Sharabrin SV, Krasnikova SI, Kisakov DN, Borgoyako. A Naked Lyophilized mRNA Vaccine Against Seasonal Influenza, Administered by Jet Injection, Provides a Robust Response in Immunized Mice. Vaccines. 2026; 14(1):56. Abstract
submitted by kickingbird at Jan, 2, 2026 from Vaccines. 2026; 14(1):56 (via https://www.mdpi.com/2076-393X/14/1/56)
Background: Seasonal influenza remains a significant public health problem, and the constant antigenic drift of viruses requires regular vaccine updates. mRNA vaccines offer a promising platform for the ... Luo Y, Dong M, Shen Y, Xiang X, Lv J, Sun Y, Li Y,. Impact of viral Ribonucleoprotein Complex Genetic Stability on Pathogenicity in H9N2 and H6N2 Avian Influenza Viruses. Dev Comp Immunol. 2025 Dec 27:105544. Abstract
submitted by kickingbird at Dec, 31, 2025 from Dev Comp Immunol. 2025 Dec 27:105544 (via https://www.sciencedirect.com/science/article/abs/pii/S01453)
China has a great demand for poultry, while avian influenza (AI) remains widespread and exhibits high instability, posing a persistent challenge to the poultry industry. Elucidating the genetic stability ... Rai, Kul Raj et al.. The long non-coding RNA MALAT1 encodes a micropeptide that promotes influenza A virus replication by suppressing innate immune responses. Journal of Biological Chemistry. Abstract
submitted by kickingbird at Dec, 31, 2025 from Journal of Biological Chemistry (via https://www.jbc.org/article/S0021-9258(25)02964-3/fulltext)
Long non-coding RNAs (lncRNAs) play critical roles in diverse biological processes and contain structurally distinct domains enabling multifunctional activity. Viral infections dynamically regulate lncRNA ... Wu, Y., Li, M., Li, H. et al. Cryo-EM structure of influenza polymerase bound to the cRNA promoter provides insights into the mechanism of viral replication. Commun Biol (2025). Abstract
submitted by kickingbird at Dec, 31, 2025 from Commun Biol (2025) (via https://www.nature.com/articles/s42003-025-09384-y)
Influenza virus polymerase (FluPol) synthesizes the complementary RNA (cRNA) and the viral RNA (vRNA) using distinct de novo initiation strategies during genome replication, known as internal and terminal ... Veldhuis Kroeze, E.J.B., Bellido Martin, B., Mols,. Pathology and virology of natural high pathogenicity avian influenza A(H5N1) Gs/GD genotype BB virus infection in wild black-headed gulls (Chroicocephalus ridibundus). Vet Res. 2025 Dec 29;56(1):234. Abstract
submitted by kickingbird at Dec, 31, 2025 from Vet Res. 2025 Dec 29;56(1):234 (via https://link.springer.com/article/10.1186/s13567-025-01666-x)
The ongoing worldwide outbreak of high pathogenicity avian influenza (HPAI) H5 of the Goose/Guangdong (Gs/GD) lineage has caused unprecedented mortality amongst an ever-expanding number of avian and mammalian ... Ward, J., Lambert, J.W., Russell, T.W. et al. Estimates of epidemiological parameters for H5N1 influenza in humans: a rapid review. BMC Infect Dis 25, 1755 (2025). Abstract
submitted by kickingbird at Dec, 31, 2025 from BMC Infect Dis 25, 1755 (2025) (via https://link.springer.com/article/10.1186/s12879-025-11933-z)
Background: The ongoing H5N1 panzootic in mammals has amplified zoonotic pathways to facilitate human infection. Characterising key epidemiological parameters for H5N1 is critical should it become widespread.Aim: ... Peng J, Miao X, Zhang X, Li Z, Wang Y, Liu G, Na L. Molecular Characterization of an H3N2 Canine Influenza Virus Isolated from a Dog in Jiangsu, China, in 2025. Veterinary Sciences. 2026; 13(1):32. Abstract
submitted by kickingbird at Dec, 31, 2025 from Veterinary Sciences. 2026; 13(1):32 (via https://www.mdpi.com/2306-7381/13/1/32)
To investigate the molecular characteristics of H3N2 canine influenza viruses circulating in Jiangsu, China, we isolated a H3N2 strain (A/Canine/Nanjing/CnNj01-2025) from a dog presenting with respiratory ... Gazik NH, Holodniy M, Bayat V. Expanding Horizons: Host Range Evolution and Treatment Strategies for Highly Pathogenic Avian Influenza H5N1 and H7N9. Viruses. 2026; 18(1):54. Abstract
submitted by kickingbird at Dec, 31, 2025 from Viruses. 2026; 18(1):54 (via https://www.mdpi.com/1999-4915/18/1/54)
Avian influenza viruses (AIVs), including H5N1 and H7N9, from the Orthomyxoviridae family present substantial public health concerns. The predominant circulating clade 2.3.4.4b has demonstrated enhanced ... Alekseev A, Sobolev I, Sharshov K, Gulyaeva M, Kur. Pathobiology of Highly Pathogenic Avian Influenza A (H5N1 Clade 2.3.4.4b) Virus from Pinnipeds on Tyuleniy Island in the Sea of Okhotsk, Russia. Viruses. 2026; 18(1):51. Abstract
submitted by kickingbird at Dec, 31, 2025 from Viruses. 2026; 18(1):51 (via https://www.mdpi.com/1999-4915/18/1/51)
Highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b has recently emerged as a major threat to wildlife, agriculture, and public health due to its expanding host range and the increasing frequency ... Adams GC, Devlin JE, Klontz E, Laing RA, Branda JA. Development of a Combined Clinical and Research-Developed Testing Strategy for Highly Pathogenic Avian Influenza A Virus H5. Open Forum Infect Dis. 2025 Dec 10;13(1):ofaf744. Abstract
submitted by kickingbird at Dec, 30, 2025 from Open Forum Infect Dis. 2025 Dec 10;13(1):ofaf744 (via https://academic.oup.com/ofid/article/13/1/ofaf744/8376911)
Highly pathogenic avian influenza A (H5) virus continues to spread in animals with ongoing concern for potential human transmission. We describe an adaptable H5 screening approach that integrates clinical ... Avkan I, Gokool S, Smith LE, Clapp G, Cox R, Thoma. Quantifying H5N1 outbreak potential and control effectiveness in high-risk agricultural populations. PLOS Glob Public Health. 2025 Dec 29;5(12):e000546. Abstract
submitted by kickingbird at Dec, 30, 2025 from PLOS Glob Public Health. 2025 Dec 29;5(12):e000546 (via https://journals.plos.org/globalpublichealth/article?id=10.1)
Avian influenza is a global public health threat. Since 2021, the ongoing H5N1 panzootic has brought a major shift in H5Nx epidemiology, including unprecedented spread, wide host range and lack of seasonality. ... Tian C, Feng L, Zhou X, Huang K, Wang F, Luo R, Me. A Portable One-Tube Assay Integrating RT-RPA and CRISPR/Cas12a for Rapid Visual Detection of Eurasian Avian-like H1N1 Swine Influenza Virus in the Field. Viruses. 2026; 18(1):47. Abstract
submitted by kickingbird at Dec, 29, 2025 from Viruses. 2026; 18(1):47 (via https://www.mdpi.com/1999-4915/18/1/47)
The widespread circulation of Eurasian avian-like H1N1 (EA H1N1) swine influenza virus poses significant zoonotic and pandemic risks worldwide. However, current diagnostic methods are difficult to deploy ... Yuwen Luo, etc.,al. Impact of viral Ribonucleoprotein Complex Genetic Stability on Pathogenicity in H9N2 and H6N2 Avian Influenza Viruses. Developmental & Comparative Immunology. Abstract
submitted by kickingbird at Dec, 28, 2025 from Developmental & Comparative Immunology (via https://www.sciencedirect.com/science/article/abs/pii/S01453)
China has a great demand for poultry, while avian influenza (AI) remains widespread and exhibits high instability, posing a persistent challenge to the poultry industry. Elucidating the genetic stability ... Harrell T.L., Shwani A., Suarez D.L. The Impact of Acids, pH, and Incubation Time on Avian Influenza Virus Persistence in Raw Milk. Food Microbiology. Abstract
submitted by kickingbird at Dec, 28, 2025 from Food Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S07400)
In March 2024, highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4.b H5N1 was detected in dairy cattle. Since detection, the virus has spread across 17 states, infecting more than 1000 dairy ... Ane Marie Anderson, etc.,al. DNA vaccines targeting hemagglutinin from 18 subtypes of influenza A virus to antigen presenting cells confer broad protection. Molecular Therapy Nucleic Acids. Abstract
submitted by kickingbird at Dec, 28, 2025 from Molecular Therapy Nucleic Acids (via https://www.sciencedirect.com/science/article/pii/S216225312)
Novel vaccines that confer broad protection against influenza A viruses (IAV) are urgently needed. Hemagglutinin (HA) is the major influenza antigen targeted by protective immune responses. We have here ... Zhu, T., Zhu, M., Lu, F. et al. Pre-activation timing determines influenza severity and viral pathogenicity via STING Inhibition. Sci Rep 15, 44501 (2025). Abstract
submitted by kickingbird at Dec, 28, 2025 from Sci Rep 15, 44501 (2025) (via https://www.nature.com/articles/s41598-025-28063-w)
Severe influenza is frequently associated with bacterial or viral co-infections. Although immune-mediated mechanisms have been extensively investigated, the cell-intrinsic responses of respiratory epithelial ... Yang G, Chen P-L, Rovito SW, Minari K, Writt HN, D. Resistance Mutations to Broadly Neutralizing Antibodies Destabilize Hemagglutinin and Attenuate H1N1 Influenza Virus. Viruses. 2026; 18(1):32. Abstract
submitted by kickingbird at Dec, 25, 2025 from Viruses. 2026; 18(1):32 (via https://www.mdpi.com/1999-4915/18/1/32)
Because antigenic drift primarily generates amino-acid changes in the membrane-distal hemagglutinin (HA) head, broadly neutralizing antibodies (bNAbs) are being developed to target conserved epitopes in ... Panova, A.S., Gudymo, A.S., Kolosova, N.P. et al. Genotype A3 influenza A(H5N1) isolated from fur seals shows high virulence in mammals, but not airborne transmission. Sci Rep 15, 44463 (2025). Abstract
submitted by kickingbird at Dec, 25, 2025 from Sci Rep 15, 44463 (2025) (via https://link.springer.com/article/10.1038/s41598-025-28032-3)
The global spread of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b viruses has recently extended to include diverse mammalian species, raising new concerns about pandemic risk. In 2023, this ... Mengdi Guan, etc.,al. Genetic diversity of H13 avian influenza viruses in migratory shorebirds in eastern China. Journal of Integrative Agriculture. Abstract
submitted by kickingbird at Dec, 25, 2025 from Journal of Integrative Agriculture (via https://www.sciencedirect.com/science/article/pii/S209531192)
Highlights1.Twenty one H13 subtype avian influenza viruses were isolated from 50016 samples in migratory birds during 2017 to 2024 in Shandong Province, China2.The H13 viruses were mainly harbored by shorebirds ... Epidemic and Pandemic Preparedness and Prevention. Stockpiling of medical countermeasures for pandemic influenza: considerations brief. WHO. Abstract
submitted by kickingbird at Dec, 24, 2025 from WHO (via https://www.who.int/publications/i/item/9789240117860)
This document provides a comprehensive, risk-informed framework to support countries in assessing, designing, and managing medical countermeasure (MCM) stockpiles for pandemic influenza and related respiratory ... 9775 items, 20/Page, Page[7/489][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
Related Pages:
Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!
|
- 
