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2026-3-5 6:25:41
Article

Aljowaie RM, Aziz IM, Farrag MA, Almuqrin AM, Alma. Molecular Surveillance, Evolution, and Vaccine Strain Match of the HA and NA Genes of 2009 H1N1 Pandemic Virus Circulating in Riyadh, Saudi Arabia. Int J Mol Sci. 2026 Jan 30;27(3):1412.  Abstract  
submitted by kickingbird at Feb, 13, 2026 from Int J Mol Sci. 2026 Jan 30;27(3):1412 (via https://www.mdpi.com/1422-0067/27/3/1412)
Influenza viruses are characterized by their high mutation rates which require continuous molecular surveillance to ensure the annual effectiveness of influenza vaccines. The current study aimed to investigate ...

Papkiauri A, Urushadze L, Tevdoradze T, Sidamonidz. Genomic-based biosurveillance for avian influenza: whole genome sequencing from wild mallards sampled during autumn migration in 2022-2023 reveals a high co-infection rate on migration stopover site i. Front Microbiol. 2026 Jan 28;17:1735728.  Abstract  
submitted by kickingbird at Feb, 13, 2026 from Front Microbiol. 2026 Jan 28;17:1735728 (via https://www.frontiersin.org/journals/microbiology/articles/1)
The Caucasus region, including Georgia, is an important intersection for migratory waterbirds, offering potential for avian influenza virus (AIV) transmission between populations from different geographic ...

Guiomar R, Henriques C, Pereira da Silva S, Gomes. Cross-sectional study on protective antibodies against influenza A virus subtypes and cross-protection against influenza A(H3N2) subclade K, Portugal, August 2025. Euro Surveill. 2026 Feb;31(6).  Abstract  
submitted by kickingbird at Feb, 13, 2026 from Euro Surveill. 2026 Feb;31(6) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
The 2025/26 season was marked by co-circulation of influenza A subtypes, with the first detection of A(H3N2) subclade K in September 2025. In August 2025 in Portugal, 14.8% (95% CI: 12.2-17.8) of 886 persons ...

Ikonen N, Haveri A, Lindh E, Liedes O, Vara S, Pak. Reduced neutralising antibody responses against emerging 2025/26 influenza A(H1N1)pdm09 subclade D.3.1 and A(H3N2) subclade K viruses among healthcare workers, Finland, August to October 2025. Euro Surveill. 2026 Feb;31(6).  Abstract  
submitted by kickingbird at Feb, 13, 2026 from Euro Surveill. 2026 Feb;31(6) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
During autumn 2025, drifted influenza A(H3N2) subclade K and A(H1N1)pdm09 subclade D.3.1. and D.3.1.1 viruses were detected in Finland. We assessed antibody responses against 2024/25 vaccine and 2025/26 ...

Leyson CM, Vargas-Maldonado N, Gaddy M, Raghunatha. Viral lineage and mode of exposure modulate within-host spatial dynamics of influenza A viruses in a guinea pig model. J Virol. 2026 Feb 12:e0188925.  Abstract  
submitted by kickingbird at Feb, 13, 2026 from J Virol. 2026 Feb 12:e0188925 (via https://journals.asm.org/doi/10.1128/jvi.01889-25)
The upper and lower respiratory tracts (URT and LRT) present distinct environments for influenza A virus (IAV) replication. Their differential features have major implications for viral evolutionary dynamics, ...

Sanders CG, Liu M, Fusco JA, Ohl EM, Tarbuck NN, K. [preprint]Efficient replication of influenza D virus in the human airway underscores zoonotic potential. https://doi.org/10.64898/2026.02.07.704474.  Abstract  
submitted by kickingbird at Feb, 13, 2026 from https://doi.org/10.64898/2026.02.07.704474 (via https://www.biorxiv.org/content/10.64898/2026.02.07.704474v1)
Influenza D virus (IDV), primarily found in livestock species, has demonstrated cross-species transmission potential, yet its threat to humans remains poorly understood. Here, we curated a panel of IDV ...

Gagandeep Singh, etc.,al. [preprint]Population immunity to clade 2.3.4.4b H5N1 is dominated by anti-neuraminidase antibodies. https://doi.org/10.64898/2026.02.10.26346014.  Abstract  
submitted by kickingbird at Feb, 13, 2026 from https://doi.org/10.64898/2026.02.10.26346014 (via https://www.medrxiv.org/content/10.64898/2026.02.10.26346014)
Clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses continue to expand geographically and across mammalian hosts, raising concern about pandemic potential. The degree and specificity of pre-existing ...

Jiao J, Ding J, Sun Z, Chi C, Liu S, Jiang S, Chen. Characterization of a reassortant H3N2 swine influenza virus with 2009 pandemic internal genes and enhanced potential for zoonotic risk. Vet Microbiol. 2026 Feb 7;315:110937.  Abstract  
submitted by kickingbird at Feb, 13, 2026 from Vet Microbiol. 2026 Feb 7;315:110937 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Pigs serve as key "mixing vessels" for influenza A viruses, playing a critical role in cross-species transmission, while the H3N2 subtype represents an important lineage within the swine influenza virus ...

KE Qian, ZHENG Ju, WU Ping, ZHUANG Li. Analysis of the gene sequences of two cases of human infection with avian influenza H9N2 in Guizhou province in 2024. J Trop Med, Jan. 2026, Vol.26, No.1.  Abstract  
submitted by kickingbird at Feb, 12, 2026 from J Trop Med, Jan. 2026, Vol.26, No.1
Objective To explore the molecular characteristics of human infections with H9N2 avian influenza virus (AIV) in Guizhou province, so as to provide evidence for the prevention and control of avian influenza ...

Downey J, Oliveira-Coelho A, Kiss MG, Laghlali G,. Influenza hijacks myeloid cells to inflict type-I interferon-fueled damage in the heart. Immunity. 2026 Feb 9:S1074-7613(25)00567-9.  Abstract  
submitted by kickingbird at Feb, 12, 2026 from Immunity. 2026 Feb 9:S1074-7613(25)00567-9 (via https://www.cell.com/immunity/abstract/S1074-7613(25)00567-9)
Abundant evidence has correlated influenza infection with cardiovascular disease, yet mechanisms linking infection with the heart remain poorly understood. Here, we show that influenza infection damaged ...

Cardenas M, Compton S, Caceres CJ, García-Sastre A. MHC class II functions as a host-specific entry receptor for representative human and swine H3N2 influenza A viruses. Nat Commun. 2026 Feb 10.  Abstract  
submitted by kickingbird at Feb, 12, 2026 from Nat Commun. 2026 Feb 10 (via https://www.nature.com/articles/s41467-026-69267-6)
Influenza A viruses (FLUAV) utilize sialic acid to enter host cells via the envelope's hemagglutinin (HA), and its affinity for host-specific sialic acid linkage configuration is a major host range determinant. ...

Encinas P, Nogales A, Escribano-Romero E, Del Burg. Longitudinal Surveillance of Influenza A Virus Exposure in Wild Boars (Sus scrofa) in Spain (2015-2023): Serologic and Virologic Evidence of Subtype Infections and H5N1 Spillover Risk. Zoonoses Public Health. 2026 Feb 10.  Abstract  
submitted by kickingbird at Feb, 12, 2026 from Zoonoses Public Health. 2026 Feb 10 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.70040)
Introduction: Influenza A viruses (IAVs) are responsible for respiratory infections in a wide range of species, including birds, swine and humans. The role of wild boar (Sus scrofa) in IAV epidemiology ...

Bjorn Koel, etc.,al. [preprint]Emergence and antigenic characterisation of influenza A(H3N2) viruses with hemagglutinin substitutions N158K and K189R during the 2024/25 influenza season. https://doi.org/10.64898/2026.02.10.704996.  Abstract  
submitted by kickingbird at Feb, 11, 2026 from https://doi.org/10.64898/2026.02.10.704996 (via https://www.biorxiv.org/content/10.64898/2026.02.10.704996v1)
Background Seasonal human influenza viruses can escape from antibody-mediated neutralization when amino acid changes occur in the hemagglutinin protein. Routine surveillance identified circulation of an ...

Daiki Mori, Nicolas Sax, Nozomi Shimada, Mana Kuwa. Epitope specificity shapes the CD4+ T cell response to influenza virus infection in mice. International Immunology, 2026;, dxag008.  Abstract  
submitted by kickingbird at Feb, 11, 2026 from International Immunology, 2026;, dxag008 (via https://academic.oup.com/intimm/advance-article-abstract/doi)
Helper CD4+ T cells play a central role in orchestrating protective immune responses during infection and vaccination. Activation of na?ve CD4+ T cells is initiated by the recognition of antigenic peptides ...

Lejeune M, Tornos J, Bralet T, De Pasquale C, Mar?. Vaccination against H5 HP avian influenza virus leads to persistent immune response in wild king penguins. Nat Commun. 2026 Feb 9;17(1):1395.  Abstract  
submitted by kickingbird at Feb, 10, 2026 from Nat Commun. 2026 Feb 9;17(1):1395 (via https://www.nature.com/articles/s41467-026-69094-9)
Since 2021, the panzootic nature of high pathogenicity avian influenza (HPAI) represents an increasing threat to wild vertebrate populations. In this context, recent vaccines developed for poultry could ...

Ichikawa Y, Saito R, Chon I, Phyu WW, Kyaw Y, Win. Molecular Epidemiology and Genetic Diversity of Influenza B Viruses Based on Whole-Genome Analysis in Japan and Myanmar, 2016-2020. Influenza Other Respir Viruses. 2026 Feb;20(2):e70.  Abstract  
submitted by kickingbird at Feb, 10, 2026 from Influenza Other Respir Viruses. 2026 Feb;20(2):e70 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70234)
Background: Influenza B virus (IBV) contributes to seasonal epidemics, but its molecular evolution is less defined than influenza A. We analyzed IBVs collected in Japan and Myanmar (2016-2020) to investigate ...

Fang, K., Li, J., Zhao, H. et al. Assessing HPAI-H5 transmission risk across wild bird migratory flyways in the United States. Nat Commun (2026).  Abstract  
submitted by kickingbird at Feb, 10, 2026 from Nat Commun (2026) (via https://www.nature.com/articles/s41467-026-69344-w)
As natural hosts of avian influenza viruses, wild birds pose an increasing threat to public health. Here, using surveillance data from wild bird infections across the United States (2022-2025), we show ...

Li J, Wang D, Li B, Ma J, He X, Chen L, Kong H, De. Syrian hamster is an ideal animal model for evaluating the transmissibility of emerging influenza viruses. Emerg Microbes Infect. 2026 Feb 9:2629629.  Abstract  
submitted by kickingbird at Feb, 10, 2026 from Emerg Microbes Infect. 2026 Feb 9:2629629 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Multiple influenza virus subtypes actively circulate in nature, and assessing their transmissibility provides crucial information for predicting their pandemic potential and for pandemic preparedness. ...

Li Y, Zhu C, Wang Y, Miller H, Benlagha K, Byazrov. The role of T cells in influenza infection and vaccination. Virol Sin. 2026 Feb 5:S1995-820X(26)00017-9.  Abstract  
submitted by kickingbird at Feb, 9, 2026 from Virol Sin. 2026 Feb 5:S1995-820X(26)00017-9 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Influenza virus infections cause significant illness or death every year, becoming a serious health risk. Currently, influenza vaccines mainly induce responses to antibodies against specific strains, but ...

Lingling Wang, etc.,al. Pre-Amplified dsDNA-Tag Lateral Flow Assay for Highly Sensitive Point-of-Care Detection of Influenza A H1N1. Biochimie.  Abstract  
submitted by kickingbird at Feb, 9, 2026 from Biochimie (via https://www.sciencedirect.com/science/article/abs/pii/S03009)
The current immediate detection of influenza A (H1N1) virus faces the dual challenges of insufficient sensitivity and the risk of amplification contamination. Here, we developed a novel lateral flow nucleic ...

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