Takashita E, et al. Detection of influenza A(H3N2) viruses exhibiting reduced susceptibility to the novel cap-dependent endonuclease inhibitor baloxavir in Japan, December 2018. Euro Surveill. 2019 Jan;24(3).. Abstract
submitted by kickingbird at Jan, 26, 2019 from Euro Surveill. 2019 Jan;24(3). (via https://www.ncbi.nlm.nih.gov/pubmed/30670142)
The novel cap-dependent endonuclease inhibitor baloxavir marboxil was approved for the treatment of influenza virus infection in Japan in February 2018. Two influenza A(H3N2) viruses carrying an I38T substitution ... More S, et al. Long non-coding RNA PSMB8-AS1 regulates influenza virus replication. RNA Biol. 2019 Jan 22. Abstract
submitted by kickingbird at Jan, 26, 2019 from RNA Biol. 2019 Jan 22 (via https://www.ncbi.nlm.nih.gov/pubmed/30669933)
Long non-coding RNAs (lncRNAs) are a new arm of gene regulatory mechanism as discovered by sequencing techniques and follow-up functional studies. There are only few studies on lncRNAs as related to gene ... Koutsakos M, Kedzierska K, Subbarao K. Immune Responses to Avian Influenza Viruses. J Immunol. 2019 Jan 15;202(2):382-391.. Abstract
submitted by kickingbird at Jan, 23, 2019 from J Immunol. 2019 Jan 15;202(2):382-391. (via https://www.ncbi.nlm.nih.gov/pubmed/30617120)
Avian influenza A viruses (IAVs) naturally infect different avian species, and aquatic birds are their natural reservoir. Sporadically, avian IAVs can be transmitted to humans, and some, such as H5N1 and ... Hatayama K, et al. Combined effect of anti-high-mobility group box-1 monoclonal antibody and peramivir against influenza A virus-induced pneumonia in mice. J Med Virol. 2019 Mar;91(3):361-369.. Abstract
submitted by kickingbird at Jan, 23, 2019 from J Med Virol. 2019 Mar;91(3):361-369. (via https://www.ncbi.nlm.nih.gov/pubmed/30281823)
Human pandemic H1N1 2009 influenza virus causes significant morbidity and mortality with severe acute lung injury due to the excessive inflammatory reaction, even with neuraminidase inhibitor use. The ... Zhang J, et al. Role of c-Jun terminal kinase (JNK) activation in influenza A virus-induced autophagy and replication. Virology. 2019 Jan 2;526:1-12.. Abstract
submitted by kickingbird at Jan, 23, 2019 from Virology. 2019 Jan 2;526:1-12. (via https://www.ncbi.nlm.nih.gov/pubmed/30316042)
The non-structural protein 1 (NS1) of different influenza A virus (IAV) strains can differentially regulate the activity of c-Jun terminal kinase (JNK) and PI-3 kinase (PI3K). Whether varying JNK and PI3K ... Yang Y, et al. Comparison between human infections caused by highly and low pathogenic H7N9 avian influenza viruses in Wave Five: clinical and virological findings. J Infect. 2019 Jan 18. Abstract
submitted by kickingbird at Jan, 23, 2019 from J Infect. 2019 Jan 18 (via https://www.ncbi.nlm.nih.gov/pubmed/30664912)
OBJECTIVE: The newly emerged highly pathogenic (HP) H7N9 avian influenza virus during Wave Five has caused 28 human infections, while differences in disease severity between low pathogenic (LP)- and HP-H7N9 ... Ni Luh Putu Indi Dharmayanti, et al. Attenuation of highly pathogenic avian influenza A(H5N1) viruses in Indonesia following the reassortment and acquisition of genes from low pathogenicity avian influenza A virus progenitors. Emerging Microbes & Infections vol 7,147 (2018). Abstract
submitted by kickingbird at Jan, 22, 2019 from Emerging Microbes & Infections vol 7,147 (2018) (via https://www.nature.com/articles/s41426-018-0147-5)
The highly pathogenic avian influenza (HPAI) A(H5N1) virus is endemic in Indonesian poultry and has caused sporadic human infection in Indonesia since 2005. Surveillance of H5N1 viruses in live bird markets ... Cong Chen, Zuliang Liu, Liguo Liu, Yan Xiao, et al. Broad neutralizing activity of a human monoclonal antibody against H7N9 strains from 2013 to 2017. Emerging Microbes & Infections vol 7, 179 (2018). Abstract
submitted by kickingbird at Jan, 22, 2019 from Emerging Microbes & Infections vol 7, 179 (2018) (via https://www.nature.com/articles/s41426-018-0182-2)
H7N9 influenza virus has been circulating among humans for five epidemic waves since it was first isolated in 2013 in China. The recent increase in H7N9 infections during the fifth outbreak in China has ... Liu Y, et al. Cross-lineage protection by human antibodies binding the influenza B hemagglutinin. Nat Commun. 2019 Jan 18;10(1):324.. Abstract
submitted by kickingbird at Jan, 22, 2019 from Nat Commun. 2019 Jan 18;10(1):324. (via https://www.nature.com/articles/s41467-018-08165-y)
Influenza B viruses (IBV) drive a significant proportion of influenza-related hospitalisations yet are understudied compared to influenza A. Current vaccines target the head of the viral hemagglutinin ... Bedford JG, O´Keeffe M, Reading PC, Wakim LM. Rapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection. PLoS One. 2019 Jan 16;14(1):e0210132. Abstract
submitted by kickingbird at Jan, 18, 2019 from PLoS One. 2019 Jan 16;14(1):e0210132 (via https://www.ncbi.nlm.nih.gov/pubmed/30650117)
Interferon-induced transmembrane protein 3 (IFITM3) is a potent antiviral protein that enhances cellular resistance to a variety of pathogens, including influenza virus. Classically defined as an interferon-stimulated ... Liu L, Wang T, Wang M, Tong Q, Sun Y, Pu J, et al. Recombinant turkey herpesvirus expressing H9 hemagglutinin providing protection against H9N2 avian influenza. Virology. 2019 Jan 4;529:7-15. Abstract
submitted by kickingbird at Jan, 16, 2019 from Virology. 2019 Jan 4;529:7-15 (via https://www.ncbi.nlm.nih.gov/pubmed/30641481)
H9N2 avian influenza viruses (AIVs) were prevailing in chickens, causing great economic losses and public health threats. In this study, turkey herpesviruses (HVT) was cloned as an infectious bacterial ... Parra-Rojas C, Messling VV, Hernandez-Vargas EA. Adjuvanted influenza vaccine dynamics. Sci Rep. 2019 Jan 11;9(1):73. Abstract
submitted by kickingbird at Jan, 15, 2019 from Sci Rep. 2019 Jan 11;9(1):73 (via https://www.ncbi.nlm.nih.gov/pubmed/30635599)
Adjuvanted influenza vaccines constitute a key element towards inducing neutralizing antibody responses in populations with reduced responsiveness, such as infants and elderly subjects, as well as in devising ... Li J, et al. MOV10 sequesters the RNP of influenza A virus in the cytoplasm and is antagonized by viral NS1 protein. Biochem J. 2019 Jan 7. Abstract
submitted by kickingbird at Jan, 14, 2019 from Biochem J. 2019 Jan 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30617221)
MOV10 has emerged as an important host antiviral factor. MOV10 not only inhibits various viruses including human immunodeficiency virus type 1, hepatitis C virus and vesicular stomatitis virus, it also ... Qin J, Peng O, Shen X, Gong L, Xue C, Cao Y. Multiple amino acid substitutions involved in the adaption of three avian-origin H7N9 influenza viruses in mice. Virol J. 2019 Jan 8;16(1):3. Abstract
submitted by kickingbird at Jan, 14, 2019 from Virol J. 2019 Jan 8;16(1):3 (via https://www.ncbi.nlm.nih.gov/pubmed/30621708)
BACKGROUND: Avian influenza A H7N9 virus has caused five outbreak waves of human infections in China since 2013 and posed a dual challenge to public health and poultry industry. The number of reported ... Qin C, Li W, Li Q, Yin W, Zhang X, et al. Real-time dissection of dynamic uncoating of individual influenza viruses. Proc Natl Acad Sci U S A. 2019 Jan 9.. Abstract
submitted by kickingbird at Jan, 14, 2019 from Proc Natl Acad Sci U S A. 2019 Jan 9. (via https://www.ncbi.nlm.nih.gov/pubmed/30626642)
Uncoating is an obligatory step in the virus life cycle that serves as an antiviral target. Unfortunately, it is challenging to study viral uncoating due to methodology limitations for detecting this transient ... Lu FS, Hattab MW, Clemente CL, et al. Improved state-level influenza nowcasting in the United States leveraging Internet-based data and network approaches. Nat Commun. 2019 Jan 11;10(1):147. Abstract
submitted by kickingbird at Jan, 14, 2019 from Nat Commun. 2019 Jan 11;10(1):147 (via https://www.ncbi.nlm.nih.gov/pubmed/30635558)
In the presence of health threats, precision public health approaches aim to provide targeted, timely, and population-specific interventions. Accurate surveillance methodologies that can estimate infectious ... Evseev D, Magor KE. Innate Immune Responses to Avian Influenza Viruses in Ducks and Chickens. Vet Sci. 2019 Jan 10;6(1).. Abstract
submitted by kickingbird at Jan, 14, 2019 from Vet Sci. 2019 Jan 10;6(1). (via https://www.ncbi.nlm.nih.gov/pubmed/30634569)
Mallard ducks are important natural hosts of low pathogenic avian influenza (LPAI) viruses and many strains circulate in this reservoir and cause little harm. Some strains can be transmitted to other hosts, ... Lu C, Xing Y, Cai H, Shi Y, Liu J, Huang Y. Identification and analysis of long non-coding RNAs in response to H5N1 influenza viruses in duck (Anas platyrhynchos). BMC Genomics. 2019 Jan 11. Abstract
submitted by kickingbird at Jan, 14, 2019 from BMC Genomics. 2019 Jan 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30634898)
BACKGROUND: Long non-coding RNAs (lncRNAs) are important component of mammalian genomes, where their numbers are even larger than that of protein-coding genes. For example, human (Homo sapiens) (96,308 ... Hao M, et al. The PA Subunit of the Influenza Virus Polymerase Complex Affects Replication and Airborne Transmission of the H9N2 Subtype Avian Influenza Virus. Viruses. 2019 Jan 9;11(1). Abstract
submitted by kickingbird at Jan, 14, 2019 from Viruses. 2019 Jan 9;11(1) (via https://www.ncbi.nlm.nih.gov/pubmed/30634394)
The polymerase acidic (PA) protein is the third subunit of the influenza A virus polymerase. In recent years, studies have shown that PA plays an important role in overcoming the host species barrier and ... Chastagner A, et al. Spatiotemporal Distribution and Evolution of the A/H1N1 2009 Pandemic Influenza Virus in Pigs in France from 2009 to 2017: Identification of a Potential Swine-Specific Lineage. J Virol. 2018 Nov 27;92(24). Abstract
submitted by kickingbird at Jan, 14, 2019 from J Virol. 2018 Nov 27;92(24) (via https://www.ncbi.nlm.nih.gov/pubmed/30258006)
The H1N1 influenza virus responsible for the most recent pandemic in 2009 (H1N1pdm) has spread to swine populations worldwide while it replaced the previous seasonal H1N1 virus in humans. In France, surveillance ... 7528 items, 20/Page, Page[173/377][|<<] [|<] [171] [172] [173] [174] [175] [176] [177] [178] [179] [180] [>|] [>>|] |
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