David C. Brice, etc.,al. Immunogenicity and efficacy of commercial poultry avian influenza vaccines against HPAI A(H5N1) clade 2.3.4.4b viruses in Mexico. Virology. Abstract
submitted by kickingbird at Nov, 30, 2025 from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The high-pathogenicity avian influenza A(H5N1) viruses of clade 2.3.4.4b have been detected in domestic poultry and wild birds in Mexico. Vaccination with H5 vaccines has been implemented as a complementary ... Nayduch, D., Scroggs, S.L., Shults, P. et al. Detection of H5N1 highly pathogenic avian influenza virus RNA in filth flies collected from California farms in 2024. Sci Rep (2025). Abstract
submitted by kickingbird at Nov, 29, 2025 from Sci Rep (2025) (via https://www.nature.com/articles/s41598-025-29856-9)
The emergence of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b in U.S. dairy cattle highlights the urgent need to understand transmission dynamics within and among farms. House flies (Musca ... Zhang M, Qin L, Li Z, Chen J, Tong J, Ding X, Li H. Dominant substitutions underlying the antigenic evolution of H5 influenza virus. Nat Commun. 2025 Nov 28;16(1):10708. Abstract
submitted by kickingbird at Nov, 29, 2025 from Nat Commun. 2025 Nov 28;16(1):10708 (via https://www.nature.com/articles/s41467-025-65730-y)
Highly pathogenic avian influenza (HPAI) H5 viruses have recently been documented in mammals including humans, posing a major threat to global public health. To prevent a potential H5 pandemic, it is critical ... Pollett SD, Hone E, Richard SA, Schmidt K, Simons. The Epidemiology, Phylogeny, and Strain Antigenicity of an Influenza A/H3N2 Virus Outbreak Among Vaccinated US Navy Midshipmen. Influenza Other Respir Viruses. 2025 Dec;19(12):e7. Abstract
submitted by kickingbird at Nov, 29, 2025 from Influenza Other Respir Viruses. 2025 Dec;19(12):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70184)
We performed epidemiological, genetic, and antigenic characterization of an influenza A/H3N2 outbreak in a congregate setting of young adults with high vaccination rates. We noted substantial duty-days ... Huang A, Liu Y, Li Y, Yin Z, Huo S, Wang J, Yang Z. Recombinant expression and functional characterization of influenza A virus neuraminidase in a mammalian cell system. Front Microbiol. 2025 Nov 12;16:1729393. Abstract
submitted by kickingbird at Nov, 29, 2025 from Front Microbiol. 2025 Nov 12;16:1729393 (via https://www.frontiersin.org/journals/microbiology/articles/1)
The soluble and functional expression of influenza A virus neuraminidase (NA) remains a major challenge due to its membrane-associated nature and structural complexity. In this study, we established a ... Hongying Chen, etc.,al. [preprint]NSUN2-dependent 5-methylcytosine Modification Regulates Influenza A virus Gene Expression and Genomic Packaging. https://doi.org/10.1101/2025.11.26.690652. Abstract
submitted by kickingbird at Nov, 28, 2025 from https://doi.org/10.1101/2025.11.26.690652 (via https://www.biorxiv.org/content/10.1101/2025.11.26.690652v1)
Emerging evidence indicates that methyltransferase NSUN2 catalyzes 5-methylcytosine (m5C) modifications on various viral RNAs and plays important roles in viral biology. However, the regulatory roles of ... Christopher Ruis, etc.,al. [preprint]Mutational spectra reveal influenza virus transmission routes and adaptation. https://doi.org/10.1101/2025.11.26.690773. Abstract
submitted by kickingbird at Nov, 28, 2025 from https://doi.org/10.1101/2025.11.26.690773 (via https://www.biorxiv.org/content/10.1101/2025.11.26.690773v1)
Influenza A virus remains a major cause of morbidity and mortality in humans and animals with pandemic potential. While control of outbreaks and spillover events remains a key health priority, the transmission ... Wu Y, Long Y, Yang X, Du X, Du X, Zahan N, Deng Z,. Harnessing a Surface Water-Based Multifaceted Approach to Combat Zoonotic Viruses: A Rural Perspective from Bangladesh and China. Microorganisms. 2025; 13(11):2526. Abstract
submitted by kickingbird at Nov, 28, 2025 from Microorganisms. 2025; 13(11):2526 (via https://www.mdpi.com/2076-2607/13/11/2526)
Rural tropical regions face escalating threats from zoonotic AIV and dengue virus but lack sewered infrastructure for conventional wastewater surveillance. We implemented surface water-based surveillance ... Turnbull ML, Wang Y, Clare S, Lieber G, Williams S. Avian-origin influenza A viruses tolerate elevated pyrexic temperatures in mammals. Science. 2025 Nov 27;390(6776):eadq4691. Abstract
submitted by kickingbird at Nov, 28, 2025 from Science. 2025 Nov 27;390(6776):eadq4691 (via https://www.science.org/doi/10.1126/science.adq4691)
Host body temperature can define a virus's replicative profile-influenza A viruses (IAVs) adapted to 40° to 42°C in birds are less temperature sensitive in vitro compared with human isolates adapted to ... Guo J, Jung B, Yoon SW, Liu Y, Feng Z, Yeom M, Na. Negative regulation of reassortant canine influenza virus replication and key site identification in porcine and ferret bronchial epithelial cell lines. Virulence. 2025 Nov 27:2595767. Abstract
submitted by kickingbird at Nov, 28, 2025 from Virulence. 2025 Nov 27:2595767 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2025.2)
The segmented nature and high mutability of the influenza virus RNA genome facilitate rapid mutation and reassortment, allowing the virus to breach host barriers and migrate between different species, ... Wu M, Wang M, Zeng X, Zhang K, Wang M, Xu G, Wang. HA protein acetylation modulates replication, pathogenicity, and immunogenicity of influenza virus and facilitates live-attenuated vaccine design. Emerg Microbes Infect. 2025 Nov 27:2595799. Abstract
submitted by kickingbird at Nov, 28, 2025 from Emerg Microbes Infect. 2025 Nov 27:2595799 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Lysine acetylation, a form of protein post-translational modifications (PTM), is known to play crucial roles in regulating cellular and physiological processes. In this study, for the first time, lysine ... Xiong W, Yin H, Gao L, Liang S. Global Trends in Influenza and Meningitis Research: A Comprehensive Bibliometric and Visualization Analysis (1980-2024). J Multidiscip Healthc. 2025 Nov 21;18:7609-7625. Abstract
submitted by kickingbird at Nov, 28, 2025 from J Multidiscip Healthc. 2025 Nov 21;18:7609-7625 (via https://www.dovepress.com/global-trends-in-influenza-and-men)
Background: Influenza and meningitis are interconnected through shared epidemiological patterns and complications, with influenza often leading to bacterial meningitis by compromising host immunity. This ... Anselmo Vasconcelos Rivetti Jr, etc.,al. Genomic Diversity and Reassortment of Highly Pathogenic Avian Influenza A/H5N1 Virus (Clade 2.3.4.4b) in Brazil: Evidence of Multiple Introductions and Intra-Epidemic Reassortment in 2025. Virology. Abstract
submitted by kickingbird at Nov, 28, 2025 from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Highly pathogenic avian influenza (HPAI) A/H5N1, clade 2.3.4.4b, has spread globally, with the first outbreak in a commercial poultry farm in Brazil reported in 2025. This study aimed to genetically characterize ... Chang Li. Genetic evolutionary dynamics and interspecies transmission risk of H9N2 subtype of avian influenza viruses. Animals and Zoonoses. Abstract
submitted by kickingbird at Nov, 28, 2025 from Animals and Zoonoses (via https://www.sciencedirect.com/science/article/pii/S295024892)
Since its initial isolation from a turkey flock in Wisconsin, USA, in 1966, the H9N2 subtype of avian influenza virus (AIV) has emerged as a significant threat to the global poultry industry and human ... Shen W, Xu J, Chen Z, Wei Y, Wang Q, Wang X, Zhang. Broad-spectrum inhibition of influenza A virus replication by blocking the nuclear export of viral ribonucleoprotein complexes. J Virol 0:e01478-25. Abstract
submitted by kickingbird at Nov, 28, 2025 from J Virol 0:e01478-25 (via https://journals.asm.org/doi/10.1128/jvi.01478-25)
Influenza A virus (IAV) remains a major threat to global health. The emergence of IAV strains resistant to commonly used anti-influenza medicines has made the need for novel broad-spectrum antiviral agents ... Cargnin Faccin, F., Gay, L.C., Regmi, D. et al. Sequential aerosol and oral immunization with a bivalent H9N2/H5N2 vaccine protects against H5N1 and H9N2 avian influenza challenges. npj Vaccines (2025). Abstract
submitted by kickingbird at Nov, 28, 2025 from npj Vaccines (2025) (via https://link.springer.com/article/10.1038/s41541-025-01325-4)
Avian influenza continues to be a major threat to poultry and public health. This study investigated the efficacy of a bivalent H9N2/H5N2 modified live virus (MLV) vaccine delivered through a sequential ... Gopal AB, Lv H, Pholcharee T, Ouyang WO, Teo QW, L. Characterization of two non-competing antibodies to influenza H3N2 hemagglutinin stem reveals its evolving antigenicity. Nat Commun. 2025 Nov 26;16(1):10557. Abstract
submitted by kickingbird at Nov, 27, 2025 from Nat Commun. 2025 Nov 26;16(1):10557 (via https://www.nature.com/articles/s41467-025-65595-1)
The conserved stem domain of influenza hemagglutinin (HA), which is classified into group 1 and group 2, is a target of broadly neutralizing antibodies. While many group 1 HA stem antibodies have been ... Shichinohe S, Hiono T, Itoh Y, Takada K, Kida Y, W. Characterization of H5N1 high pathogenicity avian influenza virus belonging to clade 2.3.4.4b isolated from Ezo red fox in Japan in a mouse model. Microbiol Spectr. 2025 Nov 26:e0109725. Abstract
submitted by kickingbird at Nov, 27, 2025 from Microbiol Spectr. 2025 Nov 26:e0109725 (via https://journals.asm.org/doi/10.1128/spectrum.01097-25)
H5N1 high pathogenicity avian influenza virus (HPAIV) has spread in wild birds and poultry worldwide. H5N1 HPAIV belonging to the currently predominant clade 2.3.4.4b has infected not only birds but also ... ZHOU Yangzi, LIN Yukun, LI Xiyan, WANG Dayan, YAN. Epidemiological and Genetic Characterization of Canine Influenza Virus Outbreaks at a Dog Breeding Facility in Shangqiu, Henan Province, China, During the Winter of 2024-2025. CHINESE JOURNAL OF VIROLOGY (2025). Abstract
submitted by kickingbird at Nov, 27, 2025 from CHINESE JOURNAL OF VIROLOGY (2025) (via http://www.flu.org.cn/scn/article_detail.asp?articleId=24526)
Two clusters of influenza?like illness (ILI) occurred during the winter of 2024-2025 at a dog breeding facility in Shangqiu, Henan Province, China. Clinical samples were collected and tested for influenza ... Gary, E.N., Tursi, N.J., Hojecki, C.E. et al. Electroporation and LNP-mediated delivery of plasmid DNA-encoded H5N1 influenza virus hemagglutinin support protection against highly pathogenic avian influenza. npj Vaccines (2025). Abstract
submitted by kickingbird at Nov, 27, 2025 from npj Vaccines (2025) (via https://link.springer.com/article/10.1038/s41541-025-01316-5)
Highly pathogenic avian influenzas (HPAIs) is a continuing public health threat. Here, we describe the development of plasmid-encoded H5N1 hemagglutinin antigens representing clades that have caused human ... 9775 items, 20/Page, Page[14/489][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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