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2024-5-2 13:33:23
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McMahon M, Tan J, O´Dell G, Kirkpatrick Roub. Immunity induced by vaccination with recombinant influenza B virus neuraminidase protein breaks viral transmission chains in guinea pigs in an exposure intensity-dependent manner. J Virol. 2023 Oct 6:e0105723.  Abstract  
submitted by kickingbird at Oct, 7, 2023 from J Virol. 2023 Oct 6:e0105723 (via https://journals.asm.org/doi/10.1128/jvi.01057-23)
Mucosal vaccines and vaccines that block pathogen transmission are under-appreciated in vaccine development. However, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has shown ...

Lebarbenchon C, Boucher S, Feare C, Dietrich M, La. Migratory patterns of two major influenza virus host species on tropical islands. R Soc Open Sci. 2023 Oct 4;10(10):230600.  Abstract  
submitted by kickingbird at Oct, 7, 2023 from R Soc Open Sci. 2023 Oct 4;10(10):230600 (via https://royalsocietypublishing.org/doi/10.1098/rsos.230600)
Animal migration is a major driver of infectious agent dispersal. Duck and seabird migrations, for instance, play a key role in the spatial transmission dynamics and gene flow of avian influenza viruses ...

Long Qin,etc.,al. Genetic characteristics of the first human infection with the G4 genotype eurasian avian-like H1N1 swine influenza virus in Shaanxi Province,China. DOI:10.3760/cma.j.cn112150-20220926-00924.  Abstract  
submitted by kickingbird at Oct, 5, 2023 from DOI:10.3760/cma.j.cn112150-20220926-00924 (via https://rs.yiigle.com/cmaid/1474489)
ObjectiveTo analyze the genetic characteristics of the first human infection with the G4 genotype of Eurasian avian H1N1 swine influenza virus (EA H1N1 SIV) in Shaanxi Province.MethodsThe patient′s throat ...

Jbenyeni A, Croville G, Cazaban C, Guérin JL. Predominance of low pathogenic avian influenza virus H9N2 in the respiratory co-infections in broilers in Tunisia: a longitudinal field study, 2018-2020. Vet Res. 2023 Oct 3;54(1):88.  Abstract  
submitted by kickingbird at Oct, 5, 2023 from Vet Res. 2023 Oct 3;54(1):88 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Respiratory diseases are a health and economic concern for poultry production worldwide. Given global economic exchanges and migratory bird flyways, respiratory viruses are likely to emerge continuously ...

Kikuchi C, Antonopoulos A, Wang S, Maemura T, Kara. Glyco-engineered MDCK cells display preferred receptors of H3N2 influenza absent in eggs used for vaccines. Nat Commun. 2023 Oct 4;14(1):6178.  Abstract  
submitted by kickingbird at Oct, 5, 2023 from Nat Commun. 2023 Oct 4;14(1):6178 (via https://www.nature.com/articles/s41467-023-41908-0)
Evolution of human H3N2 influenza viruses driven by immune selection has narrowed the receptor specificity of the hemagglutinin (HA) to a restricted subset of human-type (Neu5Acα2-6 Gal) glycan receptors ...

Sumner KM, Masalovich S, O´Halloran A, Holst. Severity of influenza-associated hospitalisations by influenza virus type and subtype in the USA, 2010-19: a repeated cross-sectional study. Lancet Microbe. 2023 Sep 25:S2666-5247(23)00187-8.  Abstract  
submitted by kickingbird at Oct, 1, 2023 from Lancet Microbe. 2023 Sep 25:S2666-5247(23)00187-8 (via https://www.thelancet.com/journals/lanmic/article/PIIS2666-5)
Background: Influenza burden varies across seasons, partly due to differences in circulating influenza virus types or subtypes. Using data from the US population-based surveillance system, Influenza Hospitalization ...

Andreev K, Jones JC, Seiler P, Kandeil A, Turner J. Antiviral Susceptibility of Highly Pathogenic Avian Influenza A(H5N1) Viruses Circulating Globally in 2022-2023. J Infect Dis. 2023 Sep 28:jiad418.  Abstract  
submitted by kickingbird at Oct, 1, 2023 from J Infect Dis. 2023 Sep 28:jiad418 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
The antiviral susceptibility of currently circulating (2022-2023) highly pathogenic avian influenza (HPAI) A(H5N1) viruses was assessed by genotypic and phenotypic approaches. The frequency of neuraminidase ...

Barkhasbaatar A, Gilbert M, Fine AE, Shiilegdamba. Ecological characterization of 175 low-pathogenicity avian influenza viruses isolated from wild birds in Mongolia, 2009-2013 and 2016-2018. Vet Med Sci. 2023 Sep 28.  Abstract  
submitted by kickingbird at Oct, 1, 2023 from Vet Med Sci. 2023 Sep 28 (via https://onlinelibrary.wiley.com/doi/10.1002/vms3.1281)
Background: Since 2005, highly pathogenic avian influenza A H5N1 viruses have spread from Asia worldwide, infecting poultry, humans and wild birds. Subsequently, global interest in avian influenza (AI) ...

Lei Y, Sun Y, Wu W, Liu H, Wang X, Shu Y, Fang S. Influenza H7N9 virus disrupts the monolayer human brain microvascular endothelial cells barrier in vitro. Virol J. 2023 Sep 29;20(1):219.  Abstract  
submitted by kickingbird at Oct, 1, 2023 from Virol J. 2023 Sep 29;20(1):219 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Influenza H7N9 virus causes human infections with about 40% case fatality rate. The severe cases usually present with pneumonia; however, some present with central nervous system complications. Pneumonia ...

Wang S, Zhang TH, Hu M, Tang K, Sheng L, Hong M, C. Deep mutational scanning of influenza A virus neuraminidase facilitates the identification of drug resistance mutations in vivo. mSystems. 2023 Sep 29:e0067023.  Abstract  
submitted by kickingbird at Oct, 1, 2023 from mSystems. 2023 Sep 29:e0067023 (via https://journals.asm.org/doi/10.1128/msystems.00670-23)
Neuraminidase (NA) is a pivotal surface enzyme and a key therapeutic target in combating the influenza A virus. Its evolution can lead to potential zoonotic transmission, seasonal epidemics, and the emergence ...

Nabeshima K, Takadate Y, Soda K, Hiono T, Isoda N,. Detection of H5N1 High Pathogenicity Avian Influenza Viruses in Four Raptors and Two Geese in Japan in the Fall of 2022. Viruses. 2023 Sep 1;15(9):1865.  Abstract  
submitted by kickingbird at Sep, 29, 2023 from Viruses. 2023 Sep 1;15(9):1865 (via https://www.mdpi.com/1999-4915/15/9/1865)
In the fall of 2022, high pathogenicity avian influenza viruses (HPAIVs) were detected from raptors and geese in Japan, a month earlier than in past years, indicating a shift in detection patterns. In ...

Alkie TN, Byrne AMP, Jones MEB, Mollett BC, Bourqu. Recurring Trans-Atlantic Incursion of Clade 2.3.4.4b H5N1 Viruses by Long Distance Migratory Birds from Northern Europe to Canada in 2022/2023. Viruses. 2023 Aug 30;15(9):1836.  Abstract  
submitted by kickingbird at Sep, 29, 2023 from Viruses. 2023 Aug 30;15(9):1836 (via https://www.mdpi.com/1999-4915/15/9/1836)
In December 2022 and January 2023, we isolated clade 2.3.4.4b H5N1 high-pathogenicity avian influenza (HPAI) viruses from six American crows (Corvus brachyrhynchos) from Prince Edward Island and a red ...

Petrich A, Chiantia S. Influenza A Virus Infection Alters Lipid Packing and Surface Electrostatic Potential of the Host Plasma Membrane. Viruses. 2023 Aug 29;15(9):1830.  Abstract  
submitted by kickingbird at Sep, 29, 2023 from Viruses. 2023 Aug 29;15(9):1830 (via https://www.mdpi.com/1999-4915/15/9/1830)
The pathogenesis of influenza A viruses (IAVs) is influenced by several factors, including IAV strain origin and reassortment, tissue tropism and host type. While such factors were mostly investigated ...

Kanekiyo M, Gillespie RA, Midgett M, O´Malle. Refined semi-lethal aerosol H5N1 influenza model in cynomolgus macaques for evaluation of medical countermeasures. iScience. 2023 Sep 6;26(10):107830.  Abstract  
submitted by kickingbird at Sep, 29, 2023 from iScience. 2023 Sep 6;26(10):107830 (via https://www.cell.com/iscience/fulltext/S2589-0042(23)01907-7)
Highly pathogenic avian influenza A H5N1 viruses cause high mortality in humans and have pandemic potential. Effective vaccines and treatments against this threat are urgently needed. Here, we have refined ...

Marandino A, Tomás G, Panzera Y, Leizagoyen C, Pér. Spreading of the High-Pathogenicity Avian Influenza (H5N1) Virus of Clade 2.3.4.4b into Uruguay. Viruses. 2023 Sep 11;15(9):1906.  Abstract  
submitted by kickingbird at Sep, 29, 2023 from Viruses. 2023 Sep 11;15(9):1906 (via https://www.mdpi.com/1999-4915/15/9/1906)
Background: Avian influenza viruses (genus Alphainfluenzavirus, family Orthomyxoviridae) infect avian and mammal hosts. In 2022, the high pathogenicity avian influenza virus (H5N1) spread to South America, ...

Seekings AH, Warren CJ, Thomas SS, Lean FZX, Selde. Different Outcomes of Chicken Infection with UK-Origin H5N1-2020 and H5N8-2020 High-Pathogenicity Avian Influenza Viruses (Clade 2.3.4.4b). Viruses. 2023 Sep 12;15(9):1909.  Abstract  
submitted by kickingbird at Sep, 29, 2023 from Viruses. 2023 Sep 12;15(9):1909 (via https://www.mdpi.com/1999-4915/15/9/1909)
Clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses (HPAIVs) of the "goose/Guangdong" lineage have caused a series of European epizootics since 2014. During autumn/winter 2020-2021, several H5Nx ...

Ulloa M, Fernández A, Ariyama N, Colom-Rivero A, R. Mass Mortality Event in South American Sea Lions ( Otaria flavescens) Correlated to Highly Pathogenic Avian Influenza (HPAI) H5N1 Outbreak in Chile. Vet Q. 2023 Sep 28:1-13.  Abstract  
submitted by kickingbird at Sep, 29, 2023 from Vet Q. 2023 Sep 28:1-13 (via https://www.tandfonline.com/doi/full/10.1080/01652176.2023.2)
In Chile, since January 2023, a sudden and pronounced increase in strandings and mortality has been observed among South American (SA) sea lions (Otaria flavescens), prompting significant concern. Simultaneously, ...

Takashita E, Fujisaki S, Morita H, Nagata S, Miura. A community cluster of influenza A(H3N2) virus infection with reduced susceptibility to baloxavir due to a PA E199G substitution in Japan, February to March 2023. Euro Surveill. 2023 Sep;28(39).  Abstract  
submitted by kickingbird at Sep, 29, 2023 from Euro Surveill. 2023 Sep;28(39) (via https://pubmed.ncbi.nlm.nih.gov/37768560/)
A community cluster of influenza A(H3N2) caused by viruses with an E199G substitution in PA was detected in Nara, Japan, between February and March 2023. The three patients with these mutant viruses had ...

Pepin KM, Leach CB, Barrett NL, Ellis JW, VanDalen. Environmental transmission of influenza A virus in mallards. mBio. 2023 Sep 28:e0086223.  Abstract  
submitted by kickingbird at Sep, 29, 2023 from mBio. 2023 Sep 28:e0086223 (via https://journals.asm.org/doi/10.1128/mbio.00862-23)
Influenza A viruses present a major challenge for animal and human health. They circulate widely in wild waterfowl and frequently spillover into poultry, emphasizing the need for risk-based surveillance ...

Soda K, Mekata H, Usui T, Ito H, Matsui Y, Yamada. Genetic and antigenic analyses of H5N8 and H5N1 subtypes high pathogenicity avian influenza viruses isolated from wild birds and poultry farms in Japan in the winter of 2021-2022. J Vet Med Sci. 2023 Sep 26.  Abstract  
submitted by kickingbird at Sep, 29, 2023 from J Vet Med Sci. 2023 Sep 26 (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_23)
In the winter of 2021-2022, multiple subtypes (H5N8 and H5N1) of high pathogenicity avian influenza viruses (HPAIVs) were confirmed to be circulating simultaneously in Japan. Here, we phylogenetically ...

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