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2024-5-3 12:14:24
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Amanat F, Meade P, Strohmeier S, Krammer F. Cross-reactive antibodies binding to H4 hemagglutinin protect against a lethal H4N6 influenza virus challenge in the mouse model. Emerg Microbes Infect. 2019;8(1):155-168.  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Emerg Microbes Infect. 2019;8(1):155-168 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2018.1)
Influenza viruses of the H4 subtype are widespread in wild birds, circulate in domestic poultry, readily infect mammals, and tolerate the insertion of a polybasic cleavage site. In addition, serological ...

Bao L, et al. Diverse biological characteristics and varied virulence of H7N9 from Wave 5. Emerg Microbes Infect. 2019;8(1):94-102..  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Emerg Microbes Infect. 2019;8(1):94-102. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2018.1)
There was a substantial increase with infections of H7N9 avian influenza virus (AIV) in humans during Wave 5 (2016-2017). To investigate whether H7N9 had become more infectious/transmissible and pathogenic ...

Schloer S, et al. The clinically licensed antifungal drug itraconazole inhibits influenza virus in vitro and in vivo. Emerg Microbes Infect. 2019;8(1):80-93..  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Emerg Microbes Infect. 2019;8(1):80-93. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2018.1)
Influenza A virus (IAV) is a common pathogen of respiratory disease. The IAV-induced seasonal epidemics and the sporadic pandemics are associated with high morbidity and mortality. Therefore, effective ...

Yao Y, et al. Protection against homo and hetero-subtypic in?uenza A virus by optimized M2e DNA vaccine. Emerg Microbes Infect. 2019;8(1):45-54.  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Emerg Microbes Infect. 2019;8(1):45-54 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2018.1)
Current influenza vaccines provide hemagglutinin strain-specific protection, but rarely provide cross-protection against divergent strains. It is, therefore, particularly important to develop a universal ...

Njifon HLM, et al. Genetic diversity of influenza A(H3N2) viruses in Northern Cameroon during the 2014-2016 influenza seasons. J Med Virol. 2019 Mar 13.  Abstract  
submitted by kickingbird at Mar, 15, 2019 from J Med Virol. 2019 Mar 13 (via https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25456)
In Cameroon, genome characterization of influenza virus has been performed only in the Southern regions meanwhile genetic diversity of this virus varies with respect to locality. The Northern region characterized ...

Fritsch A, Schweiger B, Biere B. Influenza C virus in pre-school children with respiratory infections: retrospective analysis of data from the national influenza surveillance system in Germany, 2012 to 2014. Euro Surveill. 2019 Mar;24(10).  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Euro Surveill. 2019 Mar;24(10) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
IntroductionRecent data on influenza C virus indicate a possible higher clinical impact in specified patient populations than previously thought.AimWe aimed to investigate influenza C virus circulation ...

Wiman ?, et al. Novel influenza A(H1N2) seasonal reassortant identified in a patient sample, Sweden, January 2019. Euro Surveill. 2019 Feb;24(9).  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Euro Surveill. 2019 Feb;24(9) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
In January 2019, a human seasonal reassortant influenza A(H1N2) virus with a novel 7:1 genetic constellation was identified in a 68-year-old female patient with suspected pneumonia. The virus harboured ...

Quan L, Ji C, Ding X, Peng Y, Liu M, Sun J, et al. Cluster-transition determining sites underlying the antigenic evolution of seasonal influenza viruses. Mol Biol Evol. 2019 Mar 9.  Abstract  
submitted by kickingbird at Mar, 14, 2019 from Mol Biol Evol. 2019 Mar 9 (via https://academic.oup.com/mbe/advance-article-abstract/doi/10)
Seasonal influenza viruses undergo frequent mutations on their surface hemagglutinin (HA) proteins to escape the host immune response. In these mutations, a few key amino acid sites are associated with ...

Karunakaran AC, et al. Survivability of Highly Pathogenic Avian Influenza Virus (H5N1) in naturally preened Duck Feathers at different temperatures. Transbound Emerg Dis. 2019 Mar 12..  Abstract  
submitted by kickingbird at Mar, 13, 2019 from Transbound Emerg Dis. 2019 Mar 12. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13148)
Ducks are the "Trojan Horses" for Asian H5N1 avian influenza viruses (AIV) and attain carrier status without displaying overt infection. These birds help in the spread of the virus among the poultry and ...

Marques M, Ramos B, Soares AR, Ribeiro D. Cellular Proteostasis During Influenza A Virus Infection-Friend or Foe?. Cells. 2019 Mar 9;8(3).  Abstract  
submitted by kickingbird at Mar, 13, 2019 from Cells. 2019 Mar 9;8(3) (via https://www.mdpi.com/2073-4409/8/3/228)
In order to efficiently replicate, viruses require precise interactions with host components and often hijack the host cellular machinery for their own benefit. Several mechanisms involved in protein synthesis ...

Ting-Hui-Lin, et al. Improving immunogenicity of influenza virus H7N9 recombinant hemagglutinin for vaccine development. Vaccine. 2019 Mar 22;37(13):1897-1903..  Abstract  
submitted by kickingbird at Mar, 13, 2019 from Vaccine. 2019 Mar 22;37(13):1897-1903. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
Human infections of novel avian influenza A virus (H7N9) emerged in early 2013 and caused about 40% case-fatality through 2017. Therefore, development of influenza H7N9 vaccines is critical for pandemic ...

Cueno ME, et al. Structural significance of residues 158-160 in the H3N2 hemagglutnin globular head: A computational study with implications in viral evolution and infection. J Mol Graph Model. 2019 Feb 25;89:33-40..  Abstract  
submitted by kickingbird at Mar, 10, 2019 from J Mol Graph Model. 2019 Feb 25;89:33-40. (via https://www.sciencedirect.com/science/article/pii/S109332631)
Influenza A H3N2 has been linked to annual outbreaks within the human population attributable to continuous structural changes. H3N2 HA contains well identified antigenic sites and receptor-binding sites ...

Bakri M, Samuh M, Azzeh M. Molecular epidemiology survey and characterization of human influenza A viruses circulating among Palestinians in East Jerusalem and the West Bank in 2015. PLoS One. 2019 Mar 8;14(3):e0213290.  Abstract  
submitted by kickingbird at Mar, 10, 2019 from PLoS One. 2019 Mar 8;14(3):e0213290 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Frequent typing and molecular characterization of influenza A (IAV) strains are crucial for the identification of circulating subtypes and for the selection of the subtypes' lineages to be included in ...

Liu J, Zhou L, Lv J, Zou Y, Wang T. Two novel reassortant H11N8 avian influenza viruses occur in wild birds found in East Dongting Lake, China. Arch Virol. 2019 Mar 8.  Abstract  
submitted by kickingbird at Mar, 10, 2019 from Arch Virol. 2019 Mar 8 (via https://link.springer.com/article/10.1007%2Fs00705-019-04168)
During the surveillance of avian influenza viruses in East Dongting Lake, China (2014-2015), two H11N8 avian influenza viruses were detected in the bean goose (Anser fabalis) and the falcated teal (Anas ...

Michalak P, et al. Secondary structure of the segment 5 genomic RNA of influenza A virus and its application for designing antisense oligonucleotides. Sci Rep. 2019 Mar 7;9(1):3801.  Abstract  
submitted by kickingbird at Mar, 10, 2019 from Sci Rep. 2019 Mar 7;9(1):3801 (via https://www.nature.com/articles/s41598-019-40443-7)
Influenza virus causes seasonal epidemics and dangerous pandemic outbreaks. It is a single stranded (-)RNA virus with a segmented genome. Eight segments of genomic viral RNA (vRNA) form the virion, which ...

van Dongen MJP, et al. A small-molecule fusion inhibitor of influenza virus is orally active in mice. Science. 2019 Mar 8;363(6431)..  Abstract  
submitted by kickingbird at Mar, 10, 2019 from Science. 2019 Mar 8;363(6431). (via http://science.sciencemag.org/content/363/6431/eaar6221)
Recent characterization of broadly neutralizing antibodies (bnAbs) against influenza virus identified the conserved hemagglutinin (HA) stem as a target for development of universal vaccines and therapeutics. ...

Adisasmito W, et al. Surveillance and characterisation of influenza viruses among patients with influenza-like illness in Bali, Indonesia, July 2010~June 2014. BMC Infect Dis. 2019 Mar 7;19(1):231.  Abstract  
submitted by kickingbird at Mar, 10, 2019 from BMC Infect Dis. 2019 Mar 7;19(1):231 (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
BACKGROUND: Although Indonesia has high fatality rate of human A/H5N1 cases, epidemiological and clinical data on influenza virus circulation among humans has been limited. Within Indonesia, Bali province ...

Daoud A, et al. Pulmonary complications of influenza infection: a targeted narrative review. Postgrad Med. 2019 Mar 8..  Abstract  
submitted by kickingbird at Mar, 10, 2019 from Postgrad Med. 2019 Mar 8. (via https://www.tandfonline.com/doi/abs/10.1080/00325481.2019.15)
Severe influenza infection represents a leading cause of global morbidity and mortality. Several clinical syndromes that involve a number of organs may be associated with Influenza infection. However, ...

Jacqueline M. Nolting Scott D. Scheer Andrew S.. Perceptions and attitudes of swine exhibitors towards recommendations for reducing zoonotic transmission of influenza A viruses. Zoonoses and Public Health 06 Mar 2019.  Abstract  
submitted by kickingbird at Mar, 10, 2019 from Zoonoses and Public Health 06 Mar 2019 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/zph.12574)
Since 2011, there have been 468 cases of variant influenza A virus (IAV) reported in the United States, many of which were associated with youth swine exhibition. In an effort to mitigate risk associated ...

Mandala VS, Liao SY, Gelenter MD, Hong M. The Transmembrane Conformation of the Influenza B Virus M2 Protein in Lipid Bilayers. Sci Rep. 2019 Mar 6;9(1):3725..  Abstract  
submitted by kickingbird at Mar, 10, 2019 from Sci Rep. 2019 Mar 6;9(1):3725. (via https://www.nature.com/articles/s41598-019-40217-1)
Influenza A and B viruses cause seasonal flu epidemics. The M2 protein of influenza B (BM2) is a membrane-embedded tetrameric proton channel that is essential for the viral lifecycle. BM2 is a functional ...

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