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2026-2-1 15:56:22
Article

Vasilev, K., Hoxie, I., Puente-Massaguer, E. et al. Immunogenicity and protective efficacy of an intranasal neuraminidase-based influenza vaccine with bacterial cell membrane-derived adjuvants. npj Vaccines 10, 149 (2025).  Abstract  
submitted by kickingbird at Jul, 14, 2025 from npj Vaccines 10, 149 (2025) (via https://link.springer.com/article/10.1038/s41541-025-01209-7)
Development of mucosal influenza virus vaccines which protect the site of viral entry is of high importance. Recombinant neuraminidase (NA) has emerged as an antigenically conserved intranasal vaccine ...

Nemoto, M., Kawanishi, N., Kambayashi, Y. et al. Growth properties of recombinant equine influenza viruses with different backbones generated by reverse genetics in embryonated chicken eggs. Arch Virol 170, 181 (2025).  Abstract  
submitted by kickingbird at Jul, 13, 2025 from Arch Virol 170, 181 (2025) (via https://link.springer.com/article/10.1007/s00705-025-06368-5)
Reverse genetics (RG) technology is useful for quickly updating influenza vaccine strains. A high-yield backbone (i.e., six segments other than hemagglutinin and neuraminidase) derived from A/Puerto Rico/8/1934 ...

Mostafa, A., Ye, C., Barre, R.S. et al. A live attenuated NS1-deficient vaccine candidate for cattle-origin influenza A (H5N1) clade 2.3.4.4.b viruses. npj Vaccines 10, 151 (2025).  Abstract  
submitted by kickingbird at Jul, 13, 2025 from npj Vaccines 10, 151 (2025) (via https://link.springer.com/article/10.1038/s41541-025-01207-9)
Avian Influenza viruses (AIVs) present a public health risk, especially with seasonal vaccines offering limited protection. AIV H5N1 clade 2.3.4.4b has caused a multi-state outbreaks in the United States ...

Cunningham MW, Brown J, Hardman R, Loerzel S, Klue. Outbreaks of Highly Pathogenic H5N1 Influenza A Virus infection in Black Vultures (Coragyps atratus), USA, 2022. J Wildl Dis. 2025 Jul 11.  Abstract  
submitted by kickingbird at Jul, 11, 2025 from J Wildl Dis. 2025 Jul 11 (via https://meridian.allenpress.com/jwd/article/doi/10.7589/JWD-)
Mortalities in Black Vultures (Coragyps atratus) caused by A/goose/Guangdong/1/1996 2.3.4.4b lineage highly pathogenic (HP) influenza A virus (IAV) H5N1 (HP H5N1) were detected in Florida, USA, on 14 February ...

Song Y, Zhang X, Ji J, Li L, Zhou Y, Ren G, Lv S,. Genetic characteristics analysis of influenza A(H1N1) virus in Jiaxing, China, in the postepidemic era. BMC Infect Dis. 2025 Jul 10;25(1):905.  Abstract  
submitted by kickingbird at Jul, 11, 2025 from BMC Infect Dis. 2025 Jul 10;25(1):905 (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
Background: Following the lifting of COVID-19 pandemic control measures, a progressive increase in influenza A virus activity, particularly the H1N1 subtype, has been observed in Jiaxing. This study systematically ...

Mosaad Z, Hagag NM, Elsayed MM, Mady WH, Zanaty AM. Isolation, characterization and phylogenetic analyses of avian influenza A (H9N2) viruses isolated from poultry between 2019 and 2023 in Egypt. BMC Vet Res. 2025 Jul 11;21(1):455.  Abstract  
submitted by kickingbird at Jul, 11, 2025 from BMC Vet Res. 2025 Jul 11;21(1):455 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
The current study aimed to investigate the genetic characterization and evolution of low pathogenic avian influenza virus H9N2 in Egypt. Ten H9N2 viruses were recently isolated from samples collected between ...

Neira V, Ariyama N, Castillo-Torres PN, Brito B, M. Genetic Characterization of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b, Antarctica, 2024. Emerg Infect Dis. 2025 Jul 9;31(8).  Abstract  
submitted by kickingbird at Jul, 11, 2025 from Emerg Infect Dis. 2025 Jul 9;31(8) (via https://wwwnc.cdc.gov/eid/article/31/8/25-0186_article)
In 2024, we sequenced highly pathogenic avian influenza virus A(H5N1) clade 2.3.4.4b genomes isolated from 5 brown skuas from James Ross Island, Antarctica. Phylogenetic analysis suggested the virus reached ...

Seo YR, Cho AY, Kim DJ, Si YJ, Jeong HS, Lee SW, S. Transmission Dynamics of Highly Pathogenic Avian Influenza A(H5N1) and A(H5N6) Viruses in Wild Birds, South Korea, 2023-2024. Emerg Infect Dis. 2025 Jul 9;37(8).  Abstract  
submitted by kickingbird at Jul, 11, 2025 from Emerg Infect Dis. 2025 Jul 9;37(8) (via https://wwwnc.cdc.gov/eid/article/31/8/25-0373_article)
We analyzed 15 cases of highly pathogenic avian influenza (HPAI) clade 2.3.4.4b virus infections detected in wild birds in South Korea during September 2023-March 2024. We isolated and sequenced 8 H5N1 ...

Biswas A, Eisfeld AJ, Guan L, Gu C, Wang T, Abozei. Susceptibility and shedding in Mx1+ and Mx1- female mice experimentally infected with dairy cattle A(H5N1) influenza viruses. EBioMedicine. 2025 Jul 8;118:105842.  Abstract  
submitted by kickingbird at Jul, 11, 2025 from EBioMedicine. 2025 Jul 8;118:105842 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: Clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) (HPAI H5N1) viruses have spread prolifically in dairy cattle in the US, resulting in dozens of human infections, some without well-established ...

Zhang T, Du J, Cao Y, Han H, Du Y, Hou Y, Du Q, So. Comparative study of rapid influenza antigen tests versus PCR in an influenza-like illness population: A real-world multicenter study in China. Infect Genet Evol. 2025 Jul 7:105794.  Abstract  
submitted by kickingbird at Jul, 11, 2025 from Infect Genet Evol. 2025 Jul 7:105794 (via https://www.sciencedirect.com/science/article/pii/S156713482)
This study aimed to explore the differences in detection between polymerase chain reaction (PCR) and rapid influenza antigen test (RIAT) in a population with influenza-like illness (ILI). A retrospective ...

Signore AV, Giacinti J, Jones MEB, Erdelyan CNG, M. Spatiotemporal reconstruction of the North American A(H5N1) outbreak reveals successive lineage replacements by descendant reassortants. Sci Adv. 2025 Jul 11;11(28):eadu4909.  Abstract  
submitted by kickingbird at Jul, 10, 2025 from Sci Adv. 2025 Jul 11;11(28):eadu4909 (via https://www.science.org/doi/10.1126/sciadv.adu4909)
The November 2021 introduction of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b into North America triggered a devastating outbreak, affecting more than 180 million domestic birds and spreading ...

Blaney K, Cardamone L, Clarke NE, Hayes MJ, Muleme. Responding to avian influenza in poultry farms in Victoria, Australia. Bull World Health Organ. 2025 Jul 1;103(7):437-444.  Abstract  
submitted by kickingbird at Jul, 10, 2025 from Bull World Health Organ. 2025 Jul 1;103(7):437-444 (via https://pmc.ncbi.nlm.nih.gov/articles/PMC12231074/)
Objective: To describe a multi-agency public response to an outbreak of avian influenza virus in poultry farms in Victoria, Australia, in 2024.Methods: After detecting an outbreak of high-pathogenicity ...

Kandel S, Babujee L, Guan L, Dahn R, Pattinson D,. Phylogenetic analysis of H5N1 influenza viruses isolated from dairy cattle in Texas in December 2024. J Virol. 2025 Jul 8:e0058025.  Abstract  
submitted by kickingbird at Jul, 9, 2025 from J Virol. 2025 Jul 8:e0058025 (via https://journals.asm.org/doi/10.1128/jvi.00580-25)
Highly pathogenic avian influenza (HPAI) viruses of genotype B3.13 were first reported in dairy cattle in March 2024 and, by 4 March 2025, had infected at least 989 cattle herds in 17 states in the US ...

Hao M, Wu J, Ji L, Zhao Y, Zhang S, Guan Y, Li L,. Pathogenicity, transmissibility, and receptor binding of a human-isolated influenza A (H10N5) virus. mBio. 2025 Jul 8:e0073125.  Abstract  
submitted by kickingbird at Jul, 9, 2025 from mBio. 2025 Jul 8:e0073125 (via https://journals.asm.org/doi/10.1128/mbio.00731-25)
Recently, human infections with H10 influenza viruses, including H10N8 and H10N3, have been reported. In January 2024, a case of H10N5 and H3N2 co-infection was reported in Zhejiang Province, China, which ...

Chen, T., Ouyang, A., Zou, J. et al. Rab27a regulates the transport of influenza virus membrane proteins to the plasma membrane. Nat Commun 16, 6271 (2025).  Abstract  
submitted by kickingbird at Jul, 9, 2025 from Nat Commun 16, 6271 (2025) (via https://www.nature.com/articles/s41467-025-61587-3)
The molecular mechanisms underlying the transport of influenza A virus (IAV) membrane proteins to the cell surface remain largely unclear. In this study, siRNA screening identifies Rab27a as a critical ...

Sanchez-Rojas IC, Bonilla-Aldana DK, Solarte-Jimen. Highly Pathogenic Avian Influenza (H5N1) Clade 2.3.4.4b in Cattle: A Rising One Health Concern. Animals. 2025; 15(13):1963.  Abstract  
submitted by kickingbird at Jul, 7, 2025 from Animals. 2025; 15(13):1963 (via https://www.mdpi.com/2076-2615/15/13/1963)
Highly pathogenic avian influenza (HPAI) H5N1, particularly clade 2.3.4.4b, has demonstrated an unprecedented capacity for cross-species transmission, with recent reports confirming its presence in dairy ...

Neil Paprocki, Jeff Kidd, Courtney J. Conway. Increased Mortality Rates Caused by Highly Pathogenic Avian Influenza Virus in a Migratory Raptor. Ecology and Evolution.  Abstract  
submitted by kickingbird at Jul, 7, 2025 from Ecology and Evolution (via https://onlinelibrary.wiley.com/doi/10.1002/ece3.71715)
Highly pathogenic avian influenza virus (HPAIV) has caused extensive mortalities in wild birds with a disproportionate impact on raptors since 2021. The population-level impact of HPAIV can be informed ...

Zhang, X., Wang, Y., Li, X. et al. Prevalence of Avian Influenza Viruses and Biomolecular Analysis of H9N2 Subtype in Live Poultry Markets from 2021 to 2023 in Changsha, China. Food Environ Virol 17, 38 (2025).  Abstract  
submitted by kickingbird at Jul, 7, 2025 from Food Environ Virol 17, 38 (2025) (via https://link.springer.com/article/10.1007/s12560-025-09652-4)
Environmental monitoring of avian influenza virus (AIV) in live poultry markets (LPMs) is vital for health risk forewarning, and survey of AIV environmental prevalence and biomolecular analysis of keystone ...

Kristen Coleman, etc.,al. [preprint]Highly Pathogenic Avian Influenza A(H5N1) Outbreak Among House Cats: A Case Series Involving Oseltamivir Treatment. https://doi.org/10.21203/rs.3.rs-7015836/v1.  Abstract  
submitted by kickingbird at Jul, 7, 2025 from https://doi.org/10.21203/rs.3.rs-7015836/v1 (via https://www.researchsquare.com/article/rs-7015836/v1)
We present a highly pathogenic avian influenza A(H5N1) outbreak among four domestic cats from the same household within close proximity to a dairy farm in Tulare, California – the epicenter of the H5N1 ...

Young-Jae Si, etc.,al. First Detection of Clade 2.3.4.4b H5N1 Highly Pathogenic Avian Influenza Virus in a Wild Leopard cat (Prionailurus bengalensis) in South Korea. Front. Vet. Sci..  Abstract  
submitted by kickingbird at Jul, 7, 2025 from Front. Vet. Sci. (via https://www.frontiersin.org/journals/veterinary-science/arti)
The A/goose/Guangdong/1/1996 (Gs/GD) lineage of highly pathogenic avian influenza (HPAI) viruses initially identified in China in 1996 and have evolved over subsequent decades, characterized by accumulation ...

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