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2025-12-5 16:16:10
Article

Ding X, Ma Y, Li S, Liu J, Qin L, Wu A. Influenza virus reassortment patterns exhibit preference and continuity while uncovering cross-species transmission events. Brief Bioinform. 2025 May 1;26(3):bbaf233.  Abstract  
submitted by kickingbird at May, 23, 2025 from Brief Bioinform. 2025 May 1;26(3):bbaf233 (via https://academic.oup.com/bib/article/26/3/bbaf233/8140404)
Genomic reassortment is a key driver of influenza virus evolution and a major factor in pandemic emergence, as reassorted strains can exhibit significantly altered antigenicity. However, due to technical ...

Alkie TN, Embury-Hyatt C, Signore AV, Baldwin F, H. Comparative pathogenicity of three A(H5N1) clade 2.3.4.4b HPAI viruses in blue-winged teal and transmission to domestic poultry. mSphere. 2025 May 22:e0002125.  Abstract  
submitted by kickingbird at May, 23, 2025 from mSphere. 2025 May 22:e0002125 (via https://journals.asm.org/doi/10.1128/msphere.00021-25)
Long-distance migratory ducks play a critical role in the maintenance and dissemination of A(H5N1) viruses. Comparative pathogenicity studies were conducted on blue-winged teal (BWTE; Anas discors) using ...

X Wen, etc.,al. [preprint]Fatal infection of a novel canine/human reassortant H3N2 influenza A virus in the zoo-housed golden monkeys. https://doi.org/10.21203/rs.3.rs-6582619/v1.  Abstract  
submitted by kickingbird at May, 22, 2025 from https://doi.org/10.21203/rs.3.rs-6582619/v1 (via https://www.researchsquare.com/article/rs-6582619/v1)
Influenza A virus (IAV) is one of the most challenging pathogens that threaten human and animal health. In June 2022, seven golden monkeys (Rhinopithecus roxellanaes) developed flu-like symptoms in succession ...

Kwon, T., Trujillo, J. D., Carossino, M., Machkove. Pathogenicity and transmissibility of bovine-derived HPAI H5N1 B3.13 virus in pigs. Emerg Microbes Infect. 2025 May 21:2509742.  Abstract  
submitted by kickingbird at May, 22, 2025 from Emerg Microbes Infect. 2025 May 21:2509742 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Since the first emergence of highly pathogenic avian influenza (HPAI) H5N1 viruses in dairy cattle, the virus has continued to spread, reaching at least 17 states and at least 950 dairy herds in the United ...

Simmons HC, Finney J, Kotaki R, Adachi Y, Moseman. A protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface. mBio. 2025 May 20:e0089225.  Abstract  
submitted by kickingbird at May, 21, 2025 from mBio. 2025 May 20:e0089225 (via https://journals.asm.org/doi/10.1128/mbio.00892-25)
Influenza infection and vaccination impart strain-specific immunity that protects against neither seasonal antigenic variants nor the next pandemic. However, antibodies directed to conserved sites can ...

Yan C, Shi J, Cui P, Chen Y, Wang C, Wang Y, Miao. Characterization of emerging H3N3 avian influenza viruses in poultry in China. Emerg Microbes Infect. 2025 May 20:2509748.  Abstract  
submitted by kickingbird at May, 21, 2025 from Emerg Microbes Infect. 2025 May 20:2509748 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Avian influenza viruses continue to challenge poultry and human health; therefore, careful surveillance and evaluation of emerging viruses are important for animal disease control and human influenza pandemic ...

Zheng Z, Chen X, Zheng R, Yan Z, Li L, Chen R, Li. Progressive Adaptation of Subtype H6N1 Avian Influenza Virus in Taiwan Enhances Mammalian Infectivity, Pathogenicity, and Transmissibility. Viruses. 2025; 17(5):733.  Abstract  
submitted by kickingbird at May, 21, 2025 from Viruses. 2025; 17(5):733 (via https://www.mdpi.com/1999-4915/17/5/733)
The interspecies transmission of avian influenza viruses remains a significant public health concern. H6 viruses have gained attention following the first human infection by a chicken-origin H6N1 virus ...

Diego Carvalho do Nascimento, Mauricio Ulloa, Romu. [preprint]Chilean Avian flu and its marine impacts: an online Statistical Process Control task. https://doi.org/10.48550/arXiv.2505.08629.  Abstract  
submitted by kickingbird at May, 19, 2025 from https://doi.org/10.48550/arXiv.2505.08629 (via https://arxiv.org/abs/2505.08629)
The rapid spread of the HPAI H5N1 virus, responsible for the Avian Flu, is causing a great catastrophe on the South American Pacific coast (especially in the south of Peru and north of Chile). Although ...

You Chang, etc.,al. [preprint]Assessing the Spatial and Temporal Risk of HPAIV Transmission to Danish Cattle via Wild Birds. https://doi.org/10.48550/arXiv.2504.12432.  Abstract  
submitted by kickingbird at May, 19, 2025 from https://doi.org/10.48550/arXiv.2504.12432 (via https://arxiv.org/abs/2504.12432)
A highly pathogenic avian influenza (HPAI) panzootic has severely impacted wild bird populations worldwide, with documented (zoonotic) transmission to mammals, including humans. Ongoing HPAI outbreaks ...

Jonathan Heeney, etc.,al. [preprint]Digitally Immune-Optimised Next-Generation Influenza Vaccine Provides Cross-Clade Protection Against Emerging H5Nx Viruses. https://doi.org/10.21203/rs.3.rs-6647740/v1.  Abstract  
submitted by kickingbird at May, 19, 2025 from https://doi.org/10.21203/rs.3.rs-6647740/v1 (via https://www.researchsquare.com/article/rs-6647740/v1)
A panzootic of H5Nx avian influenza viruses has severely affected poultry and wild bird populations resulting in multiple mammalian spillovers, including human infections caused by antigenically distinct ...

de Jong, S.P.J., Conlan, A.J.K., Han, A.X. et al. Competition between transmission lineages mediated by human mobility shapes seasonal influenza epidemics in the US. Nat Commun 16, 4605 (2025).  Abstract  
submitted by kickingbird at May, 19, 2025 from Nat Commun 16, 4605 (2025) (via https://www.nature.com/articles/s41467-025-59757-4)
Due to its climatic variability, complex mobility networks and geographic expanse, the United States represents a compelling setting to explore the transmission processes that lead to heterogeneous yearly ...

Andrea Arroyave, etc.,al. [preprint]Assessment of cross-reactive neutralizing antibodies induction against H5N1 clade 2.3.4.4b by prior seasonal influenza immunization in retail workers. https://doi.org/10.1101/2025.05.15.25327718.  Abstract  
submitted by kickingbird at May, 17, 2025 from https://doi.org/10.1101/2025.05.15.25327718 (via https://www.medrxiv.org/content/10.1101/2025.05.15.25327718v)
Highly pathogenic avian influenza (HPAI) H5N1 has been a global concern since its emergence in 1997, causing widespread outbreaks in birds and sporadic human infections. The clade 2.3.4.4b H5N1 virus has ...

Hu W, Liu Y, Dong J, Peng X, Yang C, Wang H, Chen. Evaluation of a Machine Learning Model Based on Laboratory Parameters for the Prediction of Influenza A and B in Chongqing, China: Multicenter Model Development and Validation Study. J Med Internet Res. 2025 May 15;27:e67847.  Abstract  
submitted by kickingbird at May, 17, 2025 from J Med Internet Res. 2025 May 15;27:e67847 (via https://www.jmir.org/2025/1/e67847)
Background: Influenza viruses are major pathogens responsible for acute respiratory infections in humans, which present with symptoms such as fever, cough, sore throat, muscle pain, and fatigue. While ...

Páez-Hernández ZY, Stephano-Hornedo JL, Bola?os-Pr. Neutralization of the Pandemic Influenza A/H1N1 Virus with Lama glama Humanized Nanobodies (VHH). Antibodies. 2025; 14(2):42.  Abstract  
submitted by kickingbird at May, 17, 2025 from Antibodies. 2025; 14(2):42 (via https://www.mdpi.com/2073-4468/14/2/42)
Background/Objetives: Nanobodies (VHH) have become an excellent tool for diagnosis, therapy, and research since VHH shows a high capability of recognizing and neutralizing antigens. VHHs are highly soluble ...

Bonilla-Aldana DK, Bonilla-Aldana JL, Acosta-Espa?. Highly Pathogenic Avian Influenza H5N1 in Cats (Felis catus): A Systematic Review and Meta-Analysis. Animals. 2025; 15(10):1441.  Abstract  
submitted by kickingbird at May, 17, 2025 from Animals. 2025; 15(10):1441 (via https://www.mdpi.com/2076-2615/15/10/1441)
Introduction: Highly pathogenic avian influenza (HPAI) H5N1, a zoonotic virus primarily affecting birds, has shown increasing cross-species transmission, including to domestic animals such as cats. Recent ...

Eggink Dirk, Kroneman Annelies, Dingemans Jozef, G. Human infections with Eurasian avian-like swine influenza virus detected by coincidence via routine respiratory surveillance systems, the Netherlands, 2020 to 2023. Euro Surveill. 2025;30(19):pii=2400662.  Abstract  
submitted by kickingbird at May, 17, 2025 from Euro Surveill. 2025;30(19):pii=2400662 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Sporadic human infections with avian or swine influenza A virus (swIAV) have been reported. Zoonotic influenza, including human infections with avian influenza A virus or swIAV, is notifiable in the Netherlands ...

Ruchao Peng et al. Molecular basis of influenza ribonucleoprotein complex assembly and processive RNA synthesis. Science388,eadq7597(2025).  Abstract  
submitted by kickingbird at May, 16, 2025 from Science388,eadq7597(2025) (via https://www.science.org/doi/10.1126/science.adq7597)
INTRODUCTIONInfluenza virus poses a long-standing public health issue worldwide, causing both recurring seasonal flu and occasional pandemics in humans and other animals. Current vaccines and antivirals ...

Manman Dai, etc.,al. Chicken TCRγδ+CD8α+T cells are antigen-specific and protective in H9N2 AIV infection. The Journal of Immunology, vkaf083.  Abstract  
submitted by kickingbird at May, 16, 2025 from The Journal of Immunology, vkaf083 (via https://academic.oup.com/jimmunol/advance-article-abstract/d)
TCRγδ+ T cells are a major lymphocyte population of chickens, but their response or contribution to immunity against avian influenza virus (AIV) remains unknown. Here, we report an increase in the proportion ...

Stevenson-Leggett P, Adams L, Greenwood D, Lofts A. Investigation of Influenza A(H5N1) Virus Neutralization by Quadrivalent Seasonal Vaccines, United Kingdom, 2021–2024. Emerg Infect Dis. 2025 Jun.  Abstract  
submitted by kickingbird at May, 15, 2025 from Emerg Infect Dis. 2025 Jun (via https://wwwnc.cdc.gov/eid/article/31/6/24-1796_article)
We tested cross-neutralization against highly pathogenic avian influenza A(H5N1) virus in adults vaccinated with 2021–2023 seasonal quadrivalent influenza vaccine in the United Kingdom. Seasonal quadrivalent ...

Hassan M, Kaifer B, Christian T, Quaas XT, Mueller. First contact: an interdisciplinary guide into decoding H5N1 influenza virus interactions with glycosaminoglycans in 3D respiratory cell models. Front. Cell. Infect. Microbiol. 15:1596955.  Abstract  
submitted by kickingbird at May, 15, 2025 from Front. Cell. Infect. Microbiol. 15:1596955 (via https://www.frontiersin.org/journals/cellular-and-infection-)
The human respiratory system is vulnerable to viral infections. The influenza virus family alone accounts for one billion reported cases annually, some of which are severe and can be fatal. Among these, ...

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