An Y, Ding X, Tian Y, Zhang M, Ma Y, Wu X, Cai M,. High-throughput pseudovirus neutralisation maps the antigenic landscape of influenza A/H1N1 viruses. EBioMedicine. 2025 Dec 2;122:106047. Abstract
submitted by kickingbird at 5 hours ago from EBioMedicine. 2025 Dec 2;122:106047 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: The continuous mutations in the haemagglutinin gene in A/H1N1 influenza viruses drives antigenic drift, necessitating frequent vaccine updates. Pseudovirus systems, with their flexible HA protein ... Huddleston J, Bedford T. Timely vaccine strain selection and genomic surveillance improve evolutionary forecast accuracy of seasonal influenza A/H3N2. Elife. 2025 Dec 4;14:RP104282. Abstract
submitted by kickingbird at 5 hours ago from Elife. 2025 Dec 4;14:RP104282 (via https://elifesciences.org/articles/104282)
Evolutionary forecasting models inform seasonal influenza vaccine design by predicting which current genetic variants will dominate in the influenza season 12 months later. Forecasting models depend on ... Frutos AM, Moon S, Binder AM, Cool AJ, Iyawe K, Th. Evaluation of a Novel Data Source for National Influenza Surveillance: Influenza Hospitalization Data in the National Healthcare Safety Network, United States, September 2021-April 2024. Am J Public Health. 2025 Dec 4:e1-e5. Abstract
submitted by kickingbird at 5 hours ago from Am J Public Health. 2025 Dec 4:e1-e5 (via https://ajph.aphapublications.org/doi/full/10.2105/AJPH.2025)
Objectives. To evaluate the completeness and utility of influenza hospital data reported to the Centers for Disease Control and Prevention's National Healthcare Safety Network (NHSN) from September 2021 ... ECDC. Scenarios for pre-pandemic zoonotic influenza preparedness and response. ECDC. Abstract
submitted by kickingbird at 5 hours ago from ECDC (via https://www.ecdc.europa.eu/en/publications-data/scenarios-pr)
We have defined 14 scenarios based on specific epidemiological and virological factors, including animal origin, characteristics of human cases (number and exposure context), severity signals, that are ... Guan L, etc., al. Stability of Avian Influenza A(H5N1) Virus in Milk from Infected Cows and Virus-Spiked Milk. N Engl J Med . 2025 Dec 4;393(22):2271-2273. Abstract
submitted by kickingbird at 1 days ago from N Engl J Med . 2025 Dec 4;393(22):2271-2273 (via https://www.nejm.org/doi/10.1056/NEJMc2502494)
In March 2024, public health agencies in the United States reported highly pathogenic avian influenza (HPAI) virus of subtype A(H5N1) in dairy cattle, with virus detected in milk samples from symptomatic ... Kerry Goldin, Meaghan Flagg, Tessa Lutterman, etc. Contemporary highly pathogenic avian influenza (H5N1) viruses retain neurotropism in human cerebral organoids. Open Forum Infectious Diseases, ofaf730. Abstract
submitted by kickingbird at 2 days ago from Open Forum Infectious Diseases, ofaf730 (via https://academic.oup.com/ofid/advance-article/doi/10.1093/of)
BackgroundClade 2.3.4.4b highly pathogenic avian influenza (HPAI) H5N1 viruses are widely circulating in North America with unprecedented transmission into novel host species. A high incidence of neurologic ... Jaume A. Badia-Boher, Michael Schaub, etc.,al. Evaluating the demographic impacts of the highly pathogenic avian influenza panzootic. Journal of Applied Ecology. Abstract
submitted by kickingbird at 2 days ago from Journal of Applied Ecology (via https://besjournals.onlinelibrary.wiley.com/doi/10.1111/1365)
The spread of a new highly pathogenic avian influenza virus (HPAIV-H5N1) has, since 2021, triggered one of the most severe wildlife panzootic ever reported, with suspected population crashes in hundreds ... Maddock KJ. 0. A raw deal: the intersection of the immunocompromised cat, influenza, and a lapse of infection prevention and control measures. ASM Case Rep 0:e00180-25. Abstract
submitted by kickingbird at 2 days ago from ASM Case Rep 0:e00180-25 (via https://journals.asm.org/doi/10.1128/asmcr.00180-25)
The case report by Chen et al. (ASM Case Rep 1:e00134-25, 2025, https://doi.org/10.1128/asmcr.00134-25) importantly describes nosocomial transmission of highly pathogenic avian influenza (HPAI) in an immunocompromised ... Zhang J, Cao R, Wang Y, Sun Y, Ji X, et al. Influenza virus infection reprograms cholesterol biosynthesis to facilitate virus replication by the TAK1-RORγ axis. PLOS Pathogens 21(10): e1013646. Abstract
submitted by kickingbird at 2 days ago from PLOS Pathogens 21(10): e1013646 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Infection and replication of enveloped viruses require host cells to supply substantial amounts of cellular cholesterol for processes such as binding, entry, trafficking, assembly, and budding. However, ... Junyi Wu, etc.,al. Emerging adaptation of BJ/94 lineage H9N2 viruses to waterfowl: insights into enhanced replication and immune activation in the host cells. Poultry Science. Abstract
submitted by kickingbird at 2 days ago from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
H9N2 influenza viruses have adapted to terrestrial avian hosts via prolonged circulation in domestic chicken populations across South and Southeast Asia. Recent surveys have documented an increased incidence ... Yu, T.C., Kikawa, C., Dadonaite, B. et al. Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza haemagglutinin. Nat Ecol Evol (2025). Abstract
submitted by kickingbird at 2 days ago from Nat Ecol Evol (2025) (via https://www.nature.com/articles/s41559-025-02895-1)
The evolution of human influenza virus haemagglutinin (HA) involves simultaneous selection to acquire antigenic mutations that escape population immunity while preserving protein function and stability. ... Asaad, H.M., Hassanin, O., Saif-Edin, M. et al. The impact of innate and humoral immune mechanisms on vaccine induced protection against avian influenza H9N2 in broilers. Sci Rep 15, 43016 (2025). Abstract
submitted by kickingbird at 2 days ago from Sci Rep 15, 43016 (2025) (via https://www.nature.com/articles/s41598-025-28122-2)
Avian influenza virus (AIV) (H9N2) is a highly contagious avian respiratory disease that causes significant economic losses in the poultry industry sector. Although immunological responses to AIV (H9N2) ... Hayes, S., Hilton, J., Mould-Quevedo, J. et al. Ecology and environment predict spatially stratified risk of H5 highly pathogenic avian influenza clade 2.3.4.4b in wild birds across Europe. Sci Rep (2025). Abstract
submitted by kickingbird at 2 days ago from Sci Rep (2025) (via https://www.nature.com/articles/s41598-025-30651-9)
Highly pathogenic avian influenza (HPAI) represents a threat to animal and human health, with the ongoing H5N1 outbreak within the H5 2.3.4.4b clade being one of the largest on record. However, it remains ... Filipe JAN, Wong CKH, van Leeuwen E, Goodfellow L,. A systematised review of seasonal influenza case-fatality risk. Vaccine. 2025 Nov 29;60 Suppl 2:128011. Abstract
submitted by kickingbird at 2 days ago from Vaccine. 2025 Nov 29;60 Suppl 2:128011 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Case-fatality risk (CFR) is an important indicator of disease severity for influenza infection and an input to estimates of influenza burden and vaccination impact. However, CRF estimates based on laboratory-confirmed ... Wang, P., Fu, J., Wu, H. et al. Isolation and characterization of a novel reassortant H3N8 avian influenza virus from chickens in Eastern China. Virus Genes. 2025 Dec 1. Abstract
submitted by kickingbird at 2 days ago from Virus Genes. 2025 Dec 1 (via https://link.springer.com/article/10.1007/s11262-025-02200-z)
The H3 avian influenza virus (AIV) is a common avian pathogen, widely prevalent among domestic poultry and wild birds. In China, H3N8 AIVs led to two confirmed cases of human infection in 2022, followed ... Wang, J., Chen, P., Liu, Q. et al. Adaptive mutations in HA of avian H9N2 influenza viruses facilitate their transmission to swine. Vet Res (2025). Abstract
submitted by kickingbird at 2 days ago from Vet Res (2025) (via https://link.springer.com/article/10.1186/s13567-025-01678-7)
The cross-species transmission of avian H9N2 influenza viruses to swine increases the risk of viral adaptation to mammalian hosts. However, the mechanisms by which these H9 viruses can overcome the barriers ... WPRO. Avian Influenza Weekly Update # 1024: 28 November 2025. WHO. Abstract
submitted by kickingbird at 4 days ago from WHO (via https://www.who.int/westernpacific/publications/m/item/avian)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ... Zhang W, Cowling BJ, Tam JSL, Abraham T, Chen H, D. Research Priorities for Zoonotic and Pandemic Influenza Vaccines: Evidence and Recommendations from the WHO Public Health Research Agenda for Influenza (2024 Update). Vaccines. 2025; 13(12):1206. Abstract
submitted by kickingbird at 4 days ago from Vaccines. 2025; 13(12):1206 (via https://www.mdpi.com/2076-393X/13/12/1206)
Zoonotic influenza viruses, including highly pathogenic avian influenza and swine-origin variants, continue to cause sporadic human infections with, in some cases, high case fatality rates and potential ... Li W, Shi Y, Li D, Wang Y, Sun Y, Li H, Han Y. A CRISPR Powered Immobilization-Free, Amplification-Free Carbon-Nanotube Field-Effect Transistor (FET) Sensor for Influenza A Virus (IAV). Molecules. 2025; 30(23):4608. Abstract
submitted by kickingbird at 4 days ago from Molecules. 2025; 30(23):4608 (via https://www.mdpi.com/1420-3049/30/23/4608)
The epidemic of infectious diseases, such as influenza A, has imposed a severe health burden on the population. Early detection, diagnosis, reporting, isolation, and treatment are crucial for the prevention, ... Zhao Z, Lan N, Chen Y, Yang J, Bai J, Liu J. Changing Epidemiology of Influenza Infections Among Children in the Post-Pandemic Period: A Case Study in Xi’an, China. Vaccines. 2025; 13(12):1214. Abstract
submitted by kickingbird at 4 days ago from Vaccines. 2025; 13(12):1214 (via https://www.mdpi.com/2076-393X/13/12/1214)
Background: The epidemiology of influenza was disrupted during the COVID-19 pandemic. Following the relaxation of non-pharmaceutical interventions, influenza viruses have re-emerged and caused epidemics ... 9542 items, 20/Page, Page[1/478][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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