Rane CK, et al. Development of solitary chemosensory cells in the distal lung after severe influenza injury. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 25.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Am J Physiol Lung Cell Mol Physiol. 2019 Mar 25. (via https://www.physiology.org/doi/abs/10.1152/ajplung.00032.201)
H1N1 influenza virus infection induces dramatic and permanent alveolar remodeling mediated by p63+ progenitor cell expansion in both mice and some patients with acute respiratory distress syndrome. This ... Magnen M, et al. Tissue kallikrein (KLK1) regulates alveolar macrophage apoptosis early in influenza virus infection. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 25.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Am J Physiol Lung Cell Mol Physiol. 2019 Mar 25. (via https://www.physiology.org/doi/abs/10.1152/ajplung.00379.201)
Host cell proteases are involved in influenza pathogenesis. We examined the role of tissue kallikrein 1 (KLK1) by comparing wild-type (WT) and KLK1-deficient mice infected with influenza H3N2 virus. Levels ... Derrar F, et al. Influenza surveillance during the 2009-10, 2010-11, 2011-12 and 2012-13 seasons in algeria. J Med Virol. 2019 Mar 25.. Abstract
submitted by kickingbird at Mar, 26, 2019 from J Med Virol. 2019 Mar 25. (via https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25469)
We report the activity and circulation of influenza viruses in Algeria during four influenza seasons, from a national surveillance study carried out from 2009-2010 to 2012-2013. A total of 2,766 samples ... She YM, Li X, Cyr TD. Remarkable Structural Diversity of N-Glycan Sulfation on Influenza Vaccines. Anal Chem. 2019 Mar 25.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Anal Chem. 2019 Mar 25. (via https://pubs.acs.org.ccindex.cn/doi/10.1021/acs.analchem.8b0)
Sulfated N-glycans are biologically important structures derived from enzymatically post-glycosylational modifications of glycoproteins in many therapeutic biologics. The high-throughput analysis of sulfated ... Walaza S, et al. The Impact of Influenza and Tuberculosis Interaction on Mortality Among Individuals Aged ≥15 Years Hospitalized With Severe Respiratory Illness in South Africa, 2010-2016.. Open Forum Infect Dis. 2019 Mar 19;6(3):ofz020.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Open Forum Infect Dis. 2019 Mar 19;6(3):ofz020. (via https://academic.oup.com/ofid/article/6/3/ofz020/5393643)
Background: Data on the prevalence and impact of influenza-tuberculosis coinfection on clinical outcomes from high-HIV and -tuberculosis burden settings are limited. We explored the impact of influenza ... H?fer CT, et al. Structural determinants of the interaction between influenza a virus matrix protein M1 and lipid membranes. Biochim Biophys Acta Biomembr. 2019 Mar 19. Abstract
submitted by kickingbird at Mar, 26, 2019 from Biochim Biophys Acta Biomembr. 2019 Mar 19 (via https://www.sciencedirect.com/science/article/pii/S000527361)
Influenza A virus is a pathogen responsible for severe seasonal epidemics threatening human and animal populations every year. One of the ten proteins encoded by the viral genome, the matrix protein M1, ... Stepanova EA, et al. Amino Acid Substitutions N123D and N149D in Hemagglutinin Molecule Enhance Immunigenicity of Live Attenuated Influenza H7N9 Vaccine Strain in Experiment. Bull Exp Biol Med. 2019 Mar 22.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Bull Exp Biol Med. 2019 Mar 22. (via https://link.springer.com/article/10.1007%2Fs10517-019-04407)
We compared three cold-adapted live attenuated influenza vaccine strains prepared by reverse genetics methods on the basis of master donor virus A/Leningrad/134/17/57 and influenza H7N9 strains A/Anhui/1/2013 ... Chen S, et al. Predicting Temporal Propagation of Seasonal Influenza Using Improved Gaussian Process Model. J Biomed Inform. 2019 Mar 21:103144.. Abstract
submitted by kickingbird at Mar, 26, 2019 from J Biomed Inform. 2019 Mar 21:103144. (via https://www.sciencedirect.com/science/article/pii/S153204641)
Influenza rapidly spreads in seasonal epidemics and imposes a considerable economic burden on hospitals and other healthcare costs. Thus, predicting the propagation of influenza accurately is crucial in ... Abubakar A, et al. Pandemic influenza preparedness (PIP) framework: Progress challenges in improving influenza preparedness response capacities in the Eastern Mediterranean Region, 2014-2017. J Infect Public Health. 2019 Mar 21. Abstract
submitted by kickingbird at Mar, 26, 2019 from J Infect Public Health. 2019 Mar 21 (via https://www.sciencedirect.com/science/article/pii/S187603411)
Influenza viruses with pandemic potential have been detected in humans in the Eastern Mediterranean Region. The Pandemic Influenza Preparedness (PIP) Framework aims to improve the sharing of influenza ... Ross TM, et al. A computationally designed H5 antigen shows immunological breadth of coverage and protects against drifting avian strains. Vaccine. 2019 Mar 21.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Vaccine. 2019 Mar 21. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
Since the first identification of the H5N1 Goose/Guangdong lineage in 1996, this highly pathogenic avian influenza virus has spread worldwide, becoming endemic in domestic poultry. Sporadic transmission ... Fujioka Y, et al. A peptide derived from phosphoinositide 3-kinase inhibits endocytosis and influenza virus infection. Cell Struct Funct. 2019 Mar 21.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Cell Struct Funct. 2019 Mar 21. (via https://www.jstage.jst.go.jp/article/csf/advpub/0/advpub_190)
Endocytosis mediates the internalization and ingestion of a variety of endogenous or exogenous substances, including virus particles, under the control of intracellular signaling pathways. We have previously ... Kannan S, Shankar R, Kolandaivel P. Insights into structural and inhibitory mechanisms of low pH-induced conformational change of influenza HA2 protein: a computational approach. J Mol Model. 2019 Mar 23;25(4):99. Abstract
submitted by kickingbird at Mar, 26, 2019 from J Mol Model. 2019 Mar 23;25(4):99 (via https://link.springer.com/article/10.1007%2Fs00894-019-3982-)
Though oseltamivir and zanamivir are the active anti-influenza drugs, the emergence of different strains of influenza A virus with mutations creates drug-resistance to these drugs. Therefore, it is essential ... Lindert K, Leav B, Heijnen E, Barrett J, Nicolay U. MF59-Adjuvanted Seasonal Trivalent Influenza Vaccine: Pooled Analysis of Safety in Older Adults ≥65 Years of Age. Int J Infect Dis. 2019 Mar 20.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Int J Infect Dis. 2019 Mar 20. (via https://www.ijidonline.com/article/S1201-9712(19)30149-3/pdf)
OBJECTIVE: To assess the long-term safety of MF59-adjuvanted trivalent influenza vaccine (aIIV3; Fluad?) in adults ≥65 years of age.METHODS: Data from 36 primary vaccination and 7 re-vaccination Phase ... Akand EH, Downard KM. Mechanisms of Antiviral Resistance in Influenza Neuraminidase Revealed by a Mass Spectrometry Based Phylonumerics Approach. Mol Phylogenet Evol. 2019 Mar 20. Abstract
submitted by kickingbird at Mar, 26, 2019 from Mol Phylogenet Evol. 2019 Mar 20 (via https://www.sciencedirect.com/science/article/pii/S105579031)
A mass based phylonumerics approach is shown to be able to investigate the origins of the emergence of antiviral resistance mutations in influenza neuraminidase through a global view of mutational trends. ... Yamamoto Y, et al. Peptides with the multibasic cleavage site of the hemagglutinin from highly pathogenic influenza viruses act as cell-penetrating via binding to heparan sulfate and neuropilins. Biochem Biophys Res Commun. 2019 Mar 20. Abstract
submitted by kickingbird at Mar, 26, 2019 from Biochem Biophys Res Commun. 2019 Mar 20 (via https://www.sciencedirect.com/science/article/pii/S0006291X1)
Cell-penetrating peptides (CPPs) show promise as an attractive delivery vehicle for therapeutic molecules-including nucleic acids, peptides, proteins, and even particulates-into several cell types. It ... Jiang W, et al. Prevalence of H7N9 subtype avian influenza viruses in poultry in China, 2013-2018. Transbound Emerg Dis. 2019 Mar 23. Abstract
submitted by kickingbird at Mar, 26, 2019 from Transbound Emerg Dis. 2019 Mar 23 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13183)
H7N9 subtype avian influenza viruses (AIV) circulating in China over recent years have had an enormous impact on public health and economy. During the period between November 2016 and April 2017, an increase ... Cherdantseva LA, et al. Death Mechanisms of Pulmonary Alveolocytes in Mice Infected with Influenza Viruses A/H1N1/California/04/2009 and A/H5N1/Goose/Krasnoozerskoye/627/05. Bull Exp Biol Med. 2019 Mar 22. Abstract
submitted by kickingbird at Mar, 26, 2019 from Bull Exp Biol Med. 2019 Mar 22 (via https://link.springer.com/article/10.1007%2Fs10517-019-04408)
In CBA mice infected with influenza viruses A/H1N1/California/04/2009 and A/H5N1/Goose/Krasnoozerskoye/627/05 in a dose of 10 MLD50, the mechanisms of death of pulmonary alveolocytes over 10 postinfection ... Amarelle L, et al. Cardiac glycosides decrease influenza virus replication by inhibiting cell protein translational machinery. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 20. Abstract
submitted by kickingbird at Mar, 25, 2019 from Am J Physiol Lung Cell Mol Physiol. 2019 Mar 20 (via https://www.physiology.org/doi/abs/10.1152/ajplung.00173.201)
Cardiac glycosides (CG) are used primarily for cardiac failure and have been reported to have other effects, including inhibition of viral replication. Here we set out to study mechanisms by which CG as ... Puchades C, et al. Epitope mapping of diverse influenza Hemagglutinin drug candidates using HDX-MS. Sci Rep. 2019 Mar 18;9(1):4735. Abstract
submitted by kickingbird at Mar, 25, 2019 from Sci Rep. 2019 Mar 18;9(1):4735 (via https://www.nature.com/articles/s41598-019-41179-0)
Epitope characterization is critical for elucidating the mechanism of action of drug candidates. However, traditional high-resolution epitope mapping techniques are not well suited for screening numerous ... Oishi K, Yamayoshi S, Kawaoka Y. Identification of Amino Acid Residues in Influenza A Virus PA-X That Contribute to Enhanced Shutoff Activity. Front Microbiol. 2019 Mar 6;10:432.. Abstract
submitted by kickingbird at Mar, 25, 2019 from Front Microbiol. 2019 Mar 6;10:432. (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0043)
The influenza virus protein PA-X modulates the host immune responses and viral pathogenicity through suppression of host protein expression. The endonuclease active site in the N-terminal region, the basic ... 7540 items, 20/Page, Page[161/377][|<<] [|<] [161] [162] [163] [164] [165] [166] [167] [168] [169] [170] [>|] [>>|] |
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