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2026-3-18 9:07:23
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Charlotte Kristiane Hjulsager, Yuan Liang, Casper. Mass mortalities caused by different genotypes of HPAIV H5N1 clade 2.3.4.4b in colony breeding Black-headed Gulls and Sandwich Terns in Denmark 2022 and 2023. Canadian Journal of Microbiology, Vol 72, 2026.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Canadian Journal of Microbiology, Vol 72, 2026 (via https://www.sciencedirect.com/org/science/article/pii/S00084)
Unprecedented seabird mass mortality events (MMEs) were reported in multiple European countries in 2022 and 2023. These events were attributed to Clade 2.3.4.4b H5N1 high pathogenicity avian influenza ...

Susannah Gold, Bart Donato, Vivienne Booth. Evaluating the effectiveness of carcass removal to mitigate highly pathogenic avian influenza outbreaks in ground-nesting bird colonies: A modelling approach. Ecological Solutions and Evidence, 7, e70185.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Ecological Solutions and Evidence, 7, e70185 (via https://besjournals.onlinelibrary.wiley.com/doi/10.1002/2688)
Since 2020, impacts of highly pathogenic avian influenza (HPAI) on wild bird populations have escalated globally. Colonial nesting birds are particularly vulnerable, as high-density colonies facilitate ...

Steinfurth, A., Lynton-Jenkins, J. G., Cleeland, J. Investigating high pathogenicity avian influenza virus incursions to remote islands: detection of H5N1 on Gough Island in the South Atlantic Ocean. Emerging Microbes & Infections, 15(1).  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Emerging Microbes & Infections, 15(1) (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Understanding the mechanisms underlying the emergence and spread of high pathogenicity avian influenza virus (HPAIV) is critical for tracking its global dissemination, particularly via migratory seabirds, ...

Son DH, Balupuri A, Nam JH, Kim IH, Choi YJ, An BM. Analyses of receptor binding specificity of highly pathogenic avian influenza a (H5N1) viruses isolated from felines in South Korea, 2023. Virulence. 2026 Feb 23:2636350.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Virulence. 2026 Feb 23:2636350 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2026.2)
Influenza viruses infect host cells by binding to specific sialic acid receptors present on the surface of target cells, and this receptor binding exhibits specificity depending on cell type and host species. ...

Kikawa C, Loes AN, Huddleston J, Figgins MD, Stein. High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains. Elife. 2026 Feb 23;14:RP106811.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Elife. 2026 Feb 23;14:RP106811 (via https://elifesciences.org/articles/106811)
Human influenza viruses rapidly acquire mutations in their hemagglutinin (HA) protein that erode neutralization by antibodies from prior exposures. Here, we use a sequencing-based assay to measure neutralization ...

Miller J, Diefenbach-Elstob T, Wordsworth R, Deshp. Report on influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza during 2024. Commun Dis Intell (2018). 2026 Feb 24;50.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Commun Dis Intell (2018). 2026 Feb 24;50 (via https://ojs.cdi.cdc.gov.au/index.php/cdi/article/view/3449)
As part of its role in the World Health Organization (WHO) Global Influenza Surveillance and Response System (GISRS), the WHO Collaborating Centre for Reference and Research on Influenza in Melbourne received ...

Caroline Kikawa, etc.,al. [preprint]Near real-time data on the human neutralizing antibody landscape to influenza virus as of early 2026 to inform vaccine-strain selection. https://doi.org/10.64898/2026.02.18.706711.  Abstract  
submitted by kickingbird at Feb, 23, 2026 from https://doi.org/10.64898/2026.02.18.706711 (via https://www.biorxiv.org/content/10.64898/2026.02.18.706711v1)
Twice each year, a decision is made on whether to update the strains included in the seasonal influenza vaccine to better match the most recent circulating viral strains. To characterize the antigenic ...

Liping Wang, etc.,al. [preprint]Vaccine-Elicited Antibody Responses to Influenza H3N2 Subclade K. https://doi.org/10.64898/2026.02.02.26345378.  Abstract  
submitted by kickingbird at Feb, 23, 2026 from https://doi.org/10.64898/2026.02.02.26345378 (via https://www.medrxiv.org/content/10.64898/2026.02.02.26345378)
Influenza H3N2 subclade K (J.2.4.1) is a genetic branch of H3N2 with 11 mutations in hemagglutinin and currently represents the dominant circulating influenza strain. We evaluated antibody responses to ...

Adria Wilson, etc.,al. [preprint]Seasonal vaccine-induced immunity shows preserved cross-reactivity to H3N2 subclade K in adults. https://doi.org/10.64898/2026.02.18.26346502.  Abstract  
submitted by kickingbird at Feb, 23, 2026 from https://doi.org/10.64898/2026.02.18.26346502 (via https://www.medrxiv.org/content/10.64898/2026.02.18.26346502)
Influenza A subclade K viruses caused high infection rates in the 2025/2026 Northern Hemisphere season, raising concerns about antigenic drift and reduced vaccine effectiveness. We measured antibody responses ...

Jiaojiao Liu, etc.,al. [preprint]Mapping the specificity of H3N2 strain-specific and cross-reactive human neutralizing antibodies elicited by the 2025-2026 influenza vaccine. https://doi.org/10.64898/2026.02.20.26346746.  Abstract  
submitted by kickingbird at Feb, 23, 2026 from https://doi.org/10.64898/2026.02.20.26346746 (via https://www.medrxiv.org/content/10.64898/2026.02.20.26346746)
An H3N2 variant, named subclade K, continues to circulate widely during the 2025-2026 influenza season. This virus possesses a hemagglutinin (HA) protein that has eleven substitutions relative to the HA ...

George S. Long, etc.,al. [preprint]Genomic, antigenic and transmission dynamics of influenza A(H3N2) subclade K in Canada, early 2025/26 season. https://doi.org/10.64898/2026.02.10.26345998.  Abstract  
submitted by kickingbird at Feb, 23, 2026 from https://doi.org/10.64898/2026.02.10.26345998 (via https://www.medrxiv.org/content/10.64898/2026.02.10.26345998)
Influenza A(H3N2) subclade K virus was detected in Canada early in the 2025/26 influenza season, bearing an antigenic transition in the hemagglutinin (HA) glycoprotein. Analysis of 396 HA sequences from ...

Salman L. Butt, etc.,al. [preprint]Hematogenous neuroinvasion and genotype-dependent transmission of influenza A H5N1 viruses in the cat host. https://doi.org/10.64898/2026.02.21.707182.  Abstract  
submitted by kickingbird at Feb, 23, 2026 from https://doi.org/10.64898/2026.02.21.707182 (via https://www.biorxiv.org/content/10.64898/2026.02.21.707182v1)
The spillover of highly pathogenic avian influenza (HPAI) A H5N1 virus to mammalian hosts raises major concerns due to its pandemic potential. Cats are frequently affected mammals, often succumbing to ...

Naveed, A. The bovine mammary gland as a crucible for zoonotic influenza virus emergence: Receptor-mediated adaptation of HPAI H5N1 clade 2.3.4.4b. Arch Virol 171, 89 (2026).  Abstract  
submitted by kickingbird at Feb, 23, 2026 from Arch Virol 171, 89 (2026) (via https://link.springer.com/article/10.1007/s00705-026-06529-0)
The recent emergence of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b in U.S. dairy cattle marks a pivotal shift in the ecology of influenza A viruses (IAVs), signaling an unexpected expansion ...

WHO/WPRO. Avian Influenza Weekly Update # 1034: 20 February 2026. WHO.  Abstract  
submitted by kickingbird at Feb, 23, 2026 from WHO (via https://www.who.int/westernpacific/publications/m/item/avian)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ...

Katherine J. Koebel, etc.,al. [prepint]Quantitative microbial risk assessment of human H5N1 infection from consumption of fluid cow’s milk. https://doi.org/10.1101/2024.12.20.24319470.  Abstract  
submitted by kickingbird at Feb, 22, 2026 from https://doi.org/10.1101/2024.12.20.24319470 (via https://www.medrxiv.org/content/10.1101/2024.12.20.24319470v)
The spillover of H5N1 clade 2.3.4.4b into dairy cattle has raised concerns over the safety of fluid milk. While no foodborne infection has been reported in humans, this strain has infected at least 70 ...

Pan X, Shi X, Zhao L, Yan D, Zhou F, Liu Q, Yuan C. Amino acid mutations K54E and S154P in the neuraminidase attenuate H3N2 canine influenza virus in mice. J Gen Virol. 2026 Feb;107(2).  Abstract  
submitted by kickingbird at Feb, 22, 2026 from J Gen Virol. 2026 Feb;107(2) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Dogs are considered mixing vessels for influenza viruses, posing a pandemic potential via viral reassortment. Our previous studies indicated that the avian-origin H3N2 canine influenza virus (A/canine/Zhejiang/1/2010, ...

Couture A, Biggerstaff M, Sheppard M, Budd A, Kite. Spatiotemporal transmission of influenza in the US during the 2022/23 season. Epidemics. 2026 Feb 14;54:100896.  Abstract  
submitted by kickingbird at Feb, 22, 2026 from Epidemics. 2026 Feb 14;54:100896 (via https://www.sciencedirect.com/science/article/pii/S175543652)
Understanding the spatiotemporal dynamics of seasonal influenza spread across the United States (US) is crucial for informed public health planning. We explored patterns of influenza transmission during ...

Poliakiwski BD, Minela T, Smith DJ, Seekford ZK, C. Spatial localization of avian and human influenza A virus receptors in male and female bovine reproductive tissues. Sci Rep. 2026 Feb 20.  Abstract  
submitted by kickingbird at Feb, 22, 2026 from Sci Rep. 2026 Feb 20 (via https://www.nature.com/articles/s41598-026-36120-1)
Highly pathogenic avian influenza virus (HPAIV) of the H5N1 type has recently emerged as a major concern in livestock, with widespread outbreaks now confirmed in U.S. dairy cattle. This raises critical ...

Wang P, Li L, Chen Y, Tong L, Li Z, Yu R, Shen Q,. Attenuation of Influenza A Virus into Live Vaccines Through C-End Degrons. Adv Sci (Weinh). 2026 Feb 21:e09425.  Abstract  
submitted by kickingbird at Feb, 22, 2026 from Adv Sci (Weinh). 2026 Feb 21:e09425 (via https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.20)
Harnessing the cell's ubiquitin-proteasome system (UPS) to manipulate viral protein degradation represents a promising way to develop live attenuated vaccines. We previously developed a proteolysis-targeting ...

Shosha EAE, Mohamd MK, Shehata MAE, Mohamed MH, El. Genomic and evolutionary characterization of newly emerged highly pathogenic avian influenza H5N1 clade (2023-2025). Veterinary World, 18(12): 3745–3760.  Abstract  
submitted by kickingbird at Feb, 21, 2026 from Veterinary World, 18(12): 3745–3760 (via https://veterinaryworld.org/Vol.18/December-2025/6.php)
Background and aim: Highly pathogenic avian influenza virus (HPAI) H5N1 continues to threaten poultry biosecurity worldwide due to rapid antigenic drift and reassortment. Since late 2020, clade 2.3.4.4b ...

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