Yunfei Wang, Fabiola Vacca, Wes Rountree, Kevin Wi. [preprint]Characterization of Influenza A HA and NA Subtypes Using Protein Sequences. https://doi.org/10.64898/2026.07.22.740123. Abstract
submitted by kickingbird at Jul, 29, 2026 from https://doi.org/10.64898/2026.07.22.740123 (via https://www.biorxiv.org/content/10.64898/2026.07.22.740123v1)
Motivation Influenza is an infectious disease associated with excess human deaths. For influenza A virus (IAV), the surface antigens hemagglutinin (HA) and neuraminidase (NA) define the specific subtype. ... Laura Mojsiejczuk, etc.,al. [preprint]Flu Mutation Explorer: an Interactive Platform for Mapping Host Adaptation Mutations in Influenza A Viruses. https://doi.org/10.64898/2026.07.22.740012. Abstract
submitted by kickingbird at Jul, 29, 2026 from https://doi.org/10.64898/2026.07.22.740012 (via https://www.biorxiv.org/content/10.64898/2026.07.22.740012v1)
A rapid expansion of influenza A virus (IAV) genome sequencing has transformed global surveillance but has also created major challenges for interpreting the biological significance of viral mutations, ... Lara S. U. Schwab, etc.,al. [preprint]Epistasis facilitates the long-term antigenic evolution of the influenza B virus hemagglutinin. https://doi.org/10.64898/2026.07.22.739994. Abstract
submitted by kickingbird at Jul, 29, 2026 from https://doi.org/10.64898/2026.07.22.739994 (via https://www.biorxiv.org/content/10.64898/2026.07.22.739994v1)
The antigenic drift of viral glycoproteins must be balanced by purifying selection pressure to maintain functionality. Understanding these evolutionary processes is key to predicting and combating viral ... Ji J, Lin Y, Zhu Z, Yue K, Zhang Y, Zhang W, Lei B. Immunoinformatics Design of a Broad-Spectrum Multi-Epitope Vaccine Targeting HA2 and M1 of H9N2 AIV. Microorganisms. 2026; 14(8):1617. Abstract
submitted by kickingbird at Jul, 29, 2026 from Microorganisms. 2026; 14(8):1617 (via https://www.mdpi.com/2076-2607/14/8/1617)
H9N2 avian influenza virus (AIV) continues to mutate, leading to immunosuppression and secondary infections in poultry. Traditional inactivated vaccines mainly induce humoral immunity and have limited ... Thayse Bruggemann, etc.,al. Phospholipid Phosphatase 6 (PLPP6) protects against influenza A virus infection in mice. The Journal of Immunology. Abstract
submitted by kickingbird at Jul, 29, 2026 from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/Supplement_1/v)
IntroductionPhospholipid phosphatase 6 (PLPP6) is a membrane-associated enzyme that regulates polyisoprenoid diphosphate signaling in cell activation. In response to inflammatory stimuli, PLPP6 converts ... Sean A Nelson, etc.,al. Distinct kinetic features of innate and adaptive responses in influenza A versus influenza B–infected mice. The Journal of Immunology. Abstract
submitted by kickingbird at Jul, 29, 2026 from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/7/vkag196/8745)
Influenza B infection is an important source of morbidity and mortality, especially in vulnerable populations such as children. Improved vaccines and antiviral therapeutics are hindered by gaps in knowledge ... Guo Luo, Emmanuel Mignot, Jing Zhang. Immunity to influenza B and cross-reactivity to Pandemrix/pH1N1 in narcolepsy. The Journal of Immunology. Abstract
submitted by kickingbird at Jul, 29, 2026 from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/Supplement_1/v)
IntroductionNarcolepsy type 1 (NT1) is caused by 85-95% hypocretin (HCRT) neuron loss due to a combination of genetic and environmental risk factors and associated with DQA1*01:02/DQB1*06:02 (DQ0602, 98%) ... Amber Smith, etc.,al. Multivariate Host-Pathogen Interactions Driving Heterogeneous Response to Influenza. The Journal of Immunology. Abstract
submitted by kickingbird at Jul, 29, 2026 from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/Supplement_1/v)
IntroductionInfluenza infections differ greatly among individuals, with controlled human infection studies showing wide variation in viral load, immune activation, and symptom profiles. However, the biological ... Rafael Medina, etc.,al. Dysregulated host responses are associated with severe influenza A virus disease in individuals with arterial hypertension. The Journal of Immunology. Abstract
submitted by kickingbird at Jul, 29, 2026 from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/Supplement_1/v)
IntroductionInfluenza A virus (IV) infections cause seasonal epidemics, which remain a major cause of morbidity and mortality worldwide. Disease severity depends on virological and host factors including ... Raymond Ash, etc.,al. Contribution of Influenza H5 Head and Stalk Domains to the Development of Functional Non-Neutralizing Antibodies Following Mucosal rH5-NE Vaccination. The Journal of Immunology. Abstract
submitted by kickingbird at Jul, 29, 2026 from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/Supplement_1/v)
IntroductionIn a prior Phase 1 trial we showed that an intranasal (IN) recombinant hemagglutinin (HA) H5 vaccine (rH5; A/Indo/05) nanoemulsion-adjuvanted (rH5 NE) and given on days 1 and 29 effectively ... Shiteng Huang, etc.,al. Molecular epidemiological characteristics of H9N2 subtype avian influenza virus in the external environment of Western Zhejiang, China, 2014-2025. Front. Public Health. Abstract
submitted by kickingbird at Jul, 29, 2026 from Front. Public Health (via https://www.frontiersin.org/journals/public-health/articles/)
Objective: To elucidate the epidemiological distribution patterns of avian influenza virus (AIV) in the external environment of western Zhejiang from 2014 to 2025, analyze the molecular epidemiological ... Bemis IG, Shittu I, Gomez JF, Fadaka EA, Perez S,. Seroprevalence of Influenza A(H5N1) Virus in Domestic Cats at Epicenter of Dairy Cattle Outbreaks, California, USA, 2024–2026. Emerg Infect Dis. 2026 Sep. Abstract
submitted by kickingbird at Jul, 29, 2026 from Emerg Infect Dis. 2026 Sep (via https://wwwnc.cdc.gov/eid/article/32/9/26-0785_article)
We conducted a serologic study of domestic cats near the epicenter of the dairy cattle outbreaks of influenza A(H5N1) in California, USA. Three of the 12 cats sampled within 2 km of farms had neutralizing ... Zelmar Rodriguez, etc.,al. Long-term milk-yield impact and recovery in HPAI-affected cows across consecutive lactations and its association with antibody response. Journal of Dairy Science. Abstract
submitted by kickingbird at Jul, 28, 2026 from Journal of Dairy Science (via https://www.sciencedirect.com/science/article/pii/S002203022)
This cohort study quantifies the long-term impact of HPAI H5N1 on cumulative milk yield and milk-yield trajectories during the affected lactation, and carryover effects in the subsequent lactation; and ... Fritsch, H., Arora, P., Yan, M., Grotha, I., Pfarr. Beyond H5N1: influenza A virus infection in bovine udder organoids. Emerging Microbes & Infections, 15(1). Abstract
submitted by kickingbird at Jul, 28, 2026 from Emerging Microbes & Infections, 15(1) (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Influenza A viruses (IAVs) have recently expanded their host range to bovine species, raising critical questions about tissue tropism, viral replication capacity, and impacts on dairy production and zoonotic ... Lee, H., Shin, Y., Heo, J. Y., Yu, A., Park, J. H.. Porcine Airway Organoids Reveal Strain-Associated Replication and Epithelial Host Response Signatures of a Reassortant H1N1 Virus. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Jul, 28, 2026 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Pigs serve as mixing vessels for influenza A viruses, facilitating reassortment and the emergence of variants with zoonotic potential. Since the 2009 pandemic, human-origin influenza gene segments have ... Liu B, Li F, Yang Y, Tu H, Hao P, Ma Q, Le Y, Zhan. In-depth monitoring of host cell proteins in influenza vaccines throughout multi-step purification processes. Vaccine. 2026 Jul 25;88:128957. Abstract
submitted by kickingbird at Jul, 27, 2026 from Vaccine. 2026 Jul 25;88:128957 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Influenza viruses, characterized by antigenic drift and shift, can cause seasonal epidemics or pandemics. According to World Health Organization (WHO) data, approximately 650,000 global annual deaths are ... Hu, T., Lupton, L.L., Yehoshua, A. et al. The Impact of Influenza on Health-Related Quality of Life, Work Productivity, and Activity Impairment Among Symptomatic US Patients with Influenza. Infect Dis Ther (2026). Abstract
submitted by kickingbird at Jul, 26, 2026 from Infect Dis Ther (2026) (via https://link.springer.com/article/10.1007/s40121-026-01407-3)
Introduction: Evidence on the impact of influenza on health-related quality of life (HRQoL) and work productivity and activity impairment (WPAI) remains limited. This study evaluated changes in the EuroQol ... Ma C, Xu Z. An Interpretable Decomposition-Based Framework for U.S. Influenza-like Illness Surveillance. Stats. 2026; 9(4):78. Abstract
submitted by kickingbird at Jul, 26, 2026 from Stats. 2026; 9(4):78 (via https://www.mdpi.com/2571-905X/9/4/78)
Public-health respiratory-disease surveillance requires distinguishing expected seasonal illness activity from atypical changes that may warrant further investigation. Weekly influenza-like illness (ILI) ... Li, X., Lv, X., Li, Y. et al. Evolving dynamics of H5Nx avian influenza in China revealed by long-term wild bird surveillance. Nat Commun (2026). Abstract
submitted by kickingbird at Jul, 26, 2026 from Nat Commun (2026) (via https://link.springer.com/article/10.1038/s41467-026-76039-9)
H5Nx highly pathogenic avian influenza viruses pose persistent threats to poultry, wildlife, and public health. Over the past two decades, their geographic and host ranges have expanded across migratory ... Liu, X., Jin, J., Xu, Z. et al. Effectiveness of seasonal influenza vaccine against dominant A(H1N1)pdm09 in adults≧60 years: a multicenter test-negative design in Zhejiang, China, 2024~2025. BMC Geriatr (2026). Abstract
submitted by kickingbird at Jul, 26, 2026 from BMC Geriatr (2026) (via https://link.springer.com/article/10.1186/s12877-026-08049-7)
BackgroundZhejiang Province, China, has implemented a free influenza vaccination program for the elderly population for five consecutive years. However, data on real-world vaccine effectiveness against ... 10582 items, 20/Page, Page[5/530][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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