Huang, J., Ma, K., Ding, S., Wang, Y., Xiong, J.,. A CRISPR activation screen identifies CH25H as a restriction factor against influenza viruses by targeting accessible cholesterol. Emerging Microbes & Infections. Abstract
submitted by kickingbird at May, 14, 2026 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Influenza A viruses (IAVs) cause severe outbreaks with high mortality in birds and humans. A deeper understanding of cell-intrinsic defense mechanisms against influenza viruses is therefore crucial for ... Steiner J, Mwanga M, et al. Concurrent Detection of Swine-Origin Influenza A(H1N1) Virus in Pigs and Farmer, Switzerland. Emerg Infect Dis. 2026 Jun. Abstract
submitted by kickingbird at May, 14, 2026 from Emerg Infect Dis. 2026 Jun (via https://wwwnc.cdc.gov/eid/article/32/6/25-1487_article)
We report zoonotic transmission of Eurasian avian-like swine influenza A(H1N1) virus from pigs to a farmer. The pigs and farmer experienced influenza-like illness. Whole-genome sequencing revealed >99.9% ... Eszter Kovács, etc.,al. H5N1 2.3.4.4b HA E190D and Q226H mutations, picked up as minority variants in a patient, result in an inability to bind sialic acid. Virology. Abstract
submitted by kickingbird at May, 13, 2026 from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
A human infection with clade 2.3.4.4b H5N1 influenza A virus in Canada revealed minority variants E190D and Q226H in the hemagglutinin (HA) receptor-binding site (RBS). Because mutations at positions 190 ... Zhiyuan Liu, etc.,al. Gga-miR-449c suppresses H9N2 influenza virus replication via targeting the viral genome and suppressor of cytokine signaling 3. International Journal of Biological Macromolecules. Abstract
submitted by kickingbird at May, 13, 2026 from International Journal of Biological Macromolecules (via https://www.sciencedirect.com/science/article/abs/pii/S01418)
Avian influenza virus is a globally prevalent pathogen in poultry populations, causing severe economic losses to the poultry industry worldwide. In the present study, we demonstrate that miR-449c generates ... Chen X, Zheng X, Zhang L, Cai X, Hong X, Hou S, Ma. Long noncoding RNA#61 synergizes with viral PA-X to augment pyroptosis and attenuate the virulence of highly pathogenic H5N1 influenza virus in mice. J Virol 0:e02214-25. Abstract
submitted by kickingbird at May, 13, 2026 from J Virol 0:e02214-25 (via https://journals.asm.org/doi/10.1128/jvi.02214-25)
Long non-coding RNAs (LncRNAs) play pivotal regulatory roles in various biological processes, notably in immune regulation and viral infection. We previously identified the broad anti-influenza activity ... Chen Bin, etc.,al. Analysis of Avian Influenza Virus Contamination in Poultry-Related Environments in Shaanxi Province from 2020 to 2024. Chinese Journal of Epidemiology 2026, 47(03):515. Abstract
submitted by kickingbird at May, 13, 2026 from Chinese Journal of Epidemiology 2026, 47(03):515 (via http://chinaepi.icdc.cn/zhlxbx/ch/reader/view_abstract.aspx?)
Objective: To analyze the avian influenza virus (AIV) contamination in poultry-related environments in Shaanxi Province and provide a reference for strengthening regional avian influenza prevention and ... Shen Y, Ma C, Zhang D, Shi W, Duan W, Li J, Zhang. Influenza Vaccine Effectiveness in School Outbreaks During a A(H3N2) Subclade K (J.2.4.1)-Dominated Season in Beijing, China, 2025-26. Int J Infect Dis. 2026 May 9:108777. Abstract
submitted by kickingbird at May, 13, 2026 from Int J Infect Dis. 2026 May 9:108777 (via https://www.ijidonline.com/article/S1201-9712(26)00412-1/ful)
Background: Schools are high-risk settings for influenza transmission. During the 2025-26 Northern Hemisphere season, influenza A(H3N2) subclade K (J.2.4.1) rapidly emerged and became predominant, but ... Giacinti JA, Signore A, Torchetti M, Enrique Valde. North American perspective on the highly pathogenic avian influenza H5Nx clade 2.3.4.4b outbreak (November 2021 - March 2025). Can J Microbiol. 2026 May 11. Abstract
submitted by kickingbird at May, 12, 2026 from Can J Microbiol. 2026 May 11 (via https://cdnsciencepub.com/doi/10.1139/cjm-2025-0275)
Influenza A (H5Nx) highly pathogenic avian influenza viruses of clade 2.3.4.4b were first detected in North America in late 2021, initiating a multi-year outbreak unprecedented in geographic extent, duration, ... WPRO. Avian Influenza Weekly Update # 1044: 8 May 2026. WHO. Abstract
submitted by kickingbird at May, 11, 2026 from WHO (via https://www.who.int/westernpacific/publications/m/item/avian)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ... Nian YunPeng etc.,al. Investigation and Management of the First Human Case of Avian Influenza A(H10N3) Virus Infection in Northern China. Chinese Journal of Epidemiology 2026, 47(02):275. Abstract
submitted by kickingbird at May, 11, 2026 from Chinese Journal of Epidemiology 2026, 47(02):275 (via http://chinaepi.icdc.cn/zhlxbx/ch/reader/view_abstract.aspx?)
Objective: To analyze the epidemiological characteristics and field investigation findings of the first human case of H10N3 avian influenza virus infection in northern China, providing a reference for ... Michelle Wille, etc.,al. [preprint]Migratory bird and marine mammal surveillance fails to find evidence for an HPAI H5N1 2.3.4.4b incursion into Australia in 2025. https://doi.org/10.64898/2026.05.07.722556. Abstract
submitted by kickingbird at May, 11, 2026 from https://doi.org/10.64898/2026.05.07.722556 (via https://www.biorxiv.org/content/10.64898/2026.05.07.722556v1)
The panzootic caused by high pathogenicity avian influenza (HPAI) H5N1 clade 2.3.4.4b has been devastating for animals, globally. Despite global spread, the virus remains absent in Oceania. Herein we report ... Grace E. Quirk, etc.,al. [preprint]Variable transmission efficiency of mammalian origin HPAI D1.1 H5N1 strains in ferrets. https://doi.org/10.64898/2026.05.07.722809. Abstract
submitted by kickingbird at May, 11, 2026 from https://doi.org/10.64898/2026.05.07.722809 (via https://www.biorxiv.org/content/10.64898/2026.05.07.722809v1)
Highly pathogenic avian influenza H5N1 2.3.4.4b genotype D1.1 lineage continues to predominate in the United States wild bird population and has spilled over into dairy cattle three independent times. ... Ruan Z, Deng B, Yin W, Ma F, Lu Y, Wang H. Development of a nano-emulsion and evaluation of its intradermal adjuvant function of Swine Influenza H3N2 Vaccine. Virol J. 2026 May 8. Abstract
submitted by kickingbird at May, 11, 2026 from Virol J. 2026 May 8 (via https://link.springer.com/article/10.1186/s12985-026-03184-4)
Background: Intradermal (ID) immunization is a potent vaccination strategy, but its potential is limited by the lack of adjuvants that can effectively enhance immune responses while minimizing local skin ... Azbida M, Ferjani S, Elahmer O, Osman R, Shenaishe. Sentinel Surveillance of Influenza A in Libya: Subtyping and Genomic Analysis During Recent Seasons (2022–2024). Tropical Medicine and Infectious Disease. 2026; 11. Abstract
submitted by kickingbird at May, 11, 2026 from Tropical Medicine and Infectious Disease. 2026; 11 (via https://www.mdpi.com/2414-6366/11/5/127)
Influenza sentinel surveillance in Libya was formally established in 2022 by the Libyan National Center for Disease Control (NCDC). Between 2022 and 2024, a total of 1864 nasopharyngeal specimens were ... Zhao, Y., Liu, C., Li, Y. et al. Genetic and biological characterization of H9N2 avian influenza viruses isolated from swine in China. BMC Vet Res (2026). Abstract
submitted by kickingbird at May, 9, 2026 from BMC Vet Res (2026) (via https://link.springer.com/article/10.1186/s12917-026-05501-z)
Background: H9N2 avian influenza virus (AIV) has been circulating in poultry in China for decades and are undergoing adaptation to mammals, posing potential pandemic risks. To investigate the prevalence ... Lu Qingxia, Zhang Qingrui, Zhang Jiaqi, Zhu Xiangc. Retrospective Investigation on an Outbreak of Human-Swine Co-infection with H1 Subtype Influenza Virus in Hubei Province. DOI: 10.3969/j.issn.1005-944X.2026.04.002. Abstract
submitted by kickingbird at May, 9, 2026 from DOI: 10.3969/j.issn.1005-944X.2026.04.002 (via http://www.flu.org.cn/scn/article-25913.html)
Based on an outbreak of human-swine co-infection with H1 subtype influenza virus occurred on a farm in Hubei Province in 2023，the process of investigation and response，as well as related data were reviewed，the ... Richard J Sugrue, Richard Sutejo, Boon Huan Tan. [preprint]Evaluating the use of siRNA to silence the expression of the H5N2 virus polymerase genes as strategy to block the transmission of the avian H5N2 virus in mammalian cells. https://doi.org/10.64898/2026.05.04.722578. Abstract
submitted by kickingbird at May, 9, 2026 from https://doi.org/10.64898/2026.05.04.722578 (via https://www.biorxiv.org/content/10.64898/2026.05.04.722578v1)
We prepared siRNA libraries against the H5N2 virus NP gene, and the PA, PB1 and PB2 genes that express the proteins that form the virus polymerase complex. The antiviral activity of the siRNA libraries ... Josephine von Kempis, etc.,al. [preprint]Opposing cell type preferences for binding and replication shape influenza A virus infection in human airways. https://doi.org/10.64898/2026.05.04.722582. Abstract
submitted by kickingbird at May, 9, 2026 from https://doi.org/10.64898/2026.05.04.722582 (via https://www.biorxiv.org/content/10.64898/2026.05.04.722582v1)
Influenza A viruses (IAVs) pose a persistent threat to human health through seasonal epidemics and zoonotic spillover from avian reservoirs. As respiratory pathogens, they primarily target the airway epithelium. ... Tamiru N. Alkie et al. Mammary and respiratory infection of sheep with H5Nx clade 2.3.4.4b viruses with milk-mediated transmission to lambs. Sci. Adv.12,eaed1287(2026). Abstract
submitted by kickingbird at May, 9, 2026 from Sci. Adv.12,eaed1287(2026) (via https://www.science.org/doi/10.1126/sciadv.aed1287)
H5Nx clade 2.3.4.4b viruses are evolving rapidly, expanding host ranges and threatening animal and public health. In the US, genotype B3.13 dominates dairy outbreaks, while D1.1 is linked to fewer cases. ... Kieran TJ, Maines TR, Belser JA. Limited ´heft´ of weight-based outcomes in predicting influenza A virus disease severity in ferrets. PLoS Comput Biol. 2026 May 8;22(5):e1014210. Abstract
submitted by kickingbird at May, 9, 2026 from PLoS Comput Biol. 2026 May 8;22(5):e1014210 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Studies evaluating viral pathogenicity in small mammalian models often quantify disease severity using the magnitudes of temperature rise and weight loss post-challenge. However, no rigorous assessment ... 10190 items, 20/Page, Page[5/510][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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