YANG H, Chang JC, Guo Z, Carney PJ, et al. Structural stability of influenza A(H1N1)pdm09 virus hemagglutinins. J Virol. 2014 Feb 12.. Abstract
submitted by kickingbird at Feb, 16, 2014 from J Virol. 2014 Feb 12. (via http://www.ncbi.nlm.nih.gov/pubmed/24522930)
The non-covalent interactions that mediate trimerization of the influenza hemagglutinin (HA) are important determinants of its biological activities. Recent studies have demonstrated that mutations in ... HE L, Wu Q, Jiang K, Duan Z, et al. Differences in transmissibility and pathogenicity of reassortants between H9N2 and 2009 pandemic H1N1 influenza A viruses from humans and swine. Arch Virol. 2014 Feb 9. Abstract
submitted by kickingbird at Feb, 16, 2014 from Arch Virol. 2014 Feb 9 (via http://www.ncbi.nlm.nih.gov/pubmed/24510170)
Both H9N2 subtype avian influenza and 2009 pandemic H1N1 viruses (pH1N1) can infect humans and pigs, which provides the opportunity for virus reassortment, leading to the genesis of new strains with potential ... IVACHTCHENKO AV, Ivanenkov YA, Mitkin OD, Yamanush. A novel influenza virus neuraminidase inhibitor AV5027. Antiviral Res. 2013 Oct 24. pii: S0166-3542. Abstract
submitted by kickingbird at Feb, 16, 2014 from Antiviral Res. 2013 Oct 24. pii: S0166-3542 (via http://www.ncbi.nlm.nih.gov/pubmed/24513312)
A medium-sized focused library of novel Oseltamivir structural analogues with promising antiviral activity was successfully synthesized using a combinatorial approach. The synthesized compounds were then ... SH Wei, etc.,al. Human infection with avian influenza A H6N1 virus: an epidemiological analysis. The Lancet Respiratory Medicine, Volume 1, Issue. Abstract
submitted by kickingbird at Feb, 5, 2014 from The Lancet Respiratory Medicine, Volume 1, Issue (via http://www.thelancet.com/journals/lanres/article/PIIS2213-26)
Background
Avian influenza A H6N1 virus is one of the most common viruses isolated from wild and domestic avian species, but human infection with this virus has not been previously reported. We report ... Chen H, Yuan H, Gao R, et al. Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study. Lancet 2014 (published online Feb 4). Abstract
submitted by kickingbird at Feb, 5, 2014 from Lancet 2014 (published online Feb 4) (via http://www.thelancet.com/journals/lancet/article/PIIS0140-67)
Background
Human infections with different avian influenza viruses—eg, H5N1, H9N2, and H7N9—have raised concerns about pandemic potential worldwide. We report the first human infection with a novel ... WHO. Background and summary of human infection with influenza A(H7N9) virus. WHO. Abstract
submitted by kickingbird at Feb, 2, 2014 from WHO (via http://www.who.int/influenza/human_animal_interface/20140131)
in association with poultry outbreaks. The infections mainly resulted in conjunctivitis and mild upper respiratory symptoms, with the exception of one death, which occurred in the Netherlands.Since the ... Jones JC, Sonnberg S, Ko?er ZA, Shanmuganatham K,. Possible Role of Songbirds and Parakeets in Transmission of Influenza A(H7N9) Virus to Humans. Emerg Infect Dis. 2014 Mar. Abstract
submitted by kickingbird at Feb, 2, 2014 from Emerg Infect Dis. 2014 Mar (via http://wwwnc.cdc.gov/eid/article/20/3/13-1271_article.htm)
Avian-origin influenza A(H7N9) recently emerged in China, causing severe human disease. Several subtype H7N9 isolates contain influenza genes previously identified in viruses from finch-like birds. Because ... Verhagen JH, Majoor G, Lexmond P, Vuong O, Kasemir. Epidemiology of Influenza A Virus among Black-headed Gulls, the Netherlands, 2006–2010. Emerg Infect Dis. 2014 Jan. Abstract
submitted by kickingbird at Jan, 28, 2014 from Emerg Infect Dis. 2014 Jan (via http://wwwnc.cdc.gov/eid/article/20/1/13-0984_article.htm)
We sampled 7,511 black-headed gulls for influenza virus in the Netherlands during 2006–2010 and found that subtypes H13 and H16 caused annual epidemics in fledglings on colony sites. Our findings validate ... Guo L, Zhang X, Ren L, Yu X, Chen L, Zhou H, et al. Human Antibody Responses to Avian Influenza A(H7N9) Virus, 2013. 2013. Emerg Infect Dis. 2014 Feb. Abstract
submitted by kickingbird at Jan, 27, 2014 from 2013. Emerg Infect Dis. 2014 Feb (via http://wwwnc.cdc.gov/eid/article/20/2/13-1094_article.htm)
Understanding host antibody response is crucial for predicting disease severity and for vaccine development. We investigated antibody responses against influenza A(H7N9) virus in 48 serum samples from ... Komadina N, McVernon J, Hall R, Leder K.. A Historical Perspective of Influenza A(H1N2) Virus. Emerg Infect Dis. 2014 Jan. Abstract
submitted by kickingbird at Jan, 27, 2014 from Emerg Infect Dis. 2014 Jan (via http://wwwnc.cdc.gov/eid/article/20/1/12-1848_article.htm)
The emergence and transition to pandemic status of the influenza A(H1N1)A(H1N1)pdm09) virus in 2009 illustrated the potential for previously circulating human viruses to re-emerge in humans and cause a ... Westgeest KB, Russell CA, Lin X, Spronken MI, et a. Genome-wide Analysis of Reassortment and Evolution of Human Influenza A(H3N2) Viruses Circulating between 1968 and 2011. J Virol 2013.. Abstract
submitted by kickingbird at Jan, 4, 2014 from J Virol 2013. (via http://www.ncbi.nlm.nih.gov/m/pubmed/24371052/)
Influenza A(H3N2) viruses became widespread in humans during the 1968 H3N2 virus pandemic and have been a major cause of influenza epidemics ever since. The viruses evolve continuously by reassortment ... Yamayoshi S, Yamada S, Fukuyama S, Murakami S, et. Virulence-Affecting Amino Acid Changes in the PA Protein of H7N9 Influenza A Viruses. J Virol 2013. Abstract
submitted by kickingbird at Jan, 4, 2014 from J Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24371069/)
Novel avian-origin influenza A(H7N9) viruses were first reported to infect humans in March 2013. To date, 143 human cases, including 45 deaths, have been recorded. By using sequence comparisons and phylogenetic ... Bissel SJ, Wang G, Carter DM, Crevar CJ, et al.. H1N1, but not H3N2, influenza A virus infection protects ferrets from H5N1 encephalitis. J Virol 2013.. Abstract
submitted by kickingbird at Jan, 4, 2014 from J Virol 2013. (via http://www.ncbi.nlm.nih.gov/m/pubmed/24371072/)
Seasonal influenza causes substantial morbidity and mortality because of efficient human-to-human spread. Rarely, zoonotic strains of influenza virus spread to humans, where they have the potential to ... Binh NT, Wakai C, Kawaguchi A, Nagata K, et al. Involvement of the N-terminal portion of influenza virus RNA polymerase subunit PB1 in nucleotide recognition. Biochem Biophys Res Commun 2013 Dec 19. pii: S0006. Abstract
submitted by kickingbird at Jan, 4, 2014 from Biochem Biophys Res Commun 2013 Dec 19. pii: S0006 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24361882/)
The influenza virus PB1 protein functions as a catalytic subunit of the viral RNA-dependent RNA polymerase and contains the highly conserved motifs of RNA-dependent RNA polymerases together with putative ... Varich NL, Sadykova GK, Prilipov AG, Kochergin-Nik. Location and architecture of an antibody-binding site of influenza A virus nucleoprotein. Arch Virol 2013. Abstract
submitted by kickingbird at Jan, 4, 2014 from Arch Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24357080/)
Amino acid positions recognized by monoclonal antibodies (MAbs) in the influenza A virus nucleoprotein (NP) have been reported. As these residues were scattered in the three-dimensional (3D) structure ... KIM JC, Kim HM, Kang YM, Ku KB, et al.. Severe pathogenesis of influenza B virus in pregnant mice. Virology. 2014;448:74-81.. Abstract
submitted by kickingbird at Dec, 16, 2013 from Virology. 2014;448:74-81. (via http://www.ncbi.nlm.nih.gov/m/pubmed/24314638/)
The study on pathogenesis of influenza B virus during pregnancy is limited. Here, we showed using a mouse model that influenza B virus could cause severe disease including death during pregnancy. Infected ... KRAMMER F, Margine I, Hai R, Flood A, et al. H3 stalk-based chimeric hemagglutinin influenza virus constructs protect mice from H7N9 challenge. J Virol. 2013 Dec 4. Abstract
submitted by kickingbird at Dec, 16, 2013 from J Virol. 2013 Dec 4 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24307585/)
The recent outbreak of H7N9 influenza virus infections in humans in China has raised concerns about the pandemic potential of this strain. Here we test the efficacy of H3-stalk based chimeric hemagglutinin ... JOB ER, Bottazzi B, Short KR, Deng YM, et al.. A Single Amino Acid Substitution in the Hemagglutinin of H3N2 Subtype Influenza A Viruses Is Associated with Resistance to the Long Pentraxin PTX3 and Enhanced Virulence in Mice. J Immunol. 2013. Abstract
submitted by kickingbird at Dec, 16, 2013 from J Immunol. 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24307735/)
The long pentraxin, pentraxin 3 (PTX3), can play beneficial or detrimental roles during infection and disease by modulating various aspects of the immune system. There is growing evidence to suggest that ... JARU-AMPORNPAN P, Narkpuk J, Wanitchang A, Jongkae. Nucleoprotein of influenza B virus binds to its type A counterpart and disrupts influenza A viral polymerase complex formation. Biochem Biophys Res Commun. 2013 Dec 2. pii: S0006. Abstract
submitted by kickingbird at Dec, 16, 2013 from Biochem Biophys Res Commun. 2013 Dec 2. pii: S0006 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24309113/)
Upon co-infection with influenza B virus (FluB), influenza A virus (FluA) replication is substantially impaired. Previously, we have shown that the nucleoprotein of FluB (BNP) can inhibit FluA polymerase ... TARBET EB, Vollmer AH, Hurst BL, Barnard DL, et al. In vitro activity of favipiravir and neuraminidase inhibitor combinations against oseltamivir-sensitive and oseltamivir-resistant pandemic influenza A (H1N1) virus. Arch Virol. 2013. Abstract
submitted by kickingbird at Dec, 16, 2013 from Arch Virol. 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24311151/)
Few anti-influenza drugs are licensed in the United States for the prevention and therapy of influenza A and B virus infections. This shortage, coupled with continuously emerging drug resistance, as detected ... 7473 items, 20/Page, Page[260/374][|<<] [|<] [251] [252] [253] [254] [255] [256] [257] [258] [259] [260] [>|] [>>|] |
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