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2024-4-28 8:52:28
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Fleming-Canepa X, et al. Duck innate immune responses to high and low pathogenicity H5 avian influenza viruses. Vet Microbiol. 2019 Jan;228:101-111.  Abstract  
submitted by kickingbird at Dec, 30, 2018 from Vet Microbiol. 2019 Jan;228:101-111 (via https://www.ncbi.nlm.nih.gov/pubmed/30593354)
Ducks are the reservoir host of influenza A viruses, and are permissive for replication of most strains, yet can elicit robust innate immune responses to highly pathogenic strains. Tissue tropism and viral ...

Yu Z, He H, Cheng K, Wu J, Gao Y, Chen W, et al. Genetic characterization of an H13N2 low pathogenic avian influenza virus isolated from gulls in China. Transbound Emerg Dis. 2018 Dec 22..  Abstract  
submitted by kickingbird at Dec, 25, 2018 from Transbound Emerg Dis. 2018 Dec 22. (via https://www.ncbi.nlm.nih.gov/pubmed/30578616)
Low pathogenic avian influenza viruses circulate in wild birds but are occasionally transmitted to other species, including poultry, mammals, and humans. To date, infections with low pathogenic avian influenza ...

Rahim MN, Klewes L, Zahedi-Amiri A, et al. Global Interactomics Connect Nuclear Mitotic Apparatus Protein NUMA1 to Influenza Virus Maturation. Viruses. 2018 Dec 19;10(12).  Abstract  
submitted by kickingbird at Dec, 24, 2018 from Viruses. 2018 Dec 19;10(12) (via https://www.ncbi.nlm.nih.gov/pubmed/30572664)
Influenza A virus (IAV) infections remain a major human health threat. IAV has enormous genetic plasticity and can rapidly escape virus-targeted anti-viral strategies. Thus, there is increasing interest ...

Skibinski DAG, et al. Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine. Sci Rep. 2018 Dec 20;8(1):18007.  Abstract  
submitted by kickingbird at Dec, 24, 2018 from Sci Rep. 2018 Dec 20;8(1):18007 (via https://www.ncbi.nlm.nih.gov/pubmed/30573748)
Cell mediated immunity plays a vital role in defense against influenza infection in humans. Less is known about the role of vaccine-induced cell mediated immunity and the cytokine responses elicited. We ...

Pawestri HA, Nugraha AA, Hariastuti NI, Setiawaty. Detection of neuraminidase inhibitor-resistant influenza A (H1N1)pdm09 viruses obtained from influenza surveillance in Indonesia. SAGE Open Med. 2018 Dec 10;6:2050312118818293.  Abstract  
submitted by kickingbird at Dec, 24, 2018 from SAGE Open Med. 2018 Dec 10;6:2050312118818293 (via https://www.ncbi.nlm.nih.gov/pubmed/30574303)
Background: Influenza antiviral resistance has been shown to occur in many countries and is commonly found in influenza A(H1N1)pdm09 and A(H3N2). In this study, we monitored and investigated the neuraminidase ...

Briand FX, et al. Identification of a Divergent Avian Influenza H3N2 Virus from Domestic Ducks in France. Microbiol Resour Announc. 2018 Dec 13;7(23).  Abstract  
submitted by kickingbird at Dec, 24, 2018 from Microbiol Resour Announc. 2018 Dec 13;7(23) (via https://www.ncbi.nlm.nih.gov/pubmed/30574576)
An avian influenza H3N2 virus was isolated from domestic ducks in France in 2016. Although this French H3N2 virus possesses traits of an avian virus, the genetic distances observed for hemagglutinin (HA) ...

Yoshihara K, et al. Influenza B associated Paediatric Acute Respiratory Infection Hospitalization in Central Vietnam. Influenza Other Respir Viruses. 2018 Dec 21.  Abstract  
submitted by kickingbird at Dec, 24, 2018 from Influenza Other Respir Viruses. 2018 Dec 21 (via https://www.ncbi.nlm.nih.gov/pubmed/30575288)
BACKGROUND: Influenza B is one of the major etiologies for acute respiratory infections (ARI) among children worldwide; however, its clinical-epidemiological information is limited. We aimed to investigate ...

Yin R, Tran VH, Zhou X, Zheng J, Kwoh CK. Predicting antigenic variants of H1N1 influenza virus based on epidemics and pandemics using a stacking model. PLoS One. 2018 Dec 21;13(12):e0207777..  Abstract  
submitted by kickingbird at Dec, 24, 2018 from PLoS One. 2018 Dec 21;13(12):e0207777. (via https://www.ncbi.nlm.nih.gov/pubmed/30576319)
H1N1 is the earliest emerging subtype of influenza A viruses with available genomic sequences, has caused several pandemics and seasonal epidemics, resulting in millions of deaths and enormous economic ...

Hong BT, Cheng YE, Cheng TJ, Fang JM. Boronate, trifluoroborate, sulfone, sulfinate and sulfonate congeners of oseltamivir carboxylic acid: Synthesis and anti-influenza activity. Eur J Med Chem. 2018 Dec 13;163:710-721.  Abstract  
submitted by kickingbird at Dec, 24, 2018 from Eur J Med Chem. 2018 Dec 13;163:710-721 (via https://www.ncbi.nlm.nih.gov/pubmed/30576902)
Tamiflu readily undergoes endogenous hydrolysis to give oseltamivir carboxylic acid (OC) as the active anti-influenza agent to inhibit the viral neuraminidase (NA). GOC is derived from OC by replacing ...

Sealy JE, Yaqub T, Peacock TP, Chang P, et al. Association of Increased Receptor-Binding Avidity of Influenza A(H9N2) Viruses with Escape from Antibody-Based Immunity and Enhanced Zoonotic Potential. Emerg Infect Dis. 2019 Jan;25(1):63-72.  Abstract  
submitted by kickingbird at Dec, 23, 2018 from Emerg Infect Dis. 2019 Jan;25(1):63-72 (via https://wwwnc.cdc.gov/eid/article/25/1/18-0616_article)
We characterized 55 influenza A(H9N2) viruses isolated in Pakistan during 2014-2016 and found that the hemagglutinin gene is of the G1 lineage and that internal genes have differentiated into a variety ...

Chen H, Alvarez JJS, Ng SH, Nielsen R, Zhai W. Passage adaptation correlates with the reduced efficacy of the influenza vaccine. Clin Infect Dis. 2018 Dec 18..  Abstract  
submitted by kickingbird at Dec, 23, 2018 from Clin Infect Dis. 2018 Dec 18. (via https://www.ncbi.nlm.nih.gov/pubmed/30561532)
Background: As a dominant seasonal influenza virus, H3N2 virus rapidly evolves in human and is a constant threat to public health. Despite sustained research efforts, the efficacy of H3N2 vaccine has decreased ...

van Asten L, et al. Estimating severity of influenza epidemics from severe acute respiratory infections (SARI) in intensive care units. Crit Care. 2018 Dec 19;22(1):351.  Abstract  
submitted by kickingbird at Dec, 23, 2018 from Crit Care. 2018 Dec 19;22(1):351 (via https://www.ncbi.nlm.nih.gov/pubmed/30567568)
BACKGROUND: While influenza-like-illness (ILI) surveillance is well-organized at primary care level in Europe, few data are available on more severe cases. With retrospective data from intensive care units ...

Zhang J, Su R, Jian X, An H, Jiang R, Mok CKP. The D253N Mutation in the Polymerase Basic 2 Gene in Avian Influenza (H9N2) Virus Contributes to the Pathogenesis of the Virus in Mammalian Hosts. Virol Sin. 2018 Dec 19..  Abstract  
submitted by kickingbird at Dec, 23, 2018 from Virol Sin. 2018 Dec 19. (via https://www.ncbi.nlm.nih.gov/pubmed/30569291)
Mutations in the polymerase basic 2 (PB2) gene of avian influenza viruses are important signatures for their adaptation to mammalian hosts. Various adaptive mutations have been identified around the 627 ...

Rojas-Quintero J, et al. Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection. JCI Insight. 2018 Dec 20;3(24)..  Abstract  
submitted by kickingbird at Dec, 23, 2018 from JCI Insight. 2018 Dec 20;3(24). (via https://www.ncbi.nlm.nih.gov/pubmed/30568032)
Matrix metalloproteinase-9 (MMP-9) cleaves various proteins to regulate inflammatory and injury responses. However, MMP-9's activities during influenza A viral (IAV) infections are incompletely understood. ...

Obadan AO, et al. Flexibility in vitro of amino acid 226 in the receptor-binding site of an H9 subtype influenza A virus and its effect in vivo on virus replication, tropism, and transmission. J Virol. 2018 Dec 19..  Abstract  
submitted by kickingbird at Dec, 23, 2018 from J Virol. 2018 Dec 19. (via https://www.ncbi.nlm.nih.gov/pubmed/30567980)
Influenza A viruses remain a significant public health threat causing more than 300,000 hospitalizations in the United states during 2015-2016 season alone. While only few IAVs of avian origin have been ...

Yin R, Zhou X, Zheng J, Kwoh CK. Computational identification of physicochemical signatures for host tropism of influenza A virus. J Bioinform Comput Biol. 2018 Oct 30:1840023..  Abstract  
submitted by kickingbird at Dec, 23, 2018 from J Bioinform Comput Biol. 2018 Oct 30:1840023. (via https://www.ncbi.nlm.nih.gov/pubmed/30567479)
Avian influenza viruses from migratory birds have managed to cross host species barriers and infected various hosts like human and swine. Epidemics and pandemics might occur when influenza viruses are ...

Howard LM, et al. AS03-Adjuvanted H5N1 Avian Influenza Vaccine Modulates Early Innate Immune Signatures In Human Peripheral Blood Mononuclear Cells. J Infect Dis. 2018 Dec 19.  Abstract  
submitted by kickingbird at Dec, 21, 2018 from J Infect Dis. 2018 Dec 19 (via https://www.ncbi.nlm.nih.gov/pubmed/30566602)
Background: Adjuvant System 03 (AS03) markedly enhances responses to influenza A/H5N1 vaccines, but the mechanisms of this enhancement are incompletely understood.Methods: Using RNA-Seq on peripheral blood ...

Zhou P, et al. Serological Evidence of H3N2 Canine Influenza Virus Infection among Horses with Dog Exposure. Transbound Emerg Dis. 2018 Dec 19.  Abstract  
submitted by kickingbird at Dec, 21, 2018 from Transbound Emerg Dis. 2018 Dec 19 (via https://www.ncbi.nlm.nih.gov/pubmed/30565867)
Currently, Canine influenza virus (CIV) H3N2 is continuously circulating in dog populations in China, Korea, and the United States (US). Both influenza SA-α-2,3-Gal and SA-α-2,6-Gal receptors have been ...

Wu T, Perrings C. The live poultry trade and the spread of highly pathogenic avian influenza: Regional differences between Europe, West Africa, and Southeast Asia. PLoS One. 2018 Dec 19;13(12):e0208197..  Abstract  
submitted by kickingbird at Dec, 21, 2018 from PLoS One. 2018 Dec 19;13(12):e0208197. (via https://www.ncbi.nlm.nih.gov/pubmed/30566454)
In the past two decades, avian influenzas have posed an increasing international threat to human and livestock health. In particular, highly pathogenic avian influenza H5N1 has spread across Asia, Africa, ...

Bischoff WE, et al. How well do N95 respirators protect healthcare providers against aerosolized influenza virus?. Infect Control Hosp Epidemiol. 2018 Dec 18:1-3..  Abstract  
submitted by kickingbird at Dec, 20, 2018 from Infect Control Hosp Epidemiol. 2018 Dec 18:1-3. (via https://www.ncbi.nlm.nih.gov/pubmed/30558691)
N95 respirator masks are recommended for protection against respiratory viruses. Despite passing fit-testing 10% of N95 respirator users encountered breakthroughs with exposure to influenza virus compared ...

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