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2025-12-5 14:43:57
Article

Aawar MA, Srivastava A. Random Forest of epidemiological models for Influenza forecasting. Epidemics. 2025 Oct 21;53:100862.  Abstract  
submitted by kickingbird at Oct, 26, 2025 from Epidemics. 2025 Oct 21;53:100862 (via https://www.sciencedirect.com/science/article/pii/S175543652)
Forecasting the hospitalizations caused by the Influenza virus is vital for public health planning so hospitals can be better prepared for an influx of patients. Many forecasting methods have been used ...

Al-Dalawi L, Yang J, Blanchard AM, Clark M, Chang. Research note: Use of in vitro and in ovo approaches to characterise avian influenza viruses and assess species specific responses to infection. Poult Sci. 2025 Oct 19;104(12):105987.  Abstract  
submitted by kickingbird at Oct, 26, 2025 from Poult Sci. 2025 Oct 19;104(12):105987 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Circulation of avian influenza viruses (AIVs) in domestic and wild birds poses a major health threat, requiring a rapid approach to characterize and identify high-risk strains. We evaluated virus replication ...

Cardenas M, Compton S, Hunt A, Chopra P, Perez DR,. Protocol to measure the kinetics of MHC class II-influenza A binding using biolayer interferometry. STAR Protoc. 2025 Oct 23;6(4):104155.  Abstract  
submitted by kickingbird at Oct, 26, 2025 from STAR Protoc. 2025 Oct 23;6(4):104155 (via https://www.sciencedirect.com/science/article/pii/S266616672)
Recent work has shown that major histocompatibility complex (MHC) class II is a functional receptor for some influenza A virus (FLUAV) subtypes. Here, we present a protocol to measure the kinetics of MHC ...

Hay JA, Zhu H, Jiang CQ, Kwok KO, Shen R, Kucharsk. Reconstructed influenza A/H3N2 infection histories reveal variation in incidence and antibody dynamics over the life course. PLoS Biol. 2024 Nov 7;22(11):e3002864. doi: 10.137.  Abstract  
submitted by kickingbird at Oct, 25, 2025 from PLoS Biol. 2024 Nov 7;22(11):e3002864. doi: 10.137 (via https://journals.plos.org/plosbiology/article?id=10.1371/jou)
Humans experience many influenza infections over their lives, resulting in complex and varied immunological histories. Although experimental and quantitative analyses have improved our understanding of ...

Zhang J, Cao R, Wang Y, Sun Y, Ji X, Liu P, Liu K,. Influenza virus infection reprograms cholesterol biosynthesis to facilitate virus replication by the TAK1-RORγ axis. PLoS Pathog. 2025 Oct 24;21(10):e1013646.  Abstract  
submitted by kickingbird at Oct, 25, 2025 from PLoS Pathog. 2025 Oct 24;21(10):e1013646 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Infection and replication of enveloped viruses require host cells to supply substantial amounts of cellular cholesterol for processes such as binding, entry, trafficking, assembly, and budding. However, ...

Sung-dae Park, Yeonsu Oh, Dae Sung Yoo. Combating highly pathogenic avian influenza in South Korea: A 15-year retrospective and forward-looking study. Preventive Veterinary Medicine.  Abstract  
submitted by kickingbird at Oct, 25, 2025 from Preventive Veterinary Medicine (via https://www.sciencedirect.com/science/article/abs/pii/S01675)
Highly Pathogenic Avian Influenza (HPAI), caused by the Orthomyxoviridae family of RNA viruses, poses a serious threat to the global poultry industry, resulting in severe economic losses and raising public ...

Tommaso Alfonsi et al. Lightweight multiscale early warning system for influenza A spillovers. Sci. Adv.11,eadz7312(2025).  Abstract  
submitted by kickingbird at Oct, 25, 2025 from Sci. Adv.11,eadz7312(2025) (via https://www.science.org/doi/10.1126/sciadv.adz7312)
Spillovers of zoonotic Influenza A viruses (IAVs) into farmed animals and humans have the potential to trigger epidemics or even global pandemics. We introduce FluWarning, a highly efficient and elegant ...

Taeyong Kwon Kwon, etc.,al. [preprint]Pigs lacking Natural Killer T cells have altered cellular responses to influenza. https://doi.org/10.1101/2025.10.23.684238.  Abstract  
submitted by kickingbird at Oct, 25, 2025 from https://doi.org/10.1101/2025.10.23.684238 (via https://www.biorxiv.org/content/10.1101/2025.10.23.684238v1)
It is increasingly recognized that innate T cells such as natural killer T (NKT) cells, mucosal associated invariant T (MAIT) cells, and γδ T cells play an important role in shaping adaptive immune responses ...

Larsen, B.B., Kimchi, O., Dunkley, O.R.S. et al. RNA structure modulates Cas13 activity and enables mismatch detection. Nat Biotechnol (2025).  Abstract  
submitted by kickingbird at Oct, 25, 2025 from Nat Biotechnol (2025) (via https://link.springer.com/article/10.1038/s41587-025-02868-6)
Cas13 is activated by the hybridization of a CRISPR RNA to a complementary single-stranded RNA protospacer in a target RNA. While Cas13 is not activated by double-stranded RNA in vitro, it robustly targets ...

Zhang C, Jin Y, Cui H, Wang Z, Chen Z, Zhang L, So. Cross-Species Transmission Risks of a Quail-Origin H7N9 Influenza Virus from China Between Avian and Mammalian Hosts. Viruses. 2025; 17(10):1402.  Abstract  
submitted by kickingbird at Oct, 25, 2025 from Viruses. 2025; 17(10):1402 (via https://www.mdpi.com/1999-4915/17/10/1402)
The H7N9 influenza viruses, which are capable of causing severe respiratory syndrome in humans, were first discovered to infect humans in 2013 and continue to pose a persistent public health threat. Quail ...

Leach JR, Oo A, Nogales A, Bosch SI, Martínez-Sobr. LAIV Mutations Selectively Alter Influenza Viral RNA Polymerase Function, Favoring Transcription over Genome Synthesis. Viruses. 2025; 17(11):1412.  Abstract  
submitted by kickingbird at Oct, 25, 2025 from Viruses. 2025; 17(11):1412 (via https://www.mdpi.com/1999-4915/17/11/1412)
Influenza viruses cause mild to severe lower respiratory infections, sometimes resulting in hospitalization and death. Vaccination remains the primary prophylactic strategy. Live attenuated influenza vaccines ...

Bekshin Z, Temirbekova A, Nurbekova Z, Amirkhanova. Epidemiology, Virology, and Control of Highly Pathogenic Avian Influenza in Kazakhstan. Pathogens. 2025; 14(11):1084.  Abstract  
submitted by kickingbird at Oct, 25, 2025 from Pathogens. 2025; 14(11):1084 (via https://www.mdpi.com/2076-0817/14/11/1084)
This review analyzed the epidemiology and impact of HPAI (H5N1 and H5N8) in migratory birds and poultry in Kazakhstan, with a special focus on outbreaks from 2005 to 2024. A comprehensive bibliographic ...

Ihazmade, H., Regragui, Z., Bimouhen, A. et al. Impact of IFITM3 rs12252 and IFNAR2 rs2236757 SNP polymorphisms on influenza virus infection outcomes in Moroccan patients. Mol Biol Rep 53, 2 (2026).  Abstract  
submitted by kickingbird at Oct, 25, 2025 from Mol Biol Rep 53, 2 (2026) (via https://link.springer.com/article/10.1007/s11033-025-11144-4)
BackgroundSeasonal influenza is a crucial public health concern. Recent populationalstudies, confirmed the involvement of several signaling proteins on the outcome of theinfection. The IFITM3 and IFNAR2 ...

Wachsmuth-Melm, M., Peterl, S., O’Riain, A. et al. Visualizing influenza A virus assembly by in situ cryo-electron tomography. Nat Commun 16, 9394 (2025).  Abstract  
submitted by kickingbird at Oct, 25, 2025 from Nat Commun 16, 9394 (2025) (via https://link.springer.com/article/10.1038/s41467-025-65117-z)
Influenza A virus (IAV) forms pleomorphic particles that package eight ribonucleoprotein complexes (vRNPs), each carrying a distinct RNA genome segment. vRNPs assemble in the nucleus and undergo selective ...

Tsuneki-Tokunaga A, Komatsu M, Perdana WY, Nishiya. Epidemic influenza virus strains with high growth capability induce severe inflammatory response in vivo. Virology. 2025 Oct 15;613:110717.  Abstract  
submitted by kickingbird at Oct, 24, 2025 from Virology. 2025 Oct 15;613:110717 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Influenza epidemics occur worldwide and impose a substantial socioeconomic burden. In our previous studies, epidemic influenza virus strains isolated from seasonal influenza patient specimens exhibited ...

Takizawa N, Higashi K, Kawaguchi RK, Gotoh Y, Haya. Concentration-dependent formation of intersegment interactions in the viral inclusions of influenza A virus infected cells. iScience. 2025 Sep 22;28(10):113606.  Abstract  
submitted by kickingbird at Oct, 24, 2025 from iScience. 2025 Sep 22;28(10):113606 (via https://www.cell.com/iscience/fulltext/S2589-0042(25)01867-X)
The influenza A virus genome consists of eight RNA segments; each incorporated into a virion. It has been proposed that intersegment interactions bundle these segments, and viral inclusions, which contain ...

Zhao Y, Han L, Sang H, Yang P, Xiao Y, Hou Y. Genetic Diversity and Evolution of H1N1 Subtype Swine Influenza Virus in China: A Comprehensive Analysis from 1977 to 2020. Evolution. 2025 Oct 22:qpaf213.  Abstract  
submitted by kickingbird at Oct, 23, 2025 from Evolution. 2025 Oct 22:qpaf213 (via https://academic.oup.com/evolut/advance-article/doi/10.1093/)
Swine influenza virus (SIV) is a highly contagious respiratory pathogen that causes significant economic losses in the swine industry and poses a potential health risk to humans. This study investigated ...

Liu D, Leung KY, Zhang R, Lam HY, Fan Y, Xie X, Ch. Efficacy of Oseltamivir Against Seasonal Influenza H1N1 and the Efficacy of a Novel Combination Treatment In Vitro and In Vivo in Mouse Studies. Influenza Other Respir Viruses. 2025 Oct;19(10):e7.  Abstract  
submitted by kickingbird at Oct, 23, 2025 from Influenza Other Respir Viruses. 2025 Oct;19(10):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70176)
Background: Influenza surveillance and drug resistance testing have always been central to clinical efforts. Therefore, researching the virus characteristics and antiviral drugs is essential.Method: The ...

Singh G, Assato P, Fitz I, Kafle S, Richt JA. Differential Host Responses and Viral Replication of Highly Pathogenic Avian Influenza H5N1 Strains in Diverse Cell Lines with a Raw Milk Supplement. Life. 2025; 15(10):1625.  Abstract  
submitted by kickingbird at Oct, 22, 2025 from Life. 2025; 15(10):1625 (via https://www.mdpi.com/2075-1729/15/10/1625)
The highly pathogenic avian influenza (HPAI) H5N1 virus poses a growing global health threat, particularly following its unprecedented spillover into dairy cattle and subsequent transmission to more than ...

Zhu H, Pu S, He P, Luo J, Gao R. Construction and Research Progress of Animal Models and Mouse Adapted Strains of Seasonal Influenza Virus. Vaccines. 2025; 13(10):1077.  Abstract  
submitted by kickingbird at Oct, 22, 2025 from Vaccines. 2025; 13(10):1077 (via https://www.mdpi.com/2076-393X/13/10/1077)
Influenza viruses, featured by high variability, pose a persistent public health threat because of an annual seasonal epidemic in the world and irregular global pandemic, requiring animal models to elucidate ...

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