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2024-4-29 3:10:11
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TRAVANTY E, Zhou B, Zhang H, Di YP, et al. Differential susceptibility of human lung primary cells to H1N1 influenza viruses. J Virol. 2015 Sep 16..  Abstract  
submitted by kickingbird at Sep, 21, 2015 from J Virol. 2015 Sep 16. (via http://www.ncbi.nlm.nih.gov/pubmed/26378172)
Human alveolar epithelial cells (AECs) and alveolar macrophages (AMs) are the first lines of lung defense. In this study we report that AECs are the direct targets for H1N1 viruses that have circulated ...

TAYLOR G, Abdesselam K, Pelude L, Fernandes R, et. Epidemiological features of influenza in Canadian adult intensive care unit patients. Epidemiol Infect. 2015 Sep 18:1-10..  Abstract  
submitted by kickingbird at Sep, 21, 2015 from Epidemiol Infect. 2015 Sep 18:1-10. (via http://www.ncbi.nlm.nih.gov/pubmed/26384310)
To identify predictive factors and mortality of patients with influenza admitted to intensive care units (ICU) we carried out a prospective cohort study of patients hospitalized with laboratory-confirmed ...

LEI H, Peng X, Zhao D, Jiao H, et al. Cross-protection of Lactococcus lactis-displayed HA2 subunit against homologous and heterologous influenza A viruses in mice. Arch Virol. 2015 Sep 11.  Abstract  
submitted by kickingbird at Sep, 21, 2015 from Arch Virol. 2015 Sep 11 (via http://www.ncbi.nlm.nih.gov/pubmed/26358264)
Current influenza vaccines provide strain-specific protection against homologous subtypes and need to be updated annually. Therefore, it is essential to develop a universal vaccine that would induce broadly ...

WEISS R, Laengle J, Sachet M, Shurygina AP, et al. Interleukin-24 inhibits influenza A virus replication in vitro through induction of toll-like receptor 3 dependent apoptosis. Antiviral Res. 2015 Sep 11..  Abstract  
submitted by kickingbird at Sep, 21, 2015 from Antiviral Res. 2015 Sep 11. (via http://www.ncbi.nlm.nih.gov/pubmed/26367324)
New anti-viral agents and strategies are urgently needed to fight rapidly mutating viruses, as vaccine programs cannot react fast enough to prevent pandemics. Recently, we have shown that interleukin-24 ...

Yuan J, Lau EH, Li K, Leung YH, Yang Z, Xie C, et. Effect of live poultry market closure on avian influenza A(H7N9) virus activity in Guangzhou, China, 2014. Emerg Infect Dis. 2015 Oct.  Abstract  
submitted by kickingbird at Sep, 9, 2015 from Emerg Infect Dis. 2015 Oct (via http://wwwnc.cdc.gov/eid/article/21/10/15-0623_article)
We assessed the effect of closing live poultry markets in China on influenza A(H7N9) virus detection and viability. Intensive sampling was carried out before, during, and after a 2-week citywide market ...

LI Q, Wang X, Sun Z, Hu J, et al. Adaptive mutations in PB2 gene contribute to the high virulence of a natural reassortant H5N2 avian influenza virus in mice. Virus Res. 2015 Aug 24;210:255-263.  Abstract  
submitted by kickingbird at Sep, 7, 2015 from Virus Res. 2015 Aug 24;210:255-263 (via http://www.ncbi.nlm.nih.gov/pubmed/26315686)
The highly pathogenic A/chicken/Hebei/1102/2010 (HB10) H5N2 virus is a natural reassortant derived from circulating H5N1 and endemic H9N2 avian influenza viruses (AIV). To evaluate the potential of its ...

WILSON JR, Guo Z, Tzeng WP, Garten RJ, et al. Diverse antigenic site targeting of influenza hemagglutinin in the murine antibody recall response to A(H1N1)pdm09 virus. Virology. 2015 Aug 25;485:252-262. doi: 10.1016/j.  Abstract  
submitted by kickingbird at Sep, 7, 2015 from Virology. 2015 Aug 25;485:252-262. doi: 10.1016/j (via http://www.ncbi.nlm.nih.gov/pubmed/26318247)
Here we define the epitopes on HA that are targeted by a group of 9 recombinant monoclonal antibodies (rmAbs) isolated from memory B cells of mice, immunized by infection with A(H1N1)pdm09 virus followed ...

HOFFMANN J, Otte A, Thiele S, Lotter H, et al. Sex differences in H7N9 influenza A virus pathogenesis. Vaccine. 2015 Aug 25. pii: S0264-410X(15)01171-8.  Abstract  
submitted by kickingbird at Sep, 7, 2015 from Vaccine. 2015 Aug 25. pii: S0264-410X(15)01171-8 (via http://www.ncbi.nlm.nih.gov/pubmed/26319064)
Sex, gender and age have an impact on incidence and severity of several infectious diseases. Here, we analyzed reported human cases of avian H7N9 influenza A virus infections for potential sex-dependent ...

WIERSMA LC, Vogelzang-van Trierum SE, Kreijtz JH,. Heterosubtypic immunity to H7N9 influenza virus in isogenic guinea pigs after infection with pandemic H1N1 virus. Vaccine. 2015 Aug 25. pii: S0264-410X(15)01165-2.  Abstract  
submitted by kickingbird at Sep, 7, 2015 from Vaccine. 2015 Aug 25. pii: S0264-410X(15)01165-2 (via http://www.ncbi.nlm.nih.gov/pubmed/26319067)
Heterosubtypic immunity is defined as immune-mediated (partial) protection against an influenza virus induced by an influenza virus of another subtype to which the host has not previously been exposed. ...

BOIRON K, Sarazin M, Debin M, Raude J, et al. Opinion about seasonal influenza vaccination among the general population 3 years after the A(H1N1)pdm2009 influenza pandemic. Vaccine. 2015 Aug 28. pii: S0264-410X.  Abstract  
submitted by kickingbird at Sep, 7, 2015 from Vaccine. 2015 Aug 28. pii: S0264-410X (via http://www.ncbi.nlm.nih.gov/pubmed/26322844)
OBJECTIVE: To assess the opinions of the French general population about seasonal influenza vaccination three years after the A(H1N1)pdm 09 pandemic and identify factors associated with a neutral or ...

ZHAO D, Fukuyama S, Yamada S, Lopes TJ, et al. Molecular determinants of virulence and stability of a reporter-expressing H5N1 influenza A virus. J Virol. 2015 Sep 2. pii: JVI.01886-15..  Abstract  
submitted by kickingbird at Sep, 7, 2015 from J Virol. 2015 Sep 2. pii: JVI.01886-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26339046)
We previously reported that an H5N1 virus carrying the Venus reporter gene, which was inserted into the NS gene segment from A/Puerto Rico/8/1934 (H1N1) virus (Venus-H5N1 virus), became more lethal to ...

VERHAGEN JH, Hofle U, van Amerongen G, van de Bild. Long-term effect of serial infections with H13 and H16 low pathogenic avian influenza viruses in black-headed gulls. J Virol. 2015 Sep 2. pii: JVI.01765-15..  Abstract  
submitted by kickingbird at Sep, 7, 2015 from J Virol. 2015 Sep 2. pii: JVI.01765-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26339062)
Infections of domestic and wild birds with low pathogenic avian influenza viruses (LPAIV) have been associated with protective immunity to subsequent infection. However, the degree and duration of immunity ...

WIERSMA LC, Kreijtz JH, Vogelzang-van Trierum SE,. Virus replication kinetics and pathogenesis of infection with H7N9 influenza virus in isogenic guinea pigs upon intratracheal inoculation. Vaccine. 2015 Aug 22. pii: S0264-410X(15)01177-9..  Abstract  
submitted by kickingbird at Aug, 30, 2015 from Vaccine. 2015 Aug 22. pii: S0264-410X(15)01177-9. (via http://www.ncbi.nlm.nih.gov/pubmed/26307235)
Since 2013, avian influenza viruses of subtype H7N9 have been transmitted from poultry to humans in China and caused severe disease. Concerns persist over the pandemic potential of this virus and further ...

SU WC, Hsu SF, Lee YY, Jeng KS, et al. A Nucleolar Protein, Ribosomal RNA Processing 1 Homolog B (RRP1B), Enhances the Recruitment of Cellular mRNA in Influenza Virus Transcription. J Virol. 2015 Aug 26. pii: JVI.01487-15.  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Virol. 2015 Aug 26. pii: JVI.01487-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26311876)
Influenza A virus (IAV) undergoes RNA transcription by a unique capped mRNA-dependent transcription, which is carried out by the viral RNA-dependent RNA polymerase (RdRp), consisting of the viral PA, PB1 ...

REJMANEK D, Hosseini PR, Mazet JA, Daszak P, et al. Evolutionary dynamics and global diversity of influenza A virus. J Virol. 2015 Aug 26. pii: JVI.01573-15..  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Virol. 2015 Aug 26. pii: JVI.01573-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26311890)
The increasing number of zoonotic infections caused by influenza A virus (IAV) subtypes of avian origin in recent years (e.g. H5N1 and H7N9) underscores the need to better understand the factors driving ...

SOLORZANO A, Foni E, Cordoba L, Baratelli M, et al. Cross-species infectivity of H3N8 influenza virus in an experimental infection in swine. J Virol. 2015 Aug 26. pii: JVI.01509-15.  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Virol. 2015 Aug 26. pii: JVI.01509-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26311894)
Avian influenza A viruses have gained increasing attention due to their ability to cross the species barrier and cause severe disease in humans and other mammal species as pigs. H3 and particularly H3N8 ...

RAJAO DS, Gauger PC, Anderson TK, Lewis NS, et al. Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from endemic viruses. J Virol. 2015 Aug 26. pii: JVI.01675-15.  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Virol. 2015 Aug 26. pii: JVI.01675-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26311895)
Human-like swine H3 influenza A viruses (IAV) were detected by the USDA surveillance system. We characterized two novel swine human-like H3N2 and H3N1 viruses with HA genes similar to human seasonal H3 ...

GAO H, Xu G, Sun Y, Qi L, et al. PA-X is a virulence factor in avian H9N2 influenza virus. J Gen Virol. 2015 Jul 9. doi: 10.1099/jgv.0.000232.  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Gen Virol. 2015 Jul 9. doi: 10.1099/jgv.0.000232 (via http://www.ncbi.nlm.nih.gov/pubmed/26296365)
H9N2 influenza viruses have been circulating worldwide in multiple avian species and regularly infect pigs and humans. Recently, a novel protein PA-X, produced from ribosomal frame-shift during PA translation, ...

XU F, Liu G, Liu Q, Zhou Y, et al. RNA interference of influenza A virus replication by microRNA-adapted lentiviral shRNA. J Gen Virol. 2015 Jul 17. doi: 10.1099/jgv.0.00024.  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Gen Virol. 2015 Jul 17. doi: 10.1099/jgv.0.00024 (via http://www.ncbi.nlm.nih.gov/pubmed/26296570)
Limitations of the current vaccines and antivirals against influenza A virus pandemic underscores the urgent need for developing a novel anti-influenza strategies. RNA interference (RNAi) induced by small ...

WU NH, Meng F, Seitz M, Valentin-Weigand P, et al. Sialic acid-dependent interactions between influenza viruses and Streptococcus suis affect the infection of porcine tracheal cells. J Gen Virol. 2015 Jun 25. doi: 10.1099/jgv.0.00022.  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Gen Virol. 2015 Jun 25. doi: 10.1099/jgv.0.00022 (via http://www.ncbi.nlm.nih.gov/pubmed/26297001)
Bacterial co-infections are a major complication in influenza virus-induced disease both in humans and animals. Either of the pathogens may induce a host response that affects the infection by the other ...

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