Sheppard CM, Goldhill DH, Swann OC, Staller E, Pen. An Influenza A virus can evolve to use human ANP32E through altering polymerase dimerization. Nat Commun. 2023 Oct 10;14(1):6135. Abstract
submitted by kickingbird at Oct, 12, 2023 from Nat Commun. 2023 Oct 10;14(1):6135 (via https://www.nature.com/articles/s41467-023-41308-4)
Human ANP32A and ANP32B are essential but redundant host factors for influenza virus genome replication. While most influenza viruses cannot replicate in edited human cells lacking both ANP32A and ANP32B, ... Idoko-Akoh A, Goldhill DH, Sheppard CM, Bialy D, Q. Creating resistance to avian influenza infection through genome editing of the ANP32 gene family. Nat Commun. 2023 Oct 10;14(1):6136. Abstract
submitted by kickingbird at Oct, 12, 2023 from Nat Commun. 2023 Oct 10;14(1):6136 (via https://www.nature.com/articles/s41467-023-41476-3)
Chickens genetically resistant to avian influenza could prevent future outbreaks. In chickens, influenza A virus (IAV) relies on host protein ANP32A. Here we use CRISPR/Cas9 to generate homozygous gene ... Carnaccini S, Cáceres CJ, Gay LC, Ferreri LM, Skep. Antigenic mapping of the hemagglutinin of the H9 subtype influenza A viruses using sera from Japanese quail ( Coturnix c. japonica). J Virol. 2023 Oct 6:e0074323. Abstract
submitted by kickingbird at Oct, 7, 2023 from J Virol. 2023 Oct 6:e0074323 (via https://journals.asm.org/doi/10.1128/jvi.00743-23)
Influenza A viruses (FLUAV) of the H9N2 subtype are zoonotic pathogens that cause significant economic damage to the poultry industry. Vaccination to prevent and control H9N2 infections in poultry is widely ... McMahon M, Tan J, O´Dell G, Kirkpatrick Roub. Immunity induced by vaccination with recombinant influenza B virus neuraminidase protein breaks viral transmission chains in guinea pigs in an exposure intensity-dependent manner. J Virol. 2023 Oct 6:e0105723. Abstract
submitted by kickingbird at Oct, 7, 2023 from J Virol. 2023 Oct 6:e0105723 (via https://journals.asm.org/doi/10.1128/jvi.01057-23)
Mucosal vaccines and vaccines that block pathogen transmission are under-appreciated in vaccine development. However, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has shown ... Lebarbenchon C, Boucher S, Feare C, Dietrich M, La. Migratory patterns of two major influenza virus host species on tropical islands. R Soc Open Sci. 2023 Oct 4;10(10):230600. Abstract
submitted by kickingbird at Oct, 7, 2023 from R Soc Open Sci. 2023 Oct 4;10(10):230600 (via https://royalsocietypublishing.org/doi/10.1098/rsos.230600)
Animal migration is a major driver of infectious agent dispersal. Duck and seabird migrations, for instance, play a key role in the spatial transmission dynamics and gene flow of avian influenza viruses ... Kikuchi C, Antonopoulos A, Wang S, Maemura T, Kara. Glyco-engineered MDCK cells display preferred receptors of H3N2 influenza absent in eggs used for vaccines. Nat Commun. 2023 Oct 4;14(1):6178. Abstract
submitted by kickingbird at Oct, 5, 2023 from Nat Commun. 2023 Oct 4;14(1):6178 (via https://www.nature.com/articles/s41467-023-41908-0)
Evolution of human H3N2 influenza viruses driven by immune selection has narrowed the receptor specificity of the hemagglutinin (HA) to a restricted subset of human-type (Neu5Acα2-6 Gal) glycan receptors ... Sumner KM, Masalovich S, O´Halloran A, Holst. Severity of influenza-associated hospitalisations by influenza virus type and subtype in the USA, 2010-19: a repeated cross-sectional study. Lancet Microbe. 2023 Sep 25:S2666-5247(23)00187-8. Abstract
submitted by kickingbird at Oct, 1, 2023 from Lancet Microbe. 2023 Sep 25:S2666-5247(23)00187-8 (via https://www.thelancet.com/journals/lanmic/article/PIIS2666-5)
Background: Influenza burden varies across seasons, partly due to differences in circulating influenza virus types or subtypes. Using data from the US population-based surveillance system, Influenza Hospitalization ... Andreev K, Jones JC, Seiler P, Kandeil A, Turner J. Antiviral Susceptibility of Highly Pathogenic Avian Influenza A(H5N1) Viruses Circulating Globally in 2022-2023. J Infect Dis. 2023 Sep 28:jiad418. Abstract
submitted by kickingbird at Oct, 1, 2023 from J Infect Dis. 2023 Sep 28:jiad418 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
The antiviral susceptibility of currently circulating (2022-2023) highly pathogenic avian influenza (HPAI) A(H5N1) viruses was assessed by genotypic and phenotypic approaches. The frequency of neuraminidase ... Barkhasbaatar A, Gilbert M, Fine AE, Shiilegdamba. Ecological characterization of 175 low-pathogenicity avian influenza viruses isolated from wild birds in Mongolia, 2009-2013 and 2016-2018. Vet Med Sci. 2023 Sep 28. Abstract
submitted by kickingbird at Oct, 1, 2023 from Vet Med Sci. 2023 Sep 28 (via https://onlinelibrary.wiley.com/doi/10.1002/vms3.1281)
Background: Since 2005, highly pathogenic avian influenza A H5N1 viruses have spread from Asia worldwide, infecting poultry, humans and wild birds. Subsequently, global interest in avian influenza (AI) ... Lei Y, Sun Y, Wu W, Liu H, Wang X, Shu Y, Fang S. Influenza H7N9 virus disrupts the monolayer human brain microvascular endothelial cells barrier in vitro. Virol J. 2023 Sep 29;20(1):219. Abstract
submitted by kickingbird at Oct, 1, 2023 from Virol J. 2023 Sep 29;20(1):219 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Influenza H7N9 virus causes human infections with about 40% case fatality rate. The severe cases usually present with pneumonia; however, some present with central nervous system complications. Pneumonia ... Wang S, Zhang TH, Hu M, Tang K, Sheng L, Hong M, C. Deep mutational scanning of influenza A virus neuraminidase facilitates the identification of drug resistance mutations in vivo. mSystems. 2023 Sep 29:e0067023. Abstract
submitted by kickingbird at Oct, 1, 2023 from mSystems. 2023 Sep 29:e0067023 (via https://journals.asm.org/doi/10.1128/msystems.00670-23)
Neuraminidase (NA) is a pivotal surface enzyme and a key therapeutic target in combating the influenza A virus. Its evolution can lead to potential zoonotic transmission, seasonal epidemics, and the emergence ... Petrich A, Chiantia S. Influenza A Virus Infection Alters Lipid Packing and Surface Electrostatic Potential of the Host Plasma Membrane. Viruses. 2023 Aug 29;15(9):1830. Abstract
submitted by kickingbird at Sep, 29, 2023 from Viruses. 2023 Aug 29;15(9):1830 (via https://www.mdpi.com/1999-4915/15/9/1830)
The pathogenesis of influenza A viruses (IAVs) is influenced by several factors, including IAV strain origin and reassortment, tissue tropism and host type. While such factors were mostly investigated ... Kanekiyo M, Gillespie RA, Midgett M, O´Malle. Refined semi-lethal aerosol H5N1 influenza model in cynomolgus macaques for evaluation of medical countermeasures. iScience. 2023 Sep 6;26(10):107830. Abstract
submitted by kickingbird at Sep, 29, 2023 from iScience. 2023 Sep 6;26(10):107830 (via https://www.cell.com/iscience/fulltext/S2589-0042(23)01907-7)
Highly pathogenic avian influenza A H5N1 viruses cause high mortality in humans and have pandemic potential. Effective vaccines and treatments against this threat are urgently needed. Here, we have refined ... Seekings AH, Warren CJ, Thomas SS, Lean FZX, Selde. Different Outcomes of Chicken Infection with UK-Origin H5N1-2020 and H5N8-2020 High-Pathogenicity Avian Influenza Viruses (Clade 2.3.4.4b). Viruses. 2023 Sep 12;15(9):1909. Abstract
submitted by kickingbird at Sep, 29, 2023 from Viruses. 2023 Sep 12;15(9):1909 (via https://www.mdpi.com/1999-4915/15/9/1909)
Clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses (HPAIVs) of the "goose/Guangdong" lineage have caused a series of European epizootics since 2014. During autumn/winter 2020-2021, several H5Nx ... Takashita E, Fujisaki S, Morita H, Nagata S, Miura. A community cluster of influenza A(H3N2) virus infection with reduced susceptibility to baloxavir due to a PA E199G substitution in Japan, February to March 2023. Euro Surveill. 2023 Sep;28(39). Abstract
submitted by kickingbird at Sep, 29, 2023 from Euro Surveill. 2023 Sep;28(39) (via https://pubmed.ncbi.nlm.nih.gov/37768560/)
A community cluster of influenza A(H3N2) caused by viruses with an E199G substitution in PA was detected in Nara, Japan, between February and March 2023. The three patients with these mutant viruses had ... Pepin KM, Leach CB, Barrett NL, Ellis JW, VanDalen. Environmental transmission of influenza A virus in mallards. mBio. 2023 Sep 28:e0086223. Abstract
submitted by kickingbird at Sep, 29, 2023 from mBio. 2023 Sep 28:e0086223 (via https://journals.asm.org/doi/10.1128/mbio.00862-23)
Influenza A viruses present a major challenge for animal and human health. They circulate widely in wild waterfowl and frequently spillover into poultry, emphasizing the need for risk-based surveillance ... Soda K, Mekata H, Usui T, Ito H, Matsui Y, Yamada. Genetic and antigenic analyses of H5N8 and H5N1 subtypes high pathogenicity avian influenza viruses isolated from wild birds and poultry farms in Japan in the winter of 2021-2022. J Vet Med Sci. 2023 Sep 26. Abstract
submitted by kickingbird at Sep, 29, 2023 from J Vet Med Sci. 2023 Sep 26 (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_23)
In the winter of 2021-2022, multiple subtypes (H5N8 and H5N1) of high pathogenicity avian influenza viruses (HPAIVs) were confirmed to be circulating simultaneously in Japan. Here, we phylogenetically ... Qian Zhang, etc.,al. Isolation, identification and phylogenetic analysis of a wild bird-derived H1N1 avian influenza virus in the northern Tianshan Mountain. DOI： 10.3760/cma.j.cn112309-20200213-00060. Abstract
submitted by kickingbird at Sep, 23, 2023 from DOI： 10.3760/cma.j.cn112309-20200213-00060 (via https://rs.yiigle.com/cmaid/1257546)
ObjectiveTo analyze the complete genome sequence and phylogenetic structure of a wild bird-derived H1N1 avian influenza virus (AIV) in the northern Tianshan Mountain.MethodsIn November 2018, 320 samples ... Nana Chang, etc.,al. Isolation, identification and phylogenetic analysis of six strains of H5N6 highly pathogenic avian influenza virus. DOI： 10.3760/cma.j.cn112309-20210124-00036. Abstract
submitted by kickingbird at Sep, 23, 2023 from DOI： 10.3760/cma.j.cn112309-20210124-00036 (via https://rs.yiigle.com/cmaid/1317811)
ObjectiveTo analyze phylogenetic structure and molecular characteristics of H5N6 avian influenza virus (AIVs) isolated from live poultry market (LPM).MethodsOropharyngeal and cloacal swabs from poultry, ... Yonghu Wan, etc.,al. Genetic characteristics analysis of hemagglutinin gene of H9N2 subtype avian influenza viruses in Guizhou province. DOI： 10.3760/cma.j.cn112309-20201103-00498. Abstract
submitted by kickingbird at Sep, 20, 2023 from DOI： 10.3760/cma.j.cn112309-20201103-00498 (via https://rs.yiigle.com/cmaid/1317812)
ObjectiveTo understand the genetic variation and the prevalence of H9N2 subtype avian influenza virus in Guizhou province, and to provide the scientific evidence for the prevention and control of avian ... 5135 items, 20/Page, Page[13/257][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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