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Targonski PV, Jacobson RM, Poland GA. Immunosenescence: Role and measurement in influenza vaccine response among the elderly. Vaccine. 2007 Jan 16.  Abstract  
submitted by kickingbird at Feb, 15, 2007 from Vaccine. 2007 Jan 16 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Immunosenescence refers to the inability of an aging immune system to produce an appropriate and effective response to challenge. This immune dysfunction may manifest as increased susceptibility to infection, ...

Labadie K, Dos Santos Afonso E, Rameix-Welti MA, v. Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells. Virology. 2007 Jan 30.  Abstract  
submitted by kickingbird at Feb, 15, 2007 from Virology. 2007 Jan 30 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
The transcription/replication activity of ribonucleoproteins derived from influenza A primary isolates of human (A/Paris/908/97) or avian origin (A/Mallard/Marquenterre/MZ237/83, A/Hong Kong/156/97) was ...

Wong JP, Christopher ME, Salazar AM, Dale RM, Sun. Nucleic acid-based antiviral drugs against seasonal and avian influenza viruses. Vaccine. 2007 Jan 19;.  Abstract  
submitted by kickingbird at Feb, 15, 2007 from Vaccine. 2007 Jan 19; (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Influenza viruses are etiological agents of deadly flu that continue to pose global health threats, and have caused global pandemics that killed millions of people worldwide. The availability of neuraminidase ...

Satterly N, Tsai PL, van Deursen J, Nussenzveig DR. Influenza virus targets the mRNA export machinery and the nuclear pore complex. Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1853-8.  Abstract  
submitted by kickingbird at Feb, 15, 2007 from Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1853-8 (via http://www.pnas.org/cgi/content/full/104/6/1853)
The NS1 protein of influenza A virus is a major virulence factor that is essential for pathogenesis. NS1 functions to impair innate and adaptive immunity by inhibiting host signal transduction and gene ...

Humberd J, Boyd K, Webster RG. Emergence of Influenza A Virus Variants After Prolonged Shedding from Pheasants. J Virol. 2007 Jan 31.  Abstract  
submitted by kickingbird at Feb, 15, 2007 from J Virol. 2007 Jan 31 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
We previously demonstrated susceptibility of pheasants to infection with influenza A viruses of 15 HA subtypes: 13/23 viruses tested were isolated for >/=14 days, all in the presence of serum-neutralizing ...

de Jong JC, Smith DJ, Lapedes AS, Donatelli I, Cam. Antigenic and genetic evolution of swine influenza A(H3N2) viruses in Europe. J Virol. 2007 Feb 7.  Abstract  
submitted by kickingbird at Feb, 15, 2007 from J Virol. 2007 Feb 7 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
In the early 1970s a human influenza A/Port Chalmers/1/73 (H3N2)-like virus colonized the European swine population. Analyses of swine influenza A(H3N2) viruses isolated in the Netherlands and Belgium ...

Hashimoto Y, Moki T, Takizawa T, Shiratsuchi A, Na. Evidence for phagocytosis of influenza virus-infected, apoptotic cells by neutrophils and macrophages in mice. J Immunol. 2007 Feb 15;178(4):2448-57..  Abstract  
submitted by kickingbird at Feb, 15, 2007 from J Immunol. 2007 Feb 15;178(4):2448-57. (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Influenza virus-infected cells undergo apoptosis and become susceptible to phagocytosis by macrophages in vitro, and this leads to the propagation of the virus being inhibited. We previously showed that ...

Duerr HP, Schwehm M, Leary CC, De Vlas SJ, Eichner. The impact of contact structure on infectious disease control: influenza and antiviral agents. Epidemiol Infect. 2007 Feb 9;:1-9.  Abstract  
submitted by kickingbird at Feb, 15, 2007 from Epidemiol Infect. 2007 Feb 9;:1-9 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Planning adequate public health responses against emerging infectious diseases requires predictive tools to evaluate the impact of candidate intervention strategies. With current interest in pandemic influenza ...

Wang SQ, Du QS, Chou KC. Study of drug resistance of chicken influenza A virus (H5N1) from homology-modeled 3D structures of neuraminidases. Biochem Biophys Res Commun. 2007 Mar 16;354(3):634.  Abstract  
submitted by kickingbird at Feb, 15, 2007 from Biochem Biophys Res Commun. 2007 Mar 16;354(3):634 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
The spread of highly pathogenic H5N1 influenza virus in many Asian and European countries as well as its drug-resistance have raised serious worldwide concerns. In this paper, the structure-activity relationship ...

Sandbulte MR, Jimenez GS, Boon ACM, Smith LR, Tre. Cross-Reactive Neuraminidase Antibodies Afford Partial Protection against H5N1 in Mice and Are Present in Unexposed Humans. PLoS Medicine Vol. 4, No. 2, e59 doi:10.1371/journ.  Full Text  
submitted by kickingbird at Feb, 14, 2007 from PLoS Medicine Vol. 4, No. 2, e59 doi:10.1371/journ (via http://medicine.plosjournals.org/perlserv/?request=get-docum)
Background A pandemic H5N1 influenza outbreak would be facilitated by an absence of immunity to the avian-derived virus in the human population. Although this condition is likely in regard to hemagglutinin-mediated ...

Kung NY, Morris RS, Perkins NR, Sims LD, Ellis TM,. Risk for Infection with Highly Pathogenic Influenza A Virus (H5N1) in Chickens, Hong Kong, 2002. Emerg Infect Dis. 2007 Mar.  Abstract  
submitted by kickingbird at Feb, 13, 2007 from Emerg Infect Dis. 2007 Mar (via http://www.cdc.gov/eid/content/13/3/412.htm)
We used epidemiologic evaluation, molecular epidemiology, and a case-control study to identify possible risk factors for the spread of highly pathogenic avian influenza A virus (subtype H5N1) in chicken ...

Minosse C, Selleri M, Zaniratti MS, Lauria FN, Pur. Improved detection of human influenza A and B viruses in respiratory tract specimens by hemi-nested PCR. J Virol Methods. 2007 Jan 24.  Abstract  
submitted by kickingbird at Feb, 8, 2007 from J Virol Methods. 2007 Jan 24 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
RT-PCR is the most sensitive assay for diagnosis of influenza, due to enhanced rapidity and sensitivity as compared to classical methods. Hemi-nested RT-PCR was developed, targeting NP gene for influenza ...

Ortiz JR, Wallis TR, Katz MA, Berman LS, Balish A,. No Evidence of Avian Influenza A (H5N1) among Returning US Travelers. Emerg Infect Dis. 2007 Feb Edition.  Abstract  
submitted by kickingbird at Feb, 6, 2007 from Emerg Infect Dis. 2007 Feb Edition (via http://www.cdc.gov/eid/content/13/2/294.htm)
We reviewed reports to the Centers for Disease Control and Prevention of US travelers suspected of having avian influenza A (H5N1) virus infection from February 2003 through May 2006. Among the 59 reported ...

Smallman-Raynor M, Cliff AD. Avian Influenza A (H5N1) Age Distribution in Humans. Emerg Infect Dis. 2007 Mar.  Abstract  
submitted by kickingbird at Feb, 6, 2007 from Emerg Infect Dis. 2007 Mar (via http://www.cdc.gov/eid/content/13/3/06-0849.htm)
To the Editor: A total of 229 confirmed human cases of avian influenza A (H5N1) were reported to the World Health Organization (WHO) from 10 countries of Africa, Asia, and Europe in the 30 months leading ...

Terrence M. Tumpey, etc.,al. A Two-Amino Acid Change in the Hemagglutinin of the 1918 Influenza Virus Abolishes Transmission. Science 2 February 2007.  Abstract  
submitted by kickingbird at Feb, 3, 2007 from Science 2 February 2007 (via http://www.sciencemag.org/cgi/content/abstract/sci;315/5812/)
The 1918 influenza pandemic was a catastrophic series of virus outbreaks that spread across the globe. Here, we show that only a modest change in the 1918 influenza hemagglutinin receptor binding site ...

Leschnik M, Weikel J, M?stl K, Revilla-Fernández S. Subclinical Infection with Avian Influenza A (H5N1) Virus in Cats. Emerg Infect Dis. 2007 Feb Edition.  Abstract  
submitted by kickingbird at Jan, 25, 2007 from Emerg Infect Dis. 2007 Feb Edition (via http://www.cdc.gov/eid/content/13/2/243.htm)
AbstractAvian influenza A virus subtype H5N1 was transmitted to domestic cats by close contact with infected birds. Virus-specific nucleic acids were detected in pharyngeal swabs from 3 of 40 randomly ...

J M Nicholls., etc.,al. Tropism of avian influenza A (H5N1) in the upper and lower respiratory tract. Nature Brief Communication.  Abstract  
submitted by kickingbird at Jan, 24, 2007 from Nature Brief Communication (via http://www.nature.com/nm/journal/vaop/ncurrent/abs/nm1529.ht)
Poor human-to-human transmission of influenza A H5N1 virus has been attributed to the paucity of putative sialic acid 2-3 virus receptors in the epithelium of the human upper respiratory tract, and thus ...

PAN Wei-qi, etc.,al. Rescue of H5N1 Subtype Influenza Virus which Is Lethal to Mice. Journal of Agricultural Biotechnology.  Abstract  
submitted by kickingbird at Jan, 20, 2007 from Journal of Agricultural Biotechnology
Avian influenza virus is acquiring the ability to cross the species barrier between the avian and mammal. However, the genetic mechanism of this ability has not been well known. Influenza A virus A/Chicken/Guangdong/04(H5N1) ...

MATROSOVICH M, Matrosovich T, Uhlendorff J, Garten. Avian-virus-like receptor specificity of the hemagglutinin impedes influenza virus replication in cultures of human airway epithelium. Virology. 2007 Jan 4.  Abstract  
submitted by kickingbird at Jan, 20, 2007 from Virology. 2007 Jan 4 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
A non-optimal receptor-binding specificity of avian influenza viruses is believed to hamper their replication in humans; however, the magnitude of this restriction remains undefined. Here we generated ...

MATSUZAKI Y, Abiko C, Mizuta K, Sugawara K, et al.. A nationwide epidemic of influenza C virus in Japan in 2004. J Clin Microbiol. 2007.  Abstract  
submitted by kickingbird at Jan, 20, 2007 from J Clin Microbiol. 2007 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Department of Infectious Diseases, Yamagata University School of Medicine, Yamagata 990-9585, Japan, Department of Microbiology, Yamagata Prefectural Institute of Public Health, Yamagata 990-0031, Japan, ...

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