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2024-5-21 6:46:18
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Hirst JC, Hutchinson EC. Single-particle measurements of filamentous influenza virions reveal damage induced by freezing. J Gen Virol. 2019 Sep 25..  Abstract  
submitted by kickingbird at Sep, 27, 2019 from J Gen Virol. 2019 Sep 25. (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Clinical isolates of influenza virus produce pleiomorphic virions, ranging from small spheres to elongated filaments. The filaments are seemingly adaptive in natural infections, but their basic functional ...

Sah P, et al. Future epidemiological and economic impacts of universal influenza vaccines. PNAS 2019 Sep 23.  Abstract  
submitted by kickingbird at Sep, 26, 2019 from PNAS 2019 Sep 23 (via https://www.pnas.org/content/early/2019/09/17/1909613116)
The efficacy of influenza vaccines, currently at 44%, is limited by the rapid antigenic evolution of the virus and a manufacturing process that can lead to vaccine mismatch. The National Institute of Allergy ...

Bergervoet SA, et al. Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006~2016. Sci Rep. 2019 Sep 23;9(1):13681.  Abstract  
submitted by kickingbird at Sep, 26, 2019 from Sci Rep. 2019 Sep 23;9(1):13681 (via https://www.nature.com/articles/s41598-019-50170-8)
In this study, we explore the circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands. Surveillance data collected between 2006 and 2016 was used to evaluate ...

Ramage W, et al. Cross-Reactive and Lineage-Specific Single Domain Antibodies against Influenza B Hemagglutinin. Antibodies (Basel). 2019 Feb 10;8(1).  Abstract  
submitted by kickingbird at Sep, 25, 2019 from Antibodies (Basel). 2019 Feb 10;8(1) (via https://www.mdpi.com/2073-4468/8/1/14)
Influenza B virus (IBV) circulates in the human population and causes considerable disease burden worldwide, each year. Current IBV vaccines can struggle to mount an effective cross-reactive immune response, ...

Patel H, Kukol A. Prediction of ligands to universally conserved binding sites of the influenza a virus nuclear export protein. Virology. 2019 Aug 14;537:97-103.  Abstract  
submitted by kickingbird at Sep, 24, 2019 from Virology. 2019 Aug 14;537:97-103 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The nuclear export protein (NEP) of the influenza A virus exports viral ribonucleoproteins to the host cell cytoplasm following nuclear transcription. In this work conservation analysis of 3000 protein ...

Rojas-Osornio SA, et al. Immunity to influenza: Impact of obesity. Obes Res Clin Pract. 2019 Sep 18..  Abstract  
submitted by kickingbird at Sep, 24, 2019 from Obes Res Clin Pract. 2019 Sep 18. (via https://www.sciencedirect.com/science/article/abs/pii/S18714)
Obesity is a health concern that is recognized as a critical factor for vulnerability to influenza A/pdmH1N1 virus infection, with epidemiological and clinical impacts. In humans, obesity induces disturbances ...

Chesnokov A, et al. Replicative fitness of seasonal influenza A viruses with decreased susceptibility to baloxavir. J Infect Dis. 2019 Sep 21..  Abstract  
submitted by kickingbird at Sep, 23, 2019 from J Infect Dis. 2019 Sep 21. (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
Susceptibility of influenza A viruses to baloxavir can be affected by changes at amino acid residue 38 in polymerase acidic (PA) protein. Information on replicative fitness of PA-I38-substituted viruses ...

Bekking C, et al. Evaluation of bioaerosol samplers for the detection and quantification of influenza virus from artificial aerosols and influenza virus-infected ferrets. Influenza Other Respir Viruses. 2019 Sep 21.  Abstract  
submitted by kickingbird at Sep, 23, 2019 from Influenza Other Respir Viruses. 2019 Sep 21 (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12678)
BACKGROUND: Bioaerosol sampling devices are necessary for the characterization of infectious bioaerosols emitted by naturally-infected hosts with acute respiratory virus infections. Assessment of these ...

Vijaykrishna D, Deng Y, Grau ML, et al. Emergence of Influenza A(H7N4) Virus, Cambodia. Emerg Infect Dis. 2019;25(10):1988-1991.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019;25(10):1988-1991 (via https://wwwnc.cdc.gov/eid/article/25/10/19-0506_article)
Active surveillance in high-risk sites in Cambodia has identified multiple low-pathogenicity influenza A(H7) viruses, mainly in ducks. None fall within the A/Anhui/1/2013(H7N9) lineage; however, some A(H7) ...

Zhou L, Li Q, Uyeki TM. Estimated Incubation Period and Serial Interval for Human-to-Human Influenza A(H7N9) Virus Transmission. Emerg Infect Dis. 2019;25(10):1982-1983.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019;25(10):1982-1983 (via https://wwwnc.cdc.gov/eid/article/25/10/19-0117_article)
We estimated the incubation period and serial interval for human-to-human transmitted avian influenza A(H7N9) virus infection using case-patient clusters from epidemics in China during 201~2017. The median ...

Chastagner A, Enouf V, Peroz D, et al. Bidirectional Human-Swine Transmission of Seasonal Influenza A(H1N1)pdm09 Virus in Pig Herd, France, 2018. Emerg Infect Dis. 2019;25(10):1940-1943.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019;25(10):1940-1943 (via https://wwwnc.cdc.gov/eid/article/25/10/19-0068_article)
In 2018, a veterinarian became sick shortly after swabbing sows exhibiting respiratory syndrome on a farm in France. Epidemiologic data and genetic analyses revealed consecutive human-to-swine and swine-to-human ...

Wille M, Lisovski S, Risely A, et al. Serologic Evidence of Exposure to Highly Pathogenic Avian Influenza H5 Viruses in Migratory Shorebirds, Australia. Emerg Infect Dis. 2019;25(10):1903-1910.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019;25(10):1903-1910 (via https://wwwnc.cdc.gov/eid/article/25/10/19-0699_article)
Highly pathogenic avian influenza (HPAI) H5Nx viruses of the goose/Guangdong/96 lineage continue to cause outbreaks in poultry and wild birds globally. Shorebirds, known reservoirs of avian influenza viruses, ...

Weese J, Anderson M, Berhane Y, et al. Emergence and Containment of Canine Influenza Virus A(H3N2), Ontario, Canada, 2017~2018. Emerg Infect Dis. 2019;25(10):1810-1816.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019;25(10):1810-1816 (via https://wwwnc.cdc.gov/eid/article/25/10/19-0196_article)
Canine influenza virus (CIV) A(H3N2) was identified in 104 dogs in Ontario, Canada, during December 28, 2017~October 30, 2018, in distinct epidemiologic clusters. High morbidity rates occurred within groups ...

Bai R, et al. Antigenic Variation of Avian Influenza A(H5N6) Viruses, Guangdong Province, China, 2014-2018. Emerg Infect Dis. 2019 Oct;25(10):1932-1945.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019 Oct;25(10):1932-1945 (via https://wwwnc.cdc.gov/eid/article/25/10/19-0274_article)
Market surveillance showed continuing circulation of avian influenza A(H5N6) virus in live poultry markets in Guangdong Province in 2017, despite compulsory vaccination for avian influenza A(H5Nx) and ...

Pohlmann A, et al. Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018. Emerg Infect Dis. 2019 Oct;25(10):1973-1976..  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019 Oct;25(10):1973-1976. (via https://wwwnc.cdc.gov/eid/article/25/10/18-1931_article)
We genetically characterized highly pathogenic avian influenza virus A(H5N6) clade 2.3.4.4b isolates found in Germany in 2017-2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ...

Sheng T, Sun Y, Sun J, Prinz RA, Peng D, et al. Role of TGF-β-activated kinase 1 (TAK1) activation in H5N1 influenza A virus-induced c-Jun terminal kinase activation and virus replication. Virology. 2019 Sep 10;537:263-271.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Virology. 2019 Sep 10;537:263-271 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Activation of c-Jun terminal kinase (JNK) by the nonstructural protein 1 (NS1) of the H5N1 subtype of influenza A virus (IAV) plays an important role in inducing autophagy and virus replication. However, ...

Hirotsu N, et al. Baloxavir marboxil in Japanese pediatric patients with influenza: safety and clinical and virologic outcomes. Clin Infect Dis. 2019 Sep 20..  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Clin Infect Dis. 2019 Sep 20. (via https://academic.oup.com/cid/advance-article/doi/10.1093/cid)
BACKGROUND: We assessed the safety and effectiveness of baloxavir marboxil administration in Japanese children with influenza.METHODS: This open-label study administered one weigth-adjusted dose of baloxavir ...

Yu Z, Cheng K, He H, Wu J. A novel reassortant influenza A (H1N1) virus infection in swine in Shandong Province, eastern China. Transbound Emerg Dis. 2019 Sep 19..  Abstract  
submitted by kickingbird at Sep, 21, 2019 from Transbound Emerg Dis. 2019 Sep 19. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13360)
Influenza A (H1N1) viruses are distributed worldwide and pose a threat to public health. Swine, as a natural host and mixing vessel of influenza A (H1N1) virus, play a critical role in the transmission ...

Blackburn RM, et al. Nosocomial transmission of influenza: A retrospective cross-sectional study using next generation sequencing at a hospital in England (2012-2014). Influenza Other Respir Viruses. 2019 Sep 19.  Abstract  
submitted by kickingbird at Sep, 21, 2019 from Influenza Other Respir Viruses. 2019 Sep 19 (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12679)
BACKGROUND: The extent of transmission of influenza in hospital settings is poorly understood. Next generation sequencing may improve this by providing information on the genetic relatedness of viral strains.OBJECTIVES: ...

Gao S, Zhang W, Lu C, Cao M, Cen S, Peng Y, Deng T. Identification of a type-specific promoter element that differentiates between influenza A and B viruses. J Virol. 2019 Sep 18.  Abstract  
submitted by kickingbird at Sep, 21, 2019 from J Virol. 2019 Sep 18 (via https://jvi.asm.org/content/early/2019/09/12/JVI.01164-19)
Type A and type B influenza viruses (FluA and FluB) are two major human pathogens that share common structural and functional features. FluA and FluB could reassort within each type but never between them. ...

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