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2026-2-1 18:35:24
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Wang J, Xiong Y, Li B, Yang J, Xiao D, Fu X, Long. A 14-year influenza reinfection surveillance in Chongqing, China: A retrospective analysis. Hum Vaccin Immunother. 2025 Dec;21(1):2497576.  Abstract  
submitted by kickingbird at May, 6, 2025 from Hum Vaccin Immunother. 2025 Dec;21(1):2497576 (via https://www.tandfonline.com/doi/full/10.1080/21645515.2025.2)
Influenza poses a significant medical burden and has the potential to cause global pandemics. To better understand the epidemiological characteristics of influenza reinfections and identify factors associated ...

Zhang X, Yang Y, Han X, Wei D, Niu B, Huang Q, Li. Unique Phenomenon of H5 Highly Pathogenic Avian Influenza Virus in China: Co-circulation of Clade 2.3.4.4b H5N1 and H5N6 results in diversity of H5 Virus. Emerg Microbes Infect. 2025 May 6:2502005.  Abstract  
submitted by kickingbird at May, 6, 2025 from Emerg Microbes Infect. 2025 May 6:2502005 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Recently, Clade 2.3.4.4b H5N1 virus has been widely prevalent globally. Although no outbreaks of Avian Influenza have occurred in poultry in China recently, Clade 2.3.4.4b H5 virus can still be isolated ...

Song, JH., Son, SE., Kim, HW. et al. Intranasally administered whole virion inactivated vaccine against clade 2.3.4.4b H5N1 influenza virus with optimized antigen and increased cross-protection. Virol J 22, 131 (2025).  Abstract  
submitted by kickingbird at May, 6, 2025 from Virol J 22, 131 (2025) (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
The global spread, frequent antigenic changes, and pandemic potential of clade 2.3.4.4b highly pathogenic avian influenza H5N1 underscore the urgent need for robust cross-protective vaccines. Here, we ...

Yasuhisa Fujita, Marwa Akao, Daiki Tatematsu, etc.. [preprint]Modeling viral shedding and symptom outcomes in oseltamivir-treated experimental influenza infection. https://doi.org/10.1101/2025.05.02.651873.  Abstract  
submitted by kickingbird at May, 6, 2025 from https://doi.org/10.1101/2025.05.02.651873 (via https://www.biorxiv.org/content/10.1101/2025.05.02.651873v1)
Influenza remains a global public health concern, and although the antiviral drug oseltamivir is widely used to treat infections, questions regarding its actual antiviral efficacy and clinical benefits ...

Van Borm S, Ahrens AK, Bachofen C, Banyard AC, Arn. Genesis and Spread of Novel Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Genotype EA-2023-DG Reassortant, Western Europe. Emerg Infect Dis. 2025 Jun.  Abstract  
submitted by kickingbird at May, 6, 2025 from Emerg Infect Dis. 2025 Jun (via https://wwwnc.cdc.gov/eid/article/31/6/24-1870_article)
In Europe, highly pathogenic avian influenza (HPAI) virus circulates in avian wildlife, undergoing frequent reassortment, sporadic introductions in domestic birds, and spillover to mammals. An H5N1 clade ...

Cecilia Di Genova, etc.,al. [preprint]Pigeons exhibit low susceptibility and poor transmission capacity for H5N1 clade 2.3.4.4b high pathogenicity avian influenza virus. https://doi.org/10.1101/2025.05.02.651910.  Abstract  
submitted by kickingbird at May, 4, 2025 from https://doi.org/10.1101/2025.05.02.651910 (via https://www.biorxiv.org/content/10.1101/2025.05.02.651910v1)
The ongoing panzootic of H5N1 high pathogenicity avian influenza virus (HPAIV) has caused the deaths of over half a billion wild birds and poultry, and has led to spillover events in both wild and domestic ...

Emi Takashita, etc.,al. Impact of the Polymerase Acidic Protein E199K Substitution in Influenza A Viruses on Baloxavir Susceptibility. Antiviral Research 2025.  Abstract  
submitted by kickingbird at May, 4, 2025 from Antiviral Research 2025 (via https://www.sciencedirect.com/science/article/pii/S016635422)
Baloxavir marboxil, a cap-dependent endonuclease inhibitor, was approved in Japan in 2018 for the treatment and prophylaxis of influenza. Its active form, baloxavir acid, binds to the polymerase acidic ...

Clément Fage, etc.,al. Influenza A(H1N1)pdm09 Virus Resistance to Baloxavir, Oseltamivir and Sialic Acid Mimetics in Single and Dual therapies: Insights from Human Airway Epithelia and Murine Models. Antiviral Research 2025.  Abstract  
submitted by kickingbird at May, 4, 2025 from Antiviral Research 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S01663)
Influenza viruses pose a significant threat due to annual epidemics and pandemic potential. Resistance to current antivirals underscores the need for new drugs and strategies to prevent its emergence. ...

Heinz Feldmann, etc.,al. [preprint]Bovine Derived Clade 2.3.4.4b HPAI H5N1 Virus Causes Mild Disease and Limited Transmission in Pigs. https://doi.org/10.21203/rs.3.rs-6567595/v1.  Abstract  
submitted by kickingbird at May, 3, 2025 from https://doi.org/10.21203/rs.3.rs-6567595/v1 (via https://www.researchsquare.com/article/rs-6567595/v1)
Highly pathogenic avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b emerged in dairy cows in the United States in early 2024. Since then, this clade simultaneously circulates in wild birds, cattle and ...

Carine K. Souza, etc.,al. [preprint]H5 influenza virus mRNA-lipid nanoparticle (LNP) vaccination elicits adaptive immune responses in Holstein calves. https://doi.org/10.1101/2025.05.01.651548.  Abstract  
submitted by kickingbird at May, 3, 2025 from https://doi.org/10.1101/2025.05.01.651548 (via https://www.biorxiv.org/content/10.1101/2025.05.01.651548v2)
Highly pathogenic avian influenza (HPAI) clade 2.3.4.4b H5N1 is circulating widely in lactating cows in the United States. Due to the critical need for intervention strategies for this outbreak, we evaluated ...

USCDC. Influenza Risk Assessment Tool (IRAT) Virus Descriptions and Report Summaries-H5N1. IRAT.  Abstract  
submitted by kickingbird at May, 3, 2025 from IRAT (via https://www.cdc.gov/pandemic-flu/php/monitoring/virus-descri)
On May 2, 2025, CDC published a new IRAT assessment for two clade 2.3.4.4b avian influenza A(H5N1) viruses: A/California/147/2024 and A/Washington/239/2024. These are two viruses that caused recent human ...

Brock N, Pulit-Penaloza JA, Belser JA, Pappas C, S. Avian Influenza A(H5N1) Isolated from Dairy Farm Worker, Michigan. Emerg Infect Dis. 2025 June.  Abstract  
submitted by kickingbird at May, 3, 2025 from Emerg Infect Dis. 2025 June (via https://wwwnc.cdc.gov/eid/article/31/6/25-0386_article)
Influenza A(H5N1) viruses have been detected in US dairy cow herds since 2024. We assessed the pathogenesis, transmission, and airborne release of A/Michigan/90/2024, an H5N1 isolate from a dairy farm ...

Benjamin C Mollett, etc.,al. [preprint]Diverse Genomic Landscape of Swine Influenza A Virus in England (2014 ~ 2021). https://doi.org/10.1101/2025.04.28.650978.  Abstract  
submitted by kickingbird at May, 2, 2025 from https://doi.org/10.1101/2025.04.28.650978 (via https://www.biorxiv.org/content/10.1101/2025.04.28.650978v1)
Surveillance of influenza A viruses in pigs (SwIAV) is critical for identification of novel genetic groups that pose a risk to pig health and might have zoonotic potential. SwIAVs circulating in pigs in ...

Er JC. Improving Influenza Nomenclature Based on Transmission Dynamics. Viruses. 2025; 17(5):633.  Abstract  
submitted by kickingbird at May, 1, 2025 from Viruses. 2025; 17(5):633 (via https://www.mdpi.com/1999-4915/17/5/633)
Influenza A viruses (IAVs) evolve rapidly, exhibit zoonotic potential, and frequently adapt to new hosts, often establishing long-term reservoirs. Despite advancements in genetic sequencing and phylogenetic ...

Ruiz S, Díaz-Gavidia C, González MA, Galdames P, O. Circulation and Spillover of pdmH1N1 Influenza A Virus at an Educational Swine Farm in Chile, 2019–2023. Viruses 2025; 17, no. 5: 635.  Abstract  
submitted by kickingbird at May, 1, 2025 from Viruses 2025; 17, no. 5: 635 (via https://www.mdpi.com/1999-4915/17/5/635)
Educational farms provide students with hands-on experience in agricultural and animal practices. However, the close contact between humans and farm animals creates a significant interface for zoonotic ...

Perera, T., Bowatte, A., Perera, S. et al. Molecular and phylogenetic analysis of influenza A and B viruses circulating in Sri Lanka following the COVID-19 pandemic. Virus Genes (2025).  Abstract  
submitted by kickingbird at May, 1, 2025 from Virus Genes (2025) (via https://link.springer.com/article/10.1007/s11262-025-02161-3)
Influenza viruses pose significant public health challenges, causing seasonal epidemics with high morbidity and mortality. This study sequenced influenza viral RNA from hospitalized patients with severe ...

McDuie F, T Overton C, A Lorenz A, L Matchett E, L. Mitigating Risk: Predicting H5N1 Avian Influenza Spread with an Empirical Model of Bird Movement. Transbound Emerg Dis. 2024 Jul 18;2024:5525298.  Abstract  
submitted by kickingbird at May, 1, 2025 from Transbound Emerg Dis. 2024 Jul 18;2024:5525298 (via https://onlinelibrary.wiley.com/doi/10.1155/2024/5525298)
Understanding timing and distribution of virus spread is critical to global commercial and wildlife biosecurity management. A highly pathogenic avian influenza virus (HPAIv) global panzootic, affecting ...

Gorin S, Richard G, Quéguiner S, Chastagner A, Bar. Pathogenesis, Transmission, and Within-Host Evolution of Bovine-Origin Influenza D Virus in Pigs. Transbound Emerg Dis. 2024 May 14;2024:9009051.  Abstract  
submitted by kickingbird at May, 1, 2025 from Transbound Emerg Dis. 2024 May 14;2024:9009051 (via https://onlinelibrary.wiley.com/doi/10.1155/2024/9009051)
Whereas bovine has been demonstrated as the main reservoir of influenza D virus (IDV), this virus was first isolated in a pig and is regularly detected in some swine populations. However, the role of swine ...

Harrington WN, Turner JCM, Barman S, Feeroz MM, Ha. Longitudinal Active Avian Influenza Surveillance in Bangladesh From 2017-2022 Reveals Differential IAV and H5 Infection and Viral Burden Associated With Bird Species, Sex, and Age. Transbound Emerg Dis. 2024 Dec 13;2024:5569836.  Abstract  
submitted by kickingbird at May, 1, 2025 from Transbound Emerg Dis. 2024 Dec 13;2024:5569836 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/5569836)
Influenza viruses are a major global health burden with up to 650,000 associated deaths annually. Beyond seasonal illness, influenza A viruses (IAVs) pose a constant pandemic threat due to novel emergent ...

Goraichuk IV, Suarez DL. Custom barcoded primers for influenza A nanopore sequencing: enhanced performance with reduced preparation time. Front. Cell. Infect. Microbiol. 15:1545032.  Abstract  
submitted by kickingbird at May, 1, 2025 from Front. Cell. Infect. Microbiol. 15:1545032 (via https://www.frontiersin.org/journals/cellular-and-infection-)
Highly pathogenic avian influenza is endemic and widespread in wild birds and is causing major outbreaks in poultry worldwide and in U.S. dairy cows, with several recent human cases, highlighting the need ...

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