WPRO. Avian Influenza Weekly Update # 1000: 6 June 2025. WHO. Abstract
submitted by kickingbird at Jun, 9, 2025 from WHO (via https://cdn.who.int/media/docs/default-source/wpro---documen)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ... Gao, J., Landgraf, G., Yuan, Y. et al. Influenza neuraminidase active site proximity assay for rapid profiling of inhibitory antibodies and antigenic drift. npj Vaccines 10, 118 (2025). Abstract
submitted by kickingbird at Jun, 8, 2025 from npj Vaccines 10, 118 (2025) (via https://www.nature.com/articles/s41541-025-01173-2)
Efficient approaches that can help to select vaccine strains for the influenza virus neuraminidase (NA) antigen are currently needed to advance the development of vaccines containing NA. Here, we present ... Amalie B. Rasmussen, etc.,al. [preprint]Influenza A virus polymerase co-opts distinct sets of host proteins for RNA transcription or replication. https://doi.org/10.1101/2025.06.06.658254. Abstract
submitted by kickingbird at Jun, 8, 2025 from https://doi.org/10.1101/2025.06.06.658254 (via https://www.biorxiv.org/content/10.1101/2025.06.06.658254v1)
The influenza A virus polymerase, consisting of a heterotrimer of three viral proteins, carries out both transcription and replication of the viral RNA genome. These distinct activities are regulated by ... Sayan Das, etc.,al. [preprint]Enhancing protective efficacy and immunogenicity of hemagglutinin-based influenza vaccine utilizing adjuvants developed by BECC. https://doi.org/10.1101/2025.06.03.657703. Abstract
submitted by kickingbird at Jun, 8, 2025 from https://doi.org/10.1101/2025.06.03.657703 (via https://www.biorxiv.org/content/10.1101/2025.06.03.657703v1)
Seasonal influenza viruses continue to pose a significant threat, causing substantial morbidity and mortality in the US and worldwide despite the availability of vaccines and antivirals. These challenges ... Ou J, Dai Y, Jiang Y, Dai L, Xu L, Lu G, Lou G, Li. Identification of the functional domains of canine tetherin in antiviral activity against canine influenza virus. Front Vet Sci. 2025 May 21;12:1560273. Abstract
submitted by kickingbird at Jun, 6, 2025 from Front Vet Sci. 2025 May 21;12:1560273 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Canine influenza virus (CIV) is a respiratory pathogen that causes fever, coughing, and sneezing in dogs and is continuously circulating in canine populations. Tetherin is an antiviral host restriction ... Kaitlyn Sarlo Davila, etc.,al. [preprint]Susceptibility of calves fed unpasteurized milk from cows experimentally infected with highly pathogenic avian influenza H5N1. https://doi.org/10.21203/rs.3.rs-6681893/v1. Abstract
submitted by kickingbird at Jun, 6, 2025 from https://doi.org/10.21203/rs.3.rs-6681893/v1 (via https://www.researchsquare.com/article/rs-6681893/v1)
Highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b genotype B3.13 was confirmed in a dairy cow in Texas on March 25, 2024, by the US Department of Agriculture (USDA) National Veterinary Services ... van der Vries Erhard, Germeraad Evelien A, Kronema. Swine influenza virus surveillance programme pilot to assess the risk for animal and public health, the Netherlands, 2022 to 2023. Euro Surveill. 2025;30(22):pii=2400664. Abstract
submitted by kickingbird at Jun, 6, 2025 from Euro Surveill. 2025;30(22):pii=2400664 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Swine influenza A viruses (swIAV) are enzootic in pigs in Europe and cause respiratory disease in pigs. Clinical signs include fever, coughing, nasal discharge, sneezing, laboured breathing and loss of ... Madison T. Gouthro, Emalie K. Hayes, Taylor Prest,. [preprint]Detection of Avian Influenza Virus in Surface Waters Using Passive Samplers. https://doi.org/10.21203/rs.3.rs-6768892/v1. Abstract
submitted by kickingbird at Jun, 6, 2025 from https://doi.org/10.21203/rs.3.rs-6768892/v1 (via https://www.researchsquare.com/article/rs-6768892/v1)
Avian influenza (AIV) remains a global concern not only for humans as a pandemic threat but pose a risk to poultry, wildlife, and livestock. The presence of AIV in the environment traditionally has relied ... Kim, DH., Lee, DY., Seo, Y. et al. Immediate PB2-E627K amino acid substitution after single infection of highly pathogenic avian influenza H5N1 clade 2.3.4.4b in mice. Virol J 22, 183 (2025). Abstract
submitted by kickingbird at Jun, 5, 2025 from Virol J 22, 183 (2025) (via https://link.springer.com/article/10.1186/s12985-025-02811-w)
The highly pathogenic avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b has rapidly disseminated globally, with mammalian infections reported in multiple species. Recent evidence of mammal-to-mammal transmission ... Capelastegui F, Goldhill DH. H5N1 2.3.4.4b: a review of mammalian adaptations and risk of pandemic emergence. J Gen Virol. 2025 Jun;106(6). Abstract
submitted by kickingbird at Jun, 5, 2025 from J Gen Virol. 2025 Jun;106(6) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Avian influenza viruses can cause severe disease when they spill over into mammalian and human hosts. H5N1 clade 2.3.4.4b has spread globally since 2021, decimating avian species, and has spilled over ... Coggon A, Lopes S, Simon G, Arendsee Z, Chen K-F,. Quantifying the zoonotic risk profile of European influenza A viruses in swine from 2010 to 2020 inclusive. J Virol. 2025 Jun 4:e0030625. Abstract
submitted by kickingbird at Jun, 5, 2025 from J Virol. 2025 Jun 4:e0030625 (via https://journals.asm.org/doi/10.1128/jvi.00306-25)
H1 and H3 influenza A viruses (IAVs) circulating in European pigs are markedly distinct from those circulating in other global swine populations. These viruses exhibit significant genetic diversity, further ... Singh G, Kafle S, Assato P, Goraya M, Morozov I, R. Single-Cell Analysis of Host Responses in Bovine Milk Somatic Cells (bMSCs) Following HPAIV Bovine H5N1 Influenza Exposure. Viruses. 2025; 17(6):811. Abstract
submitted by kickingbird at Jun, 5, 2025 from Viruses. 2025; 17(6):811 (via https://www.mdpi.com/1999-4915/17/6/811)
The 2024 outbreak of highly pathogenic avian influenza virus (HPAIV) H5N1 in U.S. dairy cattle presented an unprecedented scenario where the virus infected bovine mammary glands and was detected in milk, ... Vitale R, Denina M, Badiali L, Sandei M, Mazzetti. Influenza-Related Encephalopathy in Children: Epidemiology and Literature Review from a Tertiary Hospital in Northern Italy (Winter 2023–2024). Pathogens. 2025; 14(6):551. Abstract
submitted by kickingbird at Jun, 5, 2025 from Pathogens. 2025; 14(6):551 (via https://www.mdpi.com/2076-0817/14/6/551)
Introduction: While influenza-associated encephalopathy (IAE) in children remains a serious concern, recent evidence suggests a shift in its epidemiology, with a possible decline in incidence and severity ... Peng W, Liu H, Wang X, Li C, Huang S, Qi S, Hu Z,. Analysis of Epidemiological and Evolutionary Characteristics of Seasonal Influenza Viruses in Shenzhen City from 2018 to 2024. Viruses. 2025; 17(6):798. Abstract
submitted by kickingbird at Jun, 5, 2025 from Viruses. 2025; 17(6):798 (via https://www.mdpi.com/1999-4915/17/6/798)
The SARS-CoV-2 pandemic and the implementation of associated non-pharmaceutical interventions (NPIs) profoundly altered the epidemiology of seasonal influenza viruses. To investigate these changes, we ... Li Y, Quan X, Chen R, Wang X, Chen Y, Gan Y, Irwin. Adaptive selection of quasispecies during in vivo passaging in chickens, mice, and ferrets results in host-specific strains for the H9N2 avian influenza virus. J Virol 0:e00151-25. Abstract
submitted by kickingbird at Jun, 5, 2025 from J Virol 0:e00151-25 (via https://journals.asm.org/doi/10.1128/jvi.00151-25)
Sporadic human infections of avian influenza virus (AIV) raise significant public health concerns. A critical factor limiting the transmission of AIVs is the shift in receptor-binding preference from Siaα2,3 ... Bingkuan Zhu, etc.,al. [preprint]The hemagglutinin proteins of clades 1 and 2.3.4.4b H5N1 highly pathogenic avian influenza viruses exhibit comparable attachment patterns to avian and mammalian tissues. https://doi.org/10.1101/2025.06.02.657404. Abstract
submitted by kickingbird at Jun, 5, 2025 from https://doi.org/10.1101/2025.06.02.657404 (via https://www.biorxiv.org/content/10.1101/2025.06.02.657404v1)
The global spread of the A/goose/Guangdong/1/96-lineage H5N1 highly pathogenic avian influenza (HPAI) viruses is accompanied by an expanded host range and the establishment of sustained viral transmission ... Robinson-McCarthy LR, Zirckel KE, Simmons HC, Le S. A replicating recombinant vesicular stomatitis virus model for dairy cattle H5N1 influenza virus glycoprotein evolution. J Virol 0:e00389-25. Abstract
submitted by kickingbird at Jun, 5, 2025 from J Virol 0:e00389-25 (via https://journals.asm.org/doi/10.1128/jvi.00389-25)
A panzootic of highly pathogenic avian influenza (HPAI) H5N1 viruses from clade 2.3.4.4b has triggered a multistate outbreak in US dairy cattle and an unknown number of human infections. HPAI viruses are ... Seibert B, Caceres CJ, Gay LC, Shetty N, Faccin FC. Air-liquid interface model for influenza aerosol exposure in vitro. J Virol. 2025 Jun 3:e0061925. Abstract
submitted by kickingbird at Jun, 4, 2025 from J Virol. 2025 Jun 3:e0061925 (via https://journals.asm.org/doi/10.1128/jvi.00619-25)
Airborne transmission is an essential mode of infection and spread of influenza viruses among humans. However, most studies use liquid inoculum for virus infection. To better replicate natural airborne ... Schlachter AD, Furman N, Byrne AMP, Reid SM, Smith. High pathogenicity avian influenza H5N1 clade 2.3.4.4b natural infection in captive Humboldt penguins (Spheniscus humboldti). Avian Pathol. 2025 Jun 3:1-21. Abstract
submitted by kickingbird at Jun, 4, 2025 from Avian Pathol. 2025 Jun 3:1-21 (via https://www.tandfonline.com/doi/full/10.1080/03079457.2025.2)
Between 2020 and 2023, high pathogenicity avian influenza virus (HPAIV) H5Nx clade 2.3.4.4b caused devastating outbreaks across Europe and the United Kingdom among domestic poultry and wild bird populations. ... Fabri ND, Santman-Berends IMGA, Roos CAJ, van Scha. No indication of highly pathogenic avian influenza infections in Dutch cows. JDS Commun. 2025 Mar 12;6(3):394-399. Abstract
submitted by kickingbird at Jun, 4, 2025 from JDS Commun. 2025 Mar 12;6(3):394-399 (via https://www.jdscommun.org/article/S2666-9102(25)00036-5/full)
In March 2024, an infection with highly pathogenic avian influenza (HPAI) virus subtype H5N1 of the HA clade 2.3.4.4b was detected in dairy cows in Texas. Following this first detection, the virus was ... 9775 items, 20/Page, Page[48/489][|<<] [|<] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [>|] [>>|] |
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