Dumm RE, et al. Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function. Nat Commun. 2019 Feb 15;10(1):779. Abstract
submitted by kickingbird at Feb, 19, 2019 from Nat Commun. 2019 Feb 15;10(1):779 (via https://www.ncbi.nlm.nih.gov/pubmed/30770807)
Influenza B virus (IBV) is an acute, respiratory RNA virus that has been assumed to induce the eventual death of all infected cells. We and others have shown however, that infection with apparently cytopathic ... Yeming Wang, et al. Comparative outcomes of adults hospitalized with seasonal influenza A or B virus infection: application of the seven-category ordinal scale. Open Forum Infectious Diseases 15 February 2019. Abstract
submitted by kickingbird at Feb, 19, 2019 from Open Forum Infectious Diseases 15 February 2019 (via https://academic.oup.com/ofid/advance-article/doi/10.1093/of)
ObjectiveTo investigate the difference of disease severity between influenza A and B among hospitalized adults using a novel ordinal scale and existing clinical outcome endpoints.MethodsA prospective, ... Han A, Czajkowski LM, et al. A Dose Finding Study of a Wild-Type Influenza A/H3N2 virus in a Healthy Volunteer Human Challenge Model. Clin Infect Dis. 2019 Feb 16. Abstract
submitted by kickingbird at Feb, 19, 2019 from Clin Infect Dis. 2019 Feb 16 (via https://www.ncbi.nlm.nih.gov/pubmed/30770534)
BACKGROUND: The development of vaccines and therapeutics have relied on healthy volunteer influenza challenge studies. A validated human infection model with wild-type A(H1N1)pdm09 was reported previously.OBJECTIVE: ... James J, et al. The cellular localization of avian influenza virus PB1-F2 protein alters the magnitude of IFN2 promoter and NFκB-dependent promoter antagonism in chicken cells. J Gen Virol. 2019 Jan 23.. Abstract
submitted by kickingbird at Feb, 18, 2019 from J Gen Virol. 2019 Jan 23. (via https://www.ncbi.nlm.nih.gov/pubmed/30672726)
The accessory protein, PB1-F2, of influenza A virus (IAV) functions in a chicken host to prolong infectious virus shedding and thus the transmission window. Here we show that this delay in virus clearance ... Koszalka P, et al. Baloxavir marboxil susceptibility of influenza viruses from the Asia-Pacific, 2012-2018. Antiviral Res. 2019 Feb 13.. Abstract
submitted by kickingbird at Feb, 17, 2019 from Antiviral Res. 2019 Feb 13. (via https://www.ncbi.nlm.nih.gov/pubmed/30771405)
Baloxavir Marboxil (BXM) is an influenza polymerase inhibitor antiviral that binds to the endonuclease region in the PA subunit of influenza A and B viruses. To establish the baseline susceptibility of ... Bolte H, et al. Packaging of the Influenza Virus Genome Is Governed by a Plastic Network of RNA- and Nucleoprotein-Mediated Interactions. J Virol. 2019 Feb 5;93(4). Abstract
submitted by kickingbird at Feb, 17, 2019 from J Virol. 2019 Feb 5;93(4) (via https://www.ncbi.nlm.nih.gov/pubmed/30463968)
The genome of influenza A virus is organized into eight ribonucleoproteins, each composed of a distinct RNA segment bound by the viral polymerase and oligomeric viral nucleoprotein. Packaging sequences ... White MC1, Tao H, Steel J, Lowen AC. H5N8 and H7N9 packaging signals constrain HA reassortment with a seasonal H3N2 influenza A virus. Proc Natl Acad Sci U S A. 2019 Feb 13. Abstract
submitted by kickingbird at Feb, 16, 2019 from Proc Natl Acad Sci U S A. 2019 Feb 13 (via https://www.ncbi.nlm.nih.gov/pubmed/30760600)
Influenza A virus (IAV) has a segmented genome, which (i) allows for exchange of gene segments in coinfected cells, termed reassortment, and (ii) necessitates a selective packaging mechanism to ensure ... Ito M, et al. Characterization of Mouse Monoclonal Antibodies Against the HA of A(H7N9) Influenza Virus. Viruses. 2019 Feb 11;11(2). Abstract
submitted by kickingbird at Feb, 16, 2019 from Viruses. 2019 Feb 11;11(2) (via https://www.ncbi.nlm.nih.gov/pubmed/30754701)
Many cases of human infection with the H7N9 virus have been detected in China since 2013. H7N9 viruses are maintained in chickens and are transmitted to humans at live bird markets. During circulation ... Powell JD, et al. An avian influenza virus A(H7N9) reassortant that recently emerged in the United States with low pathogenic phenotype does not efficiently infect swine. Influenza Other Respir Viruses. 2019 Feb 13.. Abstract
submitted by kickingbird at Feb, 16, 2019 from Influenza Other Respir Viruses. 2019 Feb 13. (via https://www.ncbi.nlm.nih.gov/pubmed/30761746)
In 2017, outbreaks of low and highly pathogenic avian H7N9 viruses were reported in four States in the United States. In total, over 270 000 birds died or were culled, causing significant economic loss. ... McAuley JL, et al. Influenza Virus Neuraminidase Structure and Functions. Front Microbiol. 2019 Jan 29;10:39.. Abstract
submitted by kickingbird at Feb, 16, 2019 from Front Microbiol. 2019 Jan 29;10:39. (via https://www.ncbi.nlm.nih.gov/pubmed/30761095)
With the constant threat of emergence of a novel influenza virus pandemic, there must be continued evaluation of the molecular mechanisms that contribute to virulence. Although the influenza A virus surface ... Vrijens P, et al. Influenza virus entry via the GM3 ganglioside-mediated platelet-derived growth factor receptor β signalling pathway. J Gen Virol. 2019 Feb 14.. Abstract
submitted by kickingbird at Feb, 16, 2019 from J Gen Virol. 2019 Feb 14. (via https://www.ncbi.nlm.nih.gov/pubmed/30762518)
The possible resistance of influenza virus against existing antiviral drugs calls for new therapeutic concepts. One appealing strategy is to inhibit virus entry, in particular at the stage of internalization. ... Asha K, Kumar B. Emerging Influenza D Virus Threat: What We Know so Far!. J Clin Med. 2019 Feb 5;8(2).. Abstract
submitted by kickingbird at Feb, 16, 2019 from J Clin Med. 2019 Feb 5;8(2). (via https://www.ncbi.nlm.nih.gov/pubmed/30764577)
Influenza viruses, since time immemorial, have been the major respiratory pathogen known to infect a wide variety of animals, birds and reptiles with established lineages. They belong to the family Orthomyxoviridae ... Havlickova M, et al. Circulation of influenza A and B in the Czech Republic from 2000-2001 to 2015-2016. BMC Infect Dis. 2019 Feb 14;19(1):160.. Abstract
submitted by kickingbird at Feb, 16, 2019 from BMC Infect Dis. 2019 Feb 14;19(1):160. (via https://www.ncbi.nlm.nih.gov/pubmed/30764763)
BACKGROUND: To improve national influenza vaccination recommendations, additional data on influenza A and B virus circulation are needed. Here, we describe the circulation of influenza A and B in the Czech ... Yang L, et al. Comparison of influenza disease burden in older populations of Hong Kong and Brisbane: the impact of influenza and pneumococcal vaccination. BMC Infect Dis. 2019 Feb 14;19(1):162.. Abstract
submitted by kickingbird at Feb, 16, 2019 from BMC Infect Dis. 2019 Feb 14;19(1):162. (via https://www.ncbi.nlm.nih.gov/pubmed/30764779)
BACKGROUND: Influenza and pneumococcal vaccine uptake in the older population aged 65?years or over of Hong Kong dramatically increased since the 2003 SARS outbreak. This study is aimed to evaluate the ... Kargarfard F, Sami A, Hemmatzadeh F, Ebrahimie E. Identifying mutation positions in all segments of influenza genome enables better differentiation between pandemic and seasonal strains. Gene. 2019 Feb 12. pii: S0378-1119(19)30058-7.. Abstract
submitted by kickingbird at Feb, 16, 2019 from Gene. 2019 Feb 12. pii: S0378-1119(19)30058-7. (via https://www.ncbi.nlm.nih.gov/pubmed/30769139)
Influenza has a negative sense, single-stranded, segmented RNA. In the context of pandemic influenza research, most studies have focused on variations in the surface proteins (Hemagglutinin and Neuraminidase). ... Alguacil-Ramos AM, et al. Rapid assessment of enhanced safety surveillance for influenza vaccine. Public Health. 2019 Feb 12;168:137-141. Abstract
submitted by kickingbird at Feb, 16, 2019 from Public Health. 2019 Feb 12;168:137-141 (via https://www.ncbi.nlm.nih.gov/pubmed/30769245)
OBJECTIVES: The enhanced safety surveillance for seasonal influenza vaccines established by the European Medicines Agency is required each season. Therefore, a registry capable of rapidly detecting and ... Sugawara T, et al. Association of severe abnormal behavior and acetaminophen with/without neuraminidase inhibitors. J Infect Chemother. 2019 Feb 7. Abstract
submitted by kickingbird at Feb, 14, 2019 from J Infect Chemother. 2019 Feb 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30744989)
BACKGROUND: Even though abnormal behavior related with influenza and neuraminidase inhibitors (NI) has been discussed, the risks of acetaminophen and co-administration of NI and acetaminophen have not ... Lytras T, Mouratidou E, Andreopoulou A,et al. Effect of early oseltamivir treatment on mortality in critically ill patients with different types of influenza: a multi-season cohort study. Clin Infect Dis. 2019 Feb 7. Abstract
submitted by kickingbird at Feb, 14, 2019 from Clin Infect Dis. 2019 Feb 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30753349)
Background: The available evidence on whether neuraminidase inhibitors reduce mortality in patients with influenza is inconclusive, and focuses solely on influenza A/H1N1pdm09. We assessed whether early ... Nikolaev EV, Zloza A, Sontag ED. Immunobiochemical Reconstruction of Influenza Lung Infection-Melanoma Skin Cancer Interactions. Front Immunol. 2019 Jan 28;10:4. Abstract
submitted by kickingbird at Feb, 14, 2019 from Front Immunol. 2019 Jan 28;10:4 (via https://www.ncbi.nlm.nih.gov/pubmed/30745900)
It was recently reported that acute influenza infection of the lung promoted distal melanoma growth in the dermis of mice. Melanoma-specific CD8+ T cells were shunted to the lung in the presence of the ... Kwon JH, et al. Different pathogenicity of two strains of clade 2.3.4.4c H5N6 highly pathogenic avian influenza viruses bearing different PA and NS gene in domestic ducks. Virology. 2019 Jan 15;530:11-18. Abstract
submitted by kickingbird at Feb, 14, 2019 from Virology. 2019 Jan 15;530:11-18 (via https://www.ncbi.nlm.nih.gov/pubmed/30753976)
H5Nx clade 2.3.4.4 highly pathogenic avian influenza viruses (HPAIVs) have been disseminated to wide geographic regions since 2014. In 2016, five distinct genotypes (C-1 to C-5) of clade 2.3.4.4c H5N6 ... 9547 items, 20/Page, Page[270/478][|<<] [|<] [261] [262] [263] [264] [265] [266] [267] [268] [269] [270] [>|] [>>|] |
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