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2026-2-1 12:53:42
Article

Beyit, A.D., Yahya, B., Ebou, M.H. et al. Detection and characterization of avian influenza H9N2 in a broiler farm in mauritania, 2024. Vet Res Commun 49, 272 (2025).  Abstract  
submitted by kickingbird at Aug, 7, 2025 from Vet Res Commun 49, 272 (2025) (via https://link.springer.com/article/10.1007/s11259-025-10847-0)
In October 2024, a broiler farm located south of Nouakchott, Mauritania, reported respiratory symptoms, diarrhoea, and 10% mortality within a flock of 4500 birds. Pooled organ samples (n?=?6) were collected ...

Liu Z, Zhang L, Zhang W, Lai Y, Deng T. The 5′-end segment-specific noncoding region of influenza A virus regulates both competitive multi-segment RNA transcription and selective genome packaging during infection. J Virol 0:e00328-25.  Abstract  
submitted by kickingbird at Aug, 7, 2025 from J Virol 0:e00328-25 (via https://journals.asm.org/doi/10.1128/jvi.00328-25)
The 3′ and 5′ termini of the eight RNA segments of the influenza A virus (IAV) genome contain segment-specific or subtype-specific (in HA and NA segments) noncoding regions (ssNCRs), located between the ...

Hammed Olawale Fatoyinbo, Parul Tiwari, Ryan H.L.. Multivariable analysis of highly pathogenic H5N1 and H5Nx avian influenza in wild birds and poultry in Asian subregions. Comparative Immunology, Microbiology and Infectiou.  Abstract  
submitted by kickingbird at Aug, 7, 2025 from Comparative Immunology, Microbiology and Infectiou (via https://www.sciencedirect.com/science/article/pii/S014795712)
The spread of highly pathogenic avian influenza (HPAI) virus in wild birds, poultry, and other livestock worldwide has caused great concerns, especially in Asia, where the migration routes of many wild ...

Mana Esaki, Kosuke Okuya, Kaori Tokorozaki, Yuko H. Surveillance of avian influenza viruses in the Izumi plain reveals the role of wild ducks in the introduction of H5N1 HPAIVs during the 2023/24 winter season. Comparative Immunology, Microbiology and Infectiou.  Abstract  
submitted by kickingbird at Aug, 7, 2025 from Comparative Immunology, Microbiology and Infectiou (via https://www.sciencedirect.com/science/article/abs/pii/S01479)
The Izumi plain, located in the southern part of Japan, serves as a major overwintering site for endangered crane species, including the hooded crane (Grus monacha) and the white-naped crane (Grus vipio). ...

Pengfei Wang, Linlin Yan, Jing Wang, Shoukui Hu, F. Utilizing multiplex reverse transcription-multiple cross displacement amplification-lateral flow biosensor technology for detecting H1N1, H3N2 and H7N9 influenza A virus subtypes. Journal of Virological Methods, Volume 338, 2025.  Abstract  
submitted by kickingbird at Aug, 7, 2025 from Journal of Virological Methods, Volume 338, 2025 (via https://www.sciencedirect.com/science/article/pii/S016609342)
Respiratory infections caused by influenza A viruses (IAVs) pose a global threat annually, leading to significant mortality in severe cases. IAVs are classified into various subtypes, and a combination ...

Sooksawasdi Na Ayudhya S, Leijten L, Rijnink WF, S. Attachment Patterns of Avian Influenza H5 Clade 2.3.4.4b Virus in Respiratory Tracts of Marine Mammals, North Atlantic Ocean. Emerg Infect Dis. 2025 Sep.  Abstract  
submitted by kickingbird at Aug, 7, 2025 from Emerg Infect Dis. 2025 Sep (via https://wwwnc.cdc.gov/eid/article/31/9/25-0499_article)
Highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus infections have caused substantial mortality events in marine mammals in recent years. We hypothesized that the high number of infections ...

L?chen A, Bonin B, Khoshabian R, Diep M, Iqbal S,. Identification of and Response to Influenza A(H5) in Off-the-Shelf Raw Milk-Santa Clara County, California, November-December 2024. Clin Infect Dis. 2025 Aug 4:ciaf420.  Abstract  
submitted by kickingbird at Aug, 6, 2025 from Clin Infect Dis. 2025 Aug 4:ciaf420 (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
In November-December 2024, the County of Santa Clara Public Health Department detected influenza A and A(H5) virus in unpasteurized milk sold in the county. A(H5N1) virus surveillance of off-the-shelf ...

Aslam S, Sánchez-Aparicio MT, Siempelkamp BD, Dorn. Influenza A virus NS1 protein mimics oncogenic PI3K resulting in isoform specific cellular redistribution and activation. Proc Natl Acad Sci U S A. 2025 Aug 12;122(32):e242.  Abstract  
submitted by kickingbird at Aug, 6, 2025 from Proc Natl Acad Sci U S A. 2025 Aug 12;122(32):e242 (via https://www.pnas.org/doi/10.1073/pnas.2423066122)
The nonstructural protein 1 (NS1) of influenza A virus performs a broad variety of proviral activities in the infected cell, primarily mediating evasion from the host innate immune response by being the ...

Cavicchio L, Tassoni L, Pastori A, Carrino M, Gagl. Swine influenza surveillance in Italy uncovers regional and farm-based genetic clustering. Front Microbiol. 2025 Jul 21;16:1607204.  Abstract  
submitted by kickingbird at Aug, 6, 2025 from Front Microbiol. 2025 Jul 21;16:1607204 (via https://www.frontiersin.org/journals/microbiology/articles/1)
Introduction: Swine Influenza is a respiratory disease endemic in pigs with implications for animal and public health. Pigs, as mixing vessels for human, avian, and swine influenza strains, contribute ...

Jumpei Ito, etc.,al. [preprint]Integrative modeling of seasonal influenza evolution via AI-powered antigenic cartography. https://doi.org/10.1101/2025.08.04.668423.  Abstract  
submitted by kickingbird at Aug, 6, 2025 from https://doi.org/10.1101/2025.08.04.668423 (via https://www.biorxiv.org/content/10.1101/2025.08.04.668423v1)
Seasonal influenza viruses evade host immunity through rapid antigenic evolution. Antigenicity is assessed by serological assays and typically visualized as antigenic maps, which represent antigenic differences ...

US CDC. Global Summary of Recent Human Cases of H5N1 Bird Flu. US CDC.  Abstract  
submitted by kickingbird at Aug, 6, 2025 from US CDC (via https://www.cdc.gov/bird-flu/spotlights/h5n1-summary-0804202)
Between January 1 and August 4, 2025, 26 human infections with avian influenza A(H5N1) viruses (H5 bird flu) have been detected globally, of which 23 were identified in 7 countries outside of the United ...

Chan JCM, Ching RHH, Kock HHM, Long T, Nicholls JM. Evaluation of pandemic potential of the genotype 4 (G4) swine influenza virus using ex vivo and in vitro cultures of the human respiratory tract. J Gen Virol. 2025 Jul;106(7):002133.  Abstract  
submitted by kickingbird at Aug, 4, 2025 from J Gen Virol. 2025 Jul;106(7):002133 (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Recent studies have reported a genotype 4 (G4) reassortant Eurasian avian-like (EA) H1N1 virus in swine, demonstrating a potential pandemic threat in humans. Here, we have compared the tropism, replication ...

Jo, G., Yamayoshi, S., Ma, K.M. et al. Structural basis of broad protection against influenza virus by human antibodies targeting the neuraminidase active site via a recurring motif in CDR H3. Nat Commun 16, 7067 (2025).  Abstract  
submitted by kickingbird at Aug, 3, 2025 from Nat Commun 16, 7067 (2025) (via https://link.springer.com/article/10.1038/s41467-025-62174-2)
Influenza viruses evolve rapidly, driving seasonal epidemics and posing global pandemic threats. While neuraminidase (NA) has emerged as a vaccine target, shared molecular features of NA antibody responses ...

Mansi Sharma, etc.,al. [preprint]Differential modulation of Interferon and Cell Death Responses defines Human vs Avian Influenza A Virus Strain-Specific Virulence and guides Combination Therapy. https://doi.org/10.1101/2025.07.31.667854.  Abstract  
submitted by kickingbird at Aug, 3, 2025 from https://doi.org/10.1101/2025.07.31.667854 (via https://www.biorxiv.org/content/10.1101/2025.07.31.667854v1)
Influenza A virus (IAV) poses a significant global health risk, with highly pathogenic strains like H5N1 (CFR ~52%) causing severe disease compared to less lethal but more transmissible strains like H1N1 ...

Mark A. Power, etc.,al. [preprint]Seasonal Influenza Exposure Elicits Functional Antibody and T-cell Responses to A(H5) Influenza Viruses in Humans. https://doi.org/10.1101/2025.07.31.25331995.  Abstract  
submitted by kickingbird at Aug, 3, 2025 from https://doi.org/10.1101/2025.07.31.25331995 (via https://www.medrxiv.org/content/10.1101/2025.07.31.25331995v)
Background Highly pathogenic avian influenza A(H5) viruses pose a pandemic threat, with a history of zoonotic spillovers into humans that are presumed immunologically na?ve. Whether the general population ...

Oluwatosin Babasola, Mohamed Bakheet, Christina Na. [preprint]A Phylogeny-Informed Mathematical Modeling of H5N1 Transmission Dynamics and Effectiveness of Control Measures. https://doi.org/10.1101/2025.07.29.25331913.  Abstract  
submitted by kickingbird at Aug, 3, 2025 from https://doi.org/10.1101/2025.07.29.25331913 (via https://www.medrxiv.org/content/10.1101/2025.07.29.25331913v)
The highly pathogenic avian influenza (HPAI) subtype H5N1 is a severe viral disease which continues to pose a significant threat to public health and a rigorous understanding of its transmission dynamics ...

Lv K, Li X, Zhu X, Cai JP, Liu S, Sun Y, Liu L, Ca. Broad neuraminidase antibodies confer protection against seasonal and avian influenza viruses. Nat Commun. 2025 Aug 2;16(1):7103.  Abstract  
submitted by kickingbird at Aug, 3, 2025 from Nat Commun. 2025 Aug 2;16(1):7103 (via https://www.nature.com/articles/s41467-025-62040-1)
Neuraminidase (NA) is a critical target for universal influenza vaccines and therapeutic antibodies, yet its antigenic landscape remains incompletely understood. Here we identify two broadly cross-protective ...

Kozawa F, Tamura T, Takahashi N, Kakizuka T, Ichim. The crucial role of intercellular calcium wave propagation triggered by influenza A virus in promoting infection. Cell Commun Signal. 2025 Aug 2;23(1):361.  Abstract  
submitted by kickingbird at Aug, 3, 2025 from Cell Commun Signal. 2025 Aug 2;23(1):361 (via https://biosignaling.biomedcentral.com/articles/10.1186/s129)
Background: Influenza A viruses (IAVs) initially infect a few host cells before spreading to neighboring cells. However, the molecular mechanisms underlying this dissemination remain unclear. We have previously ...

Lee HS, Noh JY, Cheong HJ. Influenza C virus in humans and animals. Clin Exp Vaccine Res. 2025 Jul;14(3):203-209.  Abstract  
submitted by kickingbird at Aug, 3, 2025 from Clin Exp Vaccine Res. 2025 Jul;14(3):203-209 (via https://ecevr.org/DOIx.php?id=10.7774/cevr.2025.14.e32)
Influenza C virus (ICV) was discovered in 1947 and detected in humans, with natural infections occurring periodically. However, early studies on ICV were challenging in diagnosis because the virus is difficult ...

Bayoumi M, Barre RS, Escobedo RA, Shivanna V, Jack. Identification of Amino Acid Residues in polymerase PB2 Responsible for Differential Replication and Pathogenicity of Avian Influenza Virus H5N1 Isolated from Human and Cattle in Texas, US. Emerg Microbes Infect. 2025 Aug 1:2542247.  Abstract  
submitted by kickingbird at Aug, 3, 2025 from Emerg Microbes Infect. 2025 Aug 1:2542247 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Highly pathogenic avian influenza viruses (HPAIV) pose a serious public health concern. In March 2024, a first-time outbreak of HPAIV H5N1 in dairy cattle herds was reported in the United States (US). ...

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