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2025-12-5 21:04:46
Article

Qitao Jia and others. MetaFluAD: meta-learning for predicting antigenic distances among influenza viruses. Briefings in Bioinformatics, Volume 25, Issue 5.  Abstract  
submitted by kickingbird at Aug, 20, 2024 from Briefings in Bioinformatics, Volume 25, Issue 5 (via https://academic.oup.com/bib/article/25/5/bbae395/7731492)
Influenza viruses rapidly evolve to evade previously acquired human immunity. Maintaining vaccine efficacy necessitates continuous monitoring of antigenic differences among strains. Traditional serological ...

Liu L, Li Z, Liu J, Li X, Zhou J, Xiao N, Yang L,. Effects of different HA and NA gene combinations on the growth characteristics of the H3N8 influenza candidate vaccine virus. Vaccine X. 2024 Jul 18;19:100531.  Abstract  
submitted by kickingbird at Aug, 20, 2024 from Vaccine X. 2024 Jul 18;19:100531 (via https://www.sciencedirect.com/science/article/pii/S259013622)
Since 2022, three human cases of a novel H3N8 avian influenza virus infection have been reported in three provinces in China. Specific vaccines are important means of preparing for the potential influenza ...

Colby T Ford, etc.,al. [preprint]Large-Scale Computational Modeling of H5 Influenza Variants Against HA1-Neutralizing Antibodies. https://doi.org/10.1101/2024.07.14.603367.  Abstract  
submitted by kickingbird at Aug, 20, 2024 from https://doi.org/10.1101/2024.07.14.603367 (via https://www.biorxiv.org/content/10.1101/2024.07.14.603367v3)
In June 2024, the United States Department of Agriculture released a report that showed over 300 samples from 2022-2024 of highly pathogenic avian influenza have been detected in mammals. To date, the ...

Shohaimi SA, Leow BL, Mohd Yusop FF, Sidik MR, Bar. Sequence analysis and molecular characterization of low pathogenic avian influenza H9N2 virus isolated from chickens in Sabah. Trop Biomed. 2024 Jun 1;41(2):183-189.  Abstract  
submitted by kickingbird at Aug, 19, 2024 from Trop Biomed. 2024 Jun 1;41(2):183-189 (via https://msptm.org/files/Vol41No2/tb-41-2-008-Shohaimi-S-A.pd)
Low pathogenic avian influenza (LPAI) subtype H9N2 is a causative agent that has raised increasing concern about its impact on poultry and potential public health threats. Even though H9N2 is endemic in ...

Owuor DC, de Laurent ZR, Oketch JW, Murunga N, Oti. Phylogeography and reassortment patterns of human influenza A viruses in sub-Saharan Africa. Sci Rep. 2024 Aug 16;14(1):18987.  Abstract  
submitted by kickingbird at Aug, 18, 2024 from Sci Rep. 2024 Aug 16;14(1):18987 (via https://www.nature.com/articles/s41598-024-70023-3)
The role of sub-Saharan Africa in the global spread of influenza viruses remains unclear due to insufficient spatiotemporal sequence data. Here, we analyzed 222 codon-complete sequences of influenza A ...

Du L, Hou YN, Fu DD, Li J, Ao J, Ma AX, Wan QQ, Wa. Revealing Different Pathways for Influenza A Virus To Reach Microtubules after Endocytosis by Quantum Dot-Based Single-Virus Tracking. ACS Nano. 2024 Aug 14.  Abstract  
submitted by kickingbird at Aug, 15, 2024 from ACS Nano. 2024 Aug 14 (via https://pubs.acs.org/doi/10.1021/acsnano.4c05261)
Actin- and microtubule (MT)-based transport systems are essential for intracellular transport. During influenza A virus (IAV) infection, MTs provide long tracks for virus trafficking toward the nucleus. ...

Russell SL, Andrew CL, Yang KC, Coombe M, McGregor. Descriptive epidemiology and phylogenetic analysis of highly pathogenic avian influenza H5N1 clade 2.3.4.4b in British Columbia (B.C.) and the Yukon, Canada, September 2022 to June 2023. Emerg Microbes Infect. 2024 Aug 15:2392667.  Abstract  
submitted by kickingbird at Aug, 15, 2024 from Emerg Microbes Infect. 2024 Aug 15:2392667 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Surveillance data from wildlife and poultry was used to describe the spread of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b in British Columbia (B.C.) and the Yukon, Canada from September ...

Yu J, Shang C, Deng X, Jia J, Shang X, Wang Z, Zhe. Time-resolved scRNA-seq reveals transcription dynamics of polarized macrophages with influenza A virus infection and antigen presentation to T cells. Emerg Microbes Infect. 2024 Aug 12:2387450.  Abstract  
submitted by kickingbird at Aug, 15, 2024 from Emerg Microbes Infect. 2024 Aug 12:2387450 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Throughout history, the influenza A virus has caused numerous devastating global pandemics. Macrophages, as pivotal innate immune cells, exhibit a wide range of immune functions characterized by distinct ...

Chi X, Huang G, Wang L, Zhang X, Liu J, Yin Z, Guo. A small protein encoded by PCBP1-AS1 is identified as a key regulator of influenza virus replication via enhancing autophagy. PLoS Pathog. 2024 Aug 13;20(8):e1012461.  Abstract  
submitted by kickingbird at Aug, 15, 2024 from PLoS Pathog. 2024 Aug 13;20(8):e1012461 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Many annotated long noncoding RNAs (lncRNAs) contain small open reading frames (sORFs), some of which have been demonstrated to encode small proteins or micropeptides with fundamental biological importance. ...

Zhang Y, Li L, Xin X, Chang L, Luo H, Qiao W, Xia. Effects of H9N2 avian influenza virus infection on metabolite content and gene expression in chick DF1 cells. Poult Sci. 2024 Jul 30;103(10):104125.  Abstract  
submitted by kickingbird at Aug, 15, 2024 from Poult Sci. 2024 Jul 30;103(10):104125 (via https://www.sciencedirect.com/science/article/pii/S003257912)
After viral infection, the virus relies on the host cell's complex metabolic and biosynthetic machinery for replication. However, the impact of avian influenza virus (AIV) on metabolites and gene expression ...

Li X, Jia T, Wang K, Wang L, Zhou L, Li M, Zhu W,. The PB2 I714S mutation influenced mammalian adaptation of the H3N2 canine influenza virus by interfering with nuclear import efficiency and RNP complex assembly. Emerg Microbes Infect. 2024 Dec;13(1):2387439.  Abstract  
submitted by kickingbird at Aug, 15, 2024 from Emerg Microbes Infect. 2024 Dec;13(1):2387439 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Avian influenza viruses (AIVs) are the origin of multiple mammal influenza viruses. The genetic determinants of AIVs adapted to humans have been widely elucidated, however, the molecular mechanism of cross-species ...

Forna A, Weedop KB, Damodaran L, Hassell N, Kondor. Sequence-based detection of emerging antigenically novel influenza A viruses. Proc Biol Sci. 2024 Aug;291(2028):20240790.  Abstract  
submitted by kickingbird at Aug, 15, 2024 from Proc Biol Sci. 2024 Aug;291(2028):20240790 (via https://royalsocietypublishing.org/doi/10.1098/rspb.2024.079)
The detection of evolutionary transitions in influenza A (H3N2) viruses' antigenicity is a major obstacle to effective vaccine design and development. In this study, we describe Novel Influenza Virus A ...

Ge X, Chen Y, Wu W, Lu J, Wang Y, Li Z. Safety and effectiveness of baloxavir marboxil and oseltamivir for influenza in children: a real-world retrospective study in China. Front Pediatr. 2024 Jul 29;12:1418321.  Abstract  
submitted by kickingbird at Aug, 14, 2024 from Front Pediatr. 2024 Jul 29;12:1418321 (via https://www.frontiersin.org/journals/pediatrics/articles/10.)
Objectives: To evaluate the safety and effectiveness of baloxavir marboxil (baloxavir) and oseltamivir in pediatric influenza patients in China.Methods: Patients filling a prescription for baloxavir or ...

Zeller, M.A., Carnevale de Almeida Moraes, D., Cia. Reverse zoonosis of the 2022–2023 human seasonal H3N2 detected in swine. npj Viruses 2, 27 (2024).  Abstract  
submitted by kickingbird at Aug, 14, 2024 from npj Viruses 2, 27 (2024) (via https://www.nature.com/articles/s44298-024-00042-4)
The Iowa State University Veterinary Diagnostic Laboratory detected nineteen human-to-swine reverse zoonoses of the 2022–2023 human seasonal H3N2 between November 2022 and November 2023. Cases from seven ...

Sekine, W., Kamiki, H., Ishida, H. et al. Adaptation potential of H3N8 canine influenza virus in human respiratory cells. Sci Rep 14, 18750 (2024).  Abstract  
submitted by kickingbird at Aug, 14, 2024 from Sci Rep 14, 18750 (2024) (via https://www.nature.com/articles/s41598-024-69509-x)
In 2004, the equine-origin H3N8 canine influenza virus (CIV) first caused an outbreak with lethal cases in racing greyhounds in Florida, USA, and then spread to domestic dogs nationwide. Although transmission ...

David L Suarez, etc.,al. [preprint]Testing of retail cheese, butter, ice cream and other dairy products for highly pathogenic avian influenza in the US. https://doi.org/10.1101/2024.08.11.24311811.  Abstract  
submitted by kickingbird at Aug, 13, 2024 from https://doi.org/10.1101/2024.08.11.24311811 (via https://www.medrxiv.org/content/10.1101/2024.08.11.24311811v)
The recent outbreak of highly pathogenic avian influenza (HPAI) in dairy cows has created public health concerns about the potential of consumers being exposed to live virus from commercial dairy products. ...

Lingcai Zhao, etc.,al. Host-specific SRSF7 regulates polymerase activity and replication of influenza A virus. Microbes and Infection.  Abstract  
submitted by kickingbird at Aug, 12, 2024 from Microbes and Infection (via https://www.sciencedirect.com/science/article/pii/S128645792)
Avian influenza viruses crossing the host barrier to infect humans have caused great panic in human society and seriously threatened public health. Herein, we revealed that knockdown of SRSF7 significantly ...

Spackman E. A Review of the Stability of Avian Influenza Virus in Materials from Poultry Farms. Avian Dis. 2023 Sep;67(3):229-236.  Abstract  
submitted by kickingbird at Aug, 12, 2024 from Avian Dis. 2023 Sep;67(3):229-236 (via https://bioone.org/journals/avian-diseases/volume-67/issue-3)
Avian influenza virus (AIV) is widespread among poultry and wild waterfowl. The severity of the disease is variable and the highly pathogenic form can rapidly kill numerous avian species. Understanding ...

Brinkley Raynor Bellotti, etc.,al. [preprint]Challenges and lessons learned from preliminary modeling of with-in herd transmission of highly pathogenic avian influenza H5N1 in dairy cattle. https://doi.org/10.1101/2024.08.06.606397.  Abstract  
submitted by kickingbird at Aug, 11, 2024 from https://doi.org/10.1101/2024.08.06.606397 (via https://www.biorxiv.org/content/10.1101/2024.08.06.606397v1)
The emergence of highly pathogenic avian influenza A H5N1 in dairy cattle raises many questions related to animal health and changes to the risk of an epidemic in humans. We synthesized information currently ...

Nico Joel Halwe, etc.,al. [preprint]Outcome of H5N1 clade 2.3.4.4b virus infection in calves and lactating cows. https://doi.org/10.1101/2024.08.09.607272.  Abstract  
submitted by kickingbird at Aug, 11, 2024 from https://doi.org/10.1101/2024.08.09.607272 (via https://www.biorxiv.org/content/10.1101/2024.08.09.607272v1)
In March 2024, highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b H5N1 infections in dairy cows were first reported from Texas, USA. Rapid dissemination to more than 190 farms in 13 states ...

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