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2024-5-10 10:43:51
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Liu Y, Zeng Q, Hu X, Xu Z, Pan C, Liu Q, Yu J, Wu. Natural variant R246K in hemagglutinin increased zoonotic characteristics and renal inflammation in mice infected with H9N2 influenza virus. Vet Microbiol. 2023 Feb 3;279:109667.  Abstract  
submitted by kickingbird at Feb, 23, 2023 from Vet Microbiol. 2023 Feb 3;279:109667 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Considered a potential pandemic candidate, the widespread among poultry of H9N2 avian influenza viruses across Asia and North Africa pose an increasing threat to poultry and human health. The massive epidemic ...

Yin Y, Liu Y, Fen J, Liu K, Qin T, Chen S, Peng D,. Characterization of an H7N9 Influenza Virus Isolated from Camels in Inner Mongolia, China. Microbiol Spectr. 2023 Feb 21:e0179822.  Abstract  
submitted by kickingbird at Feb, 23, 2023 from Microbiol Spectr. 2023 Feb 21:e0179822 (via https://journals.asm.org/doi/10.1128/spectrum.01798-22)
The H7N9 subtype of influenza virus can infect birds and humans, causing great losses in the poultry industry and threatening public health worldwide. However, H7N9 infection in other mammals has not been ...

Wang T, Zhang J, Wang Y, Li Y, Wang L, Yu Y, Yao Y. Influenza-trained mucosal-resident alveolar macrophages confer long-term antitumor immunity in the lungs. Nat Immunol. 2023 Feb 20.  Abstract  
submitted by kickingbird at Feb, 23, 2023 from Nat Immunol. 2023 Feb 20 (via https://www.nature.com/articles/s41590-023-01428-x)
Respiratory viral infections reprogram pulmonary macrophages with altered anti-infectious functions. However, the potential function of virus-trained macrophages in antitumor immunity in the lung, a preferential ...

Nemoto M, Reedy SE, Yano T, Suzuki K, Fukuda S, Ga. Antigenic comparison of H3N8 equine influenza viruses belonging to Florida sublineage clade 1 between vaccine strains and North American strains isolated in 2021-2022. Arch Virol. 2023 Feb 19;168(3):94.  Abstract  
submitted by kickingbird at Feb, 23, 2023 from Arch Virol. 2023 Feb 19;168(3):94 (via https://pubmed.ncbi.nlm.nih.gov/36806782/)
Equine influenza virus strains of Florida sublineage clade 1 (Fc1) have been circulating in North America. In this study, virus neutralization assays were performed to evaluate antigenic differences between ...

Chien YA, Alford BK, Wasik BR, Weichert WS, Parris. Single Particle Analysis of H3N2 Influenza Entry Differentiates the Impact of the Sialic Acids (Neu5Ac and Neu5Gc) on Virus Binding and Membrane Fusion. J Virol. 2023 Feb 13:e0146322.  Abstract  
submitted by kickingbird at Feb, 17, 2023 from J Virol. 2023 Feb 13:e0146322 (via https://journals.asm.org/doi/10.1128/jvi.01463-22)
Entry of influenza A viruses (IAVs) into host cells is initiated by binding to sialic acids (Sias), their primary host cell receptor, followed by endocytosis and membrane fusion to release the viral genome ...

He D, Gu M, Wang X, Yan Y, Li Y, Wang X, Hu S, Liu. Reintroduction of highly pathogenic avian influenza A H7N9 virus in southwestern China. Virus Genes. 2023 Feb 13:1–5.  Abstract  
submitted by kickingbird at Feb, 17, 2023 from Virus Genes. 2023 Feb 13:1–5 (via https://link.springer.com/article/10.1007/s11262-023-01974-4)
Highly pathogenic (HP) avian influenza A H7N9 virus has emerged in China since 2016. In recent years, it has been most prevalent in northern China. However, several strains of HP H7N9 reappeared in southwestern ...

Wang S, Zhuang Q, Jiang N, Zhang F, Chen Q, Zhao R. Reverse transcription recombinase-aided amplification assay for avian influenza virus. Virus Genes. 2023 Feb 13.  Abstract  
submitted by kickingbird at Feb, 17, 2023 from Virus Genes. 2023 Feb 13 (via https://link.springer.com/article/10.1007/s11262-023-01979-z)
Avian influenza virus (AIV) infection can lead to severe economic losses in the poultry industry and causes a serious risk for humans. A rapid and simple test for suspected viral infection cases is crucial. ...

Günl F, Krischuns T, Schreiber JA, Henschel L, Wah. The ubiquitination landscape of the influenza A virus polymerase. Nat Commun. 2023 Feb 11;14(1):787.  Abstract  
submitted by kickingbird at Feb, 13, 2023 from Nat Commun. 2023 Feb 11;14(1):787 (via https://www.nature.com/articles/s41467-023-36389-0)
During influenza A virus (IAV) infections, viral proteins are targeted by cellular E3 ligases for modification with ubiquitin. Here, we decipher and functionally explore the ubiquitination landscape of ...

Chen C, Jiang D, Yan D, Pi L, Zhang X, Du Y, Liu X. The global region-specific epidemiologic characteristics of influenza: WHO FluNet data from 1996 to 2021. Int J Infect Dis. 2023 Feb 9:S1201-9712(23)00052-8.  Abstract  
submitted by kickingbird at Feb, 13, 2023 from Int J Infect Dis. 2023 Feb 9:S1201-9712(23)00052-8 (via https://www.ijidonline.com/article/S1201-9712(23)00052-8/ful)
Background: This study aimed to investigate region-specific epidemiologic characteristics of influenza and influenza transmission zones (ITZs).Methods: Weekly influenza surveillance data of 156 countries ...

Heinemann AS, Stalp JL, Bonifacio JPP, Silva F, Wi. Silent neonatal influenza A virus infection primes systemic antimicrobial immunity. Front Immunol. 2023 Jan 24;14:1072142.  Abstract  
submitted by kickingbird at Feb, 11, 2023 from Front Immunol. 2023 Jan 24;14:1072142 (via https://www.frontiersin.org/articles/10.3389/fimmu.2023.1072)
Infections with influenza A viruses (IAV) cause seasonal epidemics and global pandemics. The majority of these infections remain asymptomatic, especially among children below five years of age. Importantly, ...

Li K, McCaw JM, Cao P. Enhanced viral infectivity and reduced interferon production are associated with high pathogenicity for influenza viruses. PLoS Comput Biol. 2023 Feb 9;19(2):e1010886.  Abstract  
submitted by kickingbird at Feb, 10, 2023 from PLoS Comput Biol. 2023 Feb 9;19(2):e1010886 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Epidemiological and clinical evidence indicates that humans infected with the 1918 pandemic H1N1 influenza virus and highly pathogenic avian H5N1 influenza viruses often displayed severe lung pathology. ...

Sims A, Tornaletti LB, Jasim S, Pirillo C, Devlin. Superinfection exclusion creates spatially distinct influenza virus populations. PLoS Biol. 2023 Feb 9;21(2):e3001941.  Abstract  
submitted by kickingbird at Feb, 10, 2023 from PLoS Biol. 2023 Feb 9;21(2):e3001941 (via https://journals.plos.org/plosbiology/article?id=10.1371/jou)
Interactions between viruses during coinfections can influence viral fitness and population diversity, as seen in the generation of reassortant pandemic influenza A virus (IAV) strains. However, opportunities ...

Kayed AE, Kutkat O, Kandeil A, Moatasim Y, El Tawe. Comparative pathogenic potential of avian influenza H7N3 viruses isolated from wild birds in Egypt and their sensitivity to commercial antiviral drugs. Arch Virol. 2023 Feb 9;168(3):82.  Abstract  
submitted by kickingbird at Feb, 10, 2023 from Arch Virol. 2023 Feb 9;168(3):82 (via https://link.springer.com/article/10.1007/s00705-022-05646-w)
Active surveillance and studying the virological features of avian-origin influenza viruses are essential for early warning and preparedness for the next potential pandemic. During our active surveillance ...

Vangeti S, Falck-Jones S, Yu M, ?sterberg B, Liu S. Human influenza virus infection elicits distinct patterns of monocyte and dendritic cell mobilization in blood and the nasopharynx. Elife. 2023 Feb 8;12:e77345.  Abstract  
submitted by kickingbird at Feb, 10, 2023 from Elife. 2023 Feb 8;12:e77345 (via https://elifesciences.org/articles/77345)
During respiratory viral infections, the precise roles of monocytes and dendritic cells (DCs) in the nasopharynx in limiting infection and influencing disease severity are incompletely described. We studied ...

Wan Z, Zhao Z, Sang J, Jiang W, Chen J, Tang T, Li. Amino Acid Variation at Hemagglutinin Position 193 Impacts the Properties of H9N2 Avian Influenza Virus. J Virol. 2023 Feb 7:e0137922.  Abstract  
submitted by kickingbird at Feb, 8, 2023 from J Virol. 2023 Feb 7:e0137922 (via https://journals.asm.org/doi/10.1128/jvi.01379-22)
Despite active control strategies, including the vaccination program in poultry, H9N2 avian influenza viruses possessing mutations in hemagglutinin (HA) were frequently isolated. In this study, we analyzed ...

Scheibner D, Salaheldin AH, Bagato O, Zaeck LM, Mo. Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses. PLoS Pathog. 2023 Feb 6;19(2):e1011135.  Abstract  
submitted by kickingbird at Feb, 8, 2023 from PLoS Pathog. 2023 Feb 6;19(2):e1011135 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic, potentially pre-pandemic, transmission to humans. ...

Sun H, Deng G, Sun H, Song J, Zhang W, Li H, Wei X. N-linked glycosylation enhances hemagglutinin stability in avian H5N6 influenza virus to promote adaptation in mammals. PNAS Nexus. 2022 Jun 8;1(3):pgac085.  Abstract  
submitted by kickingbird at Feb, 7, 2023 from PNAS Nexus. 2022 Jun 8;1(3):pgac085 (via https://academic.oup.com/pnasnexus/article/1/3/pgac085/66043)
Clade 2.3.4.4 avian H5Ny viruses, namely H5N2, H5N6, and H5N8, have exhibited unprecedented intercontinental spread in poultry. Among them, only H5N6 viruses are frequently reported to infect mammals and ...

Scheibner D, Salaheldin AH, Bagato O, Zaeck LM, Mo. Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses. PLoS Pathog. 2023 Feb 6;19(2):e1011135.  Abstract  
submitted by kickingbird at Feb, 7, 2023 from PLoS Pathog. 2023 Feb 6;19(2):e1011135 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic, potentially pre-pandemic, transmission to humans. ...

Xie R, Wang W, Gao Y, Liu W, Yue B, Liu S, Fan W,. Evolution and mammalian adaptation of H3 and H10 subtype avian influenza viruses in wild birds in Yancheng Wetland of China. Vet Microbiol. 2023 Jan 23;279:109669..  Abstract  
submitted by kickingbird at Feb, 4, 2023 from Vet Microbiol. 2023 Jan 23;279:109669. (via https://www.sciencedirect.com/science/article/pii/S037811352)
Wild birds play a critical role in avian influenza virus (AIV) ecology and some outbreaks of avian influenza in human originate from wild birds, suggesting that epidemiological surveillance and interspecies-transmission ...

Yin X, Wu T, Peng C, Li J, Liu S, Hou G, Jiang W,. Genome sequence analysis of H7N3 subtype avian influenza virus originated from wild birds and its potential infectivity in mice. Virus Genes. 2023 Feb 3.  Abstract  
submitted by kickingbird at Feb, 4, 2023 from Virus Genes. 2023 Feb 3 (via https://link.springer.com/article/10.1007/s11262-023-01968-2)
In 2021, an H7N3 avian influenza virus (AIV) was isolated from a mallard in Tianhewan Yellow River National Wetland Park, Ningxia Hui Autonomous Region, China. Sequences analysis showed that this strain ...

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