Kikuchi T, Watanabe A. Baloxavir heralds a new era in influenza virus biology. Respir Investig. 2018 Nov 2. Abstract
submitted by kickingbird at Nov, 7, 2018 from Respir Investig. 2018 Nov 2 (via https://www.ncbi.nlm.nih.gov/pubmed/30396860)
Baloxavir marboxil is an orally available prodrug of baloxavir acid. Japan was the first country to approve baloxavir marboxil as a treatment for influenza. The antiviral mechanism of action of baloxavir ... Il Kim J, et al. Distinct molecular evolution of influenza H3N2 strains in the 2016/17 season and its implications for vaccine effectiveness. Mol Phylogenet Evol. 2018 Nov 3.. Abstract
submitted by kickingbird at Nov, 7, 2018 from Mol Phylogenet Evol. 2018 Nov 3. (via https://www.ncbi.nlm.nih.gov/pubmed/30399431)
Influenza virus is a respiratory pathogen that causes seasonal epidemics by resulting in a considerable number of influenza-like illness (ILI) patients. During the 2016/17 season, ILI rates increased unusually ... Alkie TN, Yitbarek A, Taha-Abdelaziz K, et al. Characterization of immunogenicity of avian influenza antigens encapsulated in PLGA nanoparticles following mucosal and subcutaneous delivery in chickens. PLoS One. 2018 Nov 1;13(11):e0206324. Abstract
submitted by kickingbird at Nov, 6, 2018 from PLoS One. 2018 Nov 1;13(11):e0206324 (via https://www.ncbi.nlm.nih.gov/pubmed/30383798)
Mucosal vaccine delivery systems have paramount importance for the induction of mucosal antibody responses. Two studies were conducted to evaluate immunogenicity of inactivated AIV antigens encapsulated ... KyungHyun Lee, et al. Highly Pathogenic Avian Influenza A(H5N6) in Domestic Cats, South Korea. Emerg Infect Dis. 2018 Dec. Abstract
submitted by kickingbird at Nov, 3, 2018 from Emerg Infect Dis. 2018 Dec (via https://wwwnc.cdc.gov/eid/article/24/12/18-0290_article)
In December 2016, highly pathogenic avian influenza (HPAI) infection with systemic pathological lesions was found in cats in South Korea. Genetic analyses indicated that the feline isolates were similar ... Sun J, Brooke CB. Influenza A Virus Superinfection Potential Is Regulated by Viral Genomic Heterogeneity. MBio. 2018 Oct 30;9(5). Abstract
submitted by kickingbird at Nov, 3, 2018 from MBio. 2018 Oct 30;9(5) (via https://www.ncbi.nlm.nih.gov/pubmed/30377278)
Defining the specific factors that govern the evolution and transmission of influenza A virus (IAV) populations is of critical importance for designing more-effective prediction and control strategies. ... Goldhill DH, et al. Determining the Mutation Bias of Favipiravir in Influenza Using Next-generation Sequencing. J Virol. 2018 Oct 31. Abstract
submitted by kickingbird at Nov, 3, 2018 from J Virol. 2018 Oct 31 (via https://www.ncbi.nlm.nih.gov/pubmed/30381482)
avipiravir is a broad-spectrum antiviral drug that may be used to treat influenza. Previous research has identified that favipiravir likely acts as a mutagen but the precise mutation bias that favipiravir ... Prachanronarong KL, et al. Mutations in influenza A virus neuraminidase and hemagglutinin confer resistance against a broadly neutralizing hemagglutinin stem antibody. J Virol. 2018 Oct 31. Abstract
submitted by kickingbird at Nov, 3, 2018 from J Virol. 2018 Oct 31 (via https://www.ncbi.nlm.nih.gov/pubmed/30381484)
Influenza A virus (IAV), a major cause of human morbidity and mortality, continuously evolves in response to selective pressures. Stem-directed, broadly neutralizing antibodies (sBnAbs) targeting influenza ... Meliopoulos V, et al. Absence of β6 integrin reduces influenza disease severity in highly susceptible obese mice. J Virol. 2018 Oct 31.. Abstract
submitted by kickingbird at Nov, 3, 2018 from J Virol. 2018 Oct 31. (via https://www.ncbi.nlm.nih.gov/pubmed/30381485)
Obese individuals are considered a high-risk group for developing severe influenza virus infection. While the exact mechanisms for increased disease severity remain under investigation, obese mouse models ... Sun W, et al. Antibody responses towards the major antigenic sites of influenza B virus hemagglutinin in mice, ferrets and humans. J Virol. 2018 Oct 31. Abstract
submitted by kickingbird at Nov, 3, 2018 from J Virol. 2018 Oct 31 (via https://www.ncbi.nlm.nih.gov/pubmed/30381487)
The influenza B virus hemagglutinin contains four major antigenic sites (the 120 loop, the 150 loop, the 160 loop and the 190 helix) within the head domain. These immunodominant antigenic sites are the ... Wang SC, Liao HY, Zhang JY, Cheng TR, Wong CH. Development of a universal influenza vaccine using hemagglutinin stem protein produced from Pichia pastoris. Virology. 2018 Oct 26;526:125-137. Abstract
submitted by kickingbird at Nov, 3, 2018 from Virology. 2018 Oct 26;526:125-137 (via https://www.ncbi.nlm.nih.gov/pubmed/30388628)
The development of a universal influenza vaccine has become a major effort to combat the high mutation rate of influenza. To explore the use of the highly conserved stem region of hemagglutinin (HA) as ... Bhardwaj J, Sharma A, Jang J. Vertical flow-based paper immunosensor for rapid electrochemical and colorimetric detection of influenza virus using a different pore size sample pad. Biosens Bioelectron. 2018 Oct 19;126:36-43. Abstract
submitted by kickingbird at Nov, 3, 2018 from Biosens Bioelectron. 2018 Oct 19;126:36-43 (via https://www.ncbi.nlm.nih.gov/pubmed/30388552)
We present a novel vertical flow-based paper immunosensor for the rapid and sensitive electrochemical and colorimetric detection of influenza H1N1 viruses using a different pore size (DP) sample pad. The ... Hussain S, et al. Mutation of influenza A virus PA-X decreases pathogenicity in chicken embryos and can increase the yield of reassortant candidate vaccine viruses. J Virol. 2018 Oct 31.. Abstract
submitted by kickingbird at Nov, 3, 2018 from J Virol. 2018 Oct 31. (via https://www.ncbi.nlm.nih.gov/pubmed/30381488)
The PA-X protein of influenza A virus has roles in host cell shut-off and viral pathogenesis. While most strains are predicted to encode PA-X, strain-dependent variations in activity have been noted. We ... Houser KV, et al. DNA vaccine priming for seasonal influenza vaccine in children and adolescents 6 to 17 years of age: A phase 1 randomized clinical trial. PLoS One. 2018 Nov 2;13(11):e0206837. Abstract
submitted by kickingbird at Nov, 3, 2018 from PLoS One. 2018 Nov 2;13(11):e0206837 (via https://www.ncbi.nlm.nih.gov/pubmed/30388160)
BACKGROUND: Children are susceptible to severe influenza infections and facilitate community transmission. One potential strategy to improve vaccine immunogenicity in children against seasonal influenza ... Zeller MA, et al. ISU FLUture: a veterinary diagnostic laboratory web-based platform to monitor the temporal genetic patterns of Influenza A virus in swine. BMC Bioinformatics. 2018 Nov 1;19(1):397. Abstract
submitted by kickingbird at Nov, 3, 2018 from BMC Bioinformatics. 2018 Nov 1;19(1):397 (via https://www.ncbi.nlm.nih.gov/pubmed/30382842)
BACKGROUND: Influenza A Virus (IAV) causes respiratory disease in swine and is a zoonotic pathogen. Uncontrolled IAV in swine herds not only affects animal health, it also impacts production through increased ... Liu XX, et al. Effects of air pollutants on occurrences of influenza-like illness and laboratory-confirmed influenza in Hefei, China. Int J Biometeorol. 2018 Oct 31. Abstract
submitted by kickingbird at Nov, 3, 2018 from Int J Biometeorol. 2018 Oct 31 (via https://www.ncbi.nlm.nih.gov/pubmed/30382350)
Accumulating evidence suggests that air pollution is a risk factor for adverse respiratory and cardiovascular health outcomes. However, the different impacts of exposure to air pollutants on influenza ... Kandeil A, et al. Isolation and characterization of a distinct influenza A virus from Egyptian bats. J Virol. 2018 Oct 31.. Abstract
submitted by kickingbird at Nov, 3, 2018 from J Virol. 2018 Oct 31. (via https://www.ncbi.nlm.nih.gov/pubmed/30381492)
Recently, two genetically distinct influenza viruses were detected in bats in Guatemala and Peru. We conducted influenza A surveillance among four bat species in Egypt. Out of 1202 swabs, 105 were positive ... Saito S, Nakauchi M, Takayama I, Nagata S, et al. Development and evaluation of new real-time RT-PCR assays for identifying the influenza A virus Cluster IV H3N2 variant. Jpn J Infect Dis. 2018 Oct 31. Abstract
submitted by kickingbird at Nov, 3, 2018 from Jpn J Infect Dis. 2018 Oct 31 (via https://www.ncbi.nlm.nih.gov/pubmed/30381693)
From 2005 to July 6, 2018, a total of 435 swine-origin influenza A H3N2 variant virus (H3N2v) human infections were reported in the USA. The largest H3N2v outbreak in the USA occurred in 2011-2012. This ... Insel M, Natt B, Mosier J, Malo J, Bime C. The Association of Non-Cardiac ECMO With Influenza Incidence: A Time Series Analysis. Respir Care. 2018 Oct 30. Abstract
submitted by kickingbird at Nov, 3, 2018 from Respir Care. 2018 Oct 30 (via https://www.ncbi.nlm.nih.gov/pubmed/30377246)
BACKGROUND: The 2009 H1N1 influenza epidemic saw a rise in the use of extracorporeal membrane oxygenation (ECMO) as a supportive therapy for refractory ARDS. We sought to determine whether ECMO utilization ... Murakami S, Horimoto T. Novel type D influenza virus. Uirusu. 2017;67(2):161-170. Abstract
submitted by kickingbird at Oct, 31, 2018 from Uirusu. 2017;67(2):161-170 (via https://www.ncbi.nlm.nih.gov/pubmed/30369540)
Influenza viruses have been known to be types A to C, including human seasonal influenza virus and avian influenza virus. In recent years, the influenza D virus, which possesses different characteristics ... Wille M, Br?jer C, Lundkvist ?, J?rhult JD. Alternate routes of influenza A virus infection in Mallard (Anas platyrhynchos). Vet Res. 2018 Oct 29;49(1):110. Abstract
submitted by kickingbird at Oct, 31, 2018 from Vet Res. 2018 Oct 29;49(1):110 (via https://www.ncbi.nlm.nih.gov/pubmed/30373662)
The natural reservoir for all influenza A viruses (IAVs) is wild birds, particularly dabbling ducks. During the autumn, viral prevalence can be very high in dabbling ducks (>?30%) in the Northern Hemisphere, ... 7530 items, 20/Page, Page[182/377][|<<] [|<] [181] [182] [183] [184] [185] [186] [187] [188] [189] [190] [>|] [>>|] |
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