Between January 1 and August 4, 2025, 26 human infections with avian influenza A(H5N1) viruses (H5 bird flu) have been detected globally, of which 23 were identified in 7 countries outside of the United States, including 11 infections that resulted in death.
The three cases in the United States were previously reported, and there have been no cases reported in the United States since mid-February 2025.
The 11 deaths occurred in Cambodia (8), India (2), and Mexico (1). All of these infections were in people with likely or reported direct contact with poultry and/or wild birds.
No person-to-person spread was identified in any of these cases, and their occurrence is not thought to change the health risk to the U.S. public, which remains low at this time.
Due to widespread global outbreaks of H5N1 bird flu in wild birds and poultry, sporadic human infections with H5N1 virus are not surprising in persons with direct or close contact with sick or dead poultry or other infected animals, but they do underscore the importance of continued surveillance domestically and globally.