Song X, Tian J, Li M, Bai X, Zhao Z, Shi J, Zeng X. Epidemiology and Biological Characteristics of Influenza A (H4N6) Viruses from Wild Birds. Emerg Microbes Infect. 2024 Oct 17:2418909. Abstract
submitted by kickingbird at Oct, 18, 2024 from Emerg Microbes Infect. 2024 Oct 17:2418909 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
During the active surveillance, we isolated nine H4N6 subtype influenza A viruses from wild birds in China. To reveal the epidemiology and biology characteristics of H4 subtype influenza A virus from wild ... Li F, Sun Z, Tao M, Song K, Wang Z, Ren X. Epidemiological characterization of human infection with H5N6 avian influenza. Front Public Health. 2024 Oct 2;12:1398365. Abstract
submitted by kickingbird at Oct, 18, 2024 from Front Public Health. 2024 Oct 2;12:1398365 (via https://www.frontiersin.org/journals/public-health/articles/)
Background: In recent years, there have been frequent reports of human infection with H5N6 avian influenza. However, the fundamental characteristics of the disease remain unclear. This paper conducts a ... Wille M, Broz I, Cherrington T, Crawley A, Farrugi. Contrasting dynamics of two incursions of low-pathogenicity avian influenza virus into Australia. Virus Evol. 2024 Sep 10;10(1):veae076. Abstract
submitted by kickingbird at Oct, 18, 2024 from Virus Evol. 2024 Sep 10;10(1):veae076 (via https://academic.oup.com/ve/article/10/1/veae076/7754475)
The current panzootic of high pathogenicity avian influenza virus H5N1 demonstrates how viral incursions can have major ramifications for wildlife and domestic animals. Herein, we describe the recent incursion ... Gross J, Volmer R, Bessière P. High pathogenicity avian influenza virus emergence: Blame it on chickens or on humans raising chickens?. PLoS Pathog. 2024 Oct 16;20(10):e1012608. Abstract
submitted by kickingbird at Oct, 17, 2024 from PLoS Pathog. 2024 Oct 16;20(10):e1012608 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Low pathogenicity avian influenza viruses (LPAIV) of H5 and H7 subtypes can naturally evolve to replicate systemically in birds, acquiring a high pathogenicity avian influenza virus (HPAIV) phenotype. ... Michalska-Smith M, Clements E, Rasmussen E, Culhan. Location, Age, and Antibodies Predict Avian Influenza Virus Shedding in Ring-Billed and Franklin´s Gulls in Minnesota. Animals (Basel). 2024 Sep 26;14(19):2781. Abstract
submitted by kickingbird at Oct, 17, 2024 from Animals (Basel). 2024 Sep 26;14(19):2781 (via https://www.mdpi.com/2076-2615/14/19/2781)
Influenza A virus (IAV) is a multi-host pathogen maintained in water birds and capable of spillover into humans, wildlife, and livestock. Prior research has focused on dabbling ducks as a known IAV reservoir ... Martinez-Sobrido L, Nogales A. Recombinant Influenza A Viruses Expressing Reporter Genes from the Viral NS Segment. Int J Mol Sci. 2024 Oct 1;25(19):10584. Abstract
submitted by kickingbird at Oct, 17, 2024 from Int J Mol Sci. 2024 Oct 1;25(19):10584 (via https://www.mdpi.com/1422-0067/25/19/10584)
Studying influenza A viruses (IAVs) requires secondary experimental procedures to detect the presence of the virus in infected cells or animals. The ability to generate recombinant (r)IAV using reverse ... Baker AL, Arruda B, Palmer MV, Boggiatto P, Davila. Dairy cows inoculated with highly pathogenic avian influenza virus H5N1. Nature. 2024 Oct 15. Abstract
submitted by kickingbird at Oct, 17, 2024 from Nature. 2024 Oct 15 (via https://www.nature.com/articles/s41586-024-08166-6)
Highly pathogenic avian influenza (HPAI) H5N1 hemagglutinin clade 2.3.4.4b was detected in the United States in 2021. These HPAI viruses caused mortality events in poultry, wild birds, and wild mammals. ... Wang M, Gao Y, Shen C, Yang W, Peng Q, Cheng J, Sh. A human monoclonal antibody targeting the monomeric N6 neuraminidase confers protection against avian H5N6 influenza virus infection. Nat Commun. 2024 Oct 15;15(1):8871. Abstract
submitted by kickingbird at Oct, 15, 2024 from Nat Commun. 2024 Oct 15;15(1):8871 (via https://www.nature.com/articles/s41467-024-53301-6)
The influenza neuraminidase (NA) is a potential target for the development of a next-generation influenza vaccine, but its antigenicity is not well understood. Here, we isolate an anti-N6 human monoclonal ... Chiba S, Kiso M, Yamada S, Someya K, Onodera Y, Ya. An mRNA vaccine candidate encoding H5HA clade 2.3.4.4b protects mice from clade 2.3.2.1a virus infection. NPJ Vaccines. 2024 Oct 14;9(1):189. Abstract
submitted by kickingbird at Oct, 15, 2024 from NPJ Vaccines. 2024 Oct 14;9(1):189 (via https://www.nature.com/articles/s41541-024-00988-9)
Highly pathogenic avian influenza (HPAI) H5 viruses from different clades have been circulating globally, threatening wild/domestic birds and mammals. Given frequent spillovers and high mortality among ... Sobhy NM, Mu?oz AQ, Youssef CRB, Goyal SM. Comparative Inactivation of Three Different Subtypes of Avian Influenza Virus by Ozonized Water. Avian Dis. 2024 Sep;68(3):225-230.. Abstract
submitted by kickingbird at Oct, 15, 2024 from Avian Dis. 2024 Sep;68(3):225-230. (via https://bioone.org/journals/avian-diseases/volume-68/issue-3)
Avian influenza virus (AIV) causes frequent outbreaks in poultry with high morbidity and mortality. The virus can survive on different fomites, resulting in indirect transmission to susceptible hosts. ... Hsueh CS, Fasina O, Pi?eyro P, Ruden R, El-Gazzar. Histopathologic Features and Viral Antigen Distribution of H5N1 Highly Pathogenic Avian Influenza Virus Clade 2.3.4.4b from the 2022-2023 Outbreak in Iowa Wild Birds. Avian Dis. 2024 Sep;68(3):272-281. Abstract
submitted by kickingbird at Oct, 15, 2024 from Avian Dis. 2024 Sep;68(3):272-281 (via https://bioone.org/journals/avian-diseases/volume-68/issue-3)
In 2022, a new epornitic of H5N1 highly pathogenic avian influenza (HPAI) virus clade 2.3.4.4b emerged in U.S. domestic poultry with high prevalence in wild bird populations. We describe pathological findings ... WHO. Influenza at the human-animal interface summary and assessment, 27 September 2024. WHO. Abstract
submitted by kickingbird at Oct, 15, 2024 from WHO (via https://www.who.int/publications/m/item/influenza-at-the-hum)
From 20 July to 27 September 2024, the detection of influenza A(H5) virus in one human, influenza A(H5N1) in eight humans, influenza A(H9N2) virus in two humans, influenza A(H1N1) variant ((H1N1)v) virus ... Vatzia E, Paudyal B, Dema B, Carr BV, Sedaghat-Ros. Aerosol immunization with influenza matrix, nucleoprotein, or both prevents lung disease in pig. NPJ Vaccines. 2024 Oct 13;9(1):188. Abstract
submitted by kickingbird at Oct, 14, 2024 from NPJ Vaccines. 2024 Oct 13;9(1):188 (via https://www.nature.com/articles/s41541-024-00989-8)
Current influenza vaccines are strain-specific and require frequent updates to combat new strains, making a broadly protective influenza vaccine (BPIV) highly desirable. A promising strategy is to induce ... APHIS. Highly Pathogenic Avian Influenza H5N1 Genotype B3.13 in Dairy Cattle: National Epidemiologic Brief. USDA. Abstract
submitted by kickingbird at Oct, 14, 2024 from USDA (via https://www.aphis.usda.gov/sites/default/files/highly-pathog)
On March 25, 2024, USDA announced unpasteurized, clinical samples of milk from sick cattle collected from two dairy farms in Kansas and one in Texas, as well as an oropharyngeal swab from another dairy ... Qin Li, etc.,al. Thin-film freeze-drying of an influenza virus hemagglutinin mRNA vaccine in unilamellar lipid nanoparticles with blebs. Journal of Controlled Release. Abstract
submitted by kickingbird at Oct, 13, 2024 from Journal of Controlled Release (via https://www.sciencedirect.com/science/article/abs/pii/S01683)
Messenger RNA (mRNA) vaccines have revolutionized the fight against infectious diseases and are poised to transform other therapeutic areas. Lipid nanoparticles (LNP) represent the most successful delivery ... Marcus Tong Zhen Wei, etc.,al. High glycaemic variability is associated with a reduced T cell cytokine response to influenza A virus. iScience. Abstract
submitted by kickingbird at Oct, 13, 2024 from iScience (via https://www.sciencedirect.com/science/article/pii/S258900422)
Diabetes mellitus significantly increases the risk of severe respiratory virus disease like influenza and COVID-19. Early evidence suggests that this susceptibility to respiratory viral disease is driven ... Tian Y, Lu X, Xiao D, Zhou C.. Long-Lasting Chemiluminescence Based on Functionalized Multicolor Protein Capsules for Multiple Visualization Detection of Avian Influenza Virus Biomarkers. Anal Chem. 2024 Oct 11. Abstract
submitted by kickingbird at Oct, 12, 2024 from Anal Chem. 2024 Oct 11 (via https://pubs.acs.org/doi/10.1021/acs.analchem.4c04248)
Long-lasting chemiluminescence (CL) emissions are necessary for improving the detection accuracy and expanding the application scope. Here, we have synthesized three oil-in-water (O/W) multicolor protein ... Joseph D. Trimarco, etc.,al. Fluorescent and bioluminescent bovine H5N1 influenza viruses for evaluation of antiviral interventions. Virology，10 Oct 2024. Abstract
submitted by kickingbird at Oct, 12, 2024 from Virology，10 Oct 2024 (via https://journals.asm.org/doi/10.1128/jvi.01385-24)
In early 2024, a clade 2.3.4.4b high pathogenic H5N1 avian influenza virus was detected in dairy cows and humans in the United States. Since then, it has spread to herds in at least 13 states and caused ... María Ríos Carrasco, Andrea Gr?ne, Judith M. A. v. The mammary glands of cows abundantly display receptors for circulating avian H5 viruses. Virology， 10 Oct 2024. Abstract
submitted by kickingbird at Oct, 11, 2024 from Virology， 10 Oct 2024 (via https://journals.asm.org/doi/10.1128/jvi.01052-24)
Influenza A viruses (IAVs) from the H5N1 2.3.4.4b clade are circulating in dairy farms in the USA.; ruminants were presumed not to be hosts for IAVs. Previously, IAV-positive mammalian species were hunters ... Jarek Juraszek, etc.,al. Engineering a cleaved, prefusion-stabilized influenza B virus hemagglutinin by identification and locking of all six pH-switches. PNAS Nexus. Abstract
submitted by kickingbird at Oct, 11, 2024 from PNAS Nexus (via https://academic.oup.com/pnasnexus/advance-article/doi/10.10)
Vaccine components based on viral fusion proteins require high stability of the native prefusion conformation for optimal potency and manufacturability. In the case of influenza B virus hemagglutinin (HA), ... 9542 items, 20/Page, Page[76/478][|<<] [|<] [71] [72] [73] [74] [75] [76] [77] [78] [79] [80] [>|] [>>|] |
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