El Sahly HM, Atmar RL. An Early Look at mRNA Vaccines to Prevent Influenza. N Engl J Med. 2025 Nov 20;393(20):2048-2050. Abstract
submitted by kickingbird at 14 days ago from N Engl J Med. 2025 Nov 20;393(20):2048-2050 (via https://www.nejm.org/doi/full/10.1056/NEJMe2514597)
Annual influenza vaccination campaigns are a trusted tool in efforts to decrease the morbidity and mortality of influenza in the United States, with an effectiveness of 36 to 54% at preventing influenza-related ... Fitz-Patrick D, McVinnie DS, Jackson LA, Crowther. Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine. N Engl J Med. 2025 Nov 20;393(20):2001-2011. Abstract
submitted by kickingbird at 14 days ago from N Engl J Med. 2025 Nov 20;393(20):2001-2011 (via https://www.nejm.org/doi/10.1056/NEJMoa2416779)
Background: Influenza remains a major health burden despite the use of licensed vaccines. Nucleoside-modified messenger RNA (modRNA) influenza vaccines have shown promising immunogenicity against influenza ... European Centre for Disease Prevention and Control. Threat Assessment Brief: Assessing the risk of influenza for the EU/EEA in the context of increasing circulation of A(H3N2) subclade K. European Centre for Disease Prevention and Control. Abstract
submitted by kickingbird at 14 days ago from European Centre for Disease Prevention and Control (via https://www.ecdc.europa.eu/en/publications-data/threat-asses)
Circulating respiratory viruses, including influenza viruses, SARS-CoV-2 and RSV, all contribute to pressure on healthcare systems during winter in the EU/EEA. In a typical season, influenza causes substantial ... Alharby, T.N., Alanazi, M., Khan, K.U. et al. Identifying antivirals against influenza PA endonuclease with machine learning-based activity prediction, DFT optimization, and molecular dynamics simulation. Mol Divers (2025). Abstract
submitted by kickingbird at 14 days ago from Mol Divers (2025) (via https://link.springer.com/article/10.1007/s11030-025-11403-3)
Increasing concern about highly pathogenic avian influenza A (H5N1) is prompting the development of new antivirals directed toward conserved viral entities that are resistant to mutational escape. Here, ... Zhao, Z., Tian, J., Bai, X., Li, M., Song, X., Li,. Epidemiology, evolution, and biological characteristics of avian influenza a (H11) viruses from wild birds. Virulence. Abstract
submitted by kickingbird at 15 days ago from Virulence (via https://www.tandfonline.com/doi/full/10.1080/21505594.2025.2)
H11 subtype avian influenza viruses (AIVs) have been identified in both wild and domestic birds. H11N9 viruses from wild birds provided the NA gene to human H7N9 virus in 2013 in China, which caused five ... Nath H, Arndt A, Mann JT, Baker SF. 0. Tandem split-GFP influenza A viruses for sensitive and accurate replication analyses. Microbiol Spectr 0:e02772-25. Abstract
submitted by kickingbird at 15 days ago from Microbiol Spectr 0:e02772-25 (via https://journals.asm.org/doi/10.1128/spectrum.02772-25)
Reporter influenza A viruses (IAVs) are valuable tools for studying virus fitness, screening antivirals, and assessing host–virus interactions. However, the compact and segmented nature of the IAV genome ... Naito T, Ushirogawa H, Kunishio M, Yano H, Saito S. Live-attenuated influenza virus vaccine strain with an engineered temperature-sensitive and genetically stable viral polymerase variant. J Virol 0:e01390-25. Abstract
submitted by kickingbird at 15 days ago from J Virol 0:e01390-25 (via https://journals.asm.org/doi/10.1128/jvi.01390-25)
Vaccination against seasonal influenza is considered an effective means of reducing morbidity and mortality. Live-attenuated vaccines offer more protection against influenza than inactivated vaccines as ... Oshin Ley Garcia, Tamiru Alkie, Frank van der Me. Serological Evidence of Highly Pathogenic Avian Influenza (H5N1) in Invasive Wild Pigs in Western Canada. Transboundary and Emerging Diseases. Abstract
submitted by kickingbird at 15 days ago from Transboundary and Emerging Diseases (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/2720469)
Influenza A virus (IAV) can infect a wide range of hosts, including wild and domestic pigs. Swine play an important role in influenza evolution and epidemiology due to their ability to get infected with ... Fosse JH, R?mo G, Bonfante F, Myhrvold IK, Soetart. Detection of Antibodies Specific to H5 Avian Influenza Virus in a Sheep in Norway, June 2024, 11 Months After an Outbreak of Highly Pathogenic Avian Influenza in a Nearby Seabird Colony. Influenza Other Respir Viruses. 2025 Nov;19(11). Abstract
submitted by kickingbird at 15 days ago from Influenza Other Respir Viruses. 2025 Nov;19(11) (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70182)
A 2023 outbreak of highly pathogenic avian influenza in seabirds in Norway caused substantial environmental contamination of grazing areas frequented by local sheep. Eleven months later, 220 sheep were ... Martí-Garcia, B., Lean, F.Z.X., Nú?ez, A. et al. Natural infections of highly pathogenic avian influenza virus H5N1 in wild birds between 2020 and 2023 in the UK: a retrospective study with focus on microscopic lesions, viral distribution and neurot. Vet Res 56, 218 (2025). Abstract
submitted by kickingbird at Nov, 19, 2025 from Vet Res 56, 218 (2025) (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Since the emergence of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4 Goose/Guangdong lineage in Europe in 2014, an unprecedented outbreak occurred during the 2021–2022 epidemiological year, ... Cherian, P., Menon, G.I. Modelling a potential zoonotic spillover event of H5N1 influenza. BMC Public Health 25, 3983 (2025). Abstract
submitted by kickingbird at Nov, 19, 2025 from BMC Public Health 25, 3983 (2025) (via https://bmcpublichealth.biomedcentral.com/articles/10.1186/s)
BackgroundHighly Pathogenic Avian Influenza (HPAI) is a prominent candidate for a future human pandemic arising from a zoonotic spillover event. Its best-known subtype is H5N1, with South- or South-East ... Zhao Y, Wang Y, Huang K, Wang F, Wang Y. Influenza a(H1N1) virus infection impairs syncytiotrophoblast functions by promoting ferroptosis through the TNF-α/ISG15/EGR1 axis. Virol J. 2025 Nov 17;22(1):379. Abstract
submitted by kickingbird at Nov, 19, 2025 from Virol J. 2025 Nov 17;22(1):379 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Influenza A virus (IAV) is linked to adverse pregnancy outcomes like spontaneous abortion, preterm birth, and neonatal death. Inhibition of trophoblast cell fusion by IAV infection is a key factor contributing ... Llewellyn, S., Schewe, K.E., Ayaz, S. et al. Replication in human cells supersedes serum antigenic match for the in vivo efficacy of an A/H1N1pdm09 LAIV virus. NPJ Vaccines. 2025 Nov 17;10(1):236. Abstract
submitted by kickingbird at Nov, 19, 2025 from NPJ Vaccines. 2025 Nov 17;10(1):236 (via https://www.nature.com/articles/s41541-025-01281-z)
For FluMist?/Fluenz live attenuated influenza vaccine (LAIV), efficient virus replication in human nasal epithelial cells (hNEC) is an important factor in vaccine effectiveness (VE). The necessity of antigenic ... Dizayee BA, Khlef EL. Molecular characterization of a highly pathogenic avian influenza A (H5N4) virus isolated from domestic chickens in Iraq during the 2015 HPAI H5N1 outbreak. Open Vet J. 2025;15(10):5312-5325. Abstract
submitted by kickingbird at Nov, 18, 2025 from Open Vet J. 2025;15(10):5312-5325 (via https://www.openveterinaryjournal.com/?mno=252729)
Background: Influenza viruses continuously threaten avian and mammalian species. After the circulation of highly pathogenic avian influenza (HPAI) H5N1 in 2015 in Iraq, an H5N4 influenza virus emerged ... Rahman M, Uyeki TM, Peiris M, Cardwell JM, Nguipdo. A Cross-Sectional Virological and Sero-Epidemiological Study of Exposures to Avian Influenza A(H5N1) and A(H9N2) Viruses in Live Bird Market Workers in Dhaka, Bangladesh. Influenza Other Respir Viruses. 2025 Nov;19(11):e7. Abstract
submitted by kickingbird at Nov, 18, 2025 from Influenza Other Respir Viruses. 2025 Nov;19(11):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70189)
Background: Avian influenza A viruses (AIVs) are endemic among poultry in Bangladesh sold at live bird markets (LBMs). We assessed virologic and serologic evidence of exposure to AIVs among LBM workers.Methods: ... Wang X, Ma X, Zeng Y, Li C. Unusual neutrophilic morphology in influenza-A-induced septic shock: Blue-green inclusions and phagocytosis of autologous cells in a toddler. Front Cell Infect Microbiol. 2025 Nov 1;15:1684054. Abstract
submitted by kickingbird at Nov, 18, 2025 from Front Cell Infect Microbiol. 2025 Nov 1;15:1684054 (via https://www.frontiersin.org/journals/cellular-and-infection-)
Influenza A virus is a major cause of seasonal respiratory illness, typically self-limiting in children. However, in rare instances, it can lead to fulminant systemic complications such as acute necrotizing ... Granger KL Jr, Gross C, Frank C, Lappin MR. Multisystemic manifestations of highly pathogenic avian influenza (H5N1) in a young domestic shorthair cat. JFMS Open Rep. 2025 Nov 11;11(2):20551169251376559. Abstract
submitted by kickingbird at Nov, 18, 2025 from JFMS Open Rep. 2025 Nov 11;11(2):20551169251376559 (via https://sage.cnpereading.com/paragraph/article/?doi=10.1177%)
Case summary: A 4.5-year-old male castrated, predominantly indoor-housed domestic shorthair cat presented with lethargy, anorexia and fever, progressing rapidly to severe respiratory distress and neurologic ... WPRO. Avian Influenza Weekly Update # 1022: 14 November 2025. WHO. Abstract
submitted by kickingbird at Nov, 17, 2025 from WHO (via https://www.who.int/westernpacific/publications/m/item/avian)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ... Zhu H, He D, Liu S, Fan X, Gao L, Guo L, Zhang Z.. H6N6 Avian Influenza Virus Infection Induced Pyroptosis of M1 Macrophages by Activating Caspase-1. Viruses. 2025; 17(11):1492. Abstract
submitted by kickingbird at Nov, 17, 2025 from Viruses. 2025; 17(11):1492 (via https://www.mdpi.com/1999-4915/17/11/1492)
The H6N6 avian influenza virus has expanded its host range from birds to mammals. Some strains can now bind to human-like receptors, raising concerns about human infection. Although H6N6 is a low-pathogenic ... Facchini M, De Marco MA, Piacentini S, Di Martino. Divergent Avian Influenza H10 Viruses from Sympatric Waterbird Species in Italy: Zoonotic Potential Assessment by Molecular Markers. Microorganisms. 2025; 13(11):2575. Abstract
submitted by kickingbird at Nov, 17, 2025 from Microorganisms. 2025; 13(11):2575 (via https://www.mdpi.com/2076-2607/13/11/2575)
Avian influenza viruses (AIVs) of H10 subtype are able to circulate in domestic and wild bird populations but can also spill over and adapt to mammals, posing a continuous risk to biodiversity conservation, ... 9492 items, 20/Page, Page[5/475][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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