Tang W, He L, Li M, Lin X, Hu A, Huang X,. Engineered probiotic Escherichia coli elicits immediate and long-term protection against influenza A virus in mice. Nat Commun. 2024 Aug 9;15(1):6802. Abstract
submitted by kickingbird at Aug, 11, 2024 from Nat Commun. 2024 Aug 9;15(1):6802 (via https://www.nature.com/articles/s41467-024-51182-3)
Influenza virus infection remains a major global health problem and requires a universal vaccine with broad protection against different subtypes as well as a rapid-response vaccine to provide immediate ... Adinda Kok, etc.,al. [preprint]A vaccine antigen central in influenza A(H5) virus antigenic space confers subtype-wide immunity. https://doi.org/10.1101/2024.08.06.606696. Abstract
submitted by kickingbird at Aug, 8, 2024 from https://doi.org/10.1101/2024.08.06.606696 (via https://www.biorxiv.org/content/10.1101/2024.08.06.606696v1)
Highly pathogenic avian influenza A(H5) viruses globally impact wild and domestic birds, and mammals, including humans, underscoring their pandemic potential. The antigenic evolution of the A(H5) hemagglutinin ... Zhang J, Wu Y, Wang Y, Liu P, Liu K, Sun J, Zhang. Influenza A virus infection activates STAT3 to enhance SREBP2 expression, cholesterol biosynthesis, and virus replication. iScience. 2024 Jun 29;27(8):110424. Abstract
submitted by kickingbird at Aug, 8, 2024 from iScience. 2024 Jun 29;27(8):110424 (via https://www.cell.com/iscience/fulltext/S2589-0042(24)01649-3)
Cellular cholesterol plays an important role in influenza A virus (IAV) endocytosis and replication. However, how IAV infection regulates cholesterol biosynthesis remains poorly understood. Here, we report ... Bi Y, Yang J, Wang L, Ran L, Gao GF. Ecology and evolution of avian influenza viruses. Curr Biol. 2024 Aug 5;34(15):R716-R721. Abstract
submitted by kickingbird at Aug, 8, 2024 from Curr Biol. 2024 Aug 5;34(15):R716-R721 (via https://www.cell.com/current-biology/fulltext/S0960-9822(24))
Four types of influenza virus have been identified in nature: influenza A, B, and C viruses are capable of infecting humans, and influenzas A and B cause annual epidemics (seasonal flu) in humans; however, ... Maida CM, Mazzucco W, Priano W, Palermo R, Grazian. Detection of influenza virus in urban wastewater during the season 2022/2023 in Sicily, Italy. Front Public Health. 2024 Jul 23;12:1383536. Abstract
submitted by kickingbird at Aug, 8, 2024 from Front Public Health. 2024 Jul 23;12:1383536 (via https://www.frontiersin.org/journals/public-health/articles/)
Introduction: Seasonal influenza generally represents an underestimated public health problem with significant socioeconomic implications. Monitoring and detecting influenza epidemics are important tasks ... Hew YL, Hiono T, Monne I, Nabeshima K, Sakuma S, K. Cocirculation of Genetically Distinct Highly Pathogenic Avian Influenza H5N5 and H5N1 Viruses in Crows, Hokkaido, Japan. Emerg Infect Dis. 2024 Aug 6;30(9). Abstract
submitted by kickingbird at Aug, 7, 2024 from Emerg Infect Dis. 2024 Aug 6;30(9) (via https://wwwnc.cdc.gov/eid/article/30/9/24-0356_article)
We isolated highly pathogenic avian influenza (HPAI) H5N5 and H5N1 viruses from crows in Hokkaido, Japan, during winter 2023-24. They shared genetic similarity with HPAI H5N5 viruses from northern Europe ... Liu L, Wang F, Wu Y, Mi W, Zhang Y, Chen L, Wang D. The V223I substitution in hemagglutinin reduces the binding affinity to human-type receptors while enhancing the thermal stability of the H3N2 canine influenza virus. Front Microbiol. 2024 Jul 22;15:1442163. Abstract
submitted by kickingbird at Aug, 7, 2024 from Front Microbiol. 2024 Jul 22;15:1442163 (via https://www.frontiersin.org/journals/microbiology/articles/1)
Given the intimate relationship between humans and dogs, the H3N2 canine influenza viruses (CIVs) pose a threat to public health. In our study, we isolated four H3N2 CIVs from 3,758 dog nasal swabs in ... Cui X, Vervaeke P, Gao Y, Opsomer L, Sun Q, Snoeck. Immunogenicity and biodistribution of lipid nanoparticle formulated self-amplifying mRNA vaccines against H5 avian influenza. NPJ Vaccines. 2024 Aug 3;9(1):138. Abstract
submitted by kickingbird at Aug, 6, 2024 from NPJ Vaccines. 2024 Aug 3;9(1):138 (via https://www.nature.com/articles/s41541-024-00932-x)
This study reports on the immunogenicity and biodistribution of H5 hemagglutinin (HA)-based self-amplifying (sa) mRNA vaccines in mice. Four sa-mRNA vaccines encoding either a secreted full-length HA, ... Liu DJ, Zhong XQ, Ru YX, Zhao SL, Liu CC, Tang YB,. Disulfide-stabilized Trimeric Hemagglutinin Ectodomains Provide Enhanced Heterologous Influenza Protection. Emerg Microbes Infect. 2024 Aug 5:2389095. Abstract
submitted by kickingbird at Aug, 6, 2024 from Emerg Microbes Infect. 2024 Aug 5:2389095 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Influenza virus infection poses a continual menace to public health. Here, we developed soluble trimeric HA ectodomain vaccines by establishing interprotomer disulfide bonds in the stem region, which effectively ... Chen SS, Yang YL, Wang HY, Guo TK, Azeem RM, Shi C. CRISPR/Cas13a-based genome editing for establishing the detection method of H9N2 subtype avian influenza virus. Poult Sci. 2024 Jul 9;103(10):104068. Abstract
submitted by kickingbird at Aug, 5, 2024 from Poult Sci. 2024 Jul 9;103(10):104068 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza virus (AIV) subtype H9N2 has significantly threatened the poultry business in recent years by having become the predominant subtype in flocks of chickens, ducks, and pigeons. In addition, ... Cargnin Faccin F, Cáceres CJ, Gay LC, Seibert B, v. Mass vaccination with reassortment-impaired live H9N2 avian influenza vaccine. NPJ Vaccines. 2024 Aug 3;9(1):136. Abstract
submitted by kickingbird at Aug, 5, 2024 from NPJ Vaccines. 2024 Aug 3;9(1):136 (via https://www.nature.com/articles/s41541-024-00923-y)
Avian influenza poses a severe threat to poultry production and global food security, prompting the development of vaccination programs in numerous countries. Modified live virus (MLV) vaccines, with their ... Jefferson J.S. Santos, etc.,al. [preprint]Bovine H5N1 influenza virus binds poorly to human-type sialic acid receptors. https://doi.org/10.1101/2024.08.01.606177. Abstract
submitted by kickingbird at Aug, 5, 2024 from https://doi.org/10.1101/2024.08.01.606177 (via https://www.biorxiv.org/content/10.1101/2024.08.01.606177v1)
Clade 2.3.4.4b highly pathogenic H5N1 avian influenza (HPAI) viruses started circulating widely in lactating dairy cattle in the United States at the end of 2023. Avian influenza viruses enter cells after ... Bhattacharya A, Bagheri N, Boxer SG. A Fluorogenic Pseudoinfection Assay to Probe Transfer and Distribution of Influenza Viral Contents to Target Vesicles. Anal Chem. 2024 Jul 31. Abstract
submitted by kickingbird at Aug, 3, 2024 from Anal Chem. 2024 Jul 31 (via https://pubs.acs.org/doi/10.1021/acs.analchem.4c01142)
Fusion of enveloped viruses with endosomal membranes and subsequent release of the viral genome into the cytoplasm are crucial to the viral infection cycle. It is often modeled by performing fusion between ... Cao L, She Z, Zhao Y, Cheng C, Li Y, Xu T, Mao H,. Inhibition of RAN Attenuates Influenza A Virus Replication and Nucleoprotein Nuclear Export. Emerg Microbes Infect. 2024 Aug 1:2387910. Abstract
submitted by kickingbird at Aug, 3, 2024 from Emerg Microbes Infect. 2024 Aug 1:2387910 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Nuclear export of the viral ribonucleoprotein (vRNP) is a critical step in the influenza A virus (IAV) life cycle and may be an effective target for the development of anti- IAV drugs. The host factor ... Kwon T, Artiaga BL, McDowell CD, Whitworth KM, Wel. Gene editing of pigs to control influenza A virus infections. Emerg Microbes Infect. 2024 Jul 31:2387449. Abstract
submitted by kickingbird at Aug, 2, 2024 from Emerg Microbes Infect. 2024 Jul 31:2387449 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Proteolytic activation of the hemagglutinin (HA) glycoprotein by host cellular proteases is pivotal for influenza A virus (IAV) infectivity. Highly pathogenic avian influenza viruses possess the multibasic ... Ismaila Shittu, etc.,al. [preprint]A One Health Investigation into H5N1 Avian Influenza Virus Epizootics on Two Dairy Farms. https://doi.org/10.1101/2024.07.27.24310982. Abstract
submitted by kickingbird at Aug, 1, 2024 from https://doi.org/10.1101/2024.07.27.24310982 (via https://www.medrxiv.org/content/10.1101/2024.07.27.24310982v)
Background: In early April 2024 we studied two Texas dairy farms which had suffered incursions of H5N1 highly pathogenic avian influenza virus (HPAIV) the previous month. Methods: We employed molecular ... Li X, Xie Z, Wei Y, Li M, Zhang M, Luo S, Xie L. Recombinant Hemagglutinin Protein from H9N2 Avian Influenza Virus Exerts Good Immune Effects in Mice. Microorganisms. 2024; 12(8):1552. Abstract
submitted by kickingbird at Jul, 30, 2024 from Microorganisms. 2024; 12(8):1552 (via https://www.mdpi.com/2076-2607/12/8/1552)
The H9N2 subtype of avian influenza virus (AIV) causes enormous economic losses and poses a significant threat to public health; the development of vaccines against avian influenza is ongoing. To study ... 6469 items, 20/Page, Page[56/324][|<<] [|<] [51] [52] [53] [54] [55] [56] [57] [58] [59] [60] [>|] [>>|] |
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